Special Issue "Neuroprotective Strategies 2014"
Deadline for manuscript submissions: closed (31 July 2014)
Prof. Dr. Katalin Prokai-Tatrai
Center for Neuroscience Discovery, Department of Pharmaceutical Sciences, University of North Texas; Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA
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Interests: medicinal chemistry: drug design of central nervous system agents; neuropeptides and peptidomimetics; prodrugs for CNS delivery; oxidative stress; estrogens and other phenolic antioxidants; protein carbonylationmedicinal chemistry: drug design of central nervous system agents; neuropeptides and peptidomimetics; prodrugs for CNS delivery; oxidative stress; estrogens and other phenolic antioxidants; protein carbonylation
We started the “Neuroprotective Strategies“ special issue jointly with Molecules first in 2009. It was a great success; a large number of reviews and original research articles were published in the inaugural volumes. Since then, the International Journal of Molecular Sciences has successfully continued this special issue covering neuroprotection broadly including, but not limited to, preclinical/basic science assessments of various animal models relevant to diseases and agents with potential or perceived translation values. Due to the lack of successful clinical realizations of otherwise attractive preclinical data, we open up “Neuroprotective Strategies 2013” to thought-provoking Comments, Opinions and Perspectives, in addition to our traditional Reviews and Research Articles. We especially encourage submissions that address critical issues having prevented successful translations of promising laboratory data, such as limitations of in vitro studies and preclinical animal models to mirror multiple pathologies underlying human neurodegenerative diseases, lack of drug-likeness of experimental agents, the need to consider absorption, distribution, metabolism, elimination, toxicology (ADMET) and pharmacokinetics even in the early stage of drug discovery, as well as obstacles of drug delivery to the CNS. Critical reviews on relevant patent literature are also welcome. I give thanks for past contributions and look forward to your submissions on the promising and challenging aspects of the field.
Dr. Katalin Prokai-Tatrai
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- age-related neurodegeneration
- blood-brain barrier;
- CNS injury;
- cognition and dementia;
- drug delivery and drug-likeness;
- in silico drug design and disease models;
- ischemia and reperfusion;
- oxidative stress;
- peripheral nervous system;
- stem cell;
- structure-activity relationship;
- translational medicine