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Search Results (38,796)

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16 pages, 1087 KB  
Article
Age-Related Aesthetic Outcomes of Anterior Direct Composite Restorations: Color Match, Patient–Clinician Concordance, and Oral Health-Related Quality of Life
by Magda Mihaela Luca, Roxana Buzatu and Bogdan Andrei Bumbu
J. Clin. Med. 2026, 15(12), 4610; https://doi.org/10.3390/jcm15124610 (registering DOI) - 13 Jun 2026
Abstract
Background/Objectives: Anterior direct composite restorations are evaluated through instrumental color matching, clinician appraisal, and patient perception, but these endpoints may diverge by age. This cross-sectional study compared adolescents/young adults (AYA, 15–25 years) with adults/elderly (AE, 50–75 years) for spectrophotometric color difference (ΔE*ab), [...] Read more.
Background/Objectives: Anterior direct composite restorations are evaluated through instrumental color matching, clinician appraisal, and patient perception, but these endpoints may diverge by age. This cross-sectional study compared adolescents/young adults (AYA, 15–25 years) with adults/elderly (AE, 50–75 years) for spectrophotometric color difference (ΔE*ab), patient and clinician aesthetic ratings, patient–clinician agreement, and oral-health-related quality of life (OHRQoL). Methods: Consecutive recall patients with at least one anterior direct composite restoration placed ≥6 months earlier were screened; 128 were enrolled, and 126 completed all assessments (AYA n = 64; AE n = 62). Participants completed the OHIP-14 and aesthetic visual analogue scale (VAS) before receiving any USPHS, clinician VAS, or spectrophotometric feedback. A separate clinician, masked to patient scores and spectrophotometric outputs but not to patient age, recorded clinician VAS and modified USPHS criteria. Results: AE restorations showed higher ΔE*ab than AYA restorations (4.8 ± 1.6 vs. 3.2 ± 1.1; p < 0.001), whereas AYA reported lower patient VAS (72.4 ± 12.3 vs. 81.6 ± 10.8; p < 0.001) and higher OHIP-14 psychosocial burden (7.2 ± 2.8 vs. 4.0 ± 2.3; p < 0.001). Clinician VAS was higher in AYA (85.2 ± 7.3 vs. 79.4 ± 8.9; p < 0.001). Patient VAS correlated modestly with ΔE*ab (ρ = −0.38 in AYA; ρ = −0.31 in AE) and more strongly with psychosocial OHIP-14 scores (ρ = −0.54 and −0.47, respectively). Patient-clinician agreement was poor in AYA (ICC = 0.26) and moderate in AE (ICC = 0.58), with larger negative patient-minus-clinician discrepancies in AYA. Exploratory mediation statistically decomposed the age-related patient-satisfaction difference more through patient–clinician discrepancy than through ΔE*ab; causality cannot be inferred. Conclusions: Younger patients may experience dissatisfaction and psychosocial burden despite better instrumental color match. Assessment of anterior composites should combine objective shade measurement with patient-centered expectation clarification, and longitudinal studies should test temporal mechanisms and communication interventions. Full article
(This article belongs to the Special Issue Clinical Updates on Prosthodontics)
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26 pages, 1298 KB  
Article
Financial Knowledge or Managerial Competence? Disentangling Financial Literacy and Liquidity Constraints for Processing Continuity and Food Security in the Turkish Tea Industry
by Musa Gün and Mustafa Savcı
Foods 2026, 15(12), 2139; https://doi.org/10.3390/foods15122139 (registering DOI) - 13 Jun 2026
Abstract
The economic resilience of agricultural enterprises is increasingly relevant for maintaining processing continuity and food quality in highly perishable agro-food chains. This study examines the associations between financial knowledge, financial management competency, business liquidity, and operational food-processing continuity in Türkiye’s tea sector. A [...] Read more.
