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176 Results Found

  • Article
  • Open Access
1 Citations
2,237 Views
16 Pages

Private Weakly-Random Sequences from Human Heart Rate for Quantum Amplification

  • Maciej Stankiewicz,
  • Karol Horodecki,
  • Omer Sakarya and
  • Danuta Makowiec

8 September 2021

We investigate whether the heart rate can be treated as a semi-random source with the aim of amplification by quantum devices. We use a semi-random source model called ε-Santha–Vazirani source, which can be amplified via quantum protocols to obtain a...

  • Abstract
  • Open Access
1 Citations
1,975 Views
2 Pages

Aptamers are nucleic acid ligands which exhibit specific binding to a desired target. Oligonucleotides are limited in their ability to form hydrophobic interactions. The affinity of aptamers can be improved with the introduction of hydrophobic modifi...

  • Article
  • Open Access
21 Citations
4,294 Views
20 Pages

Deep Impact of Random Amplification and Library Construction Methods on Viral Metagenomics Results

  • Béatrice Regnault,
  • Thomas Bigot,
  • Laurence Ma,
  • Philippe Pérot,
  • Sarah Temmam and
  • Marc Eloit

7 February 2021

Clinical metagenomics is a broad-range agnostic detection method of pathogens, including novel microorganisms. A major limit is the low pathogen load compared to the high background of host nucleic acids. To overcome this issue, several solutions exi...

  • Article
  • Open Access
6 Citations
2,718 Views
37 Pages

Utilizing Artificial Neural Networks and Random Forests to Forecast the Dynamic Amplification Factors of Non-Structural Components

  • P. Vyshnavi,
  • S. P. Challagulla,
  • Musa Adamu,
  • Felipe Vicencio,
  • Mohammed Jameel,
  • Yasser E. Ibrahim and
  • Omar Shabbir Ahmed

16 October 2023

Soft stories in buildings are well-known to present structural vulnerabilities during seismic events, and the failure of non-structural components (NSCs) has been evident in past earthquakes, along with structural damage. This study seeks to investig...

  • Article
  • Open Access
4 Citations
2,829 Views
14 Pages

Privacy amplification is an important step in the post-processing of quantum communication, which plays an indispensable role in the security of quantum key distribution systems. In this paper, we propose a Cellular Automata-based privacy amplificati...

  • Article
  • Open Access
12 Citations
4,539 Views
13 Pages

Privacy amplification is an indispensable procedure for key generation in the quantum key distribution system and the physical layer key distribution system. In this paper, we propose a high-speed privacy amplification algorithm that saves hardware m...

  • Article
  • Open Access
2,370 Views
18 Pages

Method of Moments Optimization of Distributed Raman Amplification in Fibers with Randomly Variying Birefringence

  • Antonio Ortiz-Mora,
  • Pedro Rodríguez,
  • Antonio Díaz-Soriano,
  • David Martínez-Muñoz and
  • Antonio Dengra

In this work, we develop a vectorial model, for optical communications, using distributed Raman amplification (DRA) applied to vectorial soliton pulses in monomode fiber optics. The main result, a dependent polarization effective Raman gain coefficie...

  • Article
  • Open Access
281 Views
29 Pages

7 February 2026

The accurate prediction of extreme dynamic amplification factor (DAF) values is significantly important to ensure a long-term safety assessment of bridges under stochastic vehicular loading. However, predicting extreme DAFs is challenging due to traf...

  • Article
  • Open Access
6 Citations
2,851 Views
16 Pages

27 July 2023

Calcium ions (Ca2+) are abundantly present in the human body; they perform essential roles in various biological functions. In this study, we propose a highly sensitive and selective biosensor platform for Ca2+ detection, which comprises a dual-gate...

  • Article
  • Open Access
1,824 Views
17 Pages

Background/Objectives: Hearing aids can be used as a treatment for tinnitus. There are indications that this treatment is most effective when the tinnitus pitch falls in the frequency range of amplification of the hearing aid. Then, the hearing aid p...

  • Article
  • Open Access
1 Citations
1,901 Views
18 Pages

14 January 2023

Based on Biot’s theory and the indirect boundary element method (IBEM), the Monte Carlo method is utilized to generate random samples to calculate the displacement response of a saturated sedimentary valley under SV wave incidence. The purpose...

