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Infectious Disease Reports, Volume 17, Issue 1

2025 February - 15 articles

Cover Story: Therapeutic options include topical treatments applied directly to the affected area, oral treatments, essentials oils, and even external therapies, such as laser, iontophoresis, or photodynamic therapy. In some cases, combined treatment may even be necessary and indicated, depending on the location, area of involvement, and the causative agent. Therefore, to prevent diabetic foot ulcers and the downstream effects, there is an urgent need for the treatment of onychomycosis in patients with diabetes and diabetic foot. In severe cases of onychomycosis, there may be subungual lesions; therefore, the use of oral therapies is recommended. Problems emerge when analyzing the possible interactions of the drugs taken by this patient profile with oral antifungal treatments. View this paper
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Articles (15)

  • Review
  • Open Access
5 Citations
3,790 Views
13 Pages

13 February 2025

Background/ Objectives: Long COVID or post-acute sequelae of SARS-CoV-2 infection (PASC) are symptoms that manifest despite passing the acute infection phase. These manifestations encompass a wide range of symptoms, the most common being fatigue, sho...

(This article belongs to the Special Issue Pulmonary Vascular Manifestations of Infectious Diseases)
  • Case Report
  • Open Access
4 Citations
2,956 Views
10 Pages

Atypical Hemolytic Uremic Syndrome Associated with BNT162b2 mRNA COVID-19 Vaccine in a Kidney Transplant Recipient: A Case Report and Literature Review

  • Eleonora Francesca Pattonieri,
  • Marilena Gregorini,
  • Maria Antonietta Grignano,
  • Tefik Islami,
  • Gioacchino D’Ambrosio,
  • Gianluigi Ardissino and
  • Teresa Rampino

11 February 2025

Case Report: We report a case of a 37-year-old female with kidney transplant, who was admitted at our hospital due to worsening renal function, nephrotic proteinuria, and anemia developed 21 days after the second dose of BNT162b2 COVID-19 vaccine (Pf...

(This article belongs to the Section Immunology and Vaccines)
  • Case Report
  • Open Access
4 Citations
5,148 Views
9 Pages

A Report of Two Uncommon Cases of Mycobacterium chelonae with Localized and Disseminated Skin and Soft Tissue Infection

  • Libardo Rueda Prada,
  • Marko Gorasevic,
  • Tatjana Gavrancic,
  • Aayushi J. Rajani,
  • Jason C. Sluzevich,
  • Sangeeta Nair-Collins and
  • Ravi V. Durvasula

Background: Mycobacterium chelonae is a ubiquitous, rapidly growing, nontuberculous mycobacteria that primarily affects immunocompromised patients. The most common presentation is an atypical, chronic skin and soft tissue infection. Due to its high r...

(This article belongs to the Section Tuberculosis and Mycobacteriosis)
  • Review
  • Open Access
1 Citations
4,440 Views
24 Pages

Immune Alterations and Viral Reservoir Atlas in SIV-Infected Chinese Rhesus Macaques

  • Julien A. Clain,
  • Morgane Picard,
  • Henintsoa Rabezanahary,
  • Sonia André,
  • Steven Boutrais,
  • Ella Goma Matsetse,
  • Juliette Dewatines,
  • Quentin Dueymes,
  • Elise Thiboutot and
  • Jérôme Estaquier
  • + 5 authors

Background/Objectives: Over the last decades, our projects have been dedicated to clarifying immunopathological and virological events associated with Human Immunodeficiency Virus (HIV) infection. Methods: By using non-human primate models of pathoge...

(This article belongs to the Special Issue Prevention, Diagnosis and Treatment of Infectious Diseases)
  • Article
  • Open Access
4 Citations
3,280 Views
10 Pages

Impact of Severity of COVID-19 in TB Disease Patients: Experience from an Italian Infectious Disease Referral Hospital

  • Virginia Di Bari,
  • Carlotta Cerva,
  • Raffaella Libertone,
  • Serena Maria Carli,
  • Maria Musso,
  • Delia Goletti,
  • Alessandra Aiello,
  • Antonio Mazzarelli,
  • Angela Cannas and
  • on behalf of the TB-INMI Working Group
  • + 3 authors

Background/Objectives: Tuberculosis (TB) remains a major global health issue, further complicated by the COVID-19 pandemic. This study assesses the clinical outcomes of TB-COVID-19-coinfected patients compared to those with TB disease alone at an Ita...

  • Article
  • Open Access
10 Citations
4,992 Views
15 Pages

Plasma Lipopolysaccharide-Binding Protein (LBP) Is Induced in Critically Ill Females with Gram-Negative Infections—Preliminary Study

  • Alexander Utrata,
  • Niklas Schmidtner,
  • Patricia Mester,
  • Stephan Schmid,
  • Martina Müller,
  • Vlad Pavel and
  • Christa Buechler

Background/Objectives: Men are more susceptible to sepsis than women, but the underlying pathways have not been fully clarified. Lipopolysaccharide-binding protein (LBP) is an acute-phase protein that is highly elevated in sepsis. Experimental eviden...

(This article belongs to the Section Infection Prevention and Control)
  • Article
  • Open Access
2 Citations
3,049 Views
11 Pages

Mpox Cases in Serbia, 2022

  • Petar Đurić,
  • Verica Jovanović,
  • Mitra B. Drakulović,
  • Dragana Plavša,
  • Jovan Malinić,
  • Aleksandar Medarević,
  • Jelena Protić and
  • Nana Mebonia

Background: On 23 July 2022, the World Health Organization (WHO) declared the mpox multi-country outbreak as a Public Health Emergency of International Concern. This study aimed to identify the epidemiological and clinical characteristics of confirme...

