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Infectious Disease Reports, Volume 17, Issue 2

April 2025 - 23 articles

Cover Story: This systematic review aimed to describe the demographic data, hemodynamic severity of disease at diagnosis and functional impairment of Brazilian patients with Schistosoma-associated pulmonary arterial hypertension (Sch-PAH). From 461 records identified through database searching, 5 studies were selected for meta-analysis. We demonstrated that patients with Sch-PAH have clinical characteristics similar to those found in other forms of pulmonary arterial hypertension (PAH), with most of the data found in the medical literature being published by a few reference centers in Brazil. Our work sheds light on this relevant but still neglected parasitic tropical disease—one of the leading causes of PAH worldwide. View this paper
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Articles (23)

  • Case Report
  • Open Access
1,411 Views
10 Pages

Severe Anaplasmosis with Multi-Organ Failure in a Patient with Splenectomy: A Case Report

  • Nithin Karnan,
  • Predrag Jancic,
  • Igor Dumic,
  • Emeka Amadi,
  • Vishnu Kommineni,
  • Jelena Stojsavljevic,
  • Aryan Shiari,
  • Melissa Hart,
  • Ra’ed Jabr and
  • Charles W. Nordstrom

Background: Anaplasma phagocytophilum is an emerging tick-borne zoonotic pathogen that typically causes mild infections, which are often successfully managed in outpatient settings. Immunosuppression associated with splenectomy is a well-documented r...

  • Article
  • Open Access
737 Views
10 Pages

Clinical Characteristics and Outcomes of Patients with Cirrhosis Who Develop Infective Endocarditis

  • Erika M. Dorff,
  • Kyle Crooker,
  • Torrance Teng,
  • Tess Hickey,
  • Max HoddWells,
  • Ashwini Sarathy,
  • Sean Muniz,
  • Jennifer Lor,
  • Amy Chang and
  • Devika Singh
  • + 4 authors

Background: Infective endocarditis (IE) is an increasingly common infection that results in significant morbidity and mortality. An important but under-analyzed subpopulation of patients with IE are those with concomitant cirrhosis. This study compar...

  • Article
  • Open Access
986 Views
10 Pages

Improved Sixty-Day Mortality in Candidemia with Antifungal Treatment Within 72 Hours of Fever Onset: A Single-Center Retrospective Study in Rural Japan

  • Koji Hayashi,
  • Chizuru Hashimoto,
  • Kohei Ueda,
  • Yuka Nakaya,
  • Asuka Suzuki,
  • Maho Hayashi,
  • Mamiko Sato and
  • Yasutaka Kobayashi

Introduction: Prognostic factor investigations for candidemia have been conducted in large-scale facilities, leading to significant evidence, including early administration of echinocandin antifungal agents and removal of central venous catheters (CV...

  • Review
  • Open Access
1 Citations
1,476 Views
16 Pages

Introduction: Infectious diseases significantly impact pulmonary vascular disorders, particularly in developing countries where parasitic infections remain prevalent. These infections constitute a substantial yet frequently overlooked contributor to...

  • Perspective
  • Open Access
1 Citations
2,983 Views
21 Pages

This perspective examines the potential oncogenic mechanisms of SARS-CoV-2 through comparative analysis with established cancer-causing viruses, integrating classical virological approaches with artificial intelligence (AI)-driven analysis. The paper...

  • Article
  • Open Access
1 Citations
1,125 Views
11 Pages

Abnormal Neurologic and Motor Function in Newborns Treated for Congenital Syphilis

  • Bruna Silva,
  • Luciana Friedrich,
  • Graziela Biazus,
  • Renata Bueno and
  • Carla Almeida

Background: Congenital syphilis (CS) is a transplacental infection that can lead to many long-term sequelae when not adequately treated; however, knowledge about the motor and neurological signs that newborns (NBs) with CS may present is scarce. Obje...

  • Systematic Review
  • Open Access
1 Citations
1,888 Views
14 Pages

Sickle Cell Disease and Antimicrobial Resistance: A Systematic Review and Meta-Analysis

  • Bismark Opoku-Asare,
  • Onyansaniba K. Ntim,
  • Aaron Awere-Duodu and
  • Eric S. Donkor

Background/Objectives: Antimicrobial resistance (AMR) is increasingly rising due to antimicrobial overuse and misuse. In sickle cell disease (SCD) care, frequent antibiotic use drives the rapid emergence of AMR, threatening treatment options and pati...

  • Review
  • Open Access
13 Citations
5,279 Views
17 Pages

Background: Clostridioides difficile infection (CDI) is a major cause of healthcare-associated infections globally. Understanding variations in CDI incidence and outcomes across settings, populations, and regions is important for guiding prevention s...

  • Systematic Review
  • Open Access
1 Citations
1,359 Views
21 Pages

Fusobacterium Species in Osteoarticular Infections in Childhood—A Systematic Review with Data Synthesis and a Case Series in the Acetabular and Hip Joint Regions

  • Heide Delbrück,
  • Silvia Schröder,
  • Tom Stapper,
  • Sabine Schacht,
  • Angeliki Pappa,
  • Frank Hildebrand and
  • Miriam Katharina Hertwig

Background: In paediatric osteoarticular infections, microorganism detection is unsuccessful in up to 55% of cases, which is not satisfactory for targeted antibiotic therapy. In particular, anaerobic fusobacteria may be underdiagnosed owing to a lack...

  • Article
  • Open Access
2 Citations
2,182 Views
15 Pages

Objectives: We aimed to analyze the landscape of viral respiratory illnesses (VRIs) in a large metropolitan area in Southern California with a focus on the COVID-19 pandemic. Methods: We conducted a retrospective cohort study within the UCLA Health S...

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Infect. Dis. Rep. - ISSN 2036-7449