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1,920 Results Found

  • Systematic Review
  • Open Access
13 Citations
8,060 Views
22 Pages

Species-Specific Sensitivity and Levels of Beta-D-Glucan for the Diagnosis of Candidemia—A Systematic Review and Meta-Analysis

  • Nadir Ullah,
  • Marco Muccio,
  • Laura Magnasco,
  • Chiara Sepulcri and ,
  • Daniele Roberto Giacobbe,
  • Antonio Vena,
  • Matteo Bassetti and
  • Malgorzata Mikulska
  • + 3 authors+ 0 author

15 February 2025

Background: 1, 3-ß-D-Glucan (BDG) is an antigen present in the cell wall of many pathogenic fungi and is used as a marker for the early diagnosis of candidemia and discontinuation of empirical treatment. Changes in the epidemiology of Candida s...

(This article belongs to the Collection Invasive Candidiasis)
  • Article
  • Open Access
1 Citations
1,662 Views
11 Pages

28 January 2026

Dermatophytes are fungi that infect the human skin and its appendages. With new pathogenic species emerging and resistance to first-line drugs rising, microbiologic diagnosis and species identification are becoming even more important. In this study,...

(This article belongs to the Section Fungal Pathogenesis and Disease Control)
  • Article
  • Open Access
10 Citations
6,869 Views
12 Pages

Evaluation of the Performance of Rapid Diagnostic Tests for Malaria Diagnosis and Mapping of Different Plasmodium Species in Mali

  • Pascal Dembélé,
  • Mady Cissoko,
  • Adama Zan Diarra,
  • Lassana Doumbia and ,
  • Aïssata Koné,
  • Mahamadou H. Magassa,
  • Maissane Mehadji,
  • Mahamadou A. Thera and
  • Stéphane Ranque
  • + 4 authors+ 0 author

Background: The first-line diagnosis of malaria in Mali is based on the use of rapid diagnostic tests (RDT) that detect the Histidin Rich Protein 2 (HRP2) antigen specific to Plasmodium falciparum. Our study, based on a real-time polymerase chain rea...

  • Article
  • Open Access
17 Citations
5,860 Views
10 Pages

Sputum Galactomannan Has Utility in the Diagnosis of Chronic Pulmonary Aspergillosis

  • Ali Nuh,
  • Newara Ramadan,
  • Anand Shah and
  • Darius Armstrong-James

14 February 2022

Diagnosis of pulmonary aspergillosis (PA), a fungal disease caused by Aspergillus species, is challenging since symptoms are unspecific. The galactomannan (antigen secreted by Aspergillus species) test in bronchoalveolar lavage (BAL) fluid is a valua...

(This article belongs to the Topic Infectious Diseases)
  • Article
  • Open Access
11 Citations
4,552 Views
13 Pages

Application of a Genus-Specific LAMP Assay for Schistosome Species to Detect Schistosoma haematobium x Schistosoma bovis Hybrids

  • Beatriz Crego-Vicente,
  • Pedro Fernández-Soto,
  • Begoña Febrer-Sendra,
  • Juan García-Bernalt Diego and ,
  • Jérôme Boissier,
  • Etienne K. Angora,
  • Ana Oleaga and
  • Antonio Muro
  • + 3 authors+ 0 author

22 March 2021

Schistosomiasis is a disease of great medical and veterinary importance in tropical and subtropical regions caused by different species of parasitic flatworms of the genus Schistosoma. The emergence of natural hybrids of schistosomes indicate the ris...

(This article belongs to the Special Issue Epidemiology, Immunology, and Control of Schistosomiasis)
  • Article
  • Open Access
10 Citations
5,016 Views
18 Pages

Senescence Marker Protein 30 (SMP30): A Novel Pan-Species Diagnostic Marker for the Histopathological Diagnosis of Breast Cancer in Humans and Animals

  • Su-Min Baek,
  • Seoung-Woo Lee,
  • Tae-Un Kim,
  • Seong-Kyoon Choi and ,
  • Sungho Yun,
  • Won-Jae Lee,
  • Se-Hyeon Han,
  • Il-Hwa Hong,
  • Sang-Joon Park and
  • Jin-Kyu Park
  • + 7 authors+ 2 authors

