Search Results (64)

Antimicrobial resistance arises from treatment non-adherence and ineffective delivery systems. Optimal wound dressings combine localized drug release, exudate management, and bacterial encapsulation through hydrogel-forming nanofibers for enhanced therapy. In this work, polylactic acid (PLA) and polyvinylpyrrolidone (PVP) fibers loaded with chlorhexidine (CHX) were developed using Solution Blow Spinning (SBS), a scalable electrospinning alternative that enables in situ deposition. Molecular interactions between CHX and polymers in solution (by UV-Vis and fluorescence spectroscopy) and in solid state (by FTIR, XRD and thermal analysis) were studied. The morphology of the polymeric fibers was determined by optical microscopy, showing that PVP fibers are thinner (1625 nm) and more uniform than those of PLA (2237 nm). Finally, drug release from single-polymer fibers discs, overlapping fibers discs (PLA/PVP/PLA and PVP/PLA/PVP), and solid dispersions was determined by UV-Vis spectrometry. PVP-based fibers exhibited faster CHX release due to their hydrophilic nature, while PLA fibers proved sustained release, attributed to their hydrophobic matrix. This study highlights the potential of PLA/PVP-CHX fibers made from SBS as advanced wound dressings, combining biocompatibility and personalized drug delivery, offering a promising platform for localized and controlled antibiotic delivery. Full article

Carbon dioxide (CO₂) capture is a pivotal technology for achieving the goal of carbon neutrality. This paper proposes a novel process, SBS + SI, which integrates Solution Blow Spinning (SBS) and Solution Impregnation Method (SI), using polyamide 66 (PA66) as the carrier material and high-purity tetraethylenepentamine (TEPA) as the modifier, to fabricate nanofiber adsorption membranes with varying carrier structures and modifier component loadings. The CO₂ adsorption performance and pore structure of the adsorbents were investigated using characterization techniques, such as Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Brunauer-Emmett-Teller (BET) surface area and pore size analysis, and Fourier Transform Infrared Spectroscopy (FT-IR). The results indicate that as the mass fraction of TEPA increases, the pores in the nanofiber membranes gradually decrease, while the CO₂ adsorption capacity significantly increases. The PA66 nanofiber membrane achieves peak CO₂ capture performance (44.7 mg/g at 25 °C) at 15% TEPA loading. Meanwhile, the composite nanofiber membranes also exhibit outstanding CO₂/N₂ selectivity with a separation factor reaching 28. Thermal regeneration tests at 90 °C confirm the composite’s outstanding cyclic stability and regenerability, demonstrating its potential for practical carbon capture applications. These findings suggest that the nanofiber adsorbents prepared by the SBS + SI process have broad application prospects in the field of CO₂ capture. Full article

Water is the most environmentally friendly solvent; however, conventional solution spinning using water as a solvent is challenging due to its low evaporation rate. We developed a double-pronged solution blow spinning (DP-SBS) system. This spinning technique significantly enhances solvent evaporation, and the designed structure (double-pronged) avoids the common problem of needle clogging caused by heating. DP-SBS enables high-yield production of water-soluble polymer nanofibers, with a production rate of up to 5.94 g/h, which far exceeds what can be achieved with traditional electrospinning or solution blow spinning. This method is also highly efficient for producing non-water-soluble polymer nanofibers, achieving a production rate of up to 7.91 g/h, the highest reported value to date. Additionally, this approach can be used to produce not only common two-dimensional fiber membranes but also fiber sponges in a single step using the double-pronged airflow system. For the first time, chitosan nanofiber sponges were successfully produced and demonstrated to have excellent hemostatic properties in medical hemostasis. This method can also be extended to the production of other 3D nanomaterials, such as mullite nanofiber sponges, which exhibit outstanding thermal insulation performance at high temperatures. Full article

