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  • Article
  • Open Access
1 Citations
2,414 Views
10 Pages

Parental Stress in a Pediatric Ophthalmology Population

  • Sachin Kalarn,
  • Clare DeLaurentis,
  • Zaid Bilgrami,
  • Ryan Thompson,
  • Osamah Saeedi,
  • Janet Alexander,
  • Mary Louise Collins,
  • Allison Jensen,
  • Le Tran Notarfrancesco and
  • Moran Levin

26 October 2023

To determine the rate of parental stress within a pediatric ophthalmology population, parents in an urban or suburban community pediatric ophthalmology clinic were administered the Parental Stress Index Short Form survey. Demographic information and...

  • Review
  • Open Access
1 Citations
2,427 Views
23 Pages

Management of Retinoblastoma: A Challenge in Pediatric Ophthalmology

  • Claudia Carolina Cruz-Gálvez,
  • Víctor Manuel Villar-Calvo,
  • Juan Carlos Ordaz-Favila,
  • Martha Edith Cancino-Marentes,
  • Ximena García-Vicera,
  • Tannia Isabel Campos-Bayardo and
  • Vanessa Bosch-Canto

1 April 2026

Retinoblastoma (Rb) is the most common intraocular malignancy. If left untreated, Rb can result in death within 1–2 years. However, with timely detection and proper treatment, the survival rate is as high as 98%. The primary goal of Rb treatmen...

(This article belongs to the Special Issue Eye Diseases: Diagnosis and Treatment, 3rd Edition)
  • Article
  • Open Access
748 Views
22 Pages

Combining Process Mining and Simulation for Outpatient Pediatric Ophthalmology: A Case Study

  • Evelyn Salas,
  • Michael Arias,
  • Juan Diego Rodríguez,
  • Macarena Silva,
  • Arturo Solís,
  • Carla Fernández-Corrales and
  • Eric Rojas

13 July 2026

Process mining (PM) and process simulation (PS) are key disciplines for analyzing, optimizing, and improving processes to support decision-making. In recent years, the healthcare sector has significantly increased the adoption of PM tools and has sho...

(This article belongs to the Special Issue Process Mining: Theory and Applications)
  • Article
  • Open Access
2 Citations
2,531 Views
11 Pages

The Benefits of Badminton in the Inhibition of Myopia Progression

  • Joanna Zawistowska,
  • Wojciech Pawłowski,
  • Dominik Maślach,
  • Michalina Krzyżak,
  • Katarzyna Rogulska,
  • Julia Zawistowska,
  • Aneta Narel and
  • Alina Bakunowicz-Łazarczyk

1 May 2025

Background: Myopia progression in children is a growing public health concern, with increasing evidence suggesting that lifestyle factors may influence its development. This study aimed to evaluate the potential benefits of regular badminton activity...

(This article belongs to the Section Physiology and Pathology)
  • Systematic Review
  • Open Access
372 Views
15 Pages

21 August 2026

Background: Isolated sphenoid sinus disease (ISSD) in children is an uncommon but clinically significant condition that may present primarily with neurological or neuro-ophthalmological symptoms rather than typical sinonasal complaints. Owing to the...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Case Report
  • Open Access
10 Citations
3,821 Views
7 Pages

Novel Mutation in CRYBB3 Causing Pediatric Cataract and Microphthalmia

  • Olivia A. Zin,
  • Luiza M. Neves,
  • Fabiana L. Motta,
  • Dafne D. G. Horovitz,
  • Leticia Guida,
  • Leonardo H. F. Gomes,
  • Daniela P. Cunha,
  • Ana Paula S. Rodrigues,
  • Andrea A. Zin and
  • Zilton F. M. Vasconcelos
  • + 1 author

13 July 2021

Up to 25% of pediatric cataract cases are inherited, with half of the known mutant genes belonging to the crystallin family. Within these, crystallin beta B3 (CRYBB3) has the smallest number of reported variants. Clinical ophthalmological and genetic...

(This article belongs to the Collection Study on Genotypes and Phenotypes of Pediatric Clinical Rare Diseases)
  • Article
  • Open Access
7 Citations
3,709 Views
13 Pages

9 February 2023

There is limited evidence concerning the association between air pollution and different outpatient visits in moderately polluted areas. This paper investigates the effects of moderate-level air pollution on outpatient visits associated with six cate...

