Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review
AbstractMarine natural products (MNPs) continue to be in the spotlight in the global drug discovery endeavor. Currently, more than 30,000 structurally diverse secondary metabolites from marine sources have been isolated, making MNPs a profound, renewable source to investigate novel drug compounds. Marine sponges of the genus Suberea (family: Aplysinellidae) are recognized as producers of bromotyrosine derivatives, which are considered distinct chemotaxonomic markers for the marine sponges belonging to the order Verongida. This class of compounds exhibits structural diversity, ranging from simple monomeric molecules to more complex molecular scaffolds, displaying a myriad of biological and pharmacological potentialities. In this review, a comprehensive literature survey covering the period of 1998–2018, focusing on the chemistry and biological/pharmacological activities of marine natural products from marine sponges of the genus Suberea, with special attention to the biogenesis of the different skeletons of halogenated compounds, is presented. View Full-Text
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El-Demerdash, A.; Atanasov, A.G.; Horbanczuk, O.K.; Tammam, M.A.; Abdel-Mogib, M.; Hooper, J.N.A.; Sekeroglu, N.; Al-Mourabit, A.; Kijjoa, A. Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review. Mar. Drugs 2019, 17, 115.
El-Demerdash A, Atanasov AG, Horbanczuk OK, Tammam MA, Abdel-Mogib M, Hooper JNA, Sekeroglu N, Al-Mourabit A, Kijjoa A. Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review. Marine Drugs. 2019; 17(2):115.Chicago/Turabian Style
El-Demerdash, Amr; Atanasov, Atanas G.; Horbanczuk, Olaf K.; Tammam, Mohamed A.; Abdel-Mogib, Mamdouh; Hooper, John N.A.; Sekeroglu, Nazim; Al-Mourabit, Ali; Kijjoa, Anake. 2019. "Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review." Mar. Drugs 17, no. 2: 115.
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