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Article

Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2

1
AgResearch Ltd., Hopkirk Research Institute, Massey University, Corner University Ave and Library Road, Palmerston North 4442, New Zealand
2
School of Veterinary Science, Massey University Manawatu (Turitea), Tennent Drive, Palmerston North 4474, New Zealand
3
New Zealand Food Safety Science and Research Centre, Massey University Manawatu (Turitea), Tennent Drive, Palmerston North 4474, New Zealand
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editors: Gregory Tannock and Hyunsuh Kim
Viruses 2021, 13(8), 1436; https://doi.org/10.3390/v13081436
Received: 23 June 2021 / Revised: 16 July 2021 / Accepted: 19 July 2021 / Published: 23 July 2021
(This article belongs to the Special Issue Strategies for Preventing Viral Epidemics and Pandemics)
Transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs through respiratory droplets passed directly from person to person or indirectly through fomites, such as common use surfaces or objects. The aim of this study was to determine the virucidal efficacy of blue LED (405 nm) and far-UVC (222 nm) light in comparison to standard UVC (254 nm) irradiation for the inactivation of feline infectious peritonitis virus (FIPV) on different matrices as a model for SARS-CoV-2. Wet or dried FIPV on stainless steel, plastic, or paper discs, in the presence or absence of artificial saliva, were exposed to various wavelengths of light for different time periods (1–90 min). Dual activity of blue LED and far-UVC lights were virucidal for most wet and dried FIPV within 4 to 16 min on all matrices. Individual action of blue LED and far-UVC lights were virucidal for wet FIPV but required longer irradiation times (8–90 min) to reach a 4-log reduction. In comparison, LED (265 nm) and germicidal UVC (254 nm) were virucidal on almost all matrices for both wet and dried FIPV within 1 min exposure. UVC was more effective for the disinfection of surfaces as compared to blue LED and far-UVC individually or together. However, dual action of blue LED and far-UVC was virucidal. This combination of lights could be used as a safer alternative to traditional UVC. View Full-Text
Keywords: 405 nm blue light; far-UVC; ultraviolet light; feline infectious peritonitis virus; viral inactivation; light disinfection; coronavirus; pandemic 405 nm blue light; far-UVC; ultraviolet light; feline infectious peritonitis virus; viral inactivation; light disinfection; coronavirus; pandemic
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MDPI and ACS Style

Gardner, A.; Ghosh, S.; Dunowska, M.; Brightwell, G. Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2. Viruses 2021, 13, 1436. https://doi.org/10.3390/v13081436

AMA Style

Gardner A, Ghosh S, Dunowska M, Brightwell G. Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2. Viruses. 2021; 13(8):1436. https://doi.org/10.3390/v13081436

Chicago/Turabian Style

Gardner, Amanda, Sayani Ghosh, Magdalena Dunowska, and Gale Brightwell. 2021. "Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2" Viruses 13, no. 8: 1436. https://doi.org/10.3390/v13081436

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