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Int. J. Mol. Sci. 2014, 15(3), 3533-3545; doi:10.3390/ijms15033533

Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits

Eulerweg 4, D-64347 Griesheim, Germany
Received: 25 December 2013 / Revised: 30 January 2014 / Accepted: 13 February 2014 / Published: 26 February 2014
(This article belongs to the Special Issue Neuroprotective Strategies 2014)
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A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, and application of smoked and nitrate/nitrite-cured meat products in the diet during circumscribed time intervals. The biological mechanisms might involve a break of tolerance by an alteration of self within the central nervous system, by nitrophenylated compounds conjugated to animal tissue, in particular to proteins occurring in the central nervous system. Further research is needed.
Keywords: multiple sclerosis; epidemiology; diet; meat; nitrophenols multiple sclerosis; epidemiology; diet; meat; nitrophenols
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Lauer, K. Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits. Int. J. Mol. Sci. 2014, 15, 3533-3545.

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