  • Article
  • Open Access
14 Citations
3,531 Views
12 Pages

Novel Lineage of Infectious Bronchitis Virus from Sub-Saharan Africa Identified by Random Amplification and Next-Generation Sequencing of Viral Genome

  • Krisztina Bali,
  • Eszter Kaszab,
  • Szilvia Marton,
  • Seydou Hamadou Hamdiou,
  • Reza Karim Bentaleb,
  • István Kiss,
  • Vilmos Palya and
  • Krisztián Bányai

25 March 2022

Avian infectious bronchitis (IB) is among the major viral respiratory and reproductive diseases of chickens caused by Avian coronavirus. In the African continent, IB was first described in countries located in the Mediterranean basin. In other parts...

  • Article
  • Open Access
5,199 Views
13 Pages

Mean-Field Analysis with Random Perturbations to Detect Gliders in Cellular Automata

  • Juan Carlos Seck-Tuoh-Mora,
  • Joselito Medina-Marin,
  • Norberto Hernández-Romero and
  • Genaro J. Martínez

17 October 2023

Cellular automata are mathematical models that represent systems with complex behavior through simple interactions between their individual elements. These models can be used to study unconventional computational systems and complexity. One notable a...

  • Article
  • Open Access
520 Views
12 Pages

27 October 2025

Studying the luminescent properties and the light amplification capabilities are fundamental investigations for newly synthesized organic compounds intended to act as chromophores. These studies are conducted for compounds in the form of solutions, s...

  • Article
  • Open Access
1 Citations
2,142 Views
16 Pages

Nanoscatterer-Assisted Fluorescence Amplification Technique

  • Sylvain Bonnefond,
  • Antoine Reynaud,
  • Julie Cazareth,
  • Sophie Abélanet,
  • Massimo Vassalli,
  • Frédéric Brau and
  • Gian Luca Lippi

30 October 2023

Weak fluorescence signals, which are important in research and applications, are often masked by the background. Different amplification techniques are actively investigated. Here, a broadband, geometry-independent and flexible feedback scheme based...

  • Article
  • Open Access
1,797 Views
14 Pages

Viral Diversity in Benthic Abyssal Ecosystems: Ecological and Methodological Considerations

  • Umberto Rosani,
  • Cinzia Corinaldesi,
  • Gabriella Luongo,
  • Marco Sollitto,
  • Simeone Dal Monego,
  • Danilo Licastro,
  • Lucia Bongiorni,
  • Paola Venier,
  • Alberto Pallavicini and
  • Antonio Dell’Anno

21 November 2023

Viruses are the most abundant ‘biological entities’ in the world’s oceans. However, technical and methodological constraints limit our understanding of their diversity, particularly in benthic abyssal ecosystems (>4000 m depth)....

  • Article
  • Open Access
9 Citations
2,034 Views
19 Pages

The dynamic response characteristics of a two-dimensional submerged floating tunnel (SFT) under random and freak waves were investigated in the present study. The results demonstrate that (1) the dynamic responses of the SFT under the freak wave are...

  • Article
  • Open Access
4 Citations
1,995 Views
21 Pages

The values of the physical–mechanical properties of any soil are affected by uncertainties both due to experimental measurements and the impossibility of knowing them, in detail, at every point of the spatial domain. Accordingly, this work focu...

  • Proceeding Paper
  • Open Access
1,637 Views
5 Pages

In this study, a rubber vibration isolator is designed for certain aerospace equipment, and a finite element simulation is carried out to obtain the modal frequency and random vibration response, and to verify the accuracy of the design. The test ver...

  • Article
  • Open Access
5 Citations
1,963 Views
12 Pages

2 November 2022

In this paper, we study the asymptotic and transient dynamics of a predator–prey model with square root functional responses and random perturbation. Firstly, the mean square stability matrix is obtained from the stability theory of stochastic...

  • Article
  • Open Access
7 Citations
3,294 Views
9 Pages

Isolation and Antimicrobial Sensitivity of Mycoplasma synoviae and Mycoplasma gallisepticum from Vaccinated Hens in Mexico

  • Víctor M. Petrone-Garcia,
  • Guillermo Tellez-Isaias,
  • Fernando Alba-Hurtado,
  • Christine N. Vuong and
  • Raquel Lopez-Arellano

7 November 2020

Mycoplasma synoviae (MS) and Mycoplasma gallisepticum (MG) strains were isolated at 39.5 °C to rule out temperature-sensitive strains (ts+) and identified using random amplification of polymorphic DNA. Then, their minimum inhibitory concentration...