26 February 2021

Senescence marker protein 30 (SMP30) is a cell survival factor playing an important role in vitamin C synthesis and antiapoptosis. Moreover, its cytoprotective role suggests a possibility to be related to cancer cell survival. Mammary carcinoma is a...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Article
  • Open Access
3 Citations
2,540 Views
13 Pages

4 December 2020

This paper deals with the morphological and molecular characterization of Kochinema farodai Baqri and Bohra, 2001, with an integrative approach. The finding of K. faroidai in California is a remarkable biogeographical novelty, as it is the first Amer...

(This article belongs to the Section Veterinary Clinical Studies)
  • Review
  • Open Access
13 Citations
8,794 Views
18 Pages

Molecular Techniques and Target Selection for the Identification of Candida spp. in Oral Samples

  • Joana Magalhães,
  • Maria José Correia,
  • Raquel M. Silva,
  • Ana Cristina Esteves and ,
  • Artur Alves and
  • Ana Sofia Duarte
  • + 1 author+ 0 author

14 September 2022

Candida species are the causative agent of oral candidiasis, with medical devices being platforms for yeast anchoring and tissue colonization. Identifying the infectious agent involved in candidiasis avoids an empirical prescription of antifungal dru...

(This article belongs to the Special Issue Advanced Decision Making in Clinical Medicine)
  • Article
  • Open Access
8 Citations
4,063 Views
14 Pages

5 January 2023

Disporopsis longifolia Craib is an Asian medicinal plant belonging to the Asparagaceae family. The plants are well known for their steroidal saponins and phenolic compounds and are traditionally used as tonics for back pain, bellyache, cough, diabete...

(This article belongs to the Special Issue Medicinal Plants: Advances in Phytochemistry and Ethnobotany)
  • Article
  • Open Access
2 Citations
3,675 Views
12 Pages

Sensitivity Assessment of a Multiplex and Real-Time PCR Protocols for the Detection of Malaria in External Quality Control Samples in the Malaria Reference Center in Greece

  • Nikolaos Tegos,
  • Christos Goumenopoulos,
  • Anastasia Mpimpa,
  • Vasilios Papavasilopoulos and ,
  • Stavroula Beleri and
  • Eleni Patsoula
  • + 1 author+ 0 author

Background: Accurate malaria diagnosis constitutes a challenging task, necessitating the need for the implementation of targeted and effective diagnostic tools. The purpose of the current study was to evaluate the effectiveness of two different molec...

  • Review
  • Open Access
12 Citations
4,949 Views
25 Pages

Targeting Reactive Oxygen Species for Diagnosis of Various Diseases

  • Moung Young Lee,
  • Donguk Lee,
  • Dayun Choi,
  • Kye S. Kim and
  • Peter M. Kang

15 December 2024

Reactive oxygen species (ROS) are generated predominantly during cellular respiration and play a significant role in signaling within the cell and between cells. However, excessive accumulation of ROS can lead to cellular dysfunction, disease progres...

(This article belongs to the Section Biomaterials for Drug Delivery)
  • Article
  • Open Access
29 Citations
5,281 Views
10 Pages

Species-Specific Molecular Detection of the Root Knot Nematode Meloidogyne luci

  • Carla Maleita,
  • Joana M. S. Cardoso,
  • Leidy Rusinque,
  • Ivânia Esteves and
  • Isabel Abrantes

14 August 2021

Meloidogyne luci has been identified in various countries around the world parasitizing economically important crops and, due to its potential to cause serious damage to agriculture, was included in the European and Mediterranean Plant Protection Org...

(This article belongs to the Section Plant Science)
  • Article
  • Open Access
3 Citations
4,236 Views
12 Pages

Comparison of SD Bioline Malaria Ag Pf/Pan and Acro Malaria P.f./P.v./Pan with Microscopy and Real Time PCR for the Diagnosis of Human Plasmodium Species

  • Marylin Madamet,
  • Isabelle Fonta,
  • Joel Mosnier,
  • Nicolas Benoit and ,
  • Rémy Amalvict,
  • Sébastien Briolant,
  • French National Reference Centre for Imported Malaria Study Group and
  • Bruno Pradines
  • + 3 authors+ 0 author

The early diagnosis of malaria is crucial to controlling morbidity and mortality. The World Health Organization (WHO) recommends diagnosing malaria either using light microscopy or a malaria rapid diagnostic test (RDT). Most RDTs use antibodies to de...

