Association Between Radiological Stenosis Level and Patient-Reported Outcomes in Patients with Lumbar Spinal Stenosis: A Cross-Sectional Study
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Participants
2.3. Clinical Assessment
2.4. Bias
2.5. Sample Size
2.6. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
References
- Munakomi, S.; Cruz, R. Lumbar Spinal Stenosis. In StatPearls; StatPearls Publishing: Treasure Island, FL, USA, 2025. Available online: https://www.ncbi.nlm.nih.gov/books/NBK531493/ (accessed on 10 September 2025).
- Bagley, C.; MacAllister, M.; Dosselman, L.; Moreno, J.; Aoun, S.G.; El Ahmadieh, T.Y. Current concepts and recent advances in understanding and managing lumbar spine stenosis. F1000Research 2019, 8, 137. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Jenis, L.G.; An, H.S. Spine update. Lumbar foraminal stenosis. Spine 2000, 25, 389–394. [Google Scholar] [CrossRef] [PubMed]
- Buser, Z.; Ortega, B.; D’Oro, A.; Pannell, W.; Cohen, J.R.; Wang, J.; Golish, R.; Reed, M.; Wang, J.C. Spine Degenerative Conditions and Their Treatments: National Trends in the United States of America. Glob. Spine J. 2018, 8, 57–67. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Lee, G.Y.; Lee, J.W.; Choi, H.S.; Oh, K.J.; Kang, H.S. A new grading system of lumbar central canal stenosis on MRI: An easy and reliable method. Skelet. Radiol. 2011, 40, 1033–1039, Erratum in Skelet. Radiol. 2011, 40, 1127. PMID: 21286714. [Google Scholar] [CrossRef]
- Seo, J.; Lee, J.W. Magnetic Resonance Imaging Grading Systems for Central Canal and Neural Foraminal Stenoses of the Lumbar and Cervical Spines With a Focus on the Lee Grading System. Korean J. Radiol. 2023, 24, 224–234. [Google Scholar] [CrossRef]
- Fusini, F.; Girardo, M.; Aprato, A.; Massè, A.; Lorenzi, A.; Messina, D.; Colò, G. Percutaneous Cement Discoplasty in Degenerative Spinal Disease: Systematic Review of Indications, Clinical Outcomes, and Complications. World Neurosurg. 2022, 168, 219–226. [Google Scholar] [CrossRef] [PubMed]
- Garg, A.; Pathak, H.; Churyukanov, M.V.; Uppin, R.B.; Slobodin, T.M. Low back pain: Critical assessment of various scales. Eur. Spine J. 2020, 29, 503–518. [Google Scholar] [CrossRef] [PubMed]
- Duruöz, M.T.; Özcan, E.; Ketenci, A.; Karan, A. Development and validation of a functional disability index for chronic low back pain. J. Back. Musculoskelet. Rehabil. 2013, 26, 45–54. [Google Scholar] [CrossRef] [PubMed]
- Stucki, G.; Daltroy, L.; Liang, M.H.; Lipson, S.J.; Fossel, A.H.; Katz, J.N. Measurement properties of a self-administered outcome measure in lumbar spinal stenosis. Spine 1996, 21, 796–803. [Google Scholar] [CrossRef]
- Akgul, O.; Gulkesen, A.; Akgol, G.; Ozgocmen, S. MRdefined fat infiltration of the lumbar paravertebral muscles differs between non-radiographic axial spondyloarthritis and established ankylosing spondylitis. Mod. Rheumatol. 2013, 23, 811–816. [Google Scholar] [CrossRef] [PubMed]
- Stienen, M.N.; Maldaner, N.; Joswig, H.; Corniola, M.V.; Bellut, D.; Prömmel, P.; Regli, L.; Weyerbrock, A.; Schaller, K.; Gautschi, O.P. Objective functional assessment using the “Timed Up and Go” test in patients with lumbar spinal stenosis. Neurosurg. Focus. 2019, 46, E4. [Google Scholar] [CrossRef] [PubMed]
- Visual Analog Scale—An Overview | ScienceDirect Topics. Available online: https://www.sciencedirect.com/topics/medicine-and-dentistry/visual-analog-scale (accessed on 9 September 2025).
