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MDPIMDPI

9 Results Found

  • Brief Report
  • Open Access
3 Citations
4,590 Views
8 Pages
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Evaluation of the Abbott Alinity i Thyroid-Stimulating Hormone Receptor Antibody (TRAb) Chemiluminescent Microparticle Immunoassay (CMIA)

  • Deborah J. W. Lee,
  • Soon Kieng Phua,
  • Yali Liang,
  • Claire Chen and
  • Tar-Choon Aw
Diagnostics2023, 13(16), 2707;https://doi.org/10.3390/diagnostics13162707

19 August 2023

Background: We evaluated the performance of the Abbott thyroid-stimulating hormone receptor antibody chemiluminescent microparticle immunoassay (CMIA) on the Alinity i. Methods: Verification studies for precision, linearity, analytical measuring rang...

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  • Case Report
  • Open Access
4 Citations
5,889 Views
10 Pages
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Fetal Hyperthyroidism with Maternal Hypothyroidism: Two Cases of Intrauterine Therapy

  • Lu Hong,
  • Mary Hoi Yin Tang,
  • Ka Wang Cheung,
  • Libing Luo,
  • Cindy Ka Yee Cheung,
  • Xiaoying Dai,
  • Yanyan Li,
  • Chuqin Xiong,
  • Wei Liang and
  • Shengmou Lin
  • + 3 authors
Diagnostics2024, 14(1), 102;https://doi.org/10.3390/diagnostics14010102

3 January 2024

Fetal hyperthyroidism can occur secondary to maternal autoimmune hyperthyroidism. The thyroid-stimulating hormone receptor antibody (TRAb) transferred from the mother to the fetus stimulates the fetal thyroid and causes fetal thyrotoxicosis. Fetuses...

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  • Article
  • Open Access
3 Citations
5,850 Views
10 Pages
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Timing of Graves’ Hyperthyroidism Management in Pregnant Women: Impact on the Infant Thyroid Volume

  • Aleksandra Mikołajczak and
  • Renata Bokiniec
Nutrients2022, 14(9), 1972;https://doi.org/10.3390/nu14091972

9 May 2022

The thyroid of the fetus of a mother with Graves’ disease (GD) is affected by the transplacental passage of both antithyroid drugs (ATDs) and thyroid-stimulating hormone receptor antibodies (TRAb). Thyroid hormone imbalances are harmful for the...

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  • Article
  • Open Access
1,472 Views
11 Pages
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Reference Intervals and Cut-Off Values for Thyroid Tests in the Croatian Adult Population on the Snibe MAGLUMI X6 Immunoassay Analyzer

  • Ivana Lapić,
  • Dragana Šegulja,
  • Željkica Jakoplić,
  • Iva Lukić and
  • Dunja Rogić
Diagnostics2025, 15(18), 2360;https://doi.org/10.3390/diagnostics15182360

17 September 2025

Background/Objectives: To establish reference intervals (RIs) and cut-off values for thyroid-related tests on the MAGLUMI X6 immunoassay analyzer (Snibe Diagnostic, Shenzhen, China) in an adult Croatian population. Methods: This study included 305 he...

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  • Article
  • Open Access
1 Citations
4,722 Views
13 Pages
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K-Means Clustering Reveals Long-Term Thyrotropin Receptor Antibody Patterns in Graves’ Disease: Insights from a 10-Year Study with Implications for Graves’ Orbitopathy

  • Jungyul Park,
  • Jae Hyun Kim,
  • Hee-young Choi,
  • Jinmi Kim,
  • Sang Soo Kim and
  • Suk-woo Yang
J. Clin. Med.2025, 14(5), 1734;https://doi.org/10.3390/jcm14051734

4 March 2025

Background/Objectives: We aimed to explore long-term trajectories of thyroid-stimulating hormone receptor antibody (TRAb) in patients with Graves’ disease (GD) and to identify key factors associated with TRAb normalization. We also investigated...

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  • Article
  • Open Access
2 Citations
5,030 Views
12 Pages
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Evaluation of Anti-Thyroperoxidase (A-TPO) and Anti-Thyroglobulin (A-Tg) Antibodies in Women with Previous Hashimoto’s Thyroiditis during and after Pregnancy

  • Maria Angela Zaccarelli-Marino,
  • Nuha Ahmad Dsouki,
  • Rodrigo Pigozzi de Carvalho and
  • Rui M. B. Maciel
J. Clin. Med.2024, 13(15), 4519;https://doi.org/10.3390/jcm13154519

2 August 2024

Background/Objective: Autoimmune thyroid diseases (AITD) affect 2 to 5% of the general population. This study aimed to determine changes in activity of A-Tg and A-TPO antibodies before, during, and after pregnancy in women with previous AITD. Methods...

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  • Case Report
  • Open Access
1 Citations
994 Views
11 Pages
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New-Onset Graves’ Ophthalmopathy After Treatment with Pembrolizumab: A Case Report and a Review of the Literature

  • Moduo Pan,
  • Xuecong Zhou and
  • Yuan Wu
Diagnostics2025, 15(21), 2764;https://doi.org/10.3390/diagnostics15212764

31 October 2025

Background and Clinical Significance: Immune checkpoint inhibitors (ICIs), a revolutionary class of oncology therapeutics that enhance T cell-mediated antitumor immunity, are associated with various immune-related adverse events (IRAEs). While destru...

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  • Article
  • Open Access
1,544 Views
14 Pages
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Non-Thyroidal Illness Syndrome and Thyroid Autoimmunity in Hospitalized COVID-19 Patients: A Retrospective Study

  • Ewa Kozłowska,
  • Milena Małecka-Giełdowska and
  • Olga Ciepiela
J. Clin. Med.2025, 14(19), 6784;https://doi.org/10.3390/jcm14196784

25 September 2025

Background: Thyroid dysfunction, including non-thyroidal illness syndrome (NTIS), is commonly observed in critically ill patients and has been reported in COVID-19, particularly in those with severe disease. NTIS is defined by low free triiodothyroni...

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  • Review
  • Open Access
4 Citations
4,375 Views
9 Pages
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Liver Dysfunction in a Patient with Graves’ Disease

  • Filipa Campos,
  • Angelica Sharma,
  • Bijal Patel,
  • Deborah Papadopoulou,
  • Alexander N. Comninos and
  • Ali Abbara
J. Clin. Med.2024, 13(22), 6968;https://doi.org/10.3390/jcm13226968

19 November 2024

Liver dysfunction can occur in patients presenting with thyrotoxicosis, due to several different aetiologies. A 42-year-old man had mild liver dysfunction on presentation with hyperthyroidism due to Graves’ disease (GD): ALT 65 (0–45 IU/L...

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