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Review

66 Citations

10,588 Views

10 Pages

OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis—Focus on Rocatinlimab and Amlitelimab

Ana Maria Lé and
Tiago Torres

Pharmaceutics2022, 14(12), 2753;https://doi.org/10.3390/pharmaceutics14122753

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8 December 2022

Despite the recent emergence of targeted therapeutic options, there are still unmet needs concerning moderate-to-severe atopic dermatitis treatment. This review aims to discuss the OX40-OX40L pathway as a therapeutic target for the treatment of atopi...

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Review

7 Citations

8,357 Views

13 Pages

Biologic and Small Molecule Therapy in Atopic Dermatitis

Mahek Shergill,
Barinder Bajwa,
Orhan Yilmaz,
Karishma Tailor,
Naila Bouadi and
Ilya Mukovozov

Biomedicines2024, 12(8), 1841;https://doi.org/10.3390/biomedicines12081841

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13 August 2024

Atopic dermatitis is a chronic inflammatory dermatosis characterized by pruritic, scaly, erythematous lesions. Its incidence varies but is estimated to be approximately 20% in children and between 7 and 14% in adults, with variation amongst countries...

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Review

15 Citations

11,157 Views

23 Pages

A Comprehensive Review of Biologics in Phase III and IV Clinical Trials for Atopic Dermatitis

Katarzyna Waligóra-Dziwak,
Aleksandra Dańczak-Pazdrowska and
Dorota Jenerowicz

J. Clin. Med.2024, 13(14), 4001;https://doi.org/10.3390/jcm13144001

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9 July 2024

Atopic dermatitis (AD) is a skin condition characterized by significant challenges and a substantial deterioration in the life quality for affected patients. The therapeutic landscape for AD has witnessed a transformative shift with the emergence of...

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