Polyphenols are organic molecules extracted from various fruits, such as coffee and citrus, that possess biological activity and antioxidant properties. However, the presence of polyphenols in the environment is hazardous to water quality and living health. Among a variety of water remediation methods, adsorption remains a staple in the field. Therefore, this work aims to develop porous polycaprolactone: poly(methyl methacrylate) (PCL:PMMA) membranes as a support for hydrotalcite immobilization for the removal of chlorogenic acid polyphenol (CGA) from aqueous solutions. Due to the hydrophilic nature of hydrotalcite, the adsorbent was functionalized with hexadecyltrimethylammonium bromide (CTAB) to increase its affinity for CGA, resulting in a removal efficiency of approximately 96%. Composite fiber membranes were prepared by solution-blowing spinning with specific amounts of hydrotalcite added (i.e., 1 to 60 wt%). A 3:1 PCL:PMMA blend resulted in superior mechanical traction (0.8 MPa) and stress deformation (70%) compared to pure PCL (0.7 MPa and 37%) and PMMA (0.1 MPa and 5%) fibers. PCL:PMMA membranes with 60% LDH-CTAB exhibited CGA removal rates equal to 55% in the first cycle while maintaining the capacity to remove 30% of the polyphenol after five consecutive reuses. Removal rates up to 90% could also be achieved with an appropriate adsorbent dose (2 g L⁻¹). Adsorption was found to follow pseudo-second-order kinetics and was adequately described by the Langmuir model, saturating LDH-CTAB active sites in four hours. PCL:PMMA:LDH-CTAB composites can be considered a potential alternative to support adsorbents for water remediation. Full article

Currently, there is an increasing demand for advanced materials that can address the needs of tissue engineering and have the potential for use in treatments targeting tumor cells, such as black bioactive materials in photothermal therapy. Thus, 3D fibrous scaffolds of black 45S5 bioactive glass were produced using the air-heated solution blow spinning (A-HSBS) technique, with polyvinylpyrrolidone (PVP) serving as a spinning aid and an oxygen vacancy-inducing agent. Glass powder with the same composition was synthesized via the sol-gel route for comparison. The samples were characterized using thermogravimetric analysis, X-ray diffraction, FTIR spectroscopy, and scanning electron microscopy, along with in vitro tests using simulated body fluid (SBF), phosphate-buffered saline (PBS), and TRIS solution. The results showed that PVP enhanced oxygen vacancy formation and stabilized the scaffolds at 600 °C. Doping with Zn and Mg ions reduced crystallization while significantly increasing the fiber diameters. Scaffolds doped with Zn exhibited lower degradation rates, delayed apatite formation, and hindered ionic release. Conversely, Mg ions facilitated greater interaction with the medium and rapid apatite formation, completely covering the fibers. The scaffolds showed no cytotoxicity in the MTT assay at concentrations of up to 200 µg/mL for HaCat cells and 0.8 mg/mL for L929 cells. This study demonstrated the effectiveness of using PVP in the production of black bioactive glass scaffolds, highlighting their potential for bone regeneration. Full article

The pollution caused by organic dyes in water bodies has become a major environmental issue, and removing such pernicious dyes presents an immense challenge for the scientific community and governments. In this study, a sorbent based on nickel ferrite (NiFe₂O₄) fibers was fabricated by the solution blow spinning (SBS) method for the adsorptive removal of anionic Cong red (CR) dye. The cubic–spinel structure and the magnetic and porous nature of NiFe₂O₄ were confirmed by XRD, magnetometry, BET, and SEM analyses. The saturation magnetization confirmed the magnetic nature of the fibers, which favorably respond to an external magnetic field, facilitating separation from a treated solution. The sorption kinetics of CR on NiFe₂O₄ were best described by the pseudo-second-order model, while sorption equilibrium agreed best with the Freundlich, Langmuir, Sips, and Temkin isotherm models, suggesting a complex mechanism involving chemisorption, monolayer coverage, and heterogeneous adsorption. The NiFe₂O₄ fibers annealed at 500 °C showed a high CR removal efficiency of ~97% after only 30 min. The sorbent’s porous structure and high specific surface area were responsible for the improved removal efficiency. Finally, the results indicated the potential of the NiFe₂O₄ fibers in the remediation of water contaminated with Congo red dye. Full article

Biodegradable polylactic acid (PLA) was used to fabricate nonwoven fabrics via the melt blowing process, followed by electrospinning to deposit a nanofiber membrane. This composite process yielded PLA melt-blown/electrospun composite materials with excellent filtration performance. The effects of the solution concentration and spinning duration on the composite structure and material performance were investigated. The optimal composite was produced using a 10 wt.% PLA spinning solution prepared with a solvent mixture of dichloromethane (DCM) and N, N-dimethylformamide (DMF) in a 75/25 weight ratio. The process parameters included a spinning duration of 5 h, 18 kV voltage, 1.5 mL/h flow rate, and 12 cm collection distance. The resulting composite achieved a filtration efficiency of 98.7%, a pressure drop of 142 Pa, an average pore size of 5 μm, and a contact angle of 138.7°. These results provided optimal process parameters for preparing PLA melt-blown/electrospun composite filtration materials. This study highlights the potential of hydrophobic PLA composites with high filtration efficiency and low air resistance as environmentally friendly alternatives to traditional non-degradable filtration materials. Full article

