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Short Note

Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate

Engineering Laboratory of Organometallic, Molecular Materials and Environment (LIMOME), Faculty of Sciences Dhar El Mahraz, Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco
Team of Organic Chemistry and Valorization of Natural Substances, Faculty of Sciences, Ibn Zohr University, Agadir 80060, Morocco
City of Innovation, Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco
Author to whom correspondence should be addressed.
Academic Editor: Bartolo Gabriele
Molbank 2021, 2021(4), M1285;
Received: 18 August 2021 / Revised: 28 September 2021 / Accepted: 1 October 2021 / Published: 4 October 2021
(This article belongs to the Special Issue Metal-Catalyzed Synthesis)
We have previously published new biheterocyclic phospohonic α-amino esters of the 1,2,3-triazole-benzimidazole and 1,2,3-triazole-carbazole type. The aim of the present paper was to describe a new phosponic aminoester bearing a triazole ring substituted in position 5 by an ester group. Thus, according to the same catalytic process used previously, the compound naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate was synthesized with an excellent yield and high regioselectivity via the copper (I)-catalyzed alkyne–azide cycloaddition reaction (CuAAC), using diethyl (α-azido(benzamido)methyl)phosphonate (1) as a dipole and 2- naphthyl propiolate as a dipolarophile (2). The structure of the new compound was fully characterized by 1D (31P, 1H-, 13C-) and 2D (1H-1H and 1H-, 13C-) NMR spectroscopy, IR, and HRMS. View Full-Text
Keywords: triazole; α-amino phosphonic ester; 1,3-dipolar cycloaddition; click chemistry; 1D and 2D NMR; HRMS triazole; α-amino phosphonic ester; 1,3-dipolar cycloaddition; click chemistry; 1D and 2D NMR; HRMS
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MDPI and ACS Style

Fall, S.A.K.; Hajib, S.; Karai, O.; Boukhssas, S.; Aouine, Y.; Akhazzane, M.; Labriti, B.; Faraj, H.; Alami, A. Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate. Molbank 2021, 2021, M1285.

AMA Style

Fall SAK, Hajib S, Karai O, Boukhssas S, Aouine Y, Akhazzane M, Labriti B, Faraj H, Alami A. Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate. Molbank. 2021; 2021(4):M1285.

Chicago/Turabian Style

Fall, Serigne A.K., Sara Hajib, Oumaima Karai, Salaheddine Boukhssas, Younas Aouine, Mohamed Akhazzane, Brahim Labriti, Hassane Faraj, and Anouar Alami. 2021. "Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate" Molbank 2021, no. 4: M1285.

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