Search Results (155)

This review focuses on five native Australian brown algae species—Cystophora torulosa, Durvillaea potatorum, Ecklonia radiata, Hormosira banksii, and Phyllospora comosa—evaluating their environmental adaptability, biochemical composition, bioactive compounds, and potential for commercial development. Species-specific differences in temperature and light tolerance influence their habitat distribution. Nutritional assessments reveal that these algae are rich in proteins, polysaccharides, polyunsaturated fatty acids, and essential trace elements. Bioactive compounds, including polyphenols and fucoidans, exhibit antioxidant, anti-inflammatory, and anti-diabetic properties. D. potatorum extracts have considerable economic value in agriculture by enhancing crop yield, improving nutritional value, and promoting root development. C. torulosa is predominantly found in cooler marine environments and is comparatively more thermally sensitive. In contrast, H. banksii has a higher heat tolerance of up to 40 °C and thrives in warmer environments. E. radiata is widely distributed, highly tolerant of environmental stresses, and exhibits notable disease-resistant activities. P. comosa, due to its high polysaccharide content, demonstrates strong potential for industrial applications. Consumer studies indicate growing acceptance of seaweed-based products in Australia, although knowledge gaps remain. This study highlights the need for continued research, optimized processing methods, and targeted education to support the sustainable development and utilization of Australia’s native brown algae resources. Full article

Edible coatings and films are gaining the attention of researchers, consumers, and the food industry as a sustainable alternative to conventional plastic packaging. This review provides an overview of recent advances in their development, with a particular focus on new natural sources of biomaterials (e.g., proteins and polysaccharides) and natural additives (antioxidants and antimicrobials). Special attention is given to high-technology preparation methods, including electrohydrodynamic atomization (EHDA), as well as controlled release systems for bioactive compounds designed to preserve foodstuffs and extended their shelf life. The application of edible coatings as carriers of nutrients (vitamins) and bioactives (probiotics and polyphenols) to improve the nutritional value and support the development of functional foods is also discussed. In addition, this review addresses safety considerations and regulatory aspects that are crucial for commercialization and consumer acceptance. Finally, key challenges are highlighted, including the improvement of mechanical and barrier properties, scalability of innovative technologies, consumer education, regulatory support, and the integration of circular economy principles, to encourage the adoption of these sustainable solutions. Full article

Apple by-products are a valuable raw material due to their high content of dietary fiber, minerals, and bioactive compounds, making them a promising functional ingredient in food products. The aim of this study was to evaluate the effect of adding a residue obtained from the isolation of starch from unripe apples of the Pyros and Oliwka varieties on the nutritional composition, mineral content, polyphenol and fiber levels, and color of wheat muffins. Additionally, the oxidative stability was analyzed. The results showed that the addition of the residue significantly increased the total, soluble, and insoluble fiber content, as well as the protein content. The polysaccharide fraction residue from unripe Oliwka apples had a stronger impact on enhancing the fiber content of the muffins. In contrast, muffins enriched with the polysaccharide fraction residue from unripe Pyros apples exhibited higher levels of calcium, potassium, and magnesium, while the Oliwka residue increased the contents of sodium, strontium, and iron. The addition of the polysaccharide fraction residue significantly increased the levels of chlorogenic acid, phloridzin, quercetin, and procyanidin B1. Color analysis revealed a darkening effect in the muffins after the addition of the residue, and the oxidative stability decreased with increasing levels of the polysaccharide fraction residue. This study demonstrated that apple residues obtained after starch isolation can effectively enrich muffins with nutrients and health-promoting compounds; however, their impact on oxidative stability requires further investigation. Full article

Selenium (Se) is an essential trace element for the human body and plays a vital role in various physiological processes. Plants serve not only as a major dietary source of selenium but also as natural biofactories capable of synthesizing a wide range of organic selenium compounds. The bioavailability and toxicity of selenium are highly dependent on its chemical form, which can exert varying effects on human physiology. Among these, organic selenium species exhibit higher bioavailability, lower toxicity, and greater structural diversity. In recent years, plant-derived selenium-containing compounds—selenium-enriched proteins, peptides, polysaccharides, polyphenols, and nanoselenium—have garnered increasing scientific attention. Through a systematic search of databases including PubMed, Web of Science, and Scopus, this review provides a comprehensive overview of selenium uptake and transformation in plants, selenium metabolism in humans, and the classification, composition, structural features, and biological activities of plant-derived selenium compounds, thereby providing a theoretical basis for future research on functional foods and nutritional interventions. Full article