  • Article
  • Open Access
2,143 Views
9 Pages

An Organic Microcavity Laser Amplifier Integrated on the End Facet of an Optical Fiber

  • Meng Wang,
  • Zhuangzhuang Xu,
  • Yaqi Ren,
  • Xiaolei Bai and
  • Xinping Zhang

4 August 2024

We report a thin-film optical amplifier integrated on a fiber facet based on polymer-coated distributed feedback (DFB) microcavities, which are fabricated on a planar substrate and then transferred onto fiber tips by means of a flexible transfer tech...

  • Article
  • Open Access
5 Citations
4,423 Views
17 Pages

A Novel Synthetic Antibody Library with Complementarity-Determining Region Diversities Designed for an Improved Amplification Profile

  • Xuelian Bai,
  • Moonseon Jang,
  • Nam Ju Lee,
  • Thi Thu Ha Nguyen,
  • Mooyoung Jung,
  • Jeong Yeon Hwang and
  • Hyunbo Shim

Antibody discovery by phage display consists of two phases, i.e., the binding phase and the amplification phase. Ideally, the selection process is dominated by the former, and all the retrieved clones are amplified equally during the latter. In reali...

  • Article
  • Open Access
4 Citations
2,538 Views
15 Pages

Key Action Mechanisms of Intentional Mistuning

  • Jose Joaquin Sánchez-Álvarez and
  • Carlos Martel

18 June 2021

Intentional mistuning is a common procedure to decrease the uncontrolled vibration amplification effects of the (unavoidable) random mistuning, and to reduce the sensitivity to it. The idea is to introduce an intentional mistuning pattern that is sma...

  • Article
  • Open Access
20 Citations
6,708 Views
24 Pages

Platinum-Quality Mitogenome Haplotypes from United States Populations

  • Cassandra R. Taylor,
  • Kevin M. Kiesler,
  • Kimberly Sturk-Andreaggi,
  • Joseph D. Ring,
  • Walther Parson,
  • Moses Schanfield,
  • Peter M. Vallone and
  • Charla Marshall

29 October 2020

A total of 1327 platinum-quality mitochondrial DNA haplotypes from United States (U.S.) populations were generated using a robust, semi-automated next-generation sequencing (NGS) workflow with rigorous quality control (QC). The laboratory workflow in...

  • Article
  • Open Access
22 Citations
5,817 Views
15 Pages

4 December 2015

Orography strongly interacts with the atmospheric circulation, especially during frontal events, generating an enhanced spatial variability of the rainfall field. Regional models of extreme rainfall have to deal with these circumstances in order to p...

  • Article
  • Open Access
27 Citations
5,850 Views
13 Pages

Enhancing Extractable Quantum Entropy in Vacuum-Based Quantum Random Number Generator

  • Xiaomin Guo,
  • Ripeng Liu,
  • Pu Li,
  • Chen Cheng,
  • Mingchuan Wu and
  • Yanqiang Guo

24 October 2018

Information-theoretically provable unique true random numbers, which cannot be correlated or controlled by an attacker, can be generated based on quantum measurement of vacuum state and universal-hashing randomness extraction. Quantum entropy in the...

  • Article
  • Open Access
1 Citations
1,974 Views
10 Pages

A Theoretical and Experimental Analysis of the Time-Domain Characteristics of a PRBS Phase-Modulated Laser System

  • Yun Zhu,
  • Ying Li,
  • Dong Li,
  • Lin Dong,
  • Xuesheng Liu,
  • Anru Yan,
  • Youqiang Liu and
  • Zhiyong Wang

10 October 2024

Pseudo-Random Binary Sequence (PRBS) phase modulation is an effective method for suppressing the stimulated Brillouin scattering (SBS) effect generated by narrow-linewidth fiber lasers during amplification. We noticed that backward time-domain pulses...

  • Article
  • Open Access
1,540 Views
23 Pages

28 July 2025

On 22 May 2012, a magnitude Mw 5.6 earthquake struck the Pernik region of western Bulgaria, causing structural damage in nearby cities, including Sofia. This study assesses the seismic response of a six-story reinforced concrete building in central S...