(This article belongs to the Special Issue Laboratory Diagnosis in Microbial Diseases, 2nd Edition)
  • Article
  • Open Access
2 Citations
4,615 Views
13 Pages

Validation of a Real-Time PCR for the Diagnosis of Leishmania Species Using the Hsp20 Gene

  • Mayra Maldonado-Aroni,
  • Nyshon Rojas-Palomino,
  • Aide Sandoval-Juarez,
  • Marco Galarza-Pérez and ,
  • José Alarcón-Guerrero,
  • Rosa Guevara-Montero and
  • Víctor Cárdenas-López
  • + 2 authors+ 0 author

Leishmaniasis is a complex neglected tropical disease that impacts public health, particularly in resource-limited populations where access to accurate and timely diagnosis is often limited. Current diagnostic methods, primarily relying on microscopy...

(This article belongs to the Section Vector-Borne Diseases)
  • Article
  • Open Access
6 Citations
4,895 Views
11 Pages

Assessing Diagnosis of Candida Infections: A Study on Species Prevalence and Antifungal Resistance in Northern Morocco

  • Islam Ahaik,
  • Juan Carlos Nunez-Rodríguez,
  • Jamal Abrini,
  • Samira Bouhdid and
  • Toni Gabaldón

23 May 2024

The incidence of Candida infections has increased in the last decade, posing a serious threat to public health. Appropriately facing this challenge requires precise epidemiological data on species and antimicrobial resistance incidence, but many coun...

  • Article
  • Open Access
19 Citations
3,932 Views
11 Pages

29 September 2021

Molecular-based species identification tools are helpful to identify tiny insect and lepidopteran pests that show morphological similarities in the larval stage and are essential for quarantine as well as agricultural research. Here, we focused on fo...

  • Article
  • Open Access
17 Citations
4,766 Views
9 Pages

Diagnosis of Centrocestus formosanus Infection in Zebrafish (Danio rerio) in Italy: A Window to a New Globalization-Derived Invasive Microorganism

  • Antonino Pace,
  • Ludovico Dipineto,
  • Serena Aceto,
  • Maria Concetta Censullo and ,
  • Maria Carmen Valoroso,
  • Lorena Varriale,
  • Laura Rinaldi,
  • Lucia Francesca Menna,
  • Alessandro Fioretti and
  • Luca Borrelli
  • + 5 authors+ 0 author

9 March 2020

Centrocestus formosanus is a digenetic trematode with a complex life cycle, involving invertebrate and vertebrate hosts, humans included. In particular, it causes gill lesions and mortality in freshwater fish species, and gastrointestinal symptoms in...

(This article belongs to the Section Animal Physiology)
  • Review
  • Open Access
29 Citations
7,488 Views
61 Pages

Oxidative stress (OS), generated by the overrun of reactive species of oxygen and nitrogen (RONS), is the key cause of several human diseases. With inflammation, OS is responsible for the onset and development of clinical signs and the pathological h...

(This article belongs to the Special Issue The Role of Bioactive Compounds in Human Health and Disease: 2nd Edition)
  • Article
  • Open Access
18 Citations
4,784 Views
14 Pages

New Species-Specific Primers for Molecular Diagnosis of Bactrocera minax and Bactrocera tsuneonis (Diptera: Tephritidae) in China Based on DNA Barcodes

  • Linyu Zheng,
  • Yue Zhang,
  • Wenzhao Yang,
  • Yiying Zeng and ,
  • Fan Jiang,
  • Yujia Qin,
  • Jiafeng Zhang,
  • Zhaochun Jiang,
  • Wenzhao Hu and
  • Zhihong Li
  • + 9 authors+ 4 authors

12 December 2019

Tephritidae fruit flies (Diptera: Tephritidae) are regarded as important damage-causing species due to their ability to cause great economic losses in fruit and vegetable crops. Bactrocera minax and Bactrocera tsuneonis are two sibling species of the...