- Fairbank, J.C.; Pynsent, P.B. The Oswestry Disability Index. Spine 2000, 25, 2940–2952; discussion 2952. [Google Scholar] [CrossRef]
- Yakut, E.; Düger, T.; Öksüz, Ç.; Yörükan, S.; Üreten, K.; Turan, D.; Frat, T.; Kiraz, S.; Krd, N.; Kayhan, H.; et al. Validation of the Turkish Version of the Oswestry Disability Index for Patients With Low Back Pain. Spine 2004, 29, 581. [Google Scholar] [CrossRef]
- Çorbacıoğlu, Ş.K.; Aksel, G. Receiver operating characteristic curve analysis in diagnostic accuracy studies: A guide to interpreting the area under the curve value. Turk. J. Emerg. Med. 2023, 23, 195–198. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Munakomi, S.; Foris, L.A.; Varacallo, M.A. Spinal Stenosis and Neurogenic Claudication. In StatPearls; StatPearls Publishing: Treasure Island, FL, USA, 2025. Available online: https://www.ncbi.nlm.nih.gov/books/NBK430872/ (accessed on 15 December 2025).
- Tomkins, C.C.; Battié, M.C.; Rogers, T.; Jiang, H.; Petersen, S. A criterion measure of walking capacity in lumbar spinal stenosis and its comparison with a treadmill protocol. Spine 2009, 34, 2444–2449. [Google Scholar] [CrossRef] [PubMed]
- Tomkins-Lane, C.C.; Holz, S.C.; Yamakawa, K.S.; Phalke, V.V.; Quint, D.J.; Miner, J.; Haig, A.J. Predictors of walking performance and walking capacity in people with lumbar spinal stenosis, low back pain, and asymptomatic controls. Arch. Phys. Med. Rehabil. 2012, 93, 647–653. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Rodrigues Fernandes, R.; Urquhart, J.; Thatcher, M.; Bailey, C. Deterioration in clinical outcomes in patients with lumbar spinal stenosis 12-years following surgery. Spine J. 2025, in press. [Google Scholar] [CrossRef] [PubMed]
- Anderson, D.B.; Cheung, C.; Lane, C.; Melloh, M.; Dvorak, J.; Van Gelder, J.M.; Wong, A. Consensus on clinical outcome measures for lumbar spinal stenosis: Recommendations from the ISSLS lumbar spinal stenosis taskforce. Eur. Spine J. 2025, 34, 5725–5732. [Google Scholar] [CrossRef] [PubMed]
- Norisyam, Y.; Salim, A.A.; Bahrin, Z.; Yusof, M.I.; Paiman, M.; Nadarajan, C. Lateral Lumbar Spinal Stenosis: Associations With the Oswestry Disability Index, Visual Analogue Scale, and Magnetic Resonance Imaging. Cureus 2023, 15, e50475. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Splettstößer, A.; Khan, M.F.; Zimmermann, B.; Vogl, T.J.; Ackermann, H.; Middendorp, M.; Maataoui, A. Correlation of lumbar lateral recess stenosis in magnetic resonance imaging and clinical symptoms. World J. Radiol. 2017, 9, 223–229. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Arita, S.; Ishimoto, Y.; Hashizume, H.; Nagata, K.; Muraki, S.; Oka, H.; Takami, M.; Tsutsui, S.; Iwasaki, H.; Yukawa, Y.; et al. Is radiographic lumbar spinal stenosis associated with the quality of life? The Wakayama Spine Study. PLoS ONE 2022, 17, e0263930. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Caprariu, R.; Oprea, M.D.; Poenaru, D.V.; Andrei, D. Correlation between Preoperative MRI Parameters and Oswestry Disability Index in Patients with Lumbar Spinal Stenosis: A Retrospective Study. Medicina 2023, 59, 2000. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Sigmundsson, F.G.; Kang, X.P.; Jönsson, B.; Strömqvist, B. Correlation between disability and MRI findings in lumbar spinal stenosis: A prospective study of 109 patients operated on by decompression. Acta Orthop. 2011, 82, 204–210. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Fushimi, Y.; Otani, K.; Tominaga, R.; Nakamura, M.; Sekiguchi, M.; Konno, S.I. The association between clinical symptoms of lumbar spinal stenosis and MRI axial imaging findings. Fukushima J. Med. Sci. 2021, 67, 150–160. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Kuittinen, P.; Sipola, P.; Aalto, T.J.; Määttä, S.; Parviainen, A.; Saari, T.; Sinikallio, S.; Savolainen, S.; Turunen, V.; Kröger, H.; et al. Correlation of lateral stenosis in MRI with symptoms, walking capacity and EMG findings in patients with surgically confirmed lateral lumbar spinal canal stenosis. BMC Musculoskelet. Disord. 2014, 15, 247. [Google Scholar] [CrossRef]
- Sirvanci, M.; Bhatia, M.; Ganiyusufoglu, K.A.; Duran, C.; Tezer, M.; Ozturk, C.; Aydogan, M.; Hamzaoglu, A. Degenerative lumbar spinal stenosis: Correlation with Oswestry Disability Index and MR imaging. Eur. Spine J. 2008, 17, 679–685. [Google Scholar] [CrossRef]
- Yeung, C.M.; Heard, J.C.; Lee, Y.; Lambrechts, M.J.; Somers, S.; Singh, A.; Bloom, E.; D’Antonio, N.D.; Trenchfield, D.; Labarbiera, A.; et al. The Implication of Preoperative Central Stenosis on Patient-Reported Outcomes After Lumbar Decompression Surgery. World Neurosurg. 2023, 177, e300–e307. [Google Scholar] [CrossRef]
- Erçalık, T.; Atalay, K.G.; Toprak, C.Ş.; Gündüz, O.H. Outcome measurement in patients with low back pain undergoing epidural steroid injection. Turk. J. Phys. Med. Rehabil. 2019, 65, 154–159. [Google Scholar] [CrossRef] [PubMed]
- Tasdogan, A.M.; Kilic, E.T. Outcome Measurements for Pain Relief in Elderly Patients with Spinal Stenosis Undergoing Epidural Steroid Injection: Is Conservative Approach an Option? Turk. Neurosurg. 2020, 30, 734–738. [Google Scholar] [CrossRef] [PubMed]
- Karadağ, A.; Canbaş, M. Evaluation of the correlation between the Istanbul Low Back Pain Disability Index, Back Pain Functional Scale and other back pain disability scales in Turkish patients with low back pain. J. Back. Musculoskelet. Rehabil. 2022, 35, 771–775. [Google Scholar] [CrossRef] [PubMed]
- Pratt, R.K.; Fairbank, J.C.; Virr, A. The reliability of the Shuttle Walking Test, the Swiss Spinal Stenosis Questionnaire, the Oxford Spinal Stenosis Score, and the Oswestry Disability Index in the assessment of patients with lumbar spinal stenosis. Spine 2002, 27, 84–91. [Google Scholar] [CrossRef] [PubMed]