The economic resilience of agricultural enterprises is increasingly relevant for maintaining processing continuity and food quality in highly perishable agro-food chains. This study examines the associations between financial knowledge, financial management competency, business liquidity, and operational food-processing continuity in Türkiye’s tea sector. A quantitative cross-sectional design was employed, using structured survey data from 203 senior managers across 86 public and private tea-processing firms in Rize Province. The data were analysed using Ordinary Least Squares regression, mediation analysis, exploratory factor analysis, and robustness checks in accordance with OECD/INFE guidelines. Results indicate a significant deficit in theoretical financial knowledge (mean score: 4.47/10) alongside widespread overconfidence among 85% of managers. Applied financial management competency is positively associated with perceived business liquidity (β = 0.336, p < 0.001), suggesting that practical budgeting, cash-flow planning, and financial decision-making capabilities are relevant to maintaining operational funding capacity. In contrast, cash-flow difficulties are not significantly explained by firm-level financial knowledge, managerial competency, liquidity, or ownership structure (R2 = 0.014, p = 0.722), indicating that these difficulties may reflect broader seasonal and sector-wide financing constraints. The findings challenge the assumption of a linear relationship between theoretical financial knowledge and managerial outcomes. They suggest a dual policy approach that combines applied financial management training with structural financing mechanisms to ensure the continuity of fresh leaf procurement and processing. While the study does not directly measure food safety, post-harvest losses, or SDG outcomes, the results have potential implications for reducing processing disruptions and supporting more resilient agro-food processing systems. Full article
(This article belongs to the Section Food Security and Sustainability)
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30 pages, 13301 KB  
Article
Design and Field Demonstration of Compact, Low-Pressure, Clog-Resistant Drip Emitters
by Aditya Ghodgaonkar, Luis Niquet, Amanda L. Shorter, Arturo Lua, Charles Schmid, Dave Laybourn, Jeff Vildibill and Amos G. Winter V
Water 2026, 18(12), 1462; https://doi.org/10.3390/w18121462 (registering DOI) - 13 Jun 2026
Abstract
Compact low-pressure emitters (LPEs) can improve the affordability of drip irrigation, but they must also demonstrate clog resistance for long-term reliability and adoption. Recent research on LPEs has focused on their hydraulic modeling and characterization, but few studies have evaluated or improved their [...] Read more.
Compact low-pressure emitters (LPEs) can improve the affordability of drip irrigation, but they must also demonstrate clog resistance for long-term reliability and adoption. Recent research on LPEs has focused on their hydraulic modeling and characterization, but few studies have evaluated or improved their clog resistance. To address this gap, we present a design theory for clog-resistant LPEs and characterize their performance in the lab and field. We focused on the emitters’ weir (or ‘overflow groove’ or ‘channel’), a micrometer-scale internal hydraulic passage, traditionally having a rectangular cross-section. In LPEs, the weir must be shallow to generate the hydraulic resistance required for low-pressure operation, thereby increasing the risk of particulate-jamming-based clogging. A hydraulic model of weirs with arbitrary cross-sections was used to estimate that trapezoidal profiles could be 33–41% deeper than hydraulically equivalent rectangular ones, suggesting that the trade-off between clog resistance and hydraulic performance in LPEs could be navigated through weir cross-section design. To practically validate this proposition, two compact LPEs with trapezoidal weirs (1 and 2 L/h nominal discharge) were designed and tested in the lab and field. Lab results indicated compatibility with 125 μm (1 L/h) and 177 μm (2 L/h) mesh filters that are typical for these flow rates, providing a basis for field testing the LPEs against commercial emitters. After field tests with these filters, the LPEs held 90–94% of their initial discharge and demonstrated irrigation reliability that was statistically on par with or better than some commercial emitters, despite having 15–65% lower operating pressure. The findings of this work demonstrate the practical viability of compact LPEs for affordable drip irrigation and provide a design framework for their continued development. Full article
(This article belongs to the Section Hydraulics and Hydrodynamics)
20 pages, 1613 KB  
Article
Rheological Transformation of Waxy Crude Oil During Transition to a Viscoplastic State
by Uzak Zhapbasbayev, Timur Bekibayev, Gaukhar Ramazanova and Olzhas Kenzhaliev
Appl. Sci. 2026, 16(12), 5999; https://doi.org/10.3390/app16125999 (registering DOI) - 13 Jun 2026
Abstract
This study investigates non-isothermal laminar flow of waxy crude oil in a pipe. Due to heat exchange with the surroundings, the flow cools along the pipe length, resulting in a gradual transformation of the oil rheology from Newtonian to viscoplastic behavior. The mathematical [...] Read more.