The white button mushroom (Agaricus bisporus) is a widely cultivated edible and medicinal mushroom, which contains various active substances, and has application value against pathogenic bacteria in aquaculture. Firstly, A. bisporus water extract (AB-WE) was prepared. Through the detection kits, it was found that the polysaccharide, protein, and polyphenol components of AB-WE were 9.11%, 3.3%, and 1.5%, respectively. The 246 compounds were identified in AB-WE, and the major small-molecule components included L-Isoleucine, L-Tyrosine, L-Valine, and Linoleic acid by HPLC-Q Exactive-Orbitrap-MS. Secondly, the AB-WE was evaluated for its immunological activities through dietary administration and pathogen challenge (Aeromonas hydrophila and Vibrio fluvialis) in goldfish (Carassius auratus). The results showed that the levels of immune factors of acid phosphatase (ACP), alkaline phosphatase (AKP), and lysozyme (LZM) increased (p < 0.05) in goldfish, and the relative percentage survival of AB-WE against A. hydrophila and V. fluvialis were 80.00% (p < 0.05) and 81.82% (p < 0.05), respectively. The AB-WE reduced the bacterial content in renal tissue, enhanced the phagocytic activity of leukocytes, and exhibited antioxidant and anti-inflammatory effects by reducing the expression of antioxidant-related factors and inflammatory factors. Through histopathological and immunofluorescence techniques, it was found that AB-WE maintained the integrity of visceral tissues and reduced renal tissue apoptosis and DNA damage. Therefore, AB-WE exhibits immunoprotective activity against A. hydrophila and V. fluvialis infections in fish, and holds promise as an immunotherapeutic agent against major pathogenic bacteria in aquaculture. Full article

Background: During food processing and storage, traditional protein-based delivery systems encounter significant challenges in maintaining the structural and functional integrity of bioactive compounds, primarily due to their temporal instability. Methods: In this study, a nanocomposite hydrogel was prepared through the co-assembly of a self-assembling peptide, 9-Fluorenylmethoxycarbonyl-phenylalanine-arginine-glycine-aspartic acid-phenylalanine (Fmoc-FRGDF), and hyaluronic acid (HA). The stability of this hydrogel as a quercetin (Que) delivery carrier was systematically investigated. Furthermore, the impact of Que co-assembly on the microstructural evolution and physicochemical properties of the hydrogel was characterized. Concurrently, the encapsulation efficiency (EE%) and controlled release kinetics of Que were quantitatively evaluated. Results: The findings indicated that HA significantly reduced the storage modulus (G′) from 256.5 Pa for Fmoc-FRGDF to 21.1 Pa with the addition of 0.1 mg/mL HA. Despite this reduction, HA effectively slowed degradation rates; specifically, residue rates of 5.5% were observed for Fmoc-FRGDF alone compared to 14.1% with 0.5 mg/mL HA present. Notably, Que enhanced G′ within the ternary complex, increasing it from 256.5 Pa in Fmoc-FRGDF to an impressive 7527.0 Pa in the Que/HA/Fmoc-FRGDF hydrogel containing 0.1 mg/mL HA. The interactions among Que, HA, and Fmoc-FRGDF involved hydrogen bonding, electrostatic forces, and hydrophobic interactions; furthermore, the co-assembly process strengthened the β-sheet structure while significantly promoting supramolecular ordering. Interestingly, the release profile of Que adhered to the Korsmeyer–Peppas pharmacokinetic equations. Conclusions: Overall, this study examines the impact of polyphenol on the rheological properties, microstructural features, secondary structure conformation, and supramolecular ordering within peptide–polysaccharide–polyphenol ternary complexes, and the Fmoc-FRGDF/HA hydrogel system demonstrates a superior performance as a delivery vehicle for maintaining quercetin’s bioactivity, thereby establishing a multifunctional platform for bioactive agent encapsulation and controlled release. Full article

Background/Objectives: In recent years, increasing attention has been paid to the stabilization of natural biologically active compounds in order to expand their application in the food, pharmaceutical, and cosmetic industries. Such compounds, such as polyphenols, essential fatty acids, or vitamins, are extremely sensitive to environmental factors. This study aims to review the spray-drying-based microencapsulation technology and its application for stabilizing sensitive biologically active substances. Methods: This article systematically analyzes the main steps of the spray-drying microencapsulation process and discusses traditional and innovative wall materials, including natural polymers (polysaccharides and proteins), as well as new raw material sources (e.g., yeast cells, canola and pea protein isolates, and hemicelluloses). It also examines the potential of these systems for the stimulated release of active ingredients. Results: This review provides a comprehensive overview of the main stages of the spray-drying process and critically examines both conventional (e.g., maltodextrin and gum Arabic) and innovative wall materials (e.g., plant-based proteins and food industry by-products). Studies show that using different wall materials can achieve high encapsulation efficiency, improve the stability of biologically active substances, and control their release. Various compounds have been successfully microencapsulated—polyphenols, essential oils, carotenoids, fatty acids, and vitamins—protecting them from oxidation, light, and temperature. The review identifies key factors that can enhance product quality, increase encapsulation yield, and reduce processing costs and energy input—offering meaningful insights for optimizing the microencapsulation process. Conclusions: Spray-drying-based microencapsulation is an advanced technology that effectively protects sensitive active ingredients and allows for wider industrial food, pharmaceutical, and cosmetic applications. In the future, more attention is expected to be paid to personalized formulations, stimulated release systems, and sustainable wall materials from by-products. Full article