  • Article
  • Open Access
12 Citations
4,984 Views
16 Pages

A Simplified Multiplex PCR Assay for Simultaneous Detection of Six Viruses Infecting Diverse Chilli Species in India and Its Application in Field Diagnosis

  • Oinam Priyoda Devi,
  • Susheel Kumar Sharma,
  • Keithellakpam Sanatombi,
  • Konjengbam Sarda Devi and ,
  • Neeta Pathaw,
  • Subhra Saikat Roy,
  • Ngathem Taibangnganbi Chanu,
  • Rakesh Sanabam,
  • Huirem Chandrajini Devi and
  • Virendra Kumar Baranwal
  • + 6 authors+ 1 author

21 December 2022

Chilli is infected by at least 65 viruses globally, with a mixed infection of multiple viruses leading to severe losses being a common occurrence. A simple diagnostic procedure that can identify multiple viruses at once is required to track their spr...

(This article belongs to the Special Issue Emerging and Re-emerging Plant Viruses in a Context of Global Change)
  • Article
  • Open Access
8 Citations
4,653 Views
15 Pages

25 January 2023

Asian planthoppers (Hemiptera: Delphacidae) that include brown planthoppers (BPH, Nilaparvata lugens, Stål), white-backed planthoppers (WBPH, Sogatella furcifera, Horváth), and small brown planthoppers (SBPH, Laodelphax striatellus, Fall...

(This article belongs to the Section Insect Pest and Vector Management)
  • Brief Report
  • Open Access
27 Views
12 Pages

Cross-Species Evaluation of Mycobacterium tuberculosis Complex Molecular Diagnostic Kits for Human and Veterinary Use: Introducing the One Health Perspective into Laboratory Diagnosis

  • Ángel Sebastián Rodríguez-Pazmiño,
  • Bernardo Castro-Rodriguez,
  • Sarita Doménica Bautista-Arcentales,
  • Camilo Cárdenas Franco and ,
  • Jose Julian Zúñiga Velarde,
  • Solon Alberto Orlando,
  • Greta Franco-Sotomayor,
  • Natalia Jiménez Pizarro,
  • Estefanía Rosco Pizarro and
  • Miguel Angel Garcia-Bereguiain
  • + 6 authors+ 1 author

Background: Molecular assays for the Mycobacterium tuberculosis complex (MTBC) are validated and authorized separately for human and veterinary use, although they target conserved sequences of the same pathogen. This separation, driven by regulatory...

(This article belongs to the Special Issue Molecular Diagnostics for Tropical Infectious Diseases)
  • Editorial
  • Open Access
5 Citations
3,176 Views
6 Pages

24 November 2021

Tree pathogens and pests are fundamental components of forest ecosystems. By killing and decomposing susceptible trees, they regulate the cycle of nutrients and energy flow, thus shaping the structure and composition of forest stands. However, ecosys...

(This article belongs to the Special Issue Forest Pathology and Entomology)
  • Article
  • Open Access
38 Citations
5,420 Views
17 Pages

Species Detection within the Echinococcus granulosus sensu lato Complex by Novel Probe-Based Real-Time PCRs

  • Pavlo Maksimov,
  • Hannes Bergmann,
  • Marion Wassermann,
  • Thomas Romig and ,
  • Bruno Gottstein,
  • Adriano Casulli and
  • Franz J. Conraths
  • + 2 authors+ 0 author

26 September 2020

Infections with eggs of Echinococcus granulosus sensu lato (s.l.) can cause cystic echinococcosis in intermediate host animals and humans. Upon ingestion of viable eggs, oncospheres hatch from the eggs and subsequently develop into fluid-filled larva...

(This article belongs to the Special Issue Echinococcus)
  • Article
  • Open Access
4 Citations
3,021 Views
9 Pages

9 March 2023

Two new spider species of the genus Pholcus Walckenaer, 1805, Pholcus deokjeok sp. nov. and Pholcus gangneung sp. nov. in the family Pholcidae C. L. Koch, 1850 are newly described from South Korea. The present new species belong to the phun...