This study investigates non-isothermal laminar flow of waxy crude oil in a pipe. Due to heat exchange with the surroundings, the flow cools along the pipe length, resulting in a gradual transformation of the oil rheology from Newtonian to viscoplastic behavior. The mathematical model is based on the generalized Navier–Stokes equations coupled with the Shvedov–Bingham rheological model and the effective viscosity approach. The governing equations were solved numerically using the control volume method in the velocity–pressure formulation. The numerical simulations produced velocity, temperature, and effective viscosity fields, as well as pressure-drop data characterizing the rheological state of the waxy crude oil throughout the pipe flow domain. It was established that, in the central region of the inlet flow, the oil retains Newtonian behavior, whereas viscoplastic behavior begins to develop near the pipe wall. Further downstream, the flow progressively transforms into a viscoplastic state over the entire pipe cross-section, accompanied by the formation of stagnant near-wall regions and a plug-flow core. Full article
19 pages, 633 KB  
Article
Teleophthalmology and Teleglaucoma in Clinical Practice: Attitudes of Ophthalmologists in Bulgaria
by Stanka Uzunova, Rumyana Stoyanova, Marin Atanassov, Angel Atanasov and Kristina Kilova
Healthcare 2026, 14(12), 1696; https://doi.org/10.3390/healthcare14121696 (registering DOI) - 13 Jun 2026
Abstract
Background: Over the past two decades, teleophthalmology has become an effective approach for glaucoma screening and follow-up, with its adoption markedly accelerated by the COVID-19 pandemic. Objectives: The aim of the present study was to explore and analyze the attitudes of ophthalmologists in [...] Read more.
Background: Over the past two decades, teleophthalmology has become an effective approach for glaucoma screening and follow-up, with its adoption markedly accelerated by the COVID-19 pandemic. Objectives: The aim of the present study was to explore and analyze the attitudes of ophthalmologists in Bulgaria toward the application of teleglaucoma, digital communication, and artificial intelligence in clinical practice. Methods: A cross-sectional survey study was conducted among 113 ophthalmologists between September 2024 and March 2025, representing 10.5% of all licensed ophthalmologists in Bulgaria (n = 1074). Results: Age, professional experience, and specialization influenced the level of involvement in managing glaucoma patients. The level of awareness regarding the term ‘teleophthalmology’ was higher among respondents with a specialization in ophthalmology and those holding a doctoral degree (p = 0.001). Among the ophthalmologists surveyed, 35.4% (n = 40) provided teleophthalmology services, while an additional 19.5% (n = 22) reported no prior provision of such services but planned to do so in the future. The most preferred method for conducting teleophthalmology consultations was telephone communication (n = 27; 67.5%), followed by communication via Skype, Viber, or Messenger (n = 23; 57.5%). Physicians with longer professional experience more frequently conducted remote consultations with patients they already knew (p = 0.006). A substantial proportion of respondents (85.0%, n = 96) expressed willingness to participate in training related to contemporary trends and the provision of remote medical services. More than half of respondents expressed positive attitudes toward the use of artificial intelligence in ophthalmology, although practical implementation remained limited. Conclusions: The present study outlined the current landscape of attitudes among ophthalmologists in Bulgaria toward teleglaucoma, digital communication, and the use of artificial intelligence in clinical practice. The findings indicated a moderately positive yet cautious stance—remote services were perceived primarily as complementary tools, particularly for the follow-up of previously known patients and for real-time collaboration between specialists. Full article
(This article belongs to the Section Digital Health Technologies)
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16 pages, 634 KB  
Article
Association Between Electronic Device Usage, Physical Activity, and Sleep Quality Related to Cervicogenic Headache Among College Students in Saudi Arabia
by Shahul Hameed Pakkir Mohamed, Abdulaziz A. Albalwi, Mohamed Taher Mahmoud Eldesoky, Hamad S. Al Amer, Ahmad A. Alharbi, Jana Alhmeed, Emtenan Alhakami, Shahad Battal Alanazi, Maha Alrashedi and Ghala Dakhilallah
Healthcare 2026, 14(12), 1695; https://doi.org/10.3390/healthcare14121695 (registering DOI) - 13 Jun 2026
Abstract
Background and Objectives: Cervicogenic headaches (CGH) are increasingly common among college students and may negatively affect academic performance and sleep quality. This study aimed to identify the self-reported prevalence of cervicogenic-type head and neck pain in a convenience sample of Saudi college students [...] Read more.
