Topical Collection "Marine Polysaccharides"

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A topical collection in Marine Drugs (ISSN 1660-3397).

Editor

Collection Editor
Dr. Paola Laurienzo
Istituto di Chimica e Tecnologia dei Polimeri, C.N.R.-Via Campi Flegrei, 34-80078 Pozzuoli (Naples), Italy
Website: http://www.ictp.cnr.it/laurienzo.html
Fax: +39 818 675 230

Topical Collection Information

Dear Colleagues,

Biopolymers, as natural polysaccharides, are considered benign polymers for what concerns the environment. This is not a new invention, but at best a renaissance: the first type of polymers used by human kind were animal hides, cellulose, silk, wool. Among benefits of natural occurring biopolymers there are potential biocompatibility, renewable resources, low processing costs, tailoring of structure by genetic manipulation, and, as said, environmentally compatibility. Limits are, sometimes, premature degradation and high production costs due to the very high purity required for medical uses. Polysaccharides are not drugs by themselves, but their use in pharmaceutical field, for example as drug carriers or antimicrobial, anti-inflammatory or anticoagulant agents, is increasingly promising. Marine polysaccharides include chitin, chitosan, alginate, agar and carrageenans. Chitosan is a cationic carbohydrate biopolymer derived from chitin, the second most abundant polysaccharides present in nature after cellulose. The main sources of chitin are the shell wastes of shrimps, lobsters and crabs. For its characteristics, chitosan founds particular application as non viral vector in gene delivery. Films from chitosan are very tough and long lasting. Alginates derive from seaweed extraction (pheophyceae), and are mainly used in drug delivery and as hydrogels for immobilizing cells and enzymes, due to the mild conditions of cross-linking through bivalent cations (Ca2+). Agar (or agar-agar) and carrageenans are linear polysaccharides from red seaweeds. They are highly reactive chemically and are peculiar for thermoreversible gel formation. Exopolysaccharides (EPS), substantial components of the extracellular matrix of many cells of marine origin, also have to be mentioned for their potential interest in pharmaceuticals, and new EPS producing bacteria, particularly from extreme marine environments, are being isolated.
The possibility of chemical modification, blending and addition of biodegradable additives allows to tailor the final properties of polysaccharides and opens the doors to wider applications, particularly in pharmaceutical area. This issue is intended to explore any new potentiality of marine polysaccharides, as those above mentioned, deriving from chemical or chemical-physical modifications, and the scaling-up of their pharmaceutical applications.

Dr. Paola Laurienzo
Collection Editor

Manuscript Submission Information

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Keywords

  • chitosan
  • alginate
  • agar
  • carrageenans
  • exopolysaccharides
  • chemical modification
  • drug delivery
  • gene delivery

Published Papers (39 papers)

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2015  ( 21 papers )


2014  ( 1 paper )


2013  ( 2 papers )


2012  ( 2 papers )


2011  ( 7 papers )


2010  ( 6 papers )


