Next Article in Journal
Silaffins in Silica Biomineralization and Biomimetic Silica Precipitation
Next Article in Special Issue
Alginate-Derived Oligosaccharide Inhibits Neuroinflammation and Promotes Microglial Phagocytosis of β-Amyloid
Previous Article in Journal
Are the Traditional Medical Uses of Muricidae Molluscs Substantiated by Their Pharmacological Properties and Bioactive Compounds?
Previous Article in Special Issue
Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2015, 13(8), 5276-5296; doi:10.3390/md13085276

The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes

1
Institute for Marine Coastal Environment (Unit of Taranto), National Research Council (IAMC-CNR) Via Roma 3, 74100 Taranto, Italy
2
Department of Biological and Environmental Sciences and Technologies (DiSTeBA), Università del Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy
3
Lachifarma s.r.l., S.S.16 Zona Industriale, Zollino (Le) 73010, Italy
4
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), Università di Palermo, Via Archirafi, 18, 90123 Palermo, Italy
5
National Interuniversity Consortium for Marine Sciences (CoNISMa), Local Research Unit Lecce, Lecce 73100, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Paola Laurienzo
Received: 16 June 2015 / Revised: 27 July 2015 / Accepted: 6 August 2015 / Published: 19 August 2015
(This article belongs to the Collection Marine Polysaccharides)
View Full-Text   |   Download PDF [1074 KB, uploaded 19 August 2015]   |  

Abstract

The mucus produced by many marine organisms is a complex mixture of proteins and polysaccharides forming a weak watery gel. It is essential for vital processes including locomotion, navigation, structural support, heterotrophic feeding and defence against a multitude of environmental stresses, predators, parasites, and pathogens. In the present study we focused on mucus produced by a benthic cnidarian, the sea anemone Actinia equina (Linnaeus, 1758) for preventing burial by excess sedimentation and for protection. We investigated some of the physico-chemical properties of this matrix such as viscosity, osmolarity, electrical conductivity, protein, carbohydrate, and total lipid contents. Some biological activities such as hemolytic, cytotoxic, and antibacterial lysozyme-like activities were also studied. The A. equina mucus is mainly composed by water (96.2% ± 0.3%), whereas its dry weight is made of 24.2% ± 1.3% proteins and 7.8% ± 0.2% carbohydrates, with the smallest and largest components referable to lipids (0.9%) and inorganic matter (67.1%). The A. equina mucus matrix exhibited hemolytic activity on rabbit erythrocytes, cytotoxic activity against the tumor cell line K562 (human erythromyeloblastoid leukemia) and antibacterial lysozyme-like activity. The findings from this study improve the available information on the mucus composition in invertebrates and have implications for future investigations related to exploitation of A. equina and other sea anemones’ mucus as a source of bioactive compounds of high pharmaceutical and biotechnological interest. View Full-Text
Keywords: mucus; Actinia equina; antibacterial activity; hemolytic activity; cytotoxicity; tumor cell line K562 mucus; Actinia equina; antibacterial activity; hemolytic activity; cytotoxicity; tumor cell line K562
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Stabili, L.; Schirosi, R.; Parisi, M.G.; Piraino, S.; Cammarata, M. The Mucus of Actinia equina (Anthozoa, Cnidaria): An Unexplored Resource for Potential Applicative Purposes. Mar. Drugs 2015, 13, 5276-5296.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top