(This article belongs to the Section Human Toxicology and Epidemiology)
  • Article
  • Open Access
1 Citations
1,034 Views
23 Pages

17 December 2025

Purpose: Current pediatric ophthalmology practice relies on adult reference values for optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) interpretation due to limited age-appropriate normative data, potentially l...

(This article belongs to the Section Personalized Therapy in Clinical Medicine)
  • Review
  • Open Access
1 Citations
815 Views
18 Pages

Clinical Value of Optical Coherence Tomography in Craniopharyngioma

  • Klaudia Rakusiewicz-Krasnodębska,
  • Agnieszka Bogusz-Wójcik,
  • Anna Chmielarz-Czarnocińska,
  • Elżbieta Moszczyńska and
  • Wojciech Hautz

23 March 2026

Craniopharyngioma (CP) is a rare benign tumor of the sellar and suprasellar region that often compresses the optic pathways, causing significant visual impairment in both children and adults. The early detection and monitoring of optic nerve involvem...

(This article belongs to the Special Issue Advanced Diagnostics and Optical Imaging Technologies in Cancer Research)
  • Article
  • Open Access
3 Citations
5,316 Views
11 Pages

Pediatric and Juvenile Strabismus Surgery Under General Anesthesia: Functional Outcomes and Safety

  • Jakob Briem,
  • Sandra Rezar-Dreindl,
  • Lorenz Wassermann,
  • Katharina Eibenberger,
  • Franz Pusch,
  • Ursula Schmidt-Erfurth and
  • Eva Stifter

8 February 2025

Background/Objectives: The aim of this paper was to evaluate the safety of surgical intervention using anesthesia and ophthalmological parameters in pediatric strabismus patients. The design involved retrospective case series. Methods: The setting wa...

(This article belongs to the Section Ophthalmology)
  • Case Report
  • Open Access
2,625 Views
8 Pages

Neovascular Glaucoma as the First Symptom of Bilateral Occlusive Retinal Vasculitis in a 4-Year-Old Girl: A Case Report

  • Klaudia Rakusiewicz-Krasnodębska,
  • Joanna Jędrzejczak-Młodziejewska,
  • Krystyna Kanigowska and
  • Wojciech Hautz

Neovascular glaucoma is a rare and serious condition typically associated with advanced ocular or systemic vascular diseases such as central retinal vein occlusion or diabetic retinopathy. This report describes a unique case of neovascular glaucoma p...

(This article belongs to the Special Issue Microcirculation in Health and Diseases)
  • Interesting Images
  • Open Access
401 Views
6 Pages

Idiopathic Foveal Cavitation in a Pediatric Patient: Multimodal Imaging Findings Mimicking Early Macular Hole Formation

  • Bogumiła Wójcik-Niklewska,
  • Zofia Oliwa,
  • Karina Dzięcioł,
  • Mikołaj Gołda and
  • Adrian Smędowski

Macular holes are uncommon in pediatric patients and are most often associated with ocular trauma. Idiopathic cases are rare and may present as subtle clinical findings and atypical imaging features. We report a case of a 13-year-old boy presenting w...

(This article belongs to the Collection Interesting Images)
  • Article
  • Open Access
4 Citations
6,289 Views
17 Pages

Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study

  • Sonia Bianchini,
  • Chiara Morini,
  • Laura Nicoletti,
  • Sara Monaco,
  • Erika Rigotti,
  • Caterina Caminiti,
  • Giorgio Conti,
  • Maia De Luca,
  • Daniele Donà and
  • on Behalf of the Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group
  • + 15 authors

Ocular surgery encompasses a wide range of procedures, including surgery of the tear ducts, eyelid, cornea and conjunctiva, lens, ocular muscle, and vitreoretinal and iris surgery. Operations are also performed for the removal of tumors, repairs of o...

(This article belongs to the Special Issue Antimicrobial Use in Pediatrics)
  • Interesting Images
  • Open Access
2 Citations
673 Views
4 Pages

Ocular Involvement in a Pediatric Patient with Geleophysic Dysplasia

  • Bogumiła Wójcik-Niklewska,
  • Zofia Oliwa,
  • Paulina Sawuła and
  • Adrian Smędowski

Geleophysic dysplasia (GD) is a rare genetic skeletal disorder belonging to the acromelic group, characterized by short stature, distinctive facial features, thickened skin, and progressive cardiac involvement. We report a case of a 3-year-old boy wi...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Interesting Images
  • Open Access
661 Views
4 Pages

Pigmentary Retinopathy in Alagille Syndrome: Fundus Findings in a Two-Year-Old Boy

