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Biosynthesis of Natural Rubber: Current State and Perspectives

1
CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No.189 Songling Road, Laoshan District, Qingdao 266101, China
2
University of Chinese Academy of Sciences, Beijing 100049, China
*
Authors to whom correspondence should be addressed.
Int. J. Mol. Sci. 2019, 20(1), 50; https://doi.org/10.3390/ijms20010050
Received: 4 November 2018 / Revised: 17 December 2018 / Accepted: 19 December 2018 / Published: 22 December 2018
(This article belongs to the Section Molecular Plant Sciences)
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PDF [2311 KB, uploaded 23 December 2018]
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Abstract

Natural rubber is a kind of indispensable biopolymers with great use and strategic importance in human society. However, its production relies almost exclusively on rubber-producing plants Hevea brasiliensis, which have high requirements for growth conditions, and the mechanism of natural rubber biosynthesis remains largely unknown. In the past two decades, details of the rubber chain polymerization and proteins involved in natural rubber biosynthesis have been investigated intensively. Meanwhile, omics and other advanced biotechnologies bring new insight into rubber production and development of new rubber-producing plants. This review summarizes the achievements of the past two decades in understanding the biosynthesis of natural rubber, especially the massive information obtained from the omics analyses. Possibilities of natural rubber biosynthesis in vitro or in genetically engineered microorganisms are also discussed. View Full-Text
Keywords: natural rubber biosynthesis; rubber particles; cis-prenyltransferase (CPT); Hevea rubber transferase 1 (HRT1); rubber elongation factor (REF); small rubber particle protein (SRPP); HRT1-REF bridging protein (HRBP); Hevea brasiliensis natural rubber biosynthesis; rubber particles; cis-prenyltransferase (CPT); Hevea rubber transferase 1 (HRT1); rubber elongation factor (REF); small rubber particle protein (SRPP); HRT1-REF bridging protein (HRBP); Hevea brasiliensis
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Men, X.; Wang, F.; Chen, G.-Q.; Zhang, H.-B.; Xian, M. Biosynthesis of Natural Rubber: Current State and Perspectives. Int. J. Mol. Sci. 2019, 20, 50.

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