Background and Objectives: Cervicogenic headaches (CGH) are increasingly common among college students and may negatively affect academic performance and sleep quality. This study aimed to identify the self-reported prevalence of cervicogenic-type head and neck pain in a convenience sample of Saudi college students and to examine its associations with electronic device use, physical activity, and sleep quality among college students in Saudi Arabia. Materials and Methods: A cross-sectional study was conducted among 313 college students from various Saudi university colleges using an online self-administered questionnaire. The questionnaire gathered information on sociodemographic characteristics, electronic device usage, neck pain awareness, physical activity levels, and sleep quality. Descriptive statistics were used to summarize the data, and chi-square tests were used to explore associations between potential predictors and the prevalence of self-reported cervicogenic-type head and neck pain consistent with possible CGH. Results: Most participants were female (84.3%) and aged 18–25 years (95.2%). Cervicogenic-type head and neck pain were reported by 65.2% (n = 204/313), while 56.5% experienced moderate to severe stress. A significant association was found with perceived stress (p = 0.002). Prolonged electronic device use (>4 h/day: 77.9%; p < 0.01), lower physical activity (p = 0.056), medication use (p < 0.01), headache exacerbation with inactivity (p = 0.006), and poor sleep quality (95.1% with PSQI > 10; p = 0.044) were significantly associated. Conclusions: These findings highlight associations between excessive electronic device use, low physical activity, and poor sleep quality with self-reported cervicogenic-type head and neck pain among Saudi college students. Future longitudinal studies and randomized controlled trials are needed to determine whether targeting these factors reduces the prevalence of CGH. Full article
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16 pages, 1453 KB  
Article
Between Aesthetics and Health: Disordered Eating, Exercise Addiction, and Body Image in Competitive Bodybuilders
by Federica Moro, Irene Cruccolini, Mario Mauro, Natascia Rinaldo, Emanuela Gualdi-Russo, Luciana Zaccagni and Stefania Toselli
J. Funct. Morphol. Kinesiol. 2026, 11(2), 236; https://doi.org/10.3390/jfmk11020236 (registering DOI) - 13 Jun 2026
Abstract
Objectives: To examine disordered eating behaviors, orthorexic tendencies, binge-eating episodes, attitudes toward exercise, perceived hormone-related symptoms and body image perception among competitive bodybuilders across different levels of competitive experience. Methods: In this cross-sectional study, 60 competitive bodybuilders (29 men, 31 women) [...] Read more.
Objectives: To examine disordered eating behaviors, orthorexic tendencies, binge-eating episodes, attitudes toward exercise, perceived hormone-related symptoms and body image perception among competitive bodybuilders across different levels of competitive experience. Methods: In this cross-sectional study, 60 competitive bodybuilders (29 men, 31 women) completed an anonymous online questionnaire. The survey evaluated demographic characteristics, coaching and training management, phase-specific symptoms (such as libido, sleep, eating behaviors, and menstrual alterations), orthorexic tendencies, exercise addiction, and body-image perception. Results: Both sexes reported reduced libido, increased hunger, and sleep disturbances, along with frequent weight monitoring and common binge-eating episodes. Moreover, females frequently reported menstrual irregularities. ORTO-15 scores indicated a potential risk of orthorexia nervosa, while EAI-3 scores suggested a risk of exercise addiction in novice females and advanced males, with differences in mood regulation and guilt across sex and experience. Males showed higher perceived and ideal muscle mass, whereas females reported higher perceived body fat and a preference for leaner physiques. Conclusions: Competitive bodybuilders of both sexes exhibit post-competition binge eating, mood- and appearance-driven exercise behaviors, and pronounced body-image concerns. Screening, education on energy availability, structured post-competition support, and health-focused coaching are recommended to prevent the progression from sport-specific practices to clinical pathology. Full article
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12 pages, 393 KB  
Article
Years of Experience and Its Association with Indicators of Adiposity and Health-Related Quality of Life in Teachers: A Cross-Sectional Study
by Andrés Godoy-Cumillaf, Josivaldo de Souza-Lima, Maribel Parra-Saldias, Daniel Duclos-Bastias, Claudio Farias-Valenzuela, Eugenio Merellano-Navarro and José Bruneau-Chávez
Healthcare 2026, 14(12), 1694; https://doi.org/10.3390/healthcare14121694 (registering DOI) - 13 Jun 2026
Abstract
Background/Objectives: Teachers in educational institutions are continuously exposed to high occupational demands, which may contribute to the development of increased adiposity and comparatively unfavorable health-related quality of life (HRQoL) scores. However, there is limited evidence regarding how years of professional experience is [...] Read more.