  • Bogumiła Wójcik-Niklewska,
  • Zofia Oliwa,
  • Karina Dzięcioł and
  • Adrian Smędowski

Alagille syndrome (ALGS) is a rare autosomal dominant multisystem disorder characterized by bile duct paucity, congenital heart defects, characteristic facial features, skeletal anomalies, and distinctive ocular findings. Although anterior segment an...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
1,300 Views
11 Pages

20 October 2025

Objectives: To develop a proof-of-concept machine learning (ML) neural network model to predict post-operative visual outcomes in children with congenital cataracts undergoing intraocular lens (IOL) implantation, thereby guiding the optimal timing fo...

(This article belongs to the Section Pediatric Ophthalmology)
  • Article
  • Open Access
10 Citations
7,919 Views
5 Pages

30 November 2022

Vision therapy, also known as behavioral therapy, is theorized by its practitioners to treat a variety of visual disorders, including learning disability in children. However, the utility of vision therapy to treat various learning disabilities is ch...

(This article belongs to the Special Issue Advances in Pediatric Ophthalmology)
  • Article
  • Open Access
1,157 Views
25 Pages

Parental Stress, Maternal Health, and Children’s Vision-Related Quality of Life in Total Childhood Blindness: A Cross-Sectional Study

  • Julio Cesar Souza-Silva,
  • Viviane Matias da Costa Souza,
  • Thallita de Freitas Ramos,
  • Cleusa Alves Martins,
  • Edinamar Aparecida Santos da Silva,
  • Marco Túlio Antônio Garciazapata,
  • Milton Ruiz Alves and
  • Maria Alves Barbosa

Parental stress is a critical yet understudied dimension of childhood total blindness, a condition that imposes substantial developmental, emotional, and functional challenges on families. This cross-sectional study assessed parenting stress, materna...

(This article belongs to the Section Behavioral and Mental Health)
  • Perspective
  • Open Access
19 Citations
6,990 Views
10 Pages

Retinopathy of Prematurity in the 21st Century and the Complex Impact of Supplemental Oxygen

  • Sarah H. Rodriguez,
  • Anna L. Ells,
  • Michael P. Blair,
  • Parag K. Shah,
  • C. Armitage Harper,
  • Maria Ana Martinez-Castellanos,
  • S. Grace Prakalapakorn,
  • Erima Denis,
  • Rebecca C. Lusobya and
  • Lucy Namakula
  • + 5 authors

3 February 2023

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. Not only do the epidemiologic determinants and distributions of patients with ROP vary worldwide, but clinical differences have also been described. The Third Edition of the...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
12 Citations
3,410 Views
27 Pages

Whole Exome Sequencing of 20 Spanish Families: Candidate Genes for Non-Syndromic Pediatric Cataracts

  • Patricia Rodríguez-Solana,
  • Natalia Arruti,
  • María Nieves-Moreno,
  • Rocío Mena,
  • Carmen Rodríguez-Jiménez,
  • Marta Guerrero-Carretero,
  • Juan Carlos Acal,
  • Joana Blasco,
  • Jesús M. Peralta and
  • Elena Vallespín
  • + 9 authors

Non-syndromic pediatric cataracts are defined as opacification of the crystalline lens that occurs during the first years of life without affecting other organs. Given that this disease is one of the most frequent causes of reversible blindness in ch...

(This article belongs to the Special Issue The Molecular and Cellular Basis of Eye Diseases: Cataract, PCO and ERM Formation)
  • Article
  • Open Access
298 Views
9 Pages

Retinal Structural and Microvascular Findings During Novel NPR-B-Targeted Vosoritide Therapy in Children with Achondroplasia

  • Anıl Ağaçkesen,
  • Hasan Karakaş,
  • Hande Turan,
  • Elvan Bayramoğlu and
  • Olcay Evliyaoğlu

3 October 2026

Background: The aim of this study was to evaluate the short-term ocular findings during vosoritide therapy in children with achondroplasia using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: In this study, pediatric patients...

(This article belongs to the Section Ophthalmology)
  • Review
  • Open Access
23 Citations
26,815 Views
9 Pages

Pediatric Conjunctivitis: A Review of Clinical Manifestations, Diagnosis, and Management

  • Matthew J. Mahoney,
  • Ruegba Bekibele,
  • Sydney L. Notermann,
  • Thomas G. Reuter and
  • Emily C. Borman-Shoap

29 April 2023

Conjunctivitis is a common pediatric problem and is broadly divided into infectious and non-infectious etiologies. Bacterial conjunctivitis makes up the majority of cases in children and often presents with purulent discharge and mattering of the eye...

