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Hematology Reports
Volume 13
Issue 1
10.4081/hr.2021.8574
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

Hemorrhagic Cystitis: A Successful Outcome for a Challenging Complication in Stem Cell Transplant

by
Sergio Pinzón Mariño
1,*,
Samira Bakali Badesa
2,
María Jesús Viso Soriano
2 and
Isabel Izquierdo Garcia
1
1
Department of Hematology and Hemotherapy, Avenida Cesareo Alierta Number 10—Right Staircase—5th Floor—Door Centro, 50009 Zaragoza, Spain
2
Department of Anatomical Pathology, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2021, 13(1), 8574; https://doi.org/10.4081/hr.2021.8574
Submission received: 3 April 2020 / Revised: 6 August 2020 / Accepted: 15 October 2020 / Published: 12 March 2021

Abstract

Hemorrhagic cystitis (HC) secondary to BK polyomavirus (BKPyV) is a frequent complication related to allogenic stem cell transplantation. With an important morbidity and mortality, this disease doesn’t have a stablished standard treatment or prophylaxis strategies. At this moment, the supportive therapies approved to treat included hyperhydration, forced diuresis and transfusion support. Cidofovir is a nucleotide analog of deoxycytidine monophosphate against DNA viruses and it has been described for the treatment of BKPyV-HC, but at this moment, is not a front-line therapy. We report a successful case after the use of Cidofovir without Probenecid. No adverse effect was developed under the treatment, and after 4 weeks of treatment, the patient achieved an excellent response.
Keywords: BK virus; cidofovir; hematopoietic stem cell transplantation; virus-associated hemorrhagic cystitis BK virus; cidofovir; hematopoietic stem cell transplantation; virus-associated hemorrhagic cystitis

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MDPI and ACS Style

Pinzón Mariño, S.; Bakali Badesa, S.; Viso Soriano, M.J.; Izquierdo Garcia, I. Hemorrhagic Cystitis: A Successful Outcome for a Challenging Complication in Stem Cell Transplant. Hematol. Rep. 2021, 13, 8574. https://doi.org/10.4081/hr.2021.8574

AMA Style

Pinzón Mariño S, Bakali Badesa S, Viso Soriano MJ, Izquierdo Garcia I. Hemorrhagic Cystitis: A Successful Outcome for a Challenging Complication in Stem Cell Transplant. Hematology Reports. 2021; 13(1):8574. https://doi.org/10.4081/hr.2021.8574

Chicago/Turabian Style

Pinzón Mariño, Sergio, Samira Bakali Badesa, María Jesús Viso Soriano, and Isabel Izquierdo Garcia. 2021. "Hemorrhagic Cystitis: A Successful Outcome for a Challenging Complication in Stem Cell Transplant" Hematology Reports 13, no. 1: 8574. https://doi.org/10.4081/hr.2021.8574

APA Style

Pinzón Mariño, S., Bakali Badesa, S., Viso Soriano, M. J., & Izquierdo Garcia, I. (2021). Hemorrhagic Cystitis: A Successful Outcome for a Challenging Complication in Stem Cell Transplant. Hematology Reports, 13(1), 8574. https://doi.org/10.4081/hr.2021.8574

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