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Pediatric Reports, Volume 17, Issue 2

2025 April - 25 articles

Cover Story: Routine screening exams for retinopathy of prematurity (ROP) can cause significant stress and pain for preterm neonates. To assess the impacts of these exams on neonatal energy utilization and hypoxia, urinary uric acid-to-creatinine ([UA]/[Cr]) ratios and clinical events (apnea, bradycardia, gastric residuals, and oxygen desaturations) were analyzed pre- and post-exam in subjects on room air (n = 18) or oxygen support (n = 20). A significant time effect (p = 0.010) was observed for [UA]/[Cr], with higher levels at 0–12 (p = 0.023) and 12–24 (p = 0.023) hours post-exam. Newborns on oxygen support had more total (p = 0.028) and severe (p = 0.026) oxygen desaturations post-exam. Thus, ROP exams may increase energy utilization in preterm neonates, and those on oxygen support may be particularly susceptible to oxygen desaturations post-exam. View this paper
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Articles (25)

  • Review
  • Open Access
2 Citations
3,135 Views
22 Pages

Mental Health, Psychological Features and Psychiatric Comorbidity of Adolescents with Atopic Dermatitis: A Review

  • Liborija Lugović-Mihić,
  • Dora Bukal,
  • Lorena Dolački,
  • Lucija Zanze,
  • Ema Barac,
  • Renata Tomašević and
  • Maja Vilibić

Background/Objectives: Adolescence is a sensitive period of development marked by significant changes. The quality of life (QoL) of adolescents with atopic dermatitis (AD) can be substantially impacted by the disease. The chronic nature of AD is part...

  • Article
  • Open Access
3 Citations
1,605 Views
17 Pages

Virtual Reality as a Tool for Upper Limb Rehabilitation in Rett Syndrome: Reducing Stereotypies and Improving Motor Skills

  • Rosa Angela Fabio,
  • Martina Semino,
  • Michela Perina,
  • Matteo Martini,
  • Emanuela Riccio,
  • Giulia Pili,
  • Danilo Pani and
  • Manuela Chessa

Background/Objectives: Rett Syndrome (RTT) is a rare neurodevelopmental disorder that causes the loss of motor, communicative, and cognitive skills. While no cure exists, rehabilitation plays a crucial role in improving quality of life. Virtual Reali...

  • Review
  • Open Access
1,859 Views
15 Pages

Background: Nepal’s diverse geography creates significant challenges for healthcare accessibility, particularly for neonatal care. Rural areas, especially in the mountainous regions, face severe healthcare gaps due to isolation, inadequate infr...

  • Case Report
  • Open Access
2 Citations
1,208 Views
10 Pages

The Gollop–Wolfgang Complex: A Case Report

  • Jun-Bum Kim,
  • Byung-Ryul Lee,
  • Jong-Seok Park,
  • Chang-Hwa Hong,
  • Sai-Won Kwon,
  • Woo-Jong Kim,
  • Soon-Do Wang,
  • Dong-Woo Lee,
  • Kyeung-Min Nam and
  • Ki-Jin Jung

Background: The Gollop–Wolfgang complex is a rare congenital limb deformity characterized by a bifid femur, tibial hemimelia, and ectrodactyly of the hand. First described in 1980, fewer than 200 cases have been reported globally, with an estim...

  • Article
  • Open Access
4 Citations
3,537 Views
17 Pages

Combined Cognitive and Motor Training Improves Reading, Writing and Motor Coordination in Dyslexic Children

  • Amal Ben Dhia,
  • Maria-Pia Bucci,
  • Chokri Naffeti,
  • Helmi Ben Saad,
  • Omar Hammouda and
  • Tarak Driss

Background/Objectives: Different strategies were proposed to enhance dyslexic children’s performance. This study aimed to investigate the effect of combined cognitive and motor training on reading, writing, and motor coordination in dyslexic ch...

  • Article
  • Open Access
2,462 Views
14 Pages

The Penguin Study: A Randomised, Double-Blinded, Equivalence Trial on the Safety and Suitability of an Infant Formula with Partially Hydrolysed 100% Whey Protein

  • Lindsey Otten,
  • Antonia Nomayo,
  • Caroline Gunn,
  • Maher Fuad,
  • Barbara Kuhn-Sherlock,
  • Sophie Gallier,
  • Elisabeth Schelker,
  • Janine Foster and
  • Frank Jochum

Background/Objectives: This study aimed to demonstrate the safety and suitability of an infant formula manufactured from partially hydrolysed whey protein (PHF) compared to standard formula manufactured from intact cow’s milk proteins (IPF; whe...