(This article belongs to the Special Issue Advances in Pediatric Ophthalmology)
  • Article
  • Open Access
426 Views
16 Pages

Association Between Pediatric Obesity and Ocular Structural Parameters: A Cross-Sectional Study

  • Alev Koçkar,
  • Ahmet Oran,
  • Ayşe Nurcan Cebeci and
  • Elvan Alper Şengül

23 June 2026

Background/Objectives: To explore potential associations between pediatric obesity and retinal and anterior segment ocular structures using OCT and ocular biometry. This study was designed as an exploratory, hypothesis-generating analysis without a p...

(This article belongs to the Section Global Pediatric Health)
  • Case Report
  • Open Access
2,080 Views
13 Pages

Background/Objectives: A direct link between sensory processing disorder (SPD) and strabismus has not been systematically investigated, though prior studies suggest sensory modulation may influence visual behaviors. Traditional approaches view strabi...

(This article belongs to the Special Issue Children with Specific Neurodevelopmental Disorders: Assessment and Intervention (2nd Edition))
  • Interesting Images
  • Open Access
557 Views
4 Pages

Macular Hemorrhage as the First Manifestation of Leukemia

  • Bogumiła Wójcik-Niklewska,
  • Natalia Kwasniewska and
  • Adrian Smędowski

Acute lymphoblastic leukemia (ALL) is a malignant neoplasm of the blood and bone marrow characterized by the uncontrolled proliferation of precursor cells of B- or T-lymphocyte lineage. Usually, the disease arises because of spontaneous mutations in...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
8 Citations
2,912 Views
11 Pages

Clinical Features of Infectious Uveitis in Children Referred to a Hospital-Based Eye Clinic in Italy

  • Maria Pia Paroli,
  • Lucia Restivo,
  • Eleonora Ottaviani,
  • Chiara Nardella,
  • Irene Abicca,
  • Luca Spadea and
  • Marino Paroli

18 November 2022

Background and Objectives: To investigate the etiology, clinical features, ocular complications, and visual outcomes in children with infectious uveitis referred to a tertiary uveitis hospital-based service. Materials and Methods: Children with infec...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
8 Citations
4,168 Views
10 Pages

15 September 2022

Aims: To investigate the success rate of oral fluorescein angiography (oral FA) in children with ultrawide scanning laser ophthalmoscopy (SLO) system and whether it can provide images of sufficient quality compared with intravenous FA (IVFA). Methods...

(This article belongs to the Special Issue State-of-the-Art Research on Vitreoretinal Disorders)
  • Article
  • Open Access
1,393 Views
12 Pages

17 December 2025

Background/Objectives: Early detection and timely treatment of amblyopia require reliable visual acuity testing in toddlers; however, conventional Landolt ring charts often show poor testability in 2–3-year-old children. Therefore, we aimed to...

  • Article
  • Open Access
2 Citations
2,574 Views
13 Pages

Visual Health in Autism Spectrum Disorder: Screening Outcomes, Clinical Associations, and Service Gaps

  • Emine Tınkır Kayıtmazbatır,
  • Hasan Ali Güler,
  • Şule Acar Duyan,
  • Ayşe Bozkurt Oflaz and
  • Banu Bozkurt

1 October 2025

Background and Objectives: Children with autism spectrum disorder (ASD) often experience visual problems, yet their ophthalmic health remains underexplored due to testability challenges and limited-service access. This study evaluated ophthalmic scre...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
7 Citations
3,077 Views
7 Pages

25 May 2024

Background: Refractive errors, including myopia, hyperopia, and astigmatism, are the leading causes of visual impairment in school-aged children and can significantly impact their academic performance and quality of life. This study aimed to assess t...

(This article belongs to the Special Issue Advanced Research in Myopia and Other Visual Disorders)
  • Article
  • Open Access
4 Citations
5,486 Views
11 Pages

27 March 2024

The purpose of this study was to develop a new pediatric acuity chart that can assess the minimum separation threshold by incorporating the minimum separation threshold into the picture. To overcome the design limitations of the Landolt ring, two des...

(This article belongs to the Special Issue Visual Deficits and Eye Care in Children)
  • Article
  • Open Access
15 Citations
3,753 Views
12 Pages

OCT-Angiography Findings in Patients with Amblyopia: Comparison between Healthy Controls, Treatment-Responsive, and Treatment-Unresponsive Amblyopic Patients

  • Annabella Salerni,
  • Gloria Gambini,
  • Chiara Fedeli,
  • Ludovica Paris,
  • Emanuele Crincoli,
  • Gustavo Savino,
  • Maria Cristina Savastano,
  • Daniela Bacherini,
  • Umberto De Vico and
  • Stanislao Rizzo
  • + 2 authors

24 September 2021

There is no consensus on whether amblyopia affects the retinal vascular plexus and morphology. Previous studies focused on the differences between amblyopic patients and normal controls without evaluating amblyopic eyes after patching. To evaluate di...

(This article belongs to the Special Issue Optical Coherence Tomography Angiography (OCTA) as a New Diagnostic Tool in Ocular and Systemic Diseases)
  • Case Report
  • Open Access
1,945 Views
8 Pages

Background: Metachromatic leukodystrophy (MLD) is a rare autosomal recessive disorder that causes demyelination of both the central (CNS) and peripheral nervous systems (PNS). Objective: This study aims to report a unique MLD case presenting with cra...

  • Case Report
  • Open Access
5 Citations
3 Pages

Orbital emphysema is commonly associated with fractures of the orbital floor or medial wall. The air often dissipates spontaneously, but rarely can cause increased intraocular pressure and even loss of vision. Entrapment of the extraocular muscles ca...

  • Article
  • Open Access
11 Citations
3,305 Views
12 Pages

18 September 2024

Background: The purpose of this study is to evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMSs) in slowing myopia progression in pediatric patients as a function of age. Methods: This was a non-randomized experimenter-masked...

  • Article
  • Open Access
2 Citations
3,037 Views
16 Pages

Management of Bilateral Congenital and Juvenile Cataracts in a Low-Income Country: Patient Identification, Treatment Outcomes, and Follow Up

  • Broder Poschkamp,
  • Serge Dinkulu,
  • Thomas Stahnke,
  • Clara Böckermann,
  • Edith Mukwanseke,
  • Christiane Paschke,
  • Adrian Hopkins,
  • Rainald Duerksen,
  • Ellen Catrin Steinau and
  • Ngoy-Janvier Kilangalanga
  • + 3 authors

30 August 2024

Background: Childhood blindness remains a neglected issue in eye care within low-income countries, with congenital and juvenile cataracts being the most common treatable causes. This study aims to investigate the factors influencing the management of...

(This article belongs to the Section Pediatric Ophthalmology)
  • Review
  • Open Access
2 Citations
4,222 Views
25 Pages

23 October 2024

Inherited retinal diseases (IRDs) are a clinically and genetically diverse group of progressive degenerative disorders that can result in severe visual impairment or complete blindness. Despite their predominantly monogenic inheritance patterns, the...

(This article belongs to the Special Issue Retinal Diseases: From Molecular Mechanisms to Therapeutics)
  • Article
  • Open Access
3 Citations
2,921 Views
10 Pages

Evaluation of the Effect of Body Mass Index and Waist Circumference on Ocular Health Parameters in Children and Adolescents

  • İrfan Uzun,
  • Enes Colak,
  • Zeliha Atlıhan,
  • Çağrı Mutaf,
  • Ali Hakim Reyhan and
  • Funda Yüksekyayla

26 March 2025

Background/Objectives: Childhood obesity is a significant health concern also capable of impacting ocular health. This study evaluates the effects of childhood obesity on corneal morphology, anterior chamber parameters, intraocular pressure (IOP), an...

(This article belongs to the Section Pediatric Ophthalmology)
  • Article
  • Open Access
661 Views
17 Pages

Development and Diagnostic Accuracy of a Novel Screening Tool for Early Detection of Pediatric Visual Impairment in Indonesian School-Aged Children

  • Arya Ananda Indrajaya Lukmana,
  • Tri Rahayu,
  • Kianti Raisa Darusman,
  • Ray Wagiu Basrowi and
  • Nila Djuwita F. Moeloek

Background/Objectives: Uncorrected refractive errors (UREs) are a primary cause of preventable visual impairment in children globally, impacting education and quality of life. In Jakarta, prevalence has surged to 40% post-pandemic, categorizing it as...

