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Gastroenterology Insights, Volume 16, Issue 4

December 2025 - 14 articles

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Articles (14)

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Review

1,487 Views

19 Pages

Liquid Biopsy in Pancreatic Ductal Adenocarcinoma: Clinical Utility, Trials, and Future Directions

Ahmed Bendari,
Oana Vele,
Brett Baskovich,
Alaa Bendari,
Mona Sebika,
Juan Luis Gomez Marti,
Kritika Krishnamurthy and
Saeed Asiry

Gastroenterol. Insights2025, 16(4), 39;https://doi.org/10.3390/gastroent16040039

19 October 2025

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy marked by late diagnosis, rapid progression, and poor prognosis, with a 5-year survival rate of 2–9%. Traditional tissue biopsy faces limitations in accessibility and real-time moni...

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Article

1,477 Views

11 Pages

Outcomes of EUS-Guided Gallbladder Drainage: A Case Series from a Tertiary Referral Center in Ireland

Mohamed Wael Mohamed,
Olufemi Aoko and
Danny Cheriyan

Gastroenterol. Insights2025, 16(4), 38;https://doi.org/10.3390/gastroent16040038

16 October 2025

Background/Objectives: Cholecystectomy remains the gold-standard treatment for acute cholecystitis. However, in patients deemed unfit for surgery, alternative gallbladder drainage techniques are required. These include percutaneous gallbladder draina...

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Article

1,690 Views

15 Pages

Divergent Trends in Esophageal Adenocarcinoma and Squamous Cell Carcinoma Incidence, 2000–2022

Vinit H. Majmudar,
Kyle Nguyen-Ngo and
Michael Tadros

Gastroenterol. Insights2025, 16(4), 37;https://doi.org/10.3390/gastroent16040037

9 October 2025

Background: Esophageal adenocarcinoma (EAC) and squamous cell carcinoma (ESCC) follow divergent incidence trajectories in the United States. Rising use of electronic nicotine delivery systems (ENDS) and evolving demographic risk profiles may be resha...

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Article

928 Views

15 Pages

Impact of Hypoglycemia on Morbidity, Mortality, and Resource Utilization in Gastrointestinal Stromal Tumor: A Nationwide Analysis

Manasa Ginjupalli,
Jayalekshmi Jayakumar,
Arnold Forlemu,
Anuj Raj Sharma,
Praneeth Bandaru,
Vikash Kumar,
Kameswara Santosh Dheeraj Nalluri and
Madhavi Reddy

Gastroenterol. Insights2025, 16(4), 36;https://doi.org/10.3390/gastroent16040036

25 September 2025

Background: Non-islet cell tumor hypoglycemia is increasingly reported with gastrointestinal stromal tumors (GIST), but population-level estimates of its clinical impact are limited. We evaluated associations between hypoglycemia and inpatient outcom...

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