- Carlesso, C.; Piva, S.R.; Smith, C.; Ammendolia, C.; Schneider, M.J. Responsiveness of Outcome Measures in Nonsurgical Patients with Lumbar Spinal Stenosis: A Secondary Analysis From a Randomized Controlled Trial. Spine 2021, 46, 788–795. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]


| Non-LSS (n = 64) | LSS (n = 56) | p | ||
|---|---|---|---|---|
| Age (year) | Median (IQR) | 60.0 (IQR = 12.25) | 61.0 (IQR = 18.25) | 0.302 m |
| Gender: | ||||
| Female | n (%) | 50 (41.7%) | 44 (36.7%) | 0.953 x |
| Male | 14 (11.7%) | 12 (10.0%) | ||
| Occupation: | ||||
| Sedentary | n (%) | 56 (46.7%) | 47 (39.2%) | 0.325 x |
| Light/moderate | 8 (6.7%) | 8 (6.7%) | ||
| Heavy | 0 (0.0%) | 1 (0.8%) | ||
| Additional disease: | ||||
| Yes | n (%) | 35 (29.2%) | 29 (24.2%) | 0.751 x |
| Essential hypertension: | ||||
| Yes | n (%) | 27 (22.5%) | 25 (20.8%) | 0.787 x |
| Diabetes mellitus: | ||||
| Yes | n (%) | 13 (10.8%) | 8 (6.7%) | 0.386 x |
| Coronary artery disease: | ||||
| Yes | n (%) | 10 (8.3%) | 20 (8.3%) | 0.743 x |
| Cigarette usage: | ||||
| Yes | n (%) | 17 (14.2%) | 11 (9.2%) | 0.371 x |
| Duration of low back pain (months) | Median (IQR) | 24 (IQR = 36.0) | 18.0 (IQR = 42.0) | 0.187 m |
| Pain radiating to the lower extremities: | ||||
| Yes | n (%) | 39 (32.5%) | 43 (35.8%) | 0.063 x |
| Limited lumbar extension: | ||||
| Yes | n (%) | 28 (23.3%) | 38 (31.7%) | 0.008 x |
| Neurogenic claudication: | ||||
| Yes | n (%) | 10 (8.3%) | 18 (15.0%) | 0.033 x |
| Muscle weakness: | ||||
| Yes | n (%) | 7 (5.8%) | 10 (8.3%) | 0.278 x |
| Walking distance (m) | Median (IQR) | 500.0 (IQR = 400.0) | 450.0 (IQR = 425.0) | 0.024 x |
| Timed up and Go Test (s) | Median (IQR) | 10.0 (IQR = 3.0) | 11.5 (IQR = 5.25) | 0.023 x |
| Non-LSS (n = 64) | LSS (n = 56) | p | ||
|---|---|---|---|---|
| Lee grading system | ||||
| Grade 0 | 64 (53.3%) | - | ||
| Grade 1 | - | 24 (20.0%) | ||
| Grade 2 | - | 11 (9.2%) | ||
| Grade 3 | n (%) | - | 21 (17.5%) | - |
| Lee grading system | Median (IQR) | 0.0 (IQR = 0.0) | 2.0 (IQR = 2.0) | <0.001 m |
| Fatty degeneration of paravertebral muscle | ||||
| 0 | 10 (8.3%) | 11 (9.2%) | ||
| 1 | 13 (10.8%) | 15 (12.5%) | ||
| 2 | 15 (12.5%) | 10 (8.3%) | ||
| 3 | 12 (10.0%) | 16 (13.3%) | ||
| 4 | n (%) | 1 (0.8%) | 4 (3.3%) | - |
| Fatty degeneration of paravertebral muscle | Median (IQR) | 2.0 (IQR = 1.0) | 2.0 (IQR = 2.0) | 0.803 m |
| VAS | Median (IQR) | 4.0 (IQR = 2.0) | 6.0 (IQR = 3.0) | <0.001 m |
| ODI (score) | Median (IQR) | 30.0 (IQR = 20.5) | 38.0 (IQR = 18.5) | <0.001 m |
| ODI (%) | ||||
| 0–20% | 7 (5.8%) | 2 (1.7%) | ||
| 20–40% | 36 (30.0%) | 27 (22.5%) | ||
| 40–60% | 18 (15.0%) | 20 (16.7%) | ||
| 60–80% | 3 (2.5%) | 6 (5.0%) | ||