  • Article
  • Open Access
1,122 Views
13 Pages

Optimizing Pediatric Chest Compressions: A Randomized Crossover Simulation Trial of Over-the-Head vs. Lateral Techniques

  • Malgorzata Kietlinska,
  • Wojciech Wieczorek,
  • Michal Pruc,
  • Lukasz Szarpak,
  • Grazyna Nowak-Starz,
  • Wojciech Flieger,
  • Burak Katipoglu and
  • Monika Tomaszewska

Background/Objectives: Pediatric cardiac arrest poses considerable obstacles, with survival rates markedly inferior to those of adults. Effective chest compressions are essential for enhancing outcomes; nevertheless, the ideal rescuer attitude is sti...

  • Article
  • Open Access
2 Citations
2,811 Views
16 Pages

Aim: Parents’ knowledge of oral health plays a key role in shaping their children’s habits and preventing early childhood caries, particularly through breastfeeding and nutrition. This study aimed to assess parents’ knowledge of how...

  • Review
  • Open Access
1 Citations
6,489 Views
19 Pages

Background: Epidemiological studies have shown that neurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are more prevalent in the general childhood population, compared to ca...

  • Systematic Review
  • Open Access
3,059 Views
16 Pages

Impact of Music Therapy on Neurodevelopment of Preterm Infants and Functional Improvement in Children with Neurological Deficits

  • Filomeni Armakola,
  • Eleni Potamiti,
  • Anna Tsiakiri,
  • Georgios Felekis,
  • Georgia Tsakni,
  • Athanasios Tsivgoulis,
  • Christos Moschovos,
  • Sotirios Giannopoulos,
  • Vasiliki Georgousopoulou and
  • Pinelopi Vlotinou
  • + 1 author

Background/Objectives: The aim of this systematic review is to assess the effect of music therapy initiated during neonatal intensive care unit (NICU) hospitalization on the early neurodevelopment of infants and to evaluate its impact on functional i...

  • Article
  • Open Access
2 Citations
3,089 Views
14 Pages

Influence of Behavioral and Sociodemographic Factors on Dental Caries in Mexican Children

  • Ángel Pérez-Reyes,
  • Julieta Sarai Becerra-Ruiz and
  • Juan Manuel Guzmán-Flores

Background: In Mexico, tooth decay is common among children and is on the rise. A strong relationship exists between behavioral, socioeconomic, demographic, and biological factors and the severity and development of dental caries. Objective: The pres...

  • Article
  • Open Access
4 Citations
4,358 Views
13 Pages

Self-Efficacy and Psychological Well-Being in Adolescents: Evaluating the Moderating Role of Socioeconomic Status and Cultural Factors

  • Giulia Raimondi,
  • James Dawe,
  • Fabio Alivernini,
  • Sara Manganelli,
  • Pierluigi Diotaiuti,
  • Laura Mandolesi,
  • Michele Zacchilli,
  • Fabio Lucidi and
  • Elisa Cavicchiolo

Background/Objectives: Adolescence is a crucial developmental stage characterized by significant psychological and emotional changes. Within the school context, academic self-efficacy (ASE) influences students’ emotional well-being, including p...

  • Article
  • Open Access
1,200 Views
15 Pages

Fathers Matter Too: Investigating Their Role with the P-CRS

  • Alexandro Fortunato,
  • Maria Quintigliano,
  • Costanza Franchini,
  • Marco Lauriola and
  • Anna Maria Speranza

Background: The development of children is shaped by a complex interplay of biological, psychological, and social factors, yet the role of fathers remains underrepresented in research. This study contributes to addressing this gap by examining patern...

  • Article
  • Open Access
1 Citations
2,380 Views
11 Pages

Influence of the Timing of Gender Dysphoria Presentation and Suicidal Behaviors on Internalizing Symptoms, Emotion Dysregulation, and Body Investment in Adolescents Seeking Gender Affirmation

  • Maria Giuseppina Petruzzelli,
  • Federica Annecchini,
  • Flora Furente,
  • Fabio Tarantino,
  • Valeria Carruolo,
  • Elisabetta Lavorato,
  • Maria Pia Riccio,
  • Andrea De Giacomo and
  • Emilia Matera

Studies have consistently shown that gender-diverse youth experience higher rates of internalizing disorders and self-harm behaviors (SH) compared to their cisgender peers. However, there is limited research on how body investment and emotion regulat...

  • Brief Report
  • Open Access
1,169 Views
9 Pages

Maternal and Neonatal Outcomes of Cervical Colonization in Adolescent Pregnancies: A Brief Report

  • Maisa Manasar-Dyrbuś,
  • Jakub Staniczek,
  • Rafał Stojko,
  • Piotr Gibała,
  • Cecylia Jendyk,
  • Ewa Winkowska,
  • Kacper Niziński,
  • Diana Sieroszewska,
  • Aleksander Sieroszewski and
  • Agnieszka Drosdzol-Cop

Objective: This study examines early neonatal adaptation and birth complications in adolescents with term pregnancies who had positive cervical canal cultures upon hospital admission. Methods: This retrospective study analyzed data from 1 January 201...