Background/Objectives: Teachers in educational institutions are continuously exposed to high occupational demands, which may contribute to the development of increased adiposity and comparatively unfavorable health-related quality of life (HRQoL) scores. However, there is limited evidence regarding how years of professional experience is associated with these indicators in teachers. The objective of this study is to examine the association between years of professional experience, adiposity indicators, and HRQoL among teachers in educational institutions. Methods: An observational, relational, exploratory cross-sectional study was conducted in 175 teachers from educational institutions in the city of Temuco, Chile. Body mass index (BMI), waist-to-height ratio (WHtR), and waist-to-hip ratio (WHR) were assessed as adiposity indicators, and health-related quality of life (HRQoL) was measured using the SF-12. Age, sex, and years of professional experience were recorded. Simple and multivariable linear regression models were used to analyze the association between years of experience and the study variables, adjusting for age and sex. Additionally, experience tertiles were compared using ANOVA and ANCOVA. Results: In the unadjusted analyses, greater years of professional experience were associated with higher adiposity indicators, including BMI (β = 0.071; 95% CI: 0.020 to 0.129). However, after adjustment for age and sex, these associations were attenuated and no longer statistically significant (adjusted BMI: β = −0.172; 95% CI: −0.434 to 0.053). Associations with PCS and MCS scores were also not statistically significant after adjustment. Conclusions: Teachers exhibited high levels of adiposity and HRQoL scores suggesting an unfavorable perceived health profile. The observed associations between years of professional experience and adiposity or HRQoL appear to be largely explained by age rather than by professional experience itself. Future longitudinal studies are needed to more precisely distinguish between the effects of aging and prolonged occupational exposure. However, the findings should be interpreted cautiously given the convenience sampling design and the inclusion of teachers from a single city. Full article
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18 pages, 5579 KB  
Article
Research on the Absorption Properties of Fe70Ni30 Alloy/SiO2 Coated Continuous Glass Fiber Composites by Magnetron Sputtering
by Zhuohui Zhou, Mengyu Zhou, Zhiyong Wang and Yan Zhao
Materials 2026, 19(12), 2552; https://doi.org/10.3390/ma19122552 (registering DOI) - 12 Jun 2026
Abstract
In this study, Fe70Ni30 metal was deposited onto continuous glass fiber composites via magnetron sputtering, followed by surface coating with SiO2. The effects of key process parameters-including Fe70Ni30 sputtering duration (2, 5, 10, 20, and [...] Read more.
In this study, Fe70Ni30 metal was deposited onto continuous glass fiber composites via magnetron sputtering, followed by surface coating with SiO2. The effects of key process parameters-including Fe70Ni30 sputtering duration (2, 5, 10, 20, and 30 min) and SiO2 surface coating-on the electromagnetic properties and microwave absorption performance of the materials were systematically investigated. Scanning electron microscopy (SEM) characterization revealed that as sputtering time increased, the metal coating evolved from discrete small particles into a continuous film. Cross-sectional SEM analysis further demonstrated the formation of a bilayer structure after SiO2 introduction. X-ray diffraction (XRD) patterns confirmed the presence of diffraction peaks corresponding to the Fe70Ni30 alloy solid solution. Electromagnetic parameter measurements indicated that the influence of sputtering time on electromagnetic properties was primarily pronounced during the metal layer growth stage; once a continuous film was formed, the variation in electromagnetic parameters diminished. Concurrently, the SiO2 coating exhibited a significant regulatory effect on dielectric parameters. Reflection coefficient calculations showed that the optimal absorption thickness for the single-layer material ranged from 2.5 to 3.0 mm, with the absorption peak shifting toward lower frequencies as thickness increased. However, the effective absorption bandwidth (EAB) was only 3–5 GHz, failing to meet wideband requirements. In contrast, the three-layer composite structure (total thickness: 3.8 mm) optimized via genetic algorithm achieved impedance gradient and loss synergy, expanding the EBW (R < −10 dB) from 4.8 GHz (single layer) to 10 GHz (8–18.0 GHz)-a substantial improvement over the single-layer configuration. This work provides experimental evidence and technical support for the structural design and process optimization of lightweight, high-efficiency, wideband microwave-absorbing materials. Full article
(This article belongs to the Topic Advanced Composite Materials)
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19 pages, 846 KB  
Article
Clinical Determinants of Halitosis in Elderly Patients with Complete, Partial, and Fixed Prosthetic Rehabilitation
by Romina Georgiana Bita, Otilia Cornelia Boloș, Edida Maghet, Adrian Boloș, Raluca Briceag and Bogdan Andrei Bumbu
J. Clin. Med. 2026, 15(12), 4590; https://doi.org/10.3390/jcm15124590 (registering DOI) - 12 Jun 2026
Abstract
Background/Objectives: Halitosis in geriatric patients is multifactorial, but the joint contribution of prosthetic rehabilitation type and polypharmacy after routine dental procedures has rarely been quantified. We investigated how prosthesis type, polypharmacy, and salivary function were associated with volatile sulfur compound (VSC) burden [...] Read more.