Wild fruits are distributed worldwide, but are consumed mainly in developing countries, where they are an important part of the diet. Still, in many other countries, they are consumed only locally. Blackthorn (Prunus spinosa L.) is an underutilized species rich in fibres and phenolic compounds, making it suitable as a potential functional food for supporting human health. Cold (Cw) and hot (Hw) water-extracted (poly)phenolic polysaccharide–protein complexes, differing in carbohydrate, phenolic and protein contents, were isolated from blackthorn fruits and characterized. The complexes exhibited molecular weights of 235,200 g/mol (Cw) and 218,400 g/mol (Hw), and were rich in pectic polymers containing galacturonic acid, arabinose, galactose and rhamnose, indicating a dominance of homogalacturonan (HG) [→4)-α-D-GalA(1→4)-α-D-GalA(1→]n and a low content of RGI [→2)-α-L-Rha(1→4)-α-D-GalA(1→2)-α-L-Rha(1→]n sequences associated with arabinan or arabinogalactan. Minor content of glucan, probably starch-derived, was also solubilized. Pectic polysaccharides were highly esterified and partly acetylated. Pharmacological testing was performed in male Dunkin–Hartley guinea pigs, a model with human-like airway reflexes. Both complexes affected airway defense mechanisms. Particularly, Hw significantly suppressed citric acid-induced cough, similar to codeine, and reduced bronchoconstriction comparably to salbutamol in a dose-dependent manner. These findings support further exploration of Hw as a natural antitussive and bronchodilatory agent. Full article

Growing consumer awareness of clean labels is driving demand for preservative-free products yet concerns about foodborne pathogens and microbiological safety remain significant. Plant-derived compounds with bioactive properties—phytobiotics—have emerged as promising alternatives or complements to conventional antimicrobial agents. This review discusses phytobiotics, including essential oils, polyphenols, alkaloids, and organosulfur compounds, highlighting their structural diversity and antimicrobial potential. Phytobiotics combat foodborne pathogens by disrupting cell structures, inhibiting biofilms and quorum sensing, and interfering with genetic and protein synthesis. Importantly, some phytobiotics exhibit synergistic effects when combined with antibiotics or other natural agents, enhancing overall antimicrobial efficacy. The impact of phytobiotics on the microbiota of food products and the gastrointestinal tract is also addressed, with attention to both beneficial modulation and possible unintended effects. Practical applications in food preservation and supplementation are analyzed, as well as challenges related to composition variability, stability, and interactions with food matrices. Nevertheless, modern technologies such as nanoencapsulation, complexation with polysaccharides, and advanced extraction methods are being developed to address these challenges and enhance the stability and bioavailability of phytobiotics. Continued investment in research and innovation is essential to fully harness the potential of phytobiotics in ensuring safe, natural, and sustainable food systems. Full article

In recent years, there has been a growing interest in identifying both the macro- and micro-constituents of milk, as their functional and health benefits have been recognized. This review provides a comprehensive overview of all milk constituents, including fats, proteins, oligosaccharides and polysaccharides, vitamins, minerals and polyphenols, along with their extraction protocols and the analytical methods employed for their separation and detection over the last ten years. The principles, strengths and limitations of these methods are discussed, highlighting their importance in advancing milk research. Traditional methods such as spectrophotometry, and advanced technologies, like mass spectrometry and omics approaches, are described to collectively enable a comprehensive understanding of milk’s nutritional and functional components. Election criteria for the analytical platforms suitable for target analytes are provided. Full article

Currently, marine algae are still an under-exploited natural bioresource of bioactive compounds. Seaweeds represent a sustainable source for obtaining bioactive compounds that can be useful for the fabrication of new active products with biomedical benefits and applications as biomedicinals and nutraceuticals. The objective of this review is to highlight scientific papers that identify biocompounds from marine macroalgae and emphasize their benefits. The method used was data analysis to systematize information to identify biocompounds and their various benefits in pharmaceuticals, cosmetics, and nutraceuticals. The research results demonstrate the multiple uses of seaweeds. As pharmaceuticals, seaweeds are rich sources of bioactive compounds like polysaccharides, protein compounds, pigments, and polyphenols, which have demonstrated various pharmacological activities such as antioxidant, antibacterial, anti-inflammatory, antiviral, anticoagulant, and potentially anticarcinogenic effects. Seaweed has gained recognition as a functional food and offers a unique set of compounds that promote body health, including vitamins, minerals, and antioxidants. In conclusion, the importance of this review is to expand the possibilities for utilizing natural resources by broadening the areas of research for human health and marine nutraceuticals. Full article