  • Review
  • Open Access
3 Citations
7,058 Views
32 Pages

Treatments for Eating Disorders in People with Autism Spectrum Disorder: A Scoping Review

  • Rachele Simeon,
  • Giovanni Galeoto,
  • Serena Cracolici,
  • Francescaroberta Panuccio and
  • Anna Berardi

Background: This scoping review aims to synthesize existing evidence on non-pharmacological interventions for managing food selectivity in individuals with autism spectrum disorder (ASD). Specifically, it explores sensory, behavioral, and environment...

  • Article
  • Open Access
5 Citations
22,402 Views
18 Pages

Association Between TikTok Use and Anxiety, Depression, and Sleepiness Among Adolescents: A Cross-Sectional Study in Greece

  • Angeliki Bilali,
  • Aglaia Katsiroumpa,
  • Ioannis Koutelekos,
  • Chrysoula Dafogianni,
  • Parisis Gallos,
  • Ioannis Moisoglou and
  • Petros Galanis

Introduction: TikTok use is increasing, especially among children and adolescents. However, the negative effects of TikTok use have not been sufficiently investigated. Aim: To examine the association between TikTok use and anxiety, depression, and sl...

  • Article
  • Open Access
3,158 Views
15 Pages

Adolescent-Reported Interparental Conflict and Related Emotional–Behavioral Difficulties: The Mediating Role of Psychological Inflexibility

  • Ludovica Giani,
  • Cecilia Amico,
  • Chiara Crepaldi,
  • Marcella Caputi,
  • Simona Scaini,
  • Giovanni Michelini and
  • Barbara Forresi

Background/Objectives: Interparental conflict, with its multiple dimensions, represents a risk factor for youth mental health, triggering a series of cascading processes. Despite recent evidence highlighting that psychological inflexibility is a risk...

  • Case Report
  • Open Access
2,450 Views
9 Pages

Approach to Macrodactyly: A Case Report and Diagnostic Algorithm for Syndromic and Isolated Forms

  • Ioannis Kyriakidis,
  • Iordanis Pelagiadis,
  • Nikolaos Katzilakis and
  • Eftichia Stiakaki

Background: Macrodactyly (megalodactyly or digital gigantism) is a rare condition of overgrowth affecting one or more fingers or toes. Methods: We report a case of a 16-year-old Caucasian male with macrodactyly, lipomas, nevi, dysmorphic features, an...

  • Article
  • Open Access
4,549 Views
18 Pages

Background/Objectives: School-Mindfulness-Based Interventions (SMBIs) have shown positive effects on children’s mental health by enhancing emotional regulation and present-moment awareness. This pilot study explored the effects of an SMBI progr...

  • Article
  • Open Access
6 Citations
6,498 Views
12 Pages

Background/Objectives: DNA extraction from dried blood spot (DBS) samples is often applied in neonatal screening programs. Although various methods to extract DNA from DBSs have been described, the optimal approach remains unclear. Therefore, this st...

  • Article
  • Open Access
1,547 Views
15 Pages

Energy Utilization in Premature Neonates Undergoing Screening for Retinopathy of Prematurity

  • Alena M. Pentecost,
  • Danilo S. Boskovic,
  • Alexis Antimo,
  • Udochukwu Oyoyo,
  • Christopher C. Perry,
  • Jennifer Dunbar,
  • Andrew Hopper and
  • Danilyn M. Angeles

Background/Objectives: Premature neonates are at risk for retinopathy of prematurity (ROP) and routinely undergo screening exams that involve substantial physical manipulation, often causing significant signs of pain, despite pain-relieving intervent...

  • Article
  • Open Access
1 Citations
2,399 Views
19 Pages

Objective: This study sought to evaluate the effectiveness of a serious game, that embeds cognitive bias modification for interpretation (CBM-I), in altering the negative interpretive bias of early aged adolescents diagnosed with Attention-Deficit/Hy...

  • Article
  • Open Access
1,468 Views
15 Pages

Association Between Bullying/Cyberbullying and Subjective Vitality in Children and Adolescents: The Mediating Role of Mental Toughness

  • Pablo Ramírez-Espejo,
  • Alba Rusillo-Magdaleno,
  • Alberto Ruiz-Ariza and
  • Manuel J. de la Torre-Cruz

Background: Previous research has examined to what extent the relationship between bullying/cyberbullying (victims and perpetrators) and psychological well-being is mediated by different cognitive–emotional variables. Objectives: The present st...

  • Review
  • Open Access
7 Citations
17,960 Views
34 Pages

Why Do They Do It? The Psychology Behind Antisocial Behavior in Children and Adolescents

  • Marianna Mazza,
  • Francesco Maria Lisci,
  • Ester Maria Marzo,
  • Valeria De Masi,
  • Francesca Abate and
  • Giuseppe Marano

Antisocial Personality Disorder (ASPD) is a complex and often debilitating condition that can emerge from early behavioral disturbances in childhood and adolescence. This narrative review provides a comprehensive overview of the current understanding...

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Pediatr. Rep. - ISSN 2036-7503