Background/Objectives: Halitosis in geriatric patients is multifactorial, but the joint contribution of prosthetic rehabilitation type and polypharmacy after routine dental procedures has rarely been quantified. We investigated how prosthesis type, polypharmacy, and salivary function were associated with volatile sulfur compound (VSC) burden and self-perceived halitosis in elderly dental patients. Methods: This cross-sectional study enrolled 88 patients aged ≥65 years, four weeks after completing routine dental procedures. Participants were stratified into three groups: complete denture wearers (n = 30), partial removable denture wearers (n = 28), and fixed prostheses/implants (n = 30). We measured unstimulated salivary flow rate (uSFR), tongue coating index (TCI), denture biofilm index, total VSCs (Halimeter®), organoleptic score (0–5), and self-perceived halitosis. Polypharmacy, comorbidities, and the Geriatric Oral Health Assessment Index (GOHAI) were recorded. Analyses included one- and two-way ANOVA, Spearman correlations, theory-informed multivariable linear and logistic regression, exploratory mediation analysis, and ROC curves. Results: Forty-two participants (47.7%) reported halitosis. Mean VSC differed across groups (complete dentures 278.2 ± 38.6 ppb; partial 211.2 ± 46.3 ppb; fixed 164.4 ± 43.9 ppb; ANOVA p < 0.001). uSFR correlated inversely with VSC (ρ = −0.61, p < 0.001) and TCI correlated positively (ρ = 0.56, p < 0.001). A significant prosthesis × polypharmacy interaction was observed (F = 3.74, p = 0.029, η2p = 0.082): polypharmacy was associated with higher VSC most clearly among partial and fixed prostheses wearers, whereas complete denture wearers showed high VSC levels regardless of polypharmacy status. Exploratory mediation findings were consistent with partial indirect association, with 45.9% of the polypharmacy–VSC association statistically explained by reduced uSFR; however, the cross-sectional design precludes causal or temporal interpretation. The full multivariable model showed apparent discrimination for self-perceived halitosis (AUC = 0.92), while the simplified four-item chairside composite model showed AUC = 0.89; neither estimate was optimism-corrected or externally validated. Conclusions: In elderly post-procedure patients, complete denture wearing, polypharmacy, and salivary hypofunction were independently and jointly associated with higher halitosis burden. Reduced salivary flow was consistent with a partial indirect statistical pathway in the polypharmacy–VSC association, supporting hydration counseling and meticulous prosthesis hygiene as low-cost geriatric interventions. Sensitivity analyses excluding implant-supported restorations, participants with MMSE scores of 24–26, and expanded mediation models including TCI and biofilm/plaque did not materially change the main inference. Full article
(This article belongs to the Special Issue Clinical Updates on Prosthodontics)
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17 pages, 921 KB  
Article
The Societal Burden of Breast Cancer in Working-Age Women in Croatia: A Multicentre Cross-Sectional Study
by Vid Duplančić, Ana Bobinac, Luka Vončina, Katarina Hraste, Ana Tečić Vuger, Robert Šeparović and Eduard Vrdoljak
Healthcare 2026, 14(12), 1693; https://doi.org/10.3390/healthcare14121693 (registering DOI) - 12 Jun 2026
Abstract
Background/Objectives: Breast cancer affects working-age women not only through treatment and survival but also through health-related quality of life (HRQoL), work capacity and informal caregiving needs. Evidence from Central and Eastern Europe remains limited. This study estimated the indirect societal burden of breast [...] Read more.
Background/Objectives: Breast cancer affects working-age women not only through treatment and survival but also through health-related quality of life (HRQoL), work capacity and informal caregiving needs. Evidence from Central and Eastern Europe remains limited. This study estimated the indirect societal burden of breast cancer among working-age women in Croatia and reported economic indirect costs separately from monetised HRQoL/welfare loss. Methods: A multicentre cross-sectional study conducted in 2024 included women aged 18–65 years receiving outpatient oncology care at two tertiary centres in Croatia. HRQoL was assessed with the EuroQol five-dimension five-level instrument (EQ-5D-5L) and compared with Croatian general-population norms. Utility decrements were annualised and monetised using a national willingness-to-pay threshold of €17,000 per quality-adjusted life year (QALY). Work productivity impairment was measured using the Work Productivity and Activity Impairment: General Health (WPAI:GH) questionnaire and valued, together with informal care, using the human-capital approach. Deterministic sensitivity analyses and approximate 95% confidence intervals were used to show how the estimates changed under key assumptions. Results: A total of 271 women participated (mean age 51.3 years among age-eligible records). Mean EQ-5D-5L utility was 0.76 versus 0.91 in the general population, corresponding to an annual QALY loss of 0.15 and a monetised HRQoL/welfare loss of €2550 per patient-year (95% CI €2083–€3017). Among employed participants, mean overall work productivity loss was 43.9% (842.9 h/year), equivalent to €7333 annually (95% CI €6311–€8355). Informal caregiving was reported by 54.7% of participants, with mean annual costs of €1566 (95% CI €1269–€1863). Economic indirect costs were €8899 per patient-year (95% CI €7835–€9963). In an extended welfare-inclusive scenario, the estimated burden was €11,449 per patient-year (95% CI €10,287–€12,611), corresponding to an illustrative national estimate of €86 million (95% CI €77–€95 million; 0.11% of gross domestic product). Conclusions: Breast cancer in working-age women imposes a substantial societal burden in Croatia, driven by reduced HRQoL, productivity losses and informal caregiving needs. These findings support taking societal burden into account in public health planning, survivorship care and health policy decision-making. Full article
(This article belongs to the Section Public Health and Preventive Medicine)
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20 pages, 431 KB  
Article
Experiential and Financial Factors Associated with Metaverse Readiness: Evidence from Lebanon
by Nada Mallah Boustani
Adm. Sci. 2026, 16(6), 283; https://doi.org/10.3390/admsci16060283 (registering DOI) - 12 Jun 2026
Abstract
This study examines experiential and financial factors associated with Metaverse readiness in Lebanon. Drawing on a socio-technical readiness perspective informed by selected concepts from technology adoption literature, the study explores how interest in immersive technologies, remote work experience, and perceived financial security in [...] Read more.