  • Article
  • Open Access
1 Citations
1,633 Views
8 Pages

Cytomegalovirus Blood DNAemia in Patients with Severe SARS-CoV-2 Pneumonia

  • Jean-Baptiste Mesland,
  • Christine Collienne,
  • Virginie Montiel,
  • Alexis Werion,
  • Philippe Hantson,
  • Xavier Wittebole,
  • Pierre-François Laterre and
  • Ludovic Gerard

Introduction: Cytomegalovirus (CMV) DNAemia has been described in critically ill patients, including patients with severe acute respiratory syndrome-coronavirus2 (SARS-CoV-2) infection. Our objective is to evaluate the prevalence and clinical impact...

(This article belongs to the Topic Post COVID-19: Latest Advances, Challenges and Methodologies)
  • Article
  • Open Access
5 Citations
7,088 Views
12 Pages

Background/Objectives: In an 18- to 24-month Treatment Phase with once-daily efinaconazole 10% solution, subjects with onychomycosis showed an increased rate of cure at Month 24 versus the phase III trials. In order to further improve efficacy, we in...

(This article belongs to the Section Fungal Infections)
  • Article
  • Open Access
2 Citations
2,308 Views
13 Pages

Early Use of Liraglutide for the Treatment of Acute COVID-19 Infection: An Open-Label Single-Center Phase II Safety Study with Biomarker Profiling

  • Eloara V. M. Ferreira,
  • Rudolf K. F. Oliveira,
  • Reinaldo Salomao,
  • Milena K. C. Brunialti,
  • Martyella B. A. Cardoso,
  • Chien-nien Chen,
  • Lan Zhao and
  • Colm McCabe

Background: Glucagon-like peptide-1 (GLP-1) agonists are an existing treatment option for patients with insulin-resistant states, which elicit further pleiotropic effects related to immune cell recruitment and vascular inflammation. GLP-1 agonists do...

(This article belongs to the Special Issue Pulmonary Vascular Manifestations of Infectious Diseases)
  • Article
  • Open Access
2 Citations
3,305 Views
15 Pages

Etiological Insights and the Role of Individual Factors in Infectious Spondylodiscitis

  • Diana Elena Vulpe,
  • Dana-Georgiana Nedelea,
  • Serban Dragosloveanu,
  • Oana Sandulescu and
  • Cristian Scheau

Objectives: Spondylodiscitis can be caused by various microorganisms and has shown a continuous rise in incidence and mortality. The purpose of our study was to analyze the demographic and laboratory data, as well as comorbidities of patients that we...

  • Systematic Review
  • Open Access
7 Citations
8,793 Views
16 Pages

Treatment of Onychomycosis and the Drug–Drug Interactions in Patients with Diabetes Mellitus and Diabetic Foot Syndrome: A Systematic Review

  • David Navarro-Pérez,
  • Aroa Tardáguila-García,
  • Sara García-Oreja,
  • Francisco Javier Álvaro-Afonso,
  • Mateo López-Moral and
  • José Luis Lázaro-Martínez

Background: This systematic review reports on treatments for onychomycosis in patients with diabetes and the drug interactions with other drugs in regard to the complicated diabetic patient profile. Methods: The recommendations in the preferred repor...

(This article belongs to the Section Fungal Infections)
  • Article
  • Open Access
5 Citations
5,466 Views
17 Pages

Background/Objectives: Vaccine hesitancy, recognized by the WHO as a significant global health threat, undermines vaccination efforts. This study aimed to adapt and validate the Parent Attitudes about Childhood Vaccines (PACV) Survey for Croatian par...

  • Article
  • Open Access
2 Citations
4,114 Views
10 Pages

Zika Virus Infection in Asymptomatic Pregnant Women

  • Kathia Guardado,
  • Nayali López-Balderas,
  • Jaime Morales-Romero,
  • Clara Luz Sampieri,
  • Roberto Zenteno-Cuevas,
  • María Teresa Álvarez-Bañuelos,
  • Ángel Ramos-Ligonio,
  • María Cristina Ortiz-León,
  • Miguel Varela-Cardoso and
  • Hilda Montero

Background/Objectives: Zika disease is caused by the Zika virus (ZIKV) and represents a major public health problem because of the complications in newborn babies from mothers who were infected during pregnancy. It is estimated that 80% of infected p...

(This article belongs to the Section Viral Infections)
  • Article
  • Open Access
3 Citations
4,361 Views
16 Pages

Exercise-Driven Comprehensive Recovery: Pulmonary Rehabilitation’s Impact on Lung Function, Mechanics, and Immune Response in Post-COVID-19 Patients

  • Maysa Alves Rodrigues Brandao-Rangel,
  • Boris Brill,
  • Guilherme Eustáquio Furtado,
  • Catharine Cássia Lanna Freitas-Rolim,
  • Anamei Silva-Reis,
  • Victor Hugo Souza-Palmeira,
  • Renilson Moraes-Ferreira,
  • Vanessa Lopes-Silva,
  • Regiane Albertini and
  • Rodolfo P. Vieira
  • + 6 authors

Introduction: We sought to evaluate the effects of a 12-week pulmonary rehabilitation (PR) program on lung function, mechanics, as well as pulmonary and systemic inflammation in a cohort of 33 individuals with moderate to severe post-COVID-19. Materi...

(This article belongs to the Topic Post COVID-19: Latest Advances, Challenges and Methodologies)
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Infect. Dis. Rep. - ISSN 2036-7449