2015
by , , , , ,  and
Mar. Drugs 2015, 13(7), 4270-4280; doi:10.3390/md13074270
Received: 14 April 2015 / Revised: 30 June 2015 / Accepted: 1 July 2015 / Published: 10 July 2015
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by , ,  and
Mar. Drugs 2015, 13(7), 4156-4170; doi:10.3390/md13074156
Received: 26 May 2015 / Revised: 17 June 2015 / Accepted: 23 June 2015 / Published: 30 June 2015
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by , , ,  and
Mar. Drugs 2015, 13(6), 3287-3308; doi:10.3390/md13063287
Received: 20 February 2015 / Accepted: 13 May 2015 / Published: 27 May 2015
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by ,  and
Mar. Drugs 2015, 13(6), 3340-3359; doi:10.3390/md13063340
Received: 28 February 2015 / Accepted: 13 May 2015 / Published: 27 May 2015
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by ,  and
Mar. Drugs 2015, 13(5), 2967-3028; doi:10.3390/md13052967
Received: 10 March 2015 / Revised: 26 April 2015 / Accepted: 4 May 2015 / Published: 15 May 2015
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by , , , , , , ,  and
Mar. Drugs 2015, 13(5), 3072-3090; doi:10.3390/md13053072
Received: 21 February 2015 / Revised: 8 April 2015 / Accepted: 4 May 2015 / Published: 15 May 2015
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by , , ,  and
Mar. Drugs 2015, 13(5), 2890-2908; doi:10.3390/md13052890
Received: 24 February 2015 / Revised: 2 April 2015 / Accepted: 29 April 2015 / Published: 11 May 2015
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by , , , , ,  and
Mar. Drugs 2015, 13(5), 2875-2889; doi:10.3390/md13052875
Received: 27 February 2015 / Revised: 18 April 2015 / Accepted: 27 April 2015 / Published: 8 May 2015
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by
Mar. Drugs 2015, 13(5), 2770-2784; doi:10.3390/md13052770
Received: 26 February 2015 / Revised: 14 April 2015 / Accepted: 17 April 2015 / Published: 6 May 2015
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by ,  and
Mar. Drugs 2015, 13(5), 2680-2693; doi:10.3390/md13052680
Received: 3 March 2015 / Revised: 17 April 2015 / Accepted: 17 April 2015 / Published: 29 April 2015
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by , , , , , , , ,  and
Mar. Drugs 2015, 13(4), 2424-2446; doi:10.3390/md13042424
Received: 19 February 2015 / Revised: 23 March 2015 / Accepted: 27 March 2015 / Published: 20 April 2015
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by , , ,  and
Mar. Drugs 2015, 13(4), 2447-2464; doi:10.3390/md13042447
Received: 5 February 2015 / Revised: 28 March 2015 / Accepted: 30 March 2015 / Published: 20 April 2015
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by , , , , , , , ,  and
Mar. Drugs 2015, 13(4), 2063-2084; doi:10.3390/md13042063
Received: 26 January 2015 / Revised: 25 March 2015 / Accepted: 26 March 2015 / Published: 13 April 2015
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by
Mar. Drugs 2015, 13(4), 2158-2182; doi:10.3390/md13042158
Received: 19 February 2015 / Revised: 23 March 2015 / Accepted: 26 March 2015 / Published: 13 April 2015
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by , , , , , , ,  and
Mar. Drugs 2015, 13(4), 1882-1900; doi:10.3390/md13041882
Received: 12 February 2015 / Revised: 26 March 2015 / Accepted: 27 March 2015 / Published: 3 April 2015
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by  and
Mar. Drugs 2015, 13(4), 1819-1846; doi:10.3390/md13041819
Received: 25 February 2015 / Revised: 19 March 2015 / Accepted: 20 March 2015 / Published: 1 April 2015
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by  and
Mar. Drugs 2015, 13(4), 1847-1863; doi:10.3390/md13041847
Received: 24 February 2015 / Revised: 23 March 2015 / Accepted: 25 March 2015 / Published: 1 April 2015
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by , , , , , , ,  and
Mar. Drugs 2015, 13(4), 1798-1818; doi:10.3390/md13041798
Received: 5 February 2015 / Revised: 15 March 2015 / Accepted: 20 March 2015 / Published: 30 March 2015
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by , , , , ,  and
Mar. Drugs 2015, 13(3), 1360-1374; doi:10.3390/md13031360
Received: 15 January 2015 / Revised: 2 March 2015 / Accepted: 5 March 2015 / Published: 16 March 2015
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by , , , , , ,  and
Mar. Drugs 2015, 13(3), 1267-1289; doi:10.3390/md13031267
Received: 1 December 2014 / Revised: 8 February 2015 / Accepted: 9 February 2015 / Published: 12 March 2015