This study examines experiential and financial factors associated with Metaverse readiness in Lebanon. Drawing on a socio-technical readiness perspective informed by selected concepts from technology adoption literature, the study explores how interest in immersive technologies, remote work experience, and perceived financial security in decentralized digital assets relate to individual readiness and perceived organizational expectations. Using an exploratory cross-sectional survey of 231 respondents, multiple regression analyses were conducted to examine these associations. The findings indicate that interest in VR/AR technologies and positive remote work experience are positively associated with individual willingness to use the Metaverse for work, education, or professional activities. Perceived financial security in decentralized digital assets is also positively associated with perceived organizational benefit expectations. The results suggest that Metaverse readiness is linked not only to technological interest but also to prior digital collaboration experience and financial trust. By focusing on Lebanon as a developing and crisis-affected economy, the study contributes a context-sensitive and perception-based understanding of readiness for immersive digital ecosystems. Practical implications are discussed for organizations and policymakers seeking to support responsible digital transformation. Full article
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16 pages, 302 KB  
Article
Self-Reported Depressive Symptomatology Among University Students: Evidence from the PROTEGER-SE Project
by Karine Santana de Azevedo Zago, Raissa Pereira Dutra, Clesnan Mendes-Rodrigues, Amanda Viana Hortêncio, Analicy Rodrigues Xavier, Sarah Campos Moura Rabelo, Gustavo Henrique Borges de Souza, Felipe Rodrigues Torres, Polyana Alvarenga Matumoto, Mônica Rodrigues da Silva, Hélder Eterno da Silveira, Elaine Saraiva Calderari, Tiago Rocha Pinto, Ricardo Wagner Machado da Silveira, Cynthia Daniela Figueiredo de Souza, Tatiana Benevides Magalhães Braga, Marciana Gonçalves Farinha, Luiza Pereira Silva Assis, Beatriz da Silva Vieira and Fabiola Alves Gomes
Psychiatry Int. 2026, 7(3), 136; https://doi.org/10.3390/psychiatryint7030136 (registering DOI) - 12 Jun 2026
Abstract
This study aimed to assess the self-reported depressive symptomatology of university students during their first therapeutic online consultation and intervention at PROTEGER-SE Project, using the Patient Health Questionnaire-9 (PHQ-9) as a screening instrument. A cross-sectional, retrospective, and analytical study was conducted with 350 [...] Read more.
This study aimed to assess the self-reported depressive symptomatology of university students during their first therapeutic online consultation and intervention at PROTEGER-SE Project, using the Patient Health Questionnaire-9 (PHQ-9) as a screening instrument. A cross-sectional, retrospective, and analytical study was conducted with 350 records of university students from 2020–2023 collected immediately after their first appointment. Many students presented moderate to severe depressive symptoms, with one-third classified as severe. Logistic regression showed that female sex was associated with higher symptomatology severity, while lower PHQ-9 scores and Humanities field of study enrollment predicted perceived improvement after consultation. Findings reinforce the importance of university-based mental health support, gender-sensitive approaches, and the systematic use of PHQ-9 for early screening and continuous monitoring. Full article
26 pages, 42232 KB  
Article
Influence of Tectonic Activity Characteristics of the Permian–Triassic and Jurassic on Oil and Gas Migration Efficiency in the Luzhou Area—A Case Study of Fault Characteristics
by Yuehong Yang, Saijun Wu, Tao Li, Yanxi Li, Jiachang Zhang, Yan Sun and Yanbo Xiao
Appl. Sci. 2026, 16(12), 5977; https://doi.org/10.3390/app16125977 (registering DOI) - 12 Jun 2026
Abstract
In order to clarify the controlling effects of tectonic activity on hydrocarbon migration efficiency in the Permian–Triassic strata of the Luzhou area, Sichuan Basin, this study takes faults as the research objective. Using 3D seismic data, tectonic evolution records, and single-well test data, [...] Read more.