(This article belongs to the Special Issue Biodiversity and Conservation of Forests)
  • Article
  • Open Access
6 Citations
4,123 Views
12 Pages

Molecular Identification and Fungal Diversity Associated with Diseases in Hass Avocado Fruit Grown in Cauca, Colombia

  • Carolina Ángel-García,
  • Kevin Alejandro Rodríguez-Arevalo,
  • Nubia Murcia Riaño,
  • Luz Natalia Martínez-Caballero and ,
  • Germán Ceballos-Aguirre,
  • Alejandro Jaramillo Laverde and
  • Mauricio Fernando Martínez
  • + 2 authors+ 0 author

4 December 2023

Hass avocado fruit diseases are one of the main marketing constraints in Colombia. To identify and reveal the diversity of fungi associated with diseases in fruits and peduncles, symptomatic samples were collected from 67 farms in the 9 main Hass avo...

(This article belongs to the Section Fungal Pathogens)
  • Article
  • Open Access
19 Citations
6,641 Views
20 Pages

A New Duplex PCR-Assay for the Detection and Identification of Paracoccidioides Species

  • Breno Gonçalves Pinheiro,
  • Ana Paula Pôssa,
  • Paula Portella Della Terra,
  • Jamile Ambrósio de Carvalho and ,
  • Giannina Ricci,
  • Angela Satie Nishikaku,
  • Rosane Christine Hahn,
  • Zoilo Pires de Camargo and
  • Anderson Messias Rodrigues
  • + 4 authors+ 0 author

26 February 2021

Paracoccidioidomycosis (PCM) is a life-threatening systemic fungal infection caused by members of the Paracoccidioides brasiliensis complex and P. lutzii. Routine diagnoses of PCM down to the species level using classical mycological approaches are u...

(This article belongs to the Special Issue Paracoccidioides and Paracoccidioidomycosis)
  • Article
  • Open Access
2 Citations
3,004 Views
12 Pages

Polyclonal Antibody Generation against PvTRAg for the Development of a Diagnostic Assay for Plasmodium vivax

  • Shalini Aggarwal,
  • Selvamano Selvaraj,
  • Jayaprakash Nattamai Subramanian,
  • Mookambeswaran Arunachalam Vijayalakshmi and ,
  • Swati Patankar and
  • Sanjeeva Srivastava
  • + 1 author+ 0 author

22 February 2023

The World Health Organization (WHO) has set forth a global call for eradicating malaria, caused majorly by the protozoan parasites Plasmodium falciparum and Plasmodium vivax. The lack of diagnostic biomarkers for P. vivax, especially those that diffe...

(This article belongs to the Special Issue Novel Approaches for Diagnosis of Parasitic Disease)
  • Article
  • Open Access
2,662 Views
38 Pages

5 March 2024

The genus Trogolaphysa comprises 81 described species distributed across the Neotropical and Afrotropical regions. In the Americas, just over half of the species found in subterranean habitats have a reduced eye number (0–5 eyes). Subterranean...

  • Feature Paper
  • Article
  • Open Access
87 Views
24 Pages

24 October 2026

The genus Pseudophilothrips harbors Liothrips-like species in which seta S2 on the ninth abdominal segment in males is as long as seta S1. Thirteen species are included in the genus, most of which are restricted to Central and South America. During a...

(This article belongs to the Section Animal Taxonomy)
  • Article
  • Open Access
233 Views
41 Pages

MalarIA: A Modular AI-Powered Web Platform for Automated Plasmodium Species Classification from Blood Smear Microscopy

  • Francesco Branda,
  • Lilia Andriani,
  • Riccardo Lucis,
  • Riccardo Prete and ,
  • Annamaria Defilippo,
  • Ugo Lomoio,
  • Patrizia Vizza,
  • Giancarlo Ceccarelli,
  • Fabio Scarpa and
  • Pietro Hiram Guzzi
  • + 7 authors+ 2 authors

Background: Malaria continues to pose a significant global public health challenge, as reflected in the estimated 282 million cases and 610,000 associated deaths recorded worldwide in 2024. Elimination efforts are threatened by antimalarial drug resi...

