Exercise and Chronic Disease

Dear Colleagues,

The Topic ‘Exercise and Chronic Disease’ is open for submissions. It is well established that among all the different strategies aimed at improving overall health, exercise is by far the most cost-effective. Exercise brings a plethora of physiological changes that improve general health status, reducing all-cause mortality. The positive effects of exercise can also be observed in patients with chronic disease. Exercise has been proved as an effective “medicine” for the prevention and treatment of multiple chronic diseases (musculoskeletal, metabolic, cardiovascular, respiratory, nervous system diseases, cancer, etc.). For this Topic, we encourage researchers to submit high-quality observational, experimental, and review studies that provide evidence about the benefits of exercise in chronic disease. Randomized controlled trials evaluating the effectiveness of exercise interventions, longitudinal cohort studies, or systematic reviews with meta-analyses are specially welcomed. Furthermore, it is of particular interest for us to receive articles trying to develop robust designs that improve the existing literature and that are committed to either dose–response analyses or causal inference examining in depth to what extent physical activity and exercise have a causal effect on preventing or treating chronic disease and improving health.

Dr. Joaquín Calatayud
Dr. Rubén López-Bueno
Topic Editors