Next Article in Journal
Substituted Amides of Pyrazine-2-carboxylic acids: Synthesis and Biological Activity
Previous Article in Journal
Synthesis and Rearrangement of 3-Methyl-1,4-pentadiyne-3-ol
Article Menu

Export Article

Open AccessArticle
Molecules 2002, 7(3), 353-362;

Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione

Department of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica
Author to whom correspondence should be addressed.
Published: 31 March 2002
Full-Text   |   PDF [104 KB, uploaded 18 June 2014]   |  


Treatment of 5,6-dimethoxy-2-(methylphenylcarbamoyl)-benzofuran-3-carboxylic acid with PPA yielded 2,3-dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. The analogous 2-[(5,6-dimethoxybenzofuran-2-carbonyl)methylamino]benzoic acid was resistant to cyclization, whereas 2-[(6-methoxybenzofuran-2-carbonyl)-amino]benzoic acid underwent cyclization to the corresponding 3,1-benzoxazin-4-one. View Full-Text
Keywords: PPA; cyclization; benzoxazinone; benzofuro-[2; 3-c]-[1]-benzazepin-6; 12-dione PPA; cyclization; benzoxazinone; benzofuro-[2; 3-c]-[1]-benzazepin-6; 12-dione

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Jackson, Y.A.; Marriott, K.-S.C. Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. Molecules 2002, 7, 353-362.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top