(This article belongs to the Special Issue Advances in Tools for Battling Malaria)
  • Article
  • Open Access
22 Citations
4,665 Views
18 Pages

Efficiency of the CL, DRIS and CND Methods in Assessing the Nutritional Status of Eucalyptus spp. Rooted Cuttings

  • Thaís Chagas Barros de Morais,
  • Renato de Mello Prado,
  • Edilaine Istefani Franklin Traspadini,
  • Paulo Guilherme Salvador Wadt and ,
  • Rinaldo César de Paula and
  • Antônio Márcio Souza Rocha
  • + 1 author+ 0 author

9 September 2019

The efficiency of methods in adequately interpreting the nutritional status of Eucalyptus spp. rooted cuttings remains unknown. The aim was to evaluate the quality of diagnoses obtained using the critical level (CL), diagnosis and recommendation inte...

(This article belongs to the Section Forest Ecology and Management)
  • Article
  • Open Access
2 Citations
845 Views
15 Pages

9 July 2026

A group of freshwater species, i.e., Caridina gracilirostris, C. gracillima, C. neglecta, C. longifrons, C. wilsoni and C. leptopoda, widely distributed in the Indo–Pacific region, has been found to exhibit several distinct and unique morpholog...

(This article belongs to the Section Biodiversity and Functionality of Aquatic Ecosystems)
  • Review
  • Open Access
61 Citations
13,075 Views
17 Pages

Scedosporium and Lomentospora Infections: Contemporary Microbiological Tools for the Diagnosis of Invasive Disease

  • Sharon C.-A. Chen,
  • Catriona L. Halliday,
  • Martin Hoenigl,
  • Oliver A. Cornely and
  • Wieland Meyer

4 January 2021

Scedosporium/Lomentospora fungi are increasingly recognized pathogens. As these fungi are resistant to many antifungal agents, early diagnosis is essential for initiating targeted drug therapy. Here, we review the microbiological tools for the detect...

(This article belongs to the Special Issue Epidemiology, Diagnosis of Fungal Infections)
  • Article
  • Open Access
3 Citations
2,757 Views
9 Pages

Assessment of a Commercial Real-Time PCR Assay (Vitassay qPCR Malaria 5 Test) to Detect Human Malaria Infection in Travelers Returning to France

  • Marylin Madamet,
  • Rémy Amalvict,
  • Nicolas Benoit,
  • French National Reference Centre for Imported Malaria Study Group and
  • Bruno Pradines

10 November 2022

Malaria is the most common human parasitic disease in the world with the highest morbidity and mortality. Due to the severity of malaria caused by Plasmodium falciparum and the urgency of therapeutic management, quick and reliable diagnosis is requir...

(This article belongs to the Special Issue Diagnosis and Management of Malaria)
  • Article
  • Open Access
6 Citations
8,045 Views
17 Pages

Microarray for Identification of the Chiropteran Host Species of Rabies Virus in Canada

  • Oliver Lung,
  • Susan Nadin-Davis,
  • Mathew Fisher,
  • Anthony Erickson and ,
  • M. Kimberly Knowles,
  • Tara Furukawa-Stoffer and
  • Aruna Ambagala
  • + 2 authors+ 0 author

Species identification through genetic barcoding can augment traditional taxonomic methods, which rely on morphological features of the specimen. Such approaches are especially valuable when specimens are in poor condition or comprise very limited ma...

(This article belongs to the Special Issue Feature Papers)
  • Review
  • Open Access
1 Citations
1,842 Views
21 Pages

Infections and Syndromes Caused by Campylobacter

  • Cecilia Hernández-Cortez,
  • Andres Saldaña-Padilla,
  • Luis Fernando Muñoz-Mateo,
  • Luis Uriel Gonzalez-Avila and ,
  • Roger Orlando Medina-de-la-Cruz and
  • Graciela Castro-Escarpulli
  • + 1 author+ 0 author

In recent years, diseases caused by species of the genus Campylobacter have increased, due to improvements in identification methods, but also because, as part of global travel and trade, these species have spread to countries where no cases had prev...

