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Viruses, Volume 9, Issue 2

2017 February - 13 articles

Cover Story: With the initial discovery of a giant virus, mimivirus, the notion of viruses being small and simple was shattered. Since this discovery, there has been an increasing number of unique giant viruses isolated each year. Due to the sheer size, it is extremely challenging to obtain structural information on these giants. Here, we present a structural characterization of Samba Virus, a Mimivirus isolated from the Rio Negro in Brazil, combining data from cryo-EM, cryo-ET, SEM, and fluorescence microscopy. Also, we compare the morphology of Samba Virus and mimivirus virions. Read Full Article

Articles (13)

  • Article
  • Open Access
12 Citations
7,111 Views
15 Pages

Evaluation of Rice Resistance to Southern Rice Black-Streaked Dwarf Virus and Rice Ragged Stunt Virus through Combined Field Tests, Quantitative Real-Time PCR, and Proteome Analysis

  • Zhenchao Wang,
  • Lu Yu,
  • Linhong Jin,
  • Wenli Wang,
  • Qi Zhao,
  • Longlu Ran,
  • Xiangyang Li,
  • Zhuo Chen,
  • Rong Guo and
  • Baoan Song
  • + 4 authors

22 February 2017

Diseases caused by southern rice black-streaked dwarf virus (SRBSDV) and rice ragged stunt virus (RRSV) considerably decrease grain yield. Therefore, determining rice cultivars with high resistance to SRBSDV and RRSV is necessary. In this study, rice...

  • Article
  • Open Access
1 Citations
5,429 Views
12 Pages

21 February 2017

In the hydrodynamic injection (HI) BALB/c mouse model with the overlength viral genome, we have found that woodchuck hepatitis virus (WHV) could persist for a prolonged period of time (up to 45 weeks), while hepatitis B virus (HBV) was mostly cleared...

  • Article
  • Open Access
23 Citations
5,902 Views
10 Pages

A3R Phage and Staphylococcus aureus Lysate Do Not Induce Neutrophil Degranulation

  • Jan Borysowski,
  • Ryszard Międzybrodzki,
  • Piotr Wierzbicki,
  • Danuta Kłosowska,
  • Grażyna Korczak-Kowalska,
  • Beata Weber-Dąbrowska and
  • Andrzej Górski

21 February 2017

The objective of this study was to evaluate the effects of A3R phage and Staphylococcus aureus lysate obtained after phage infection on neutrophil degranulation. The exocytosis of primary and secondary granules from neutrophils was investigated in vi...

  • Review
  • Open Access
36 Citations
7,746 Views
15 Pages

Bat Astroviruses: Towards Understanding the Transmission Dynamics of a Neglected Virus Family

  • Kerstin Fischer,
  • Vinícius Pinho dos Reis and
  • Anne Balkema-Buschmann

21 February 2017

Bats belong to the order Chiroptera that represents the second largest order of mammals with more than 1200 species and an almost global distribution. Environmental changes and deforestation have severely influenced many ecosystems, intensifying the...

  • Article
  • Open Access
56 Citations
8,966 Views
15 Pages

Genetic Assessment of African Swine Fever Isolates Involved in Outbreaks in the Democratic Republic of Congo between 2005 and 2012 Reveals Co-Circulation of p72 Genotypes I, IX and XIV, Including 19 Variants

  • Leopold K. Mulumba–Mfumu,
  • Jenna E. Achenbach,
  • Matthew R. Mauldin,
  • Linda K. Dixon,
  • Curé Georges Tshilenge,
  • Etienne Thiry,
  • Noelia Moreno,
  • Esther Blanco,
  • Claude Saegerman and
  • Adama Diallo
  • + 1 author

18 February 2017

African swine fever (ASF) is a devastating disease of domestic pigs. It is a socioeconomically important disease, initially described from Kenya, but subsequently reported in most Sub-Saharan countries. ASF spread to Europe, South America and the Car...

  • Review
  • Open Access
165 Citations
15,940 Views
23 Pages

Epidemiology of Classic and Novel Human Astrovirus: Gastroenteritis and Beyond

  • Diem-Lan Vu,
  • Albert Bosch,
  • Rosa M. Pintó and
  • Susana Guix

18 February 2017

Since they were identified in 1975, human astroviruses have been considered one of the most important agents of viral acute gastroenteritis in children. However, highly divergent astroviruses infecting humans have been recently discovered and associa...

