A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental
3.1. General Information
3.2. General Procedure for the Synthesis of Compounds 2–4
3.3. Alternative Method for the Synthesis of 2,4-Diethyl-5-(methoxycarbonyl)-6-phenylpyridine-3-carbothioic S-acid (2)
3.4. General Procedure for the Synthesis of Compounds 5‒7
3.5. Synthesis of 2-Fluoroethyl 4,6-Diethyl-5-{[(2-fluoroethyl)sulfanyl]carbonyl}-2-phenylpyridine-3-carboxylate (8)
4. Conclusions
Supplementary Materials
Acknowledgments
Conflicts of Interest
References
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Shanab, K.; Neudorfer, C.; Holzer, W.; Mitterhauser, M.; Wadsak, W.; Spreitzer, H. A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer. Molecules 2014, 19, 4076-4082. https://doi.org/10.3390/molecules19044076
Shanab K, Neudorfer C, Holzer W, Mitterhauser M, Wadsak W, Spreitzer H. A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer. Molecules. 2014; 19(4):4076-4082. https://doi.org/10.3390/molecules19044076
Chicago/Turabian StyleShanab, Karem, Catharina Neudorfer, Wolfgang Holzer, Markus Mitterhauser, Wolfgang Wadsak, and Helmut Spreitzer. 2014. "A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer" Molecules 19, no. 4: 4076-4082. https://doi.org/10.3390/molecules19044076
APA StyleShanab, K., Neudorfer, C., Holzer, W., Mitterhauser, M., Wadsak, W., & Spreitzer, H. (2014). A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer. Molecules, 19(4), 4076-4082. https://doi.org/10.3390/molecules19044076