  • Article
  • Open Access
323 Views
25 Pages

Age-Dependent Retinal Parameter Correlation Patterns on OCT and OCT Angiography in Children and Adults

  • Claudia Lommatzsch,
  • Antoine Capucci,
  • Swaantje Grisanti,
  • Carsten Heinz and
  • Kai Rothaus

19 June 2026

Background/Objectives: Optical coherence tomography (OCT) and OCT angiography (OCT-A) provide detailed measurements of retinal structure and vasculature; however, age-related differences in how these parameters correlate with one another remain poorl...

(This article belongs to the Special Issue Pediatric Ophthalmology: Current Progress and Future Options)
  • Case Report
  • Open Access
161 Views
9 Pages

Severe Pediatric Ocular Surface Disease: Multimodal Approach and Treatment

  • Laura Vilaverde,
  • Bruno B. Ribeiro,
  • Ricardo Parreira,
  • Miguel Gomes,
  • Pedro Menéres and
  • Irene Barbosa

Background/Objectives: Pediatric ocular surface disease associated with ocular rosacea, chronic blepharitis and meibomian gland dysfunction may result in significant corneal morbidity. In refractory cases, the limitations of conventional therapy have...

  • Article
  • Open Access
17 Citations
9,430 Views
11 Pages

Thicker Retinal Nerve Fiber Layer with Age among Schoolchildren: The Hong Kong Children Eye Study

  • Xiu-Juan Zhang,
  • Yi-Han Lau,
  • Yu-Meng Wang,
  • Hei-Nga Chan,
  • Poemen P. Chan,
  • Ka-Wai Kam,
  • Patrick Ip,
  • Wei Zhang,
  • Alvin L. Young and
  • Jason C. Yam
  • + 3 authors

15 February 2022

This study aims to investigate the effect of age on the peripapillary retinal nerve fiber layer (p-RNFL) thickness among schoolchildren. A total of 4034 children aged 6–8 years old received comprehensive ophthalmological examinations. p-RNFL th...

(This article belongs to the Special Issue Eye Diseases: Diagnosis and Management)
  • Article
  • Open Access
13 Citations
3,095 Views
11 Pages

Psychological Effects and Quality of Life in Parents and Children with Jia-Associated Uveitis

  • Silvana Guerriero,
  • Roberta Palmieri,
  • Francesco Craig,
  • Francesco La Torre,
  • Valeria Albano,
  • Gianni Alessio,
  • Massimo Corsalini,
  • Paola Lecce and
  • Andrea De Giacomo

30 November 2022

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory disease common in children and young adults. Uveitis is the most frequent serious extra-articular JIA manifestation and can lead to severe ocular complications, vision loss, and permanent...

  • Article
  • Open Access
4,368 Views
9 Pages

Purpose: This retrospective study aimed to compare the efficacy of cycloplegic (CR) versus non-cycloplegic refraction (NCR) methods in detecting refractive errors among children and adolescents. Methods: Electronic data from pediatric ophthalmology c...

  • Communication
  • Open Access
9 Citations
3,855 Views
6 Pages

Incidence of Ophthalmological Complications in NF-1 Patients Treated with MEK Inhibitors

  • Lena Hummel,
  • May Ameri,
  • Shaikha Alqahtani,
  • Zsila Sadighi and
  • Nagham Al-Zubidi

7 May 2024

MEK inhibitors (MEKi) represent innovative and promising treatments for managing manifestations of neurofibromatosis type 1 (NF1). To mitigate potential ophthalmic side effects, such as MEKi-associated retinopathy (MEKAR), patients undergoing MEKi th...

  • Article
  • Open Access
1 Citations
2,209 Views
10 Pages

Acute Pupillary Disorders in Children: A 10-Year Retrospective Study of 101 Patients

  • Giacomo Garone,
  • Marco Roversi,
  • Mara Pisani,
  • Francesco La Penna,
  • Antonio Musolino,
  • Sebastian Cristaldi,
  • Anna Maria Musolino,
  • Amanda Roberto,
  • Gianni Petrocelli and
  • Umberto Raucci
  • + 3 authors

26 October 2023

Background: To date, no study has specifically examined children with acute-onset pupillary motility disorders (APMD). Especially in the Emergency Department (ED), it is crucial to distinguish benign and transient conditions from life-threatening or...

(This article belongs to the Special Issue Pediatric Emergency Medicine)
  • Review
  • Open Access
13 Citations
4,307 Views
32 Pages

Advancements in Nanosystems for Ocular Drug Delivery: A Focus on Pediatric Retinoblastoma

  • Kevin Y. Wu,
  • Xingao C. Wang,