  • Review
  • Open Access
27 Citations
8,511 Views
15 Pages

HCIV-1 and Other Tailless Icosahedral Internal Membrane-Containing Viruses of the Family Sphaerolipoviridae

  • Tatiana A. Demina,
  • Maija K. Pietilä,
  • Julija Svirskaitė,
  • Janne J. Ravantti,
  • Nina S. Atanasova,
  • Dennis H. Bamford and
  • Hanna M. Oksanen

18 February 2017

Members of the virus family Sphaerolipoviridae include both archaeal viruses and bacteriophages that possess a tailless icosahedral capsid with an internal membrane. The genera Alpha- and Betasphaerolipovirus comprise viruses that infect halophilic e...

  • Article
  • Open Access
33 Citations
7,235 Views
13 Pages

Prevalence and Clinical Impact of Human Pegivirus-1 Infection in HIV-1-Infected Individuals in Yunnan, China

  • Zhijiang Miao,
  • Li Gao,
  • Yindi Song,
  • Ming Yang,
  • Mi Zhang,
  • Jincheng Lou,
  • Yue Zhao,
  • Xicheng Wang,
  • Yue Feng and
  • Xueshan Xia
  • + 1 author

15 February 2017

Human Pegivirus-1 (HPgV-1) may have a beneficial impact on disease progression in human immunodeficiency virus-1 (HIV-1) infection. However, analysis of the genotypic diversity of HPgV-1 and its relevance to the progression of HIV-1 disease remains l...

  • Article
  • Open Access
14 Citations
13,881 Views
16 Pages

Microscopic Characterization of the Brazilian Giant Samba Virus

  • Jason R. Schrad,
  • Eric J. Young,
  • Jônatas S. Abrahão,
  • Juliana R. Cortines and
  • Kristin N. Parent

14 February 2017

Prior to the discovery of the mimivirus in 2003, viruses were thought to be physically small and genetically simple. Mimivirus, with its ~750-nm particle size and its ~1.2-Mbp genome, shattered these notions and changed what it meant to be a virus. S...

  • Review
  • Open Access
66 Citations
8,342 Views
10 Pages

10 February 2017

Although a relatively recently emerged virus, identified only in 2004 as a separate species of avian astrovirus, chicken astrovirus (CAstV) has been associated with poor growth of broiler flocks, enteritis and diarrhea and is a candidate pathogen in...

  • Article
  • Open Access
11 Citations
5,853 Views
22 Pages

2 February 2017

Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells. MYXV is able to efficiently block all aspects of the type I interferon (IFN)‐induced...

  • Article
  • Open Access
10 Citations
9,567 Views
15 Pages

Echovirus 6 Infects Human Exocrine and Endocrine Pancreatic Cells and Induces Pro-Inflammatory Innate Immune Response

  • Luis Sarmiento,
  • Gun Frisk,
  • Mahesh Anagandula,
  • Monika Hodik,
  • Ilaria Barchetta,
  • Eitan Netanyah,
  • Eduardo Cabrera-Rode and
  • Corrado M. Cilio

30 January 2017

Human enteroviruses (HEV), especially coxsackievirus serotype B (CVB) and echovirus (E), have been associated with diseases of both the exocrine and endocrine pancreas, but so far evidence on HEV infection in human pancreas has been reported only in...

  • Article
  • Open Access
10 Citations
10,314 Views
15 Pages

The Characteristics of Herpes Simplex Virus Type 1 Infection in Rhesus Macaques and the Associated Pathological Features

  • Shengtao Fan,
  • Hongzhi Cai,
  • Xingli Xu,
  • Min Feng,
  • Lichun Wang,
  • Yun Liao,
  • Ying Zhang,
  • Zhanlong He,
  • Fengmei Yang and
  • Qihan Li
  • + 3 authors

30 January 2017

As one of the major pathogens for human herpetic diseases, herpes simplex virus type 1 (HSV1) causes herpes labialis, genital herpes and herpetic encephalitis. Our aim here was to investigate the infectious process of HSV1 in rhesus macaques and the...

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Viruses - ISSN 1999-4915