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Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.

Current Issues in Molecular Biology, Volume 28, Issue 1

October 2018 - 4 articles

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Articles (4)

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Review

45 Citations

2,936 Views

22 Pages

A Review of CRISPR-Based Genome Editing: Survival, Evolution and Challenges

Hafiz Ishfaq Ahmad,
Muhammad Jamil Ahmad,
Akhtar Rasool Asif,
Muhammad Adnan,
Muhammad Kashif Iqbal,
Khalid Mehmood,
Sayyed Aun Muhammad,
Ali Akbar Bhuiyan,
Abdelmotaleb Elokil and
Xiaoyong Du
+ 3 authors

Curr. Issues Mol. Biol.2018, 28(1), 47-68;https://doi.org/10.21775/cimb.028.047

11 February 2018

Precise nucleic acid editing technologies have facilitated the research of cellular function and the development of novel therapeutics, especially the current programmable nucleases-based editing tools, such as the prokaryotic clustered regularly int...

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Review

18 Citations

1,319 Views

15 Pages

Snapshots: Endoplasmic Reticulum Stress in Lipid Metabolism and Cardiovascular Disease

Tian Li,
Shuai Jiang,
Chenxi Lu,
Wei Hu,
Ting Ji,
Mengzhen Han,
Yang Yang and
Zhenxiao Jin

Curr. Issues Mol. Biol.2018, 28(1), 14-28;https://doi.org/10.21775/cimb.028.014

1 February 2018

The endoplasmic reticulum (ER) is an organelle present in most eukaryotic cells and plays a pivotal role in lipid metabolism. ER dysfunction, specifically ER stress (ERS), is a pathophysiological response involved in lipid metabolism and cardiovascul...

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Review

121 Citations

2,379 Views

18 Pages

PGC-1: The Energetic Regulator in Cardiac Metabolism

Wencheng Di,
Jianjun Lv,
Shuai Jiang,
Chenxi Lu,
Zhi Yang,
Zhiqiang Ma,
Wei Hu,
Yang Yang and
Biao Xu

Curr. Issues Mol. Biol.2018, 28(1), 29-46;https://doi.org/10.21775/cimb.028.029

1 February 2018

The peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1s (PGC-1s) can induce the expression of several downstream genes that play pivotal roles in the regulation of mitochondrial biogenesis and metabolism in the heart. Moreover, PGC-1...

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Review

9 Citations

562 Views

14 Pages

Translational Approaches In Cardiovascular Diseases by "Omics"

Vahideh Rabani and
Siamak Davani

Curr. Issues Mol. Biol.2018, 28(1), 1-14;https://doi.org/10.21775/cimb.028.001

12 September 2017

Cardiovascular diseases are among the leading causes of morbidity and mortality. Despite scientific and technical progress in risk prediction, diagnostics, prognostication and therapy of cardiovascular pathologies, new biomarkers and therapeutic targ...

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Curr. Issues Mol. Biol. - ISSN 1467-3045

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