(This article belongs to the Section Medical Microbiology)
  • Review
  • Open Access
47 Citations
10,583 Views
30 Pages

Trends in Molecular Diagnosis and Diversity Studies for Phytosanitary Regulated Xanthomonas

  • Vittoria Catara,
  • Jaime Cubero,
  • Joël F. Pothier,
  • Eran Bosis and ,
  • Claude Bragard,
  • Edyta Đermić,
  • Maria C. Holeva,
  • Marie-Agnès Jacques,
  • Francoise Petter and
  • Joana Costa
  • + 11 authors+ 6 authors

Bacteria in the genus Xanthomonas infect a wide range of crops and wild plants, with most species responsible for plant diseases that have a global economic and environmental impact on the seed, plant, and food trade. Infections by Xanthomonas spp. c...

(This article belongs to the Special Issue Integrating Science on Xanthomonas and Xylella for Integrated Plant Disease Management)
  • Review
  • Open Access
24 Citations
9,522 Views
18 Pages

Invasive Candidiasis in the Intensive Care Unit: Where Are We Now?

  • Jose A. Vazquez,
  • Lissette Whitaker and
  • Ana Zubovskaia

27 March 2025

Invasive fungal infections in the intensive care unit (ICU) are not uncommon and most cases are caused by Candida species, specifically Candida albicans. However, recently, there has been an increase in non-albicans Candida spp. (C. glabrata; C....

(This article belongs to the Special Issue Fungal Infections in Intensive Care Medicine)
  • Review
  • Open Access
27 Citations
5,706 Views
19 Pages

The Malignant Role of Exosomes as Nanocarriers of Rare RNA Species

  • Alina-Andreea Zimta,
  • Olafur Eysteinn Sigurjonsson,
  • Diana Gulei and
  • Ciprian Tomuleasa

15 August 2020

Nowadays, advancements in the oncology sector regarding diagnosis methods allow us to specifically detect an increased number of cancer patients, some of them in incipient stages. However, one of the main issues consists of the invasive character of...

(This article belongs to the Special Issue Exosomes in Cancer Diagnosis and Therapy)
  • Article
  • Open Access
7 Citations
3,106 Views
11 Pages

The Epidemiology of PCR-Confirmed Cutaneous Leishmaniasis in Israel: A Nationwide Study

  • Dror Avni,
  • Michal Solomon,
  • Merav Strauss,
  • Orli Sagi and ,
  • Violeta Temper,
  • Ayelet Michael-Gayego,
  • Tal Meningher,
  • Emily Avitan-Hersh,
  • Moran Szwarcwort-Cohen and
  • Eli Schwartz
  • + 7 authors+ 2 authors

Background: Leishmaniasis, mainly cutaneous leishmaniasis (CL), is endemic in Israel. In recent years, the diagnosis of leishmaniasis has transitioned to a molecular diagnosis. Objective: To summarize all cases of leishmaniasis and the identified spe...

(This article belongs to the Special Issue New Advancements in the Field of Leishmaniasis)
  • Review
  • Open Access
96 Citations
25,811 Views
30 Pages

Laboratory Diagnosis of Cutaneous and Visceral Leishmaniasis: Current and Future Methods

  • Juliana Quero Reimão,
  • Elizabeth Magiolo Coser,
  • Monica Ran Lee and
  • Adriano Cappellazzo Coelho

Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the detection and correct identification of the species of the parasite, mai...

(This article belongs to the Special Issue Identification of Microorganisms: Old, New and Future Methods)
  • Article
  • Open Access
8 Citations
4,700 Views
12 Pages

19 March 2021

The molecular detection of Candida plays an important role in the diagnosis of candidaemia, a major cause of morbidity and mortality. The sensitivity of this diagnosis is partly related to the efficiency of yeast DNA extraction. In this monocentric s...

