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Int. J. Mol. Sci. 2014, 15(10), 19226-19238; doi:10.3390/ijms151019226

Stem Cell Treatment for Alzheimer’s Disease

1
Department of Stem Cell Disorders, Kansai Medical University, 2-5-1 Shinmachi, Hirakata City, Osaka 573-1010, Japan
2
Department of Cardiac Surgery, Beijing Institute of Heart, Lung & Blood Vessel Disease, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing 100029, China
*
Author to whom correspondence should be addressed.
Received: 6 September 2014 / Revised: 9 October 2014 / Accepted: 10 October 2014 / Published: 23 October 2014
(This article belongs to the Special Issue Neuroprotective Strategies 2014)
View Full-Text   |   Download PDF [1231 KB, uploaded 23 October 2014]   |  

Abstract

Alzheimer’s disease (AD) is a progressive and neurodegenerative disorder that induces dementia in older people. It was first reported in 1907 by Alois Alzheimer, who characterized the disease as causing memory loss and cognitive impairment. Pathologic characteristics of AD are β-amyloid plaques, neurofibrillary tangles and neurodegeneration. Current therapies only target the relief of symptoms using various drugs, and do not cure the disease. Recently, stem cell therapy has been shown to be a potential approach to various diseases, including neurodegenerative disorders, and in this review, we focus on stem cell therapies for AD. View Full-Text
Keywords: Alzheimer’s disease; stem cell therapy; oxidative stress; neurodegeneration Alzheimer’s disease; stem cell therapy; oxidative stress; neurodegeneration
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Li, M.; Guo, K.; Ikehara, S. Stem Cell Treatment for Alzheimer’s Disease. Int. J. Mol. Sci. 2014, 15, 19226-19238.

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