| 80–100% | n (%) | 0 (0.0%) | 1 (0.8%) | 0.033 m |
| ILBPDI | Median (IQR) | 31.5 (IQR = 13.25) | 41.0 (IQR = 15.25) | <0.001 m |
| SSS-Q total score | Median (IQR) | 19.0 (IQR = 7.0) | 30.0 (IQR = 14.0) | <0.001 m |
| SSS-Q Symptom severity score | Median (IQR) | 11.0 (IQR = 5.0) | 20.0 (IQR = 12.0) | <0.001 m |
| SSS-Q Symptom severity average | ||||
| 1–2 | 53 (44.2%) | 13 (10.8%) | ||
| 2.1–3 | 11 (9.2%) | 19 (15.8%) | ||
| 3.1–5 | n (%) | 0 (0.0%) | 24 (20.0%) | <0.001 m |
| SSS-Q Physical function score | Median (IQR) | 7.0 (IQR = 4.0) | 10.0 (IQR = 4.25) | <0.001 m |
| SSS-Q Physical function average | ||||
| 1–1.5 | 35 (29.2%) | 10 (8.3%) | ||
| 1.6–2.5 | 27 (22.5%) | 27 (22.5%) | ||
| 2.6–4 | n (%) | 2 (1.7%) | 19 (15.8%) | <0.001 m |
| Grade 1 LSS (n = 24) | Grade 2 LSS (n = 11) | Grade 3 LSS (n = 21) | p | ||
|---|---|---|---|---|---|
| VAS | Mean ± SD | 4.33 ± 1.58 | 5.91 ± 1.58 | 7.10 ± 1.45 | <0.001 a |
| ODI | Mean ± SD | 34.5 ± 13.35 | 38.23 ± 8.5 | 49.43 ± 13.51 | p = 0.001 k |
| ILBDI | Mean ± SD | 35.96 ± 12.52 | 41.0 ± 6.42 | 52.38 ± 13.81 | <0.001 a |
| SSS-Q total score | Mean ± SD | 25.08 ± 7.56 | 30.55 ± 7.22 | 38.57 ± 6.49 | <0.001 a |
| SSS-Q Symptom severity score | Mean ± SD | 16.29 ± 5.19 | 19.45 ± 4.7 | 25.61 ± 4.81 | <0.001 a |
| SSS-Q Physical function score | Mean ± SD | 8.79 ± 2.96 | 11.09 ± 1.92 | 12.95 ± 2.36 | <0.001 a |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Published by MDPI on behalf of the Lithuanian University of Health Sciences. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Çiftci İnceoğlu, S.; Ayyıldız, A.; Şahin, B.; Özcan, S.; İnceoğlu, A.; Ayyıldız, H.; Kuran, B. Association Between Radiological Stenosis Level and Patient-Reported Outcomes in Patients with Lumbar Spinal Stenosis: A Cross-Sectional Study. Medicina 2026, 62, 29. https://doi.org/10.3390/medicina62010029
Çiftci İnceoğlu S, Ayyıldız A, Şahin B, Özcan S, İnceoğlu A, Ayyıldız H, Kuran B. Association Between Radiological Stenosis Level and Patient-Reported Outcomes in Patients with Lumbar Spinal Stenosis: A Cross-Sectional Study. Medicina. 2026; 62(1):29. https://doi.org/10.3390/medicina62010029
Chicago/Turabian StyleÇiftci İnceoğlu, Selda, Aylin Ayyıldız, Bora Şahin, Sefa Özcan, Alperen İnceoğlu, Hakan Ayyıldız, and Banu Kuran. 2026. "Association Between Radiological Stenosis Level and Patient-Reported Outcomes in Patients with Lumbar Spinal Stenosis: A Cross-Sectional Study" Medicina 62, no. 1: 29. https://doi.org/10.3390/medicina62010029
APA StyleÇiftci İnceoğlu, S., Ayyıldız, A., Şahin, B., Özcan, S., İnceoğlu, A., Ayyıldız, H., & Kuran, B. (2026). Association Between Radiological Stenosis Level and Patient-Reported Outcomes in Patients with Lumbar Spinal Stenosis: A Cross-Sectional Study. Medicina, 62(1), 29. https://doi.org/10.3390/medicina62010029