Background: Edible insects, such as Tenebrio molitor larvae (TM), offer a sustainable protein alternative to meet increasing dietary demands. The aim of this study is to investigate the functionalization of durum wheat pasta through the incorporation of TM flour (0–30%), focusing on how the addition of this non-conventional ingredient affects pasta production processing and its technological and chemical characteristics. Methods: Pasting properties, color, total phenolic content, antioxidant activity, and reducing sugars were determined for dry and cooked pasta. Texture profile and cooking properties were assessed for cooked samples. Results: The insect flour contributed to enhance polyphenols content in pasta, which increased from 0.06 and 0.03 mg_GAE/g up to 0.19 and 0.10 mg_GAE/g for dry and cooked pasta, respectively, and remained constant after the production process. The addition of TM flour altered the microstructure of wheat macromolecules, forming complex molecules, such as amylose–lipid complexes, and hydrogen and electrostatic interactions between proteins and polysaccharides, contributing to improved molecular stability and bioactivity. The pasta produced with insect flour up to 10% showed water absorption capacity, cooking properties, and consistency comparable to those of traditional pasta. Moreover, the addition of TM flour led to a reduction in peak viscosities from 2146.5 cP to 911.5 cP and roughness of pasta. Conclusions: The findings demonstrated the potential of TM flour as a unique source of bioactive compounds enhancing both the nutritional and functional properties of durum wheat pasta. Overcoming processing challenges through the optimization of product formulation and process parameters is crucial for exploring the production of insect flour enriched pasta at industrial scale while maintaining product uniformity and satisfying consumers expectations. Full article

The therapeutic potential of natural products has led to the exploitation of phytocomplexes for treating various skin conditions, including wounds. Echinacea angustifolia DC. has traditionally been used for wound healing, burns, and other ailments. In this study, dried roots of E. angustifolia were extracted using a hydroalcoholic solution, and the phytochemical composition was analyzed through HPLC-DAD. The polyphenol and polysaccharide content, along with in vitro antioxidant and anti-tyrosinase properties, were evaluated. The biological effect of E. angustifolia extract was evaluated on the 3T3-L1 cell line. HPLC-DAD analysis confirmed the presence of several polyphenols, particularly caffeic acid derivatives, with echinacoside as the predominant compound, exhibiting strong antioxidant properties. The extract demonstrated no cytotoxic effect on 3T3-L1 cells, and it showed a protective effect by increasing the migration process in an in vitro scratch wound healing test, together with echinacoside and allantoin, which were used as references. Furthermore, the extract reduced the expression of proinflammatory cytokines and promoted that of proteins that accelerate wound closure, such as TGF-β1. The present study demonstrates the potential wound healing properties and the antioxidant and anti-inflammatory activity of E. angustifolia root hydroalcoholic extract, giving a scientific rationale for its traditional use. Full article

Microalgae have emerged as a valuable source of essential nutrients and bioactive compounds, such as proteins, polyphenols, and polysaccharides, which are critical for overall health. Recent research has demonstrated the therapeutic potential of microalgae in addressing a variety of health conditions, including inflammation, oxidative stress, Type 2 diabetes mellitus (T2DM), and neurological disorders. The aim of this paper is to investigate the chemical composition, nutritional value, and biological properties of microalgae. Relevant information was gathered through a comprehensive search of scientific databases, including PubMed, Science Direct, Google Scholar, and the Cochrane Library. Key microalgal strains such as Spirulina platensis, Chlorella vulgaris, Haematococcus pluvialis, and Dunaliella salina have shown notable health-promoting properties. For instance, Spirulina platensis is rich in proteins, vitamins, and polyunsaturated fatty acids, while Chlorella vulgaris offers significant levels of chlorophyll and carotenoids. Haematococcus pluvialis is recognized for its high astaxanthin content and Dunaliella salina for its beta-carotene content. These microalgae strains have demonstrated beneficial effects in managing type 2 diabetes mellitus, alleviating oxidative stress, and offering neuroprotective potential. This paper provides an overview of microalgae’s nutritional composition, their medicinal properties, and their promising role in treating chronic diseases, with a particular focus on their applications in antidiabetic and neuroprotective therapies. Full article