  • Article
  • Open Access
7 Citations
3,018 Views
16 Pages

Combined Integrative RNA-Seq and Serological sIgE Analysis Enhances Understanding of Fish Allergen Profiles and Diagnostic Strategy for Fish Allergy

  • Zhong-Yi Liu,
  • Christine Yee Yan Wai,
  • Agnes Sze Yin Leung,
  • Wai Hung Chan and ,
  • Jaime Sou Rosa Duque,
  • Ivan Cheuk San Lam,
  • James Wesley Cheng,
  • Jason Ka Chun Sit,
  • Noelle Anne Ngai and
  • Ting Fan Leung
  • + 16 authors+ 11 authors

7 October 2024

Fish allergy is a significant health concern, with diagnosis and management complicated by diverse fish species and allergens. We conducted a comprehensive RNA-seq analysis of eight fish species to identify allergen profiles, integrating ImmunoCAP sI...

(This article belongs to the Special Issue Deciphering Allergies—Structural and Immunological Characterization of Allergenic Proteins and Immunomodulatory Agents)
  • Article
  • Open Access
42 Citations
7,801 Views
21 Pages

25 February 2019

Despite the fact that Candida albicans is documented to be the main cause of human candidiasis, non-C. albicans Candida (NCAC) species, such as Candida glabrata and Candida tropicalis, are also suggested to be implicated in the etiopathogenesis of op...

(This article belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
  • Brief Report
  • Open Access
24 Citations
3,818 Views
7 Pages

Sensitivity of Serum Beta-D-Glucan in Candidemia According to Candida Species Epidemiology in Critically Ill Patients Admitted to the Intensive Care Unit

  • Malgorzata Mikulska,
  • Laura Magnasco,
  • Alessio Signori,
  • Chiara Sepulcri and ,
  • Silvia Dettori,
  • Stefania Tutino,
  • Antonio Vena,
  • Franca Miletich,
  • Nadir Ullah and
  • Matteo Bassetti
  • + 10 authors+ 5 authors

30 August 2022

Serum beta-D-glucan (BDG) determination plays an important role in the diagnosis of candidemia among critically ill patients admitted to the intensive care unit (ICU). However, BDG levels measured may be lower in the case of infections caused by some...

(This article belongs to the Special Issue Medical Health Care and Human Fungi)
  • Review
  • Open Access
13 Citations
3,848 Views
10 Pages

14 October 2021

Nowadays, Plasmodium ovale is divided into two non-recombinant sympatric species: Plasmodium ovale wallikeri and Plasmodium ovale curtisi. In this mini review, we summarize the available knowledge on the clinical/biological aspects of P. ovale spp. m...

(This article belongs to the Special Issue Recent Advances in Malaria Diagnosis)
  • Article
  • Open Access
8 Citations
3,321 Views
15 Pages

An Integrated and Multi-Target Nucleic Acid Isothermal Analysis System for Rapid Diagnosis of Vulvovaginal Candidiasis

  • Xiangyu Jin,
  • Meng Li,
  • Zeyin Mao,
  • Anni Deng and ,
  • Wenqi Lv,
  • Leyang Huang,
  • Hao Zhong,
  • Han Yang,
  • Lei Zhang and
  • Guoliang Huang
  • + 6 authors+ 1 author

19 May 2023

Rapid identification of Candida species is significant for the diagnosis of vulvovaginal candidiasis (VVC). An integrated and multi-target system for the rapid, high-specificity, and high-sensitivity detection of four Candida species was developed. T...

(This article belongs to the Section Nano- and Micro-Technologies in Biosensors)
  • Article
  • Open Access
5 Citations
3,360 Views
13 Pages

24 February 2024

Staphylococcus schleiferi and Staphylococcus coagulans, closely related bacterial species within the Staphylococcus genus, present a challenge in classification and diagnosis due to their close genetic proximity and overlapping phenotypic features. M...

(This article belongs to the Section Microbial Genetics and Genomics)
  • Article
  • Open Access
5 Citations
4,835 Views
94 Pages

20 December 2019

The genus Downeshelea was described by Wirth and Grogan based on the diagnostic characters of the Monohelea multilineata species group. The first descriptions of species were based on body coloration, which resulted in confusion and misunderstanding...

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