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Article

13 Citations

11,387 Views

51 Pages

Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes

Mathieu F. M. Cellier

Biology2013, 2(1), 233-283;https://doi.org/10.3390/biology2010233

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25 January 2013

The Natural resistance-associated macrophage protein 1 (Nramp1 or Solute carrier 11 member 1, Slc11a1) transports divalent metals across the membrane of late endosomes and lysosomes in professional phagocytes. Nramp1 represents an ancient eukaryotic...

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Article

13 Citations

5,825 Views

18 Pages

CDC25 Inhibition in Acute Myeloid Leukemia–A Study of Patient Heterogeneity and the Effects of Different Inhibitors

Annette K. Brenner,
Håkon Reikvam,
Kristin Paulsen Rye,
Karen Marie Hagen,
Antonio Lavecchia and
Øystein Bruserud

Molecules2017, 22(3), 446;https://doi.org/10.3390/molecules22030446

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11 March 2017

Cell division cycle 25 (CDC25) protein phosphatases regulate cell cycle progression through the activation of cyclin-dependent kinases (CDKs), but they are also involved in chromatin modulation and transcriptional regulation. CDC25 inhibition is rega...

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Article

1,695 Views

19 Pages

Deciphering Transcriptomic Variations in Hematopoietic Lineages: HSCs, EBs, and MKs

Swati Dahariya,
Anton Enright,
Santosh Kumar and
Ravi Kumar Gutti

Int. J. Mol. Sci.2024, 25(18), 10073;https://doi.org/10.3390/ijms251810073

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19 September 2024

In the realm of hematopoiesis, hematopoietic stem cells (HSCs) serve as pivotal entities responsible for generating various blood cell types, initiating both the myeloid and lymphoid branches within the hematopoietic lineage. This intricate process i...

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