Next Article in Journal
High-Value Components and Bioactives from Sea Cucumbers for Functional Foods—A Review
Next Article in Special Issue
The Structural Diversity of Carbohydrate Antigens of Selected Gram-Negative Marine Bacteria
Previous Article in Journal
Seasonal Dynamics of Microcystis spp. and Their Toxigenicity as Assessed by qPCR in a Temperate Reservoir
Previous Article in Special Issue
Marine Polysaccharides: A Source of Bioactive Molecules for Cell Therapy and Tissue Engineering
Mar. Drugs 2011, 9(10), 1731-1760; doi:10.3390/md9101731

Therapies from Fucoidan; Multifunctional Marine Polymers

Marinova Pty Ltd., 249 Kennedy Drive, Cambridge, Tasmania 7170, Australia
Received: 26 August 2011 / Revised: 22 September 2011 / Accepted: 26 September 2011 / Published: 30 September 2011
(This article belongs to the collection Marine Polysaccharides)
View Full-Text   |   Download PDF [266 KB, uploaded 24 February 2015]


Published research on fucoidans increased three fold between 2000 and 2010. These algal derived marine carbohydrate polymers present numerous valuable bioactivities. This review discusses the role for fucoidan in the control of acute and chronic inflammation via selectin blockade, enzyme inhibition and inhibiting the complement cascade. The recent data on toxicology and uptake of fucoidan is detailed together with a discussion on the comparative activities of fractions of fucoidan from different sources. Recent in vivo, in vitro and clinical research related to diverse clinical needs is discussed. Targets include osteoarthritis, kidney and liver disease, neglected infectious diseases, hemopoietic stem cell modulation, protection from radiation damage and treatments for snake envenomation. In recent years, the production of well characterized reproducible fucoidan fractions on a commercial scale has become possible making therapies from fucoidan a realizable goal.
Keywords: fucoidan; inflammation; fibrosis; viral infection fucoidan; inflammation; fibrosis; viral infection
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Fitton, J.H. Therapies from Fucoidan; Multifunctional Marine Polymers. Mar. Drugs 2011, 9, 1731-1760.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert