Topic Editors

Prof. Dr. Yongbin Han
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
Dr. Yan Xu
College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China
Dr. Ting Wang
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Sustainable Alternative Proteins: Extraction, Modification and Food System Application

Abstract submission deadline
1 February 2027
Manuscript submission deadline
30 April 2027
Viewed by
549

Topic Information

Dear Colleagues,

The global food system is facing unprecedented challenges from population growth, climate change, and resource constraints. The development of sustainable alternative proteins—including plant-based proteins, microbial proteins, insect proteins, and proteins recovered from agricultural and food processing byproducts, such as whey protein and rapeseed protein—has emerged as a critical strategy to improve food security, reduce environmental impact, and meet the growing demand for high-quality protein from a global population projected to reach 9.7 billion by 2050.

While alternative proteins offer promising environmental and nutritional benefits, their widespread application in the food system faces multiple technical bottlenecks: low extraction efficiency from raw materials; unfavorable functional properties (e.g., solubility, emulsification, gelling); off-flavor issues; inconsistent retention of bioactive components during processing; lack of standardized nutritional evaluation frameworks for complex alternative protein products; as well as unclear long-term health effects and dose–response relationships of alternative protein consumption. This Topic aims to gather cutting-edge research on the entire value chain of sustainable alternative proteins, from green extraction technologies, nutritional property optimization, and health effect validation to functional modification strategies and end-product application in complex food systems, providing a multidisciplinary platform for researchers to share advances in this rapidly growing field.

We invite original research papers and review articles covering, but not limited to, the following topics:

  • Exploration and characterization of novel alternative protein sources (plant, microbial, insect, marine and byproduct-derived proteins);
  • Green and efficient protein extraction technologies (pulsed electric field, ultrasound-assisted, enzyme-assisted and supercritical fluid extraction);
  • Physical, chemical and biological modification technologies to improve the functional and nutritional properties of alternative proteins;
  • Approaches to the complete or partial replacement of proteins contained in traditional animal products (e.g., sausages, hams, dairy products);
  • Structure–function relationship studies of modified alternative proteins;
  • Nutritional profile characterization and comparative analysis of different types of alternative proteins;
  • Health benefit evaluation of alternative protein consumption, including effects on weight management, gut microbiota, metabolic syndrome, and chronic disease prevention;
  • Application of alternative proteins in food systems (plant-based meat, dairy alternatives, baked goods, nutritional supplements, etc.);
  • Sensory evaluation, consumer acceptance, and market analysis of alternative protein products.

Prof. Dr. Yongbin Han
Dr. Chong Xie
Dr. Yan Xu
Dr. Ting Wang
Topic Editors

Keywords

  • proteins
  • sustainability
  • extraction
  • functional modification
  • alternative proteins
  • marine proteins
  • bioavailability
  • fermentation
  • plant-based proteins
  • insects
  • byproduct valorization
  • nutritional properties
  • gut microbiota
  • consumer acceptance

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Beverages
beverages
3.0 4.7 2015 23.7 Days CHF 1800 Submit
Dairy
dairy
3.0 5.4 2020 26.6 Days CHF 1400 Submit
Foods
foods
6.0 10.3 2012 15 Days CHF 2900 Submit
Nutrients
nutrients
5.8 10.2 2009 15 Days CHF 2900 Submit
Sci
sci
4.1 5.4 2019 26.7 Days CHF 1400 Submit
Sustainability
sustainability
4.1 8.9 2009 17.9 Days CHF 2400 Submit

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Published Papers (1 paper)

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17 pages, 5292 KB  
Article
Purification of Protein Glutaminase by Cell Surface Display and Krill Protein Modification via Deamidation
by Jiacheng Zhang, Yu Zhang, Ting Wang, Xu Li, Xiujuan An and Chong Zhang
Foods 2026, 15(12), 2107; https://doi.org/10.3390/foods15122107 - 11 Jun 2026
Viewed by 161
Abstract
In this study, a novel protein glutaminase derived from Chryseobacterium lactis CGMCC 33780 (CLPG) was successfully purified via a one-step cell surface display approach, yielding its mature form. Subsequently, the enzymatic properties of CLPG were characterized. It exhibited optimal activity at a pH [...] Read more.
In this study, a novel protein glutaminase derived from Chryseobacterium lactis CGMCC 33780 (CLPG) was successfully purified via a one-step cell surface display approach, yielding its mature form. Subsequently, the enzymatic properties of CLPG were characterized. It exhibited optimal activity at a pH of 5 and a reaction temperature of 50 °C, and retained over 70% of its activity after a 12 h incubation at 50 °C. The study further investigated the impact of CLPG-mediated deamidation on the structural and functional attributes of krill protein isolate (KPI). A comprehensive analysis was conducted on the deamidation extent, conformational alterations, and microstructural morphology of KPI, employing techniques such as FTIR, CD, DSC, and SEM. After deamidation treatment with CLPG, the foaming and emulsifying properties of KPI were moderately shifted. When the CLPG dosage was 1.0 U/g with a corresponding deamidation degree of 15.18%, the emulsifying property of KPI reached the maximum value of 23%. These property enhancements were possibly primarily attributed to the increased electrostatic repulsion and hydrophobicity induced during the deamidation process. This work not only pioneers a novel method for the expression and purification of protein glutaminase but also applies it to the modification of krill protein, offering fresh insights for the development and application of protein glutaminases. Full article
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