Next Article in Journal
Molecular Disorder in (‒)-Encecanescin
Previous Article in Journal
Cornu Cervi Pantotrichum Supplementation Improves Exercise Performance and Protects against Physical Fatigue in Mice
Article

In Vitro Antioxidant Activities, Free Radical Scavenging Capacity, and Tyrosinase Inhibitory of Flavonoid Compounds and Ferulic Acid from Spiranthes sinensis (Pers.) Ames

1
Department of Medicinal Botanicals and Health Applications, Da-Yeh University, Changhua 51591, Taiwan
2
Cheng Ching General Hospital, Taichung 42881, Taiwan
3
Horien International Co., Ltd., Taichung 42881, Taiwan
4
Pemay Biomedical Technology Corp, Taichung 41348, Taiwan
*
Author to whom correspondence should be addressed.
Molecules 2014, 19(4), 4681-4694; https://doi.org/10.3390/molecules19044681
Received: 24 January 2014 / Revised: 2 April 2014 / Accepted: 3 April 2014 / Published: 15 April 2014
(This article belongs to the Section Natural Products Chemistry)
In this study, ultrasound-assisted extraction (UAE) and other methods of extracting flavonoid compounds and ferulic acid (FA) from S. sinensis were investigated. Five different extraction methods, including water extraction (W), water extraction using UAE (W+U), 75% ethanol extraction (E), 75% ethanol extraction using UAE (E+U), and supercritical CO2 extraction (SFE) were applied in the extraction of bioactive compounds (flavonoids and ferulic acid) in order to compare their efficiency. The highest yield of flavonoids (4.28 mg/g) and ferulic acid (4.13 mg/g) content was detected in the E+U extract. Furthermore, S. sinensis extracts obtained by E+U show high antioxidant activity, and IC50 values of 0.47 mg/mL for DPPH radicals and 0.205 mg/mL for metal chelating activity. The total antioxidant assay shows superoxide radical scavenging capacity and in vitro mushroom tyrosinase inhibition in a dose-dependent manner, suggesting that E+U can be used for extraction of bioactive compounds from S. sinensis. View Full-Text
Keywords: Spiranthes sinensis; ultrasound-assisted extraction; ferulic acid; flavonoids; antioxidant activity; tyrosinase Spiranthes sinensis; ultrasound-assisted extraction; ferulic acid; flavonoids; antioxidant activity; tyrosinase
Show Figures

Figure 1

MDPI and ACS Style

Liang, C.P.; Chang, C.H.; Liang, C.C.; Hung, K.Y.; Hsieh, C.W. In Vitro Antioxidant Activities, Free Radical Scavenging Capacity, and Tyrosinase Inhibitory of Flavonoid Compounds and Ferulic Acid from Spiranthes sinensis (Pers.) Ames. Molecules 2014, 19, 4681-4694. https://doi.org/10.3390/molecules19044681

AMA Style

Liang CP, Chang CH, Liang CC, Hung KY, Hsieh CW. In Vitro Antioxidant Activities, Free Radical Scavenging Capacity, and Tyrosinase Inhibitory of Flavonoid Compounds and Ferulic Acid from Spiranthes sinensis (Pers.) Ames. Molecules. 2014; 19(4):4681-4694. https://doi.org/10.3390/molecules19044681

Chicago/Turabian Style

Liang, Chung P., Chia H. Chang, Chien C. Liang, Kuei Y. Hung, and Chang W. Hsieh 2014. "In Vitro Antioxidant Activities, Free Radical Scavenging Capacity, and Tyrosinase Inhibitory of Flavonoid Compounds and Ferulic Acid from Spiranthes sinensis (Pers.) Ames" Molecules 19, no. 4: 4681-4694. https://doi.org/10.3390/molecules19044681

Find Other Styles

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop