Next Issue
Volume 7, April
Previous Issue
Volume 7, February
molecules-logo

Journal Browser

Journal Browser

Table of Contents

Molecules, Volume 7, Issue 3 (March 2002) – 5 articles , Pages 320-373

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
Order results
Result details
Select all
Export citation of selected articles as:
Open AccessArticle
Substituted Amides of Pyrazine-2-carboxylic acids: Synthesis and Biological Activity
Molecules 2002, 7(3), 363-373; https://doi.org/10.3390/70300363 - 31 Mar 2002
Cited by 45 | Viewed by 8285
Abstract
Condensation of 6-chloro-, 5-tert-butyl- or 6-chloro-5-tert-butylpyrazine-2-carboxylic acid chloride with ring substituted anilines yielded a series of amides, which were tested for their in vitro antimycobacterial, antifungal and photosynthesis-inhibiting activities. The highest antituberculotic activity (72% inhibition) against Mycobacterium tuberculosis and [...] Read more.
Condensation of 6-chloro-, 5-tert-butyl- or 6-chloro-5-tert-butylpyrazine-2-carboxylic acid chloride with ring substituted anilines yielded a series of amides, which were tested for their in vitro antimycobacterial, antifungal and photosynthesis-inhibiting activities. The highest antituberculotic activity (72% inhibition) against Mycobacterium tuberculosis and the highest lipophilicity (log P = 6.85) were shown by the 3,5-bistrifluoromethylphenyl amide of 5-tert-butyl-6-chloropyrazine-2-carboxylic acid (2o). The 3-methylphenyl amides of 6-chloro- and 5-tert-butyl-6-chloro-pyrazine-2-carboxylic acid (2d and 2f) exhibited only a poor in vitro antifungal effect (MIC = 31.25-500 μmol·dm-3) against all strains tested, although the latter was the most active antialgal compound (IC50 = 0.063 mmol·dm-3). The most active inhibitor of oxygen evolution rate in spinach chloroplasts was the (3,5-bis-trifluoromethylphenyl)amide of 6-chloropyrazine-2-carboxylic acid (2m, IC50 = 0.026 mmol·dm-3). Full article
Show Figures

Figure 1

Open AccessArticle
Synthesis of 2,3-Dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione
Molecules 2002, 7(3), 353-362; https://doi.org/10.3390/70300353 - 31 Mar 2002
Cited by 5 | Viewed by 5290
Abstract
Treatment of 5,6-dimethoxy-2-(methylphenylcarbamoyl)-benzofuran-3-carboxylic acid with PPA yielded 2,3-dimethoxy-7-methyl-7,12-dihydro-6H-[1]-benzofuro-[2,3-c]-[1]-benzazepin-6,12-dione. The analogous 2-[(5,6-dimethoxybenzofuran-2-carbonyl)methylamino]benzoic acid was resistant to cyclization, whereas 2-[(6-methoxybenzofuran-2-carbonyl)-amino]benzoic acid underwent cyclization to the corresponding 3,1-benzoxazin-4-one. Full article
Show Figures

Figure 1

Open AccessArticle
Synthesis and Rearrangement of 3-Methyl-1,4-pentadiyne-3-ol
Molecules 2002, 7(3), 341-352; https://doi.org/10.3390/70300341 - 31 Mar 2002
Cited by 5 | Viewed by 6526
Abstract
An efficient synthesis and rearrangement of 3-methyl-1,4-pentadiyne-3-ol (1) using perrhenate- and Mo(VI)-catalysts is reported. The by-products 3,6-dimethyl-1,4,7-octatriyne-3,6-diol (2) and 3-ethynyl-5-methyl-1,6-heptadiyne-3,5-diol (3) were isolated and spectroscopically characterized. A possible reaction mechanism for the formation of the byproducts is discussed. Full article
Show Figures

Figure 1

Open AccessArticle
Correlation between Phenylphenalenone Phytoalexins and Phytopathological Properties in Musa and the Role of a Dihydrophenylphenalene Triol
Molecules 2002, 7(3), 331-340; https://doi.org/10.3390/70300331 - 31 Mar 2002
Cited by 17 | Viewed by 6351
Abstract
A correlation has been established between production of specific phenylphenalenones and resistance of various banana and plantain varieties towards certain pathogens. In addition a dihydrotrihydroxyphenylphenalene was isolated from the resistant 'Pelipita' plantain variety in relatively high concentrations and its structure and relative configuration [...] Read more.
A correlation has been established between production of specific phenylphenalenones and resistance of various banana and plantain varieties towards certain pathogens. In addition a dihydrotrihydroxyphenylphenalene was isolated from the resistant 'Pelipita' plantain variety in relatively high concentrations and its structure and relative configuration were assigned on the basis of 1D and 2D NMR and NOE information. This compound is considered a key intermediate in the biosynthesis of phenylphenalenone phytoalexins. Full article
Show Figures

Figure 1

Open AccessArticle
Synthesis and Spectroscopic Characterisation of N-Alkyl Quaternary Ammonium Salts Typical Precursors of Cyanines
Molecules 2002, 7(3), 320-330; https://doi.org/10.3390/70300320 - 31 Mar 2002
Cited by 71 | Viewed by 9605
Abstract
The synthesis and spectroscopic characterisation of some representative N-alkylsubstituted quaternary ammonium salts derived from benzothiazole, benzoxazole, benzoselenazole, indole and quinoline are described. These heterocyclic salts, bearing an activated methyl group in the 2-position in relation to the nitrogen atom and N-methyl, [...] Read more.
The synthesis and spectroscopic characterisation of some representative N-alkylsubstituted quaternary ammonium salts derived from benzothiazole, benzoxazole, benzoselenazole, indole and quinoline are described. These heterocyclic salts, bearing an activated methyl group in the 2-position in relation to the nitrogen atom and N-methyl, -pentyl, -hexyl and -decyl chains, are typical precursors of cyanine dyes. Full article
Show Figures

Figure 1

Previous Issue
Next Issue
Back to TopTop