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4 Results Found

  • Article
  • Open Access
21 Citations
8,193 Views
10 Pages

Development of Poly(ɛ-caprolactone) Scaffold Loaded with Simvastatin and Beta-Cyclodextrin Modified Hydroxyapatite Inclusion Complex for Bone Tissue Engineering

  • Jung Bok Lee,
  • Ji Eun Kim,
  • Min Soo Bae,
  • Su A Park,
  • Daniel A. Balikov,
  • Hak-joon Sung,
  • Hoon Bong Jeon,
  • Hun Kuk Park,
  • Soong Ho Um and
  • Kook Sun Lee
  • + 1 author

9 February 2016

In this study, we developed poly(ɛ-caprolactone) (PCL) 3D scaffolds using a solid free form fabrication (SFF) technique. β-cyclodextrin (βCD) was grafted to hydroxyapatite (HAp) and this βCD grafted HAp was coated onto the PCL scaffold surface, follo...

  • Article
  • Open Access
18 Citations
4,293 Views
22 Pages

Poly-ε-Caprolactone/Fibrin-Alginate Scaffold: A New Pro-Angiogenic Composite Biomaterial for the Treatment of Bone Defects

  • Jiongyu Ren,
  • Nupur Kohli,
  • Vaibhav Sharma,
  • Taleen Shakouri,
  • Zalike Keskin-Erdogan,
  • Siamak Saifzadeh,
  • Gary I. Brierly,
  • Jonathan C. Knowles,
  • Maria A. Woodruff and
  • Elena García-Gareta

2 October 2021

We hypothesized that a composite of 3D porous melt-electrowritten poly-ɛ-caprolactone (PCL) coated throughout with a porous and slowly biodegradable fibrin/alginate (FA) matrix would accelerate bone repair due to its angiogenic potential. Scanning el...

  • Article
  • Open Access
34 Citations
10,035 Views
14 Pages

Thermoplastic PCL-b-PEG-b-PCL and HDI Polyurethanes for Extrusion-Based 3D-Printing of Tough Hydrogels

  • Aysun Güney,
  • Christina Gardiner,
  • Andrew McCormack,
  • Jos Malda and
  • Dirk W. Grijpma

Novel tough hydrogel materials are required for 3D-printing applications. Here, a series of thermoplastic polyurethanes (TPUs) based on poly(ɛ-caprolactone)-b-poly(ethylene glycol)-b-poly(ɛ-caprolactone) (PCL-b-PEG-b-PCL) triblock copolymers and hexa...

  • Article
  • Open Access
8 Citations
1,890 Views
19 Pages

Tuning of Silver Content on the Antibacterial and Biological Properties of Poly(ɛ-caprolactone)/Biphasic Calcium Phosphate 3D-Scaffolds for Bone Tissue Engineering

  • Francesca Menotti,
  • Sara Scutera,
  • Bartolomeo Coppola,
  • Fabio Longo,
  • Narcisa Mandras,
  • Lorenza Cavallo,
  • Sara Comini,
  • Rosaria Sparti,
  • Elisa Fiume and
  • Anna Maria Cuffini
  • + 3 authors

31 August 2023

There is a growing interest in tissue engineering, in which biomaterials play a pivotal role in promoting bone regeneration. Furthermore, smart functionalization can provide biomaterials with the additional role of preventing orthopedic infections. D...