In order to clarify the controlling effects of tectonic activity on hydrocarbon migration efficiency in the Permian–Triassic strata of the Luzhou area, Sichuan Basin, this study takes faults as the research objective. Using 3D seismic data, tectonic evolution records, and single-well test data, we systematically analyze the geometric characteristics, activity phases, classification by grade and type, and reservoir-controlling effects of faults. The results show that a total of 843 reverse faults have been identified in the study area. The major faults are distributed in a NE-SW trend, with eight planar combination styles developed, and the main cross-sectional styles are back-thrust and “Y”-shaped types. The faults experienced four phases of tectonic activity: Caledonian, Hercynian, Indosinian, and Yanshan–Himalayan. Among these, the Indosinian phase is the key formative phase, effectively connecting the source rocks and reservoirs. The faults are classified into three grades and four categories: source-connected faults, reservoir-modifying faults, damaging faults, and source-connected and damaging faults. Migration efficiency is jointly controlled by fault grade, activity phases, and the penetrated formations. Among them, third-order source-connected faults formed during the Indosinian phase exhibit the highest migration efficiency, while first-order damaging faults formed during the Yanshan phase tend to cause hydrocarbon dissipation. This study can provide a reference for hydrocarbon exploration and the prediction of favorable areas in the Luzhou area. Full article
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11 pages, 749 KB  
Article
Regional Analysis of the Structural Availability of Physical and Rehabilitation Medicine Services Funded by the National Health Insurance Fund for Patients with Rare Diseases in Bulgaria
by Evelina Razheva, Georgi Iskrov, Tsonka Miteva-Katrandzhieva and Rumen Stefanov
Healthcare 2026, 14(12), 1691; https://doi.org/10.3390/healthcare14121691 (registering DOI) - 12 Jun 2026
Abstract
Background: Rare diseases are associated with chronic progression, functional impairment, and complex care needs, requiring long-term and coordinated rehabilitation. Physical and Rehabilitation Medicine (PRM) plays a key role in maintaining functional capacity and improving quality of life; however, access to rehabilitation services remains [...] Read more.
Background: Rare diseases are associated with chronic progression, functional impairment, and complex care needs, requiring long-term and coordinated rehabilitation. Physical and Rehabilitation Medicine (PRM) plays a key role in maintaining functional capacity and improving quality of life; however, access to rehabilitation services remains uneven across regions. Aim: This study aims to assess the regional structural availability of PRM services across Bulgaria and to identify territorial differences in the organizational profile of rehabilitation services that may influence the potential availability of rehabilitation care for patients with rare diseases. Methods: A descriptive cross-sectional study was conducted using publicly available aggregated data from the NHIF and the National Statistical Institute as of 31 December 2024. Structural indicators included the number of outpatient and inpatient PRM healthcare facilities and PRM specialists, standardized per 100,000 population, as well as the outpatient-to-inpatient facility ratio (OFs/IFs). Hierarchical cluster analysis (Ward’s method, Euclidean distance) was applied as an exploratory tool to identify similarities in regional service availability profiles. Results: Substantial regional differences in the structural availability of PRM services were identified. Outpatient facilities ranged from 4.46 to 6.74 per 100,000 population, while inpatient facilities ranged from 2.30 to 3.42 per 100,000 population. The OFs/IFs ratio varied between 1.30 and 2.26, indicating different organizational profiles of PRM service provision. Exploratory hierarchical clustering suggested two broad regional service profiles: one characterized by a relatively balanced distribution of outpatient and inpatient structures and another characterized by a predominance of outpatient-oriented rehabilitation services. Conclusion: The findings reveal substantial regional differences in the organization of PRM services in Bulgaria. Regions with a predominance of outpatient structures may demonstrate different capacities for delivering comprehensive rehabilitation services, particularly for patients with complex long-term needs, including rare diseases. The results highlight the need for targeted regional planning, improved integration of rehabilitation services, and policy measures aimed at ensuring equitable access to care. Full article
(This article belongs to the Special Issue Physiotherapy and Physical Therapy in Modern Rehabilitation)
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