  • Feature Paper
  • Article
  • Open Access
12 Citations
4,021 Views
33 Pages

Gaussian Amplitude Amplification for Quantum Pathfinding

  • Daniel Koch,
  • Massimiliano Cutugno,
  • Samuel Karlson,
  • Saahil Patel,
  • Laura Wessing and
  • Paul M. Alsing

11 July 2022

We study an oracle operation, along with its circuit design, which combined with the Grover diffusion operator boosts the probability of finding the minimum or maximum solutions on a weighted directed graph. We focus on the geometry of sequentially c...

  • Article
  • Open Access
13 Citations
3,438 Views
13 Pages

28 October 2022

According to pigeon racing rules in Taiwan, the pigeon raiser must decide which juveniles will be chosen as soon as possible. Differentiating the sex of young pigeons based on appearances, and other traditional methods, can be time-consuming and requ...

  • Article
  • Open Access
25 Citations
11,475 Views
9 Pages

22 June 2011

Genetic analysis of plants relies on high yields of pure DNA. For the strawberry tree (Arbutus unedo) this represents a great challenge since leaves can accumulate large amounts of polysaccharides, polyphenols and secondary metabolites, which co-puri...

  • Review
  • Open Access
274 Citations
52,301 Views
25 Pages

26 April 2013

From 2006 to 2011, an average of 15 novel recombinant protein therapeutics have been approved by US Food and Drug Administration (FDA) annually. In addition, the expiration of blockbuster biologics has also spurred the emergence of biosimilars. The i...

  • Article
  • Open Access
5 Citations
3,941 Views
13 Pages

Incoherent Shock and Collapse Singularities in Non-Instantaneous Nonlinear Media

  • Gang Xu,
  • Adrien Fusaro,
  • Josselin Garnier and
  • Antonio Picozzi

10 December 2018

We study the dynamics of a partially incoherent optical pulse that propagates in a slowly responding nonlinear Kerr medium. We show that irrespective of the sign of the dispersion (either normal or anomalous), the incoherent pulse as a whole exhibits...

  • Article
  • Open Access
2 Citations
2,103 Views
25 Pages

6 June 2024

The manuscript presents a novel non-gradient and non-iterative method for mapping two 3D objects by matching extrema. This innovative approach utilizes the amplification of extrema through the summation of dependent random values, accompanied by a co...

  • Article
  • Open Access
5 Citations
6,096 Views
13 Pages

11 August 2019

QuickStep is a cloning method that allows seamless point integration of a DNA sequence at any position within a target plasmid using only Q5 High-Fidelity DNA Polymerase and DpnI endonuclease. This efficient and cost-effective method consists of two...

  • Review
  • Open Access
9 Citations
4,475 Views
15 Pages

10 February 2023

Anti-HER2 therapies have dramatically improved the prognosis of human epidermal growth factor receptor 2 (HER2)-overexpressing cancers. However, the correlation between the HER2 copy number and the response rate to anti-HER2 remains unclear. Here, fo...

  • Article
  • Open Access
9 Citations
2,387 Views
23 Pages

14 March 2023

In this paper, we propose a novel Maxwell dynamic vibration absorber (DVA) with lever, inerter, and grounded stiffness. Firstly, the governing equation of the coupled system is established. The analytical formula of the amplitude amplification factor...

  • Article
  • Open Access
4 Citations
3,501 Views
10 Pages

Multimode Graded Index Fiber with Random Array of Bragg Gratings and Its Raman Lasing Properties

  • Alexey G. Kuznetsov,
  • Alexey A. Wolf,
  • Zhibzema E. Munkueva,
  • Alexander V. Dostovalov and
  • Sergey A. Babin

24 May 2023

Light propagation in multimode fibers is known to experience various nonlinear effects, which are being actively studied. One of the interesting effects is the brightness enhancement at the Raman conversion of the multimode beam in graded index (GRIN...

  • Article
  • Open Access
7 Citations
4,586 Views
12 Pages

A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System

  • Seohee Chang,
  • Soohyun Kim,
  • Jerome Han,
  • Suji Ha,
  • Hyunho Lee,
  • Seo Woo Song,
  • Daewon Lee,
  • Sunghoon Kwon,
  • Junho Chung and
  • Junhoi Kim

29 March 2020

Phage display is one of the most frequently used platform technologies utilized to screen and select therapeutic antibodies, and has contributed to the development of more than 10 therapeutic antibodies used in the clinic. Despite advantages like eff...

