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Pharmaceuticals, Volume 17, Issue 11

November 2024 - 150 articles

Cover Story: Freeze-drying is a dehydration method that extends the shelf life and stability of drugs, vaccines, and biologics. Recently, its role has expanded beyond preservation to improve novel pharmaceuticals and their carriers, such as hydrogels, which are widely studied for both drug delivery and wound healing. This article highlights the multifunctional role of freeze-drying in improving the properties of sodium alginate/poly(vinyl alcohol)-based hydrogels for pharmaceutical delivery. The results show a high potential for commercialisation of the obtained hydrogels as medical dressings. View this paper
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Articles (150)

  • Article
  • Open Access
2,387 Views
24 Pages

Identification of Estrogen-Responsive Proteins in Mouse Seminal Vesicles Through Mass Spectrometry-Based Proteomics

  • Ammar Kapic,
  • Khadiza Zaman,
  • Vien Nguyen,
  • Katalin Prokai-Tatrai and
  • Laszlo Prokai

9 November 2024

Background: Although estrogenic compounds promise therapeutic potential in treating various conditions, concerns regarding their endocrine-disrupting effects have been raised. Current methodologies for screening estrogenicity in rodent models are lim...

  • Article
  • Open Access
5 Citations
2,328 Views
16 Pages

Berberine Mediates Exosomes Regulating the Lipid Metabolism Pathways to Promote Apoptosis of RA-FLS Cells

  • Si-Fan Guo,
  • Zhi-Bo Wang,
  • Dan-Dan Xie,
  • Ying Cai,
  • Yan Wang,
  • Xian Wang,
  • Qiang Yang,
  • Ai-Hua Zhang and
  • Shi Qiu

9 November 2024

Objectives: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint damage and commonly linked to symptoms such as inflammation, swelling, and pain. Traditional Chinese Medicine offers complementary and integrative approaches...

  • Review
  • Open Access
6 Citations
10,470 Views
20 Pages

The Therapeutic Management of Chemical and Herbal Medications on Uric Acid Levels and Gout: Modern and Traditional Wisdom

  • Zhijian Lin,
  • Jeetendra Kumar Gupta,
  • Mohsin Maqbool,
  • Krishan Kumar,
  • Ayushi Sharma and
  • Nitin Wahi

9 November 2024

Background: Gout is a chronic inflammatory condition characterized by elevated uric acid levels in the blood, which can precipitate acute gout attacks in individuals with genetic susceptibility, existing medical conditions, and dietary influences. Ge...

  • Review
  • Open Access
4 Citations
3,133 Views
15 Pages

Analgosedation in Pediatric Emergency Care: A Comprehensive Scoping Review

  • Lorenzo Ciavola,
  • Francesco Sogni,
  • Benedetta Mucci,
  • Eleonora Alfieri,
  • Angela Tinella,
  • Elena Mariotti Zani and
  • Susanna Esposito

8 November 2024

Effective management of pain and anxiety in pediatric emergency room is crucial for ensuring both the physical and emotional well-being of young patients. Analgosedation, a combination of analgesia and sedation, is commonly used to facilitate various...

  • Review
  • Open Access
31 Citations
12,551 Views
15 Pages

Anti-Inflammatory and Antioxidant Activities of Eugenol: An Update

  • Renan Oliveira Silva Damasceno,
  • João Lucas Silva Pinheiro,
  • Lucas Henrique Marques Rodrigues,
  • Rebeca Carneiro Gomes,
  • Allana Brunna Sucupira Duarte,
  • Jeremias Justo Emídio,
  • Lúcio Ricardo Leite Diniz and
  • Damião Pergentino de Sousa

8 November 2024

Medicinal plants are a rich source of bioactive compounds that possess pharmacological properties for preventing and treating inflammation-related diseases. Essential oils is a chemical class that contains many bioactive compounds, such as eugenol, w...

  • Article
  • Open Access
5 Citations
2,522 Views
17 Pages

Levamisole Ameliorates Rheumatoid Arthritis by Downregulating the PI3K/Akt Pathway in SD Rats

  • Mu Guo,
  • Xiangbin Yu,
  • Zesheng Yang,
  • Hanlu Zheng,
  • Jiahui Zhang,
  • Junxiang Wang,
  • Yiqi Liao,
  • Weirui Huang,
  • Zhaolong Lin and
  • Yingxue Yan
  • + 3 authors

8 November 2024

Background/Objectives: Rheumatoid arthritis (RA) is a systemic chronic autoimmune disease characterized by a protracted course, high rates of morbidity, and disability yet lacks effective therapeutic modalities. Levamisole (LVM), an immunomodulatory...

  • Article
  • Open Access
4 Citations
1,740 Views
17 Pages

M2e-Derived Peptidyl and Peptide Amphiphile Micelles as Novel Influenza Vaccines

  • Megan C. Schulte,
  • Agustin T. Barcellona,
  • Xiaofei Wang,
  • Adam G. Schrum and
  • Bret D. Ulery

8 November 2024

Background: A significant problem with current influenza vaccines is their reliance on predictions of the most prevalent strains for the upcoming season, with inaccurate forecasts greatly reducing the overall efficacy of the immunization campaign. A...

  • Article
  • Open Access
6 Citations
2,103 Views
22 Pages

8 November 2024

Background: Suk-Saiyasna is a traditional Thai herbal remedy that comprises 12 distinct herbs. Among these, cannabis leaves constitute 12 of the total 78 components in this formulation. This study specifically examines the portion of the cannabis pla...

  • Article
  • Open Access
1 Citations
1,386 Views
13 Pages

8 November 2024

Background: Bradykinin is an endogenously produced nonapeptide with many physiological and pathological functions that are mediated by two pharmacologically defined receptor subtypes, B1- and B2-receptors. Current studies sought to characterize the f...

  • Article
  • Open Access
3,274 Views
12 Pages

Benign Evolution of Complex Regional Pain Syndrome (CRPS) Type 1 in Patients Treated with Intravenous Neridronate: A Single-Center Real-Life Experience

  • Jacopo Ciaffi,
  • Gianluca Festuccia,
  • Claudio Ripamonti,
  • Luana Mancarella,
  • Veronica Brusi,
  • Federica Pignatti,
  • Lucia Lisi,
  • Lisa Berti,
  • Piero Ruscitti and
  • Cesare Faldini
  • + 1 author

8 November 2024

Objective: To investigate the long-term effects of intravenous neridronate treatment in patients with complex regional pain syndrome type 1 (CRPS) in a real-life setting. Methods: We conducted a retrospective study on consecutive CRPS patients treate...

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Pharmaceuticals - ISSN 1424-8247