Polymers play a critical role in the biomedical and sustainable materials fields, serving as key resources for both research and product development. While synthetic and natural polymers are both widely used, synthetic polymers have traditionally dominated due to their ability to meet the specific material requirements of most fiber fabrication methods. However, synthetic polymers are derived from non-renewable resources, and their production raises environmental and health concerns. Natural polymers, on the other hand, are derived from renewable biological sources and include a subset known as biopolymers, such as proteins and polysaccharides, which are produced by living organisms. These biopolymers are naturally abundant and offer benefits such as biodegradability and non-toxicity, making them especially suitable for biomedical and green applications. Recently, air jet spinning has emerged as a promising method for fabricating biopolymer fibers, valued for its simplicity, cost-effectiveness, and safety—advantages that stand out compared to the more conventional electrospinning process. This review examines the methods and mechanisms of air jet spinning, drawing on empirical studies and practical insights to highlight its advantages over traditional fiber production techniques. By assembling natural biopolymers into micro- and nanofibers, this novel fabrication method demonstrates strong potential for targeted applications, including tissue engineering, drug delivery, air filtration, food packaging, and biosensing, utilizing various protein and polysaccharide sources. Full article

This study investigates the impact of micro- and nanocellulose coatings on the properties of wool fabrics using the solution blow spinning technique. The objective is to assess how varying cellulose sizes influence key fabric attributes, including physical properties, UV-shielding ability, air permeability and water vapour permeability, with a focus on their practical applications. Coating with microcrystalline cellulose (MCC) was found to increase the air permeability of fabric significantly, whereas coating with cellulose nanocrystals (CNCs) enhanced water vapour permeability and reduced pore size. The air permeability could relate to the breathability, and water vapour permeability could relate to the comfortability. Coated fabric with both sizes of cellulose could have different applications, like pollen filtration and printable cloth, and further functionality could be achieved by modifying the cellulose structure. This research establishes a platform for the effective application of cellulose coatings on wool fabric, offering promising advancements for textile performance and sustainability. Full article

Solution blow spinning (SBS) is a versatile and cost-effective technique for producing nanofibrous materials. It is based on the principles of other spinning methods as electrospinning (ES), which creates very thin and fine fibers with controlled morphologies. Polylactic acid (PLA), a biodegradable and biocompatible polymer derived from renewable resources, is widely used in biomedical fields, environmental protection, and packaging. This review provides a theoretical background for PLA, focusing on its properties that are associated with structural characteristics, such as crystallinity and thermal behavior. It also discusses various methods for producing fibrous materials, with particular emphasis on ES and SBS and on describing in more detail the main properties of the SBS method, along with its processing conditions and potential applications. Additionally, this review examines the properties of nanofibrous materials, particularly PLA-based nanofibers, and the new applications for which it is thought that they may be more useful, such as drug delivery systems, wound healing, tissue engineering, and food packaging. Ultimately, this review highlights the potential of the SBS method and PLA-based nanofibers in various new applications and suggests future research directions to address existing challenges and further enhance the SBS method and the quality of fibrous materials. Full article

This work presents the successful production of highly porous 3D nanofibrous hybrid scaffolds of polylactic acid (PLA)/polyethylene glycol (PEG) blends with the incorporation of calcium phosphate (CaP) bioceramics by a facile two-step process using the solution blow spinning (SBS) technique. CaP nanofibers were obtained at two calcium/phosphorus (Ca/P) ratios, 1.67 and 1.1, by SBS and calcination at 1000 °C. They were incorporated in PLA/PEG blends by SBS at 10 and 20 wt% to form 3D hybrid cotton-wool-like scaffolds. Morphological analysis showed that the fibrous scaffolds obtained had a randomly interconnected and highly porous structure. Also, the mean fiber diameter ranged from 408 ± 141 nm to 893 ± 496 nm. Apatite deposited considerably within 14 days in a simulated body fluid (SBF) test for hybrid scaffolds containing a mix of hydroxyapatite (HAp) and tri-calcium phosphate-β (β-TCP) phases. The scaffolds with 20 wt% CaP and a Ca/P ration of 1.1 showed better in vitro bioactivity to induce calcium mineralization for bone regeneration. Cellular tests evidenced that the developed scaffolds can support the osteogenic differentiation and proliferation of pre-osteoblastic MC3T3-E1 cells into mature osteoblasts. The results showed that the developed 3D scaffolds have potential applications for bone tissue engineering. Full article

