Next Article in Journal / Special Issue
(2S,5R)-2-Isopropyl-5-methylcyclohexanone Hydrazones
Previous Article in Journal
Synthesis of 1H-3-{4-[(3-Dimethylaminopropyl)aminomethyl]phenyl}-2-phenylindole and Evaluation of Its Antiprotozoal Activity
Previous Article in Special Issue
(E)-N′-(4-Fluorobenzylidene)-5-methyl-2-(pyridin-3-yl)thiazole-4-carbohydrazide
Open AccessCommunication

4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one

1
Department of Chemistry, M. V. Lomonosov Moscow State University, Leninskie gory 1-3, Moscow 119991, Russian
2
Laboratory of High Technologies, Ltd. Vernadskogo 86, Moscow 119571, Russian
3
Laboratory of Chemical Synthesis, Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Samory Mashela 1, Moscow 117997, Russian
4
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky pr. 47, Moscow 119991, Russian
*
Authors to whom correspondence should be addressed.
Molbank 2019, 2019(2), M1061; https://doi.org/10.3390/M1061
Received: 27 April 2019 / Revised: 13 May 2019 / Accepted: 16 May 2019 / Published: 17 May 2019
(This article belongs to the Collection Molecules from Catalytic Processes)
A simple approach to synthesize 4b,5,6,9-tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin- 7-one has been developed, based on a three-step transformation of 2-(2-bromophenyl)cyclopropane-1,1-diester. The key stage in this method is an intramolecular cross-coupling of 1-(2-bromobenzyl)-5-(2-bromophenyl)pyrrolidin-2-one under continuous flow conditions in an H-Сube-Pro using commercially available supported Pd catalysts. View Full-Text
Keywords: donor-acceptor cyclopropanes; tetrahydrodibenzo[c,e]pyrrolo[1,2-a]azepines; cross-coupling reactions; flow chemistry donor-acceptor cyclopropanes; tetrahydrodibenzo[c,e]pyrrolo[1,2-a]azepines; cross-coupling reactions; flow chemistry
Show Figures

Graphical abstract

MDPI and ACS Style

Boichenko, M.A.; Babkin, I.Y.; Kobylskoy, S.G.; Chagarovskiy, A.O.; Ivanova, O.A.; Trushkov, I.V. 4b,5,6,9-Tetrahydro-7H-dibenzo[c,e]pyrrolo[1,2-a]azepin-7-one. Molbank 2019, 2019, M1061.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop