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Sensors 2014, 14(1), 1184-1194;

Biosensing Using Microring Resonator Interferograms

Department of Electronic Engineering, National Taiwan University of Science and Technology, No.43, Sec. 4, Keelung Rd., Taipei 10607, Taiwan
School of Medical Laboratory Science and Biotechnology, College of Medical Science and Technology, Taipei Medical University, 250 Wu-Hsing Street, Taipei 11031, Taiwan
Authors to whom correspondence should be addressed.
Received: 20 November 2013 / Revised: 16 December 2013 / Accepted: 3 January 2014 / Published: 10 January 2014
(This article belongs to the Section Biosensors)
Full-Text   |   PDF [559 KB, uploaded 21 June 2014]


Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor (Q), proportional to the effective length, could be improved using the silicon-wire propagation loss and coupling ratio from the MRR coupler. Our study showed that multimode interference (MMI) performed well in broad band response, but the splitting ratio drifted to 75/25 due to the stress issue. The glucose sensing sensitivity demonstrated 0.00279 meter per refractive-index-unit (RIU) with a Q factor of ~30,000 under transverse electric polarization. The 1,310 nm DFB laser was built in the OLCI system as the optical ruler achieving 655 nm characterization accuracy. The lowest sensing limitation was therefore 2 × 10−4 RIU. Moreover, the MRR effective length from the glucose sensitivity could be utilized to experimentally demonstrate the silicon wire effective refractive index with a width of 0.45 mm and height of 0.26 mm. View Full-Text
Keywords: interferometry; biophotonics; microring resonator; silicon wire; multimode interference; birefringence interferometry; biophotonics; microring resonator; silicon wire; multimode interference; birefringence
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Hsu, S.-H.; Yang, Y.-C.; Su, Y.-H.; Wang, S.-M.; Huang, S.-A.; Lin, C.-Y. Biosensing Using Microring Resonator Interferograms. Sensors 2014, 14, 1184-1194.

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