  • Feature Paper
  • Review
  • Open Access
38 Citations
4,880 Views
16 Pages

SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma

  • Martin Mynarek,
  • Till Milde,
  • Laetitia Padovani,
  • Geert O. Janssens,
  • Robert Kwiecien,
  • Veronique Mosseri,
  • Steven C. Clifford,
  • François Doz and
  • Stefan Rutkowski

2 December 2021

Background. SIOP PNET5 MB was initiated in 2014 as the first European trial using clinical, histological, and molecular parameters to stratify treatments for children and adolescents with standard-risk medulloblastoma. Methods. Stratification by upfr...

  • Article
  • Open Access
1,347 Views
27 Pages

6 August 2025

Modern cloud-based Internet of Things (IoT) infrastructures face increasingly sophisticated and diverse cyber threats that challenge traditional detection systems in terms of scalability, adaptability, and explainability. In this paper, we present (H...

  • Article
  • Open Access
4 Citations
2,010 Views
12 Pages

24 June 2024

The sensitivity of immunoassays is generally limited by the low signal reporter/recognition element ratio. Nanomaterials serving as the carriers can enhance the loading number of signal reporters, thus improving the detection sensitivity. However, th...

  • Article
  • Open Access
8 Citations
3,112 Views
18 Pages

27 January 2022

The compositive passive control (CPC) method of “interlayer seismic isolation “plus “shock absorption between adjacent towers” was applied to a multi-tower building (MTB) with a large podium. The interaction between adjacent t...

  • Review
  • Open Access
7 Citations
4,562 Views
15 Pages

Treatment Options in Late-Line Colorectal Cancer: Lessons Learned from Recent Randomized Studies

  • Line Schmidt Tarpgaard,
  • Stine Brændegaard Winther and
  • Per Pfeiffer

26 December 2023

Systemic treatment of metastatic colorectal cancer (mCRC) has improved considerably over the past 20 years. First- and second-line combinations of 5FU, oxaliplatin, and irinotecan, with or without anti-angiogenic and/or anti-EGFR antibodies, were app...

  • Article
  • Open Access
5 Citations
2,439 Views
13 Pages

Experimental Study of the Impact of Temperature on Atmospheric Neutron-Induced Single Event Upsets in 28 nm Embedded SRAM of SiP

  • Shunshun Zheng,
  • Zhangang Zhang,
  • Jiefeng Ye,
  • Xiaojie Lu,
  • Zhifeng Lei,
  • Zhili Liu,
  • Gaoying Geng,
  • Qi Zhang,
  • Hong Zhang and
  • Hui Li

In this paper, the temperature dependence of single event upset (SEU) cross-section in 28 nm embedded Static Random Access Memory (SRAM) of System in Package (SiP) was investigated. An atmospheric neutron beam with an energy range of MeV~GeV was util...

  • Article
  • Open Access
9 Citations
9,916 Views
11 Pages

In an effort towards adapting new and defensible methods for assessing and managing the risk posed by microbial pollution, we evaluated the utility of oligonucleotide microarrays for bacterial source tracking (BST) of environmental Enterococcus sp. i...

  • Communication
  • Open Access
5 Citations
2,712 Views
10 Pages

Direct Measurement of the Reduced Scattering Coefficient by a Calibrated Random Laser Sensor

  • Federico Tommasi,
  • Baptiste Auvity,
  • Lorenzo Fini,
  • Fabrizio Martelli and
  • Stefano Cavalieri

11 February 2022

The research in optical sensors has been largely encouraged by the demand for low-cost and less or non-invasive new detection strategies. The invention of the random laser has opened a new frontier in optics, providing also the opportunity to explore...

  • Article
  • Open Access
1,463 Views
42 Pages

Black-Box Bug Amplification for Multithreaded Software

  • Yeshayahu Weiss,
  • Gal Amram,
  • Achiya Elyasaf,
  • Eitan Farchi,
  • Oded Margalit and
  • Gera Weiss

9 September 2025

Bugs, especially those in concurrent systems, are often hard to reproduce because they manifest only under rare conditions. Testers frequently encounter failures that occur only under specific inputs, often at low probability. We propose an approach...

  • Article
  • Open Access
1 Citations
1,451 Views
32 Pages

22 July 2025

In device-independent (DI) quantum protocols, security statements are agnostic to the internal workings of the quantum devices—they rely solely on classical interactions with the devices and specific assumptions. Traditionally, such protocols a...

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