The First Co-Opted Endogenous Foamy Viruses and the Evolutionary History of Reptilian Foamy Viruses
Abstract
:1. Introduction
2. Materials and Methods
2.1. ERV-Spuma-Spu Mining
2.2. Consensus Sequence Reconstruction
2.3. EFVs in Other Reptiles
2.4. Recombination Analyses
2.5. Phylogenetic Analyses
2.6. Evolutionary Timescale Inference
3. Results
3.1. Characterisation of ERV-Spuma-Spu
3.2. The Discovery and Characterisation of Gecko EFVs
3.3. Recombination Analyses
4.4. Phylogenetic Analyses and Evolutionary Timescale Estimation
4. Discussion
Supplementary Materials
Author Contributions
Acknowledgments
Conflicts of Interest
References
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Protein | Best reciprocal BLASTp Hit | Accession Number | Query Coverage | E-Value | % Identity |
---|---|---|---|---|---|
Gag | Gag polyprotein [Feline foamy virus] | AAC58530.1 | 95% | 5 × 10−33 | 27% |
Pol | Pol [Rhesus macaque simian foamy virus] | YP_009513242.1 | 96% | 0.0 * | 44% |
Env | Env protein [Japanese macaque simian foamy virus] | YP_009508557.1 | 91% | 1 × 10−101 | 28% |
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Aiewsakun, P.; Simmonds, P.; Katzourakis, A. The First Co-Opted Endogenous Foamy Viruses and the Evolutionary History of Reptilian Foamy Viruses. Viruses 2019, 11, 641. https://doi.org/10.3390/v11070641
Aiewsakun P, Simmonds P, Katzourakis A. The First Co-Opted Endogenous Foamy Viruses and the Evolutionary History of Reptilian Foamy Viruses. Viruses. 2019; 11(7):641. https://doi.org/10.3390/v11070641
Chicago/Turabian StyleAiewsakun, Pakorn, Peter Simmonds, and Aris Katzourakis. 2019. "The First Co-Opted Endogenous Foamy Viruses and the Evolutionary History of Reptilian Foamy Viruses" Viruses 11, no. 7: 641. https://doi.org/10.3390/v11070641
APA StyleAiewsakun, P., Simmonds, P., & Katzourakis, A. (2019). The First Co-Opted Endogenous Foamy Viruses and the Evolutionary History of Reptilian Foamy Viruses. Viruses, 11(7), 641. https://doi.org/10.3390/v11070641