Hybrid nanocomposites combining biopolymer fibers incorporated with nanoparticles (NPs) have received increasing attention due to their remarkable characteristics. Inorganic NPs are typically chosen for their properties, such as magnetism and thermal or electrical conductivity, for example. Meanwhile, the biopolymer fiber component is a backbone, and could act as a support structure for the NPs. This shift towards biopolymers over traditional synthetic polymers is motivated by their sustainability, compatibility with biological systems, non-toxic nature, and natural decomposition. This study employed the solution blow spinning (SBS) method to obtain a nanocomposite comprising poly(vinyl pyrrolidone), PVA, and gelatin biodegradable polymer fibers incorporated with magnetic iron oxide nanoparticles coated with poly(acrylic acid), PAA_2k, coded as γ-Fe₂O₃-NPs-PAA_2k. The fiber production process entailed a preliminary investigation to determine suitable solvents, polymer concentrations, and spinning parameters. γ-Fe₂O₃-NPs were synthesized via chemical co-precipitation as maghemite and coated with PAA_2k through the precipitation–redispersion protocol in order to prepare γ-Fe₂O₃-NPs-PAA_2k. Biopolymeric fibers containing coated NPs with sub-micrometer diameters were obtained, with NP concentrations ranging from 1.0 to 1.7% wt. The synthesized NPs underwent characterization via dynamic light scattering, zeta potential analysis, and infrared spectroscopy, while the biopolymer fibers were characterized through scanning electron microscopy, infrared spectroscopy, and thermogravimetric analysis. Overall, this study demonstrates the successful implementation of SBS for producing biopolymeric fibers incorporating iron oxide NPs, where the amalgamation of materials demonstrated superior thermal behavior to the plain polymers. The thorough characterization of the NPs and fibers provided valuable insights into their properties, paving the way for their potential applications in various fields such as biomedical engineering, environmental remediation, and functional materials. Full article

Nanofibers, with their high surface area-to-volume ratio and unique physical properties, hold significant promise for a wide range of applications, including medical devices, filtration systems, packaging, electronics, and advanced textiles. However, their development and commercialization are hindered by several key challenges and hazards. The main issues are production cost and yield, high voltage, clogging, and toxic materials driven by complex production techniques, which limit their adoption. Additionally, there are environmental and health concerns associated with nanofiber production and disposal, necessitating the development of safer and more sustainable processes and materials. Addressing these challenges requires continued innovation in materials science and industrial practices, as well as a concerted effort to balance production, material, and surrounding condition parameters. This study emphasizes the challenges and hazards associated with nanofiber materials and their production techniques, including electrospinning, centrifugal spinning, solution blow spinning, electro-blown spinning, wet spinning, and melt spinning. It also emphasizes biopolymers and recycling as sustainable and eco-friendly practices to avoid harming the environment and human beings. Full article

In this work, the resistance of polylactide-based non-wovens produced by solution blow spinning to environmental factors was investigated. An average contact angle of up to 136° was achieved with an average fiber diameter of 340 nm at the optimal material density and nozzle–substrate distance. When exposed to ultraviolet (UV) radiation, the polylactide non-wovens rapidly lose their hydrophobic properties due to changes in surface morphology resulting from fiber melting. It was demonstrated that the influence of surface structural features on hydrophobicity is greater than that of the material itself. The stability of the wetting properties under UV irradiation was assessed using the derivative parameters of the Owens–Wendt technique, which can serve as an additional method for estimating surface polarity. Full article

α-Fe₂O₃ and FeMnO₃/α-Fe₂O₃ fibers were successfully prepared via Solution Blow Spinning (SBS). The effect of drying during the SBS process on fiber morphology was evaluated by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and N₂ adsorption–desorption isotherms. A slow drying promoted continuous fibers with rough surfaces and lower average diameters. However, fast drying enabled the production of fibers with low densification and many surface pores with higher BET-specific surface areas. The porous fibers produced have potential applications in energy generation and storage. Full article