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17 November 2025

A Green-Synthesized Fluorescent Carbon Dot Probe Derived from Banana Peel for Cellular Imaging and Sensing of Tetracycline

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1
Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China
2
University Engineering Research Center of Watershed Protection and Green Development, Guilin University of Technology, Guilin 541006, China
3
Guangxi Key Laboratory of Calcium Carbonate Resources Comprehensive Utilization, College of Materials and Chemical Engineering, Hezhou University, Hezhou 542899, China
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Author to whom correspondence should be addressed.
Materials2025, 18(22), 5211;https://doi.org/10.3390/ma18225211 
(registering DOI)
This article belongs to the Topic Circular Materials Engineering: Waste Valorization and Sustainable Applications

Abstract

The valorization of biomass waste represents an important direction in green chemistry. This study successfully prepared blue fluorescent carbon dots (BP-CDs) from waste banana peels via a one-step hydrothermal method, establishing a dual-functional platform for both pollutant detection and cellular imaging. The resulting material exhibited uniform particle size (~2.05 nm), good water dispersibility, and strong fluorescence emission at 445 nm under 360 nm excitation. It maintained over 93% of its initial fluorescence intensity after 20 days, demonstrating excellent stability. Based on the inner filter effect, the probe enabled a highly selective detection of tetracycline with a detection limit of 0.191 µM and two wide linear ranges (0–15 µM, R2 = 0.996; 15–95 µM, R2 = 0.991). Cellular experiments confirmed the good biocompatibility of BP-CDs (cell viability > 84%) and their successful application in cell imaging. More importantly, the probe achieved visual observation and semi-quantitative analysis of the distribution and content of tetracycline in living cells, providing a direct tool for studying the cellular behavior of antibiotics. This work not only offers a new strategy for banana peel valorization but also develops a green fluorescence imaging platform suitable for tracking intracellular pollutants.

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