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Microwave-Assisted Synthesis of Schiff Bases of Isoniazid and Evaluation of Their Anti-Proliferative and Antibacterial Activities
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Department of Life Sciences, School of Sciences, European University Cyprus, 6 Diogenis Str., Engomi, P. O. Box 22006, Nicosia 1516, Cyprus
Department of Chemistry, University of Cyprus, P. O. Box 20537, Nicosia 1678, Cyprus
Author to whom correspondence should be addressed.
Academic Editor: Nicholas E. Leadbeater
Molbank 2021, 2021(1), M1190;
Received: 21 January 2021 / Revised: 2 February 2021 / Accepted: 4 February 2021 / Published: 9 February 2021
(This article belongs to the Section Organic Synthesis)
Reaction of 4,5,6-trichloropyrimidine-2-carbonitrile (1) with concentrated sulfuric acid at ca. 20 °C gave 4,5,6-trichloropyrimidine-2-carboxamide (5) in 91% yield. The new compound was fully characterized by IR, MALDI-TOF, NMR and elemental analysis. View Full-Text
Keywords: heterocycle; chloro-substituted; pyrimidine; carboxamide heterocycle; chloro-substituted; pyrimidine; carboxamide
MDPI and ACS Style

Kalogirou, A.S.; Koutentis, P.A. 4,5,6-Trichloropyrimidine-2-carboxamide. Molbank 2021, 2021, M1190.

AMA Style

Kalogirou AS, Koutentis PA. 4,5,6-Trichloropyrimidine-2-carboxamide. Molbank. 2021; 2021(1):M1190.

Chicago/Turabian Style

Kalogirou, Andreas S.; Koutentis, Panayiotis A. 2021. "4,5,6-Trichloropyrimidine-2-carboxamide" Molbank 2021, no. 1: M1190.

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