Muscle Aging and Sarcopenia: Mechanisms, Metabolic Regulation, and Intervention Strategies

Topic Information

Dear Colleagues,

The aging process is accompanied by a progressive deterioration in the structure and function of the skeletal muscle system. This scenario is concerning, mainly among older adults, because it increases the risk of major clinical conditions, including frailty, disability, falls, hospitalization, nursing-home placement, reduced quality of life, and death. Despite significant advances, the cellular and molecular mechanisms underlying these physiopathological modifications remain incompletely understood. To add evidence to the literature, this Topic aims to integrate current knowledge and emerging evidence on the biological processes underlying muscle deterioration, including mitochondrial dysfunction, chronic low-grade inflammation, oxidative stress, impaired proteostasis, altered muscle regeneration, and neurological and nutritional factors. Particular emphasis will be placed on the interplay between myofibers, satellite cells, vascular function, and systemic metabolic alterations. Contributions exploring molecular and cellular pathways, biomarkers, experimental models, and therapeutic strategies are welcome. By integrating basic and translational research, this Topic seeks to advance understanding of age-related muscle deterioration and promote the development of effective preventive and regenerative interventions.

Dr. Hélio José Coelho Júnior
Dr. Mariam El Assar
Dr. Javier Angulo
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Antioxidants antioxidants	6.6	12.4	2012	18.7 Days	CHF 2900	Submit
Biomedicines biomedicines	3.9	6.8	2013	21 Days	CHF 2600	Submit
Biomolecules biomolecules	4.8	9.2	2011	17.9 Days	CHF 2700	Submit
Cells cells	5.2	10.5	2012	15.5 Days	CHF 2700	Submit
International Journal of Molecular Sciences ijms	4.9	9.0	2000	17.8 Days	CHF 2900	Submit
Metabolites metabolites	3.7	6.9	2011	16.7 Days	CHF 2700	Submit
Nutrients nutrients	5.0	9.1	2009	15 Days	CHF 2900	Submit
Sci sci	-	5.2	2019	26.7 Days	CHF 1400	Submit

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