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by , ,  and
Mar. Drugs 2015, 13(2), 936-947; doi:10.3390/md13020936
Received: 8 December 2014 / Accepted: 3 February 2015 / Published: 12 February 2015
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2014
by , , , ,  and
Mar. Drugs 2014, 12(9), 4883-4897; doi:10.3390/md12094883
Received: 26 June 2014 / Revised: 9 September 2014 / Accepted: 9 September 2014 / Published: 23 September 2014
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2013
by , , , , , , ,  and
Mar. Drugs 2013, 11(11), 4464-4477; doi:10.3390/md11114464
Received: 11 September 2013 / Revised: 12 October 2013 / Accepted: 12 October 2013 / Published: 11 November 2013
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by , , , ,  and
Mar. Drugs 2013, 11(3), 747-774; doi:10.3390/md11030747
Received: 17 December 2012 / Revised: 28 January 2013 / Accepted: 6 February 2013 / Published: 11 March 2013
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2012
by , , , , , , ,  and
Mar. Drugs 2012, 10(11), 2560-2570; doi:10.3390/md10112560
Received: 20 August 2012 / Revised: 25 October 2012 / Accepted: 6 November 2012 / Published: 13 November 2012
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by , , ,  and
Mar. Drugs 2012, 10(10), 2138-2152; doi:10.3390/md10102138
Received: 17 August 2012 / Revised: 10 September 2012 / Accepted: 13 September 2012 / Published: 25 September 2012
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2011
by ,  and
Mar. Drugs 2011, 9(12), 2572-2604; doi:10.3390/md9122572
Received: 10 October 2011 / Revised: 18 November 2011 / Accepted: 22 November 2011 / Published: 8 December 2011
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by , , , , , , , ,  and
Mar. Drugs 2011, 9(11), 2188-2200; doi:10.3390/md9112188
Received: 14 September 2011 / Revised: 17 October 2011 / Accepted: 24 October 2011 / Published: 2 November 2011
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by ,  and
Mar. Drugs 2011, 9(10), 1914-1954; doi:10.3390/md9101914
Received: 3 August 2011 / Revised: 7 September 2011 / Accepted: 13 September 2011 / Published: 14 October 2011
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by
Mar. Drugs 2011, 9(10), 1731-1760; doi:10.3390/md9101731
Received: 26 August 2011 / Revised: 22 September 2011 / Accepted: 26 September 2011 / Published: 30 September 2011
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by , , , , , , , ,  and
Mar. Drugs 2011, 9(9), 1664-1681; doi:10.3390/md9091664
Received: 22 July 2011 / Revised: 2 September 2011 / Accepted: 5 September 2011 / Published: 23 September 2011
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by
Mar. Drugs 2011, 9(9), 1510-1533; doi:10.3390/md9091510
Received: 26 July 2011 / Revised: 28 August 2011 / Accepted: 31 August 2011 / Published: 9 September 2011
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by , ,  and
Mar. Drugs 2011, 9(6), 1038-1055; doi:10.3390/md9061038
Received: 1 May 2011 / Revised: 25 May 2011 / Accepted: 7 June 2011 / Published: 14 June 2011
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2010
by , , , , , ,  and
Mar. Drugs 2010, 8(9), 2480-2492; doi:10.3390/md8092480
Received: 22 July 2010 / Revised: 30 August 2010 / Accepted: 3 September 2010 / Published: 6 September 2010
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by
Mar. Drugs 2010, 8(9), 2435-2465; doi:10.3390/md8092435
Received: 22 July 2010 / Revised: 19 August 2010 / Accepted: 20 August 2010 / Published: 2 September 2010
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by , , , , ,  and
Mar. Drugs 2010, 8(8), 2240-2251; doi:10.3390/md8082240
Received: 8 June 2010 / Revised: 16 July 2010 / Accepted: 28 July 2010 / Published: 30 July 2010
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by , , , , ,  and
Mar. Drugs 2010, 8(7), 2038-2064; doi:10.3390/md8072038
Received: 13 May 2010 / Revised: 11 June 2010 / Accepted: 28 June 2010 / Published: 1 July 2010
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by ,  and
Mar. Drugs 2010, 8(6), 1779-1802; doi:10.3390/md8061779
Received: 8 May 2010 / Revised: 25 May 2010 / Accepted: 2 June 2010 / Published: 3 June 2010
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by , , , , ,  and
Mar. Drugs 2010, 8(6), 1763-1768; doi:10.3390/md8061763
Received: 15 April 2010 / Revised: 14 May 2010 / Accepted: 26 May 2010 / Published: 28 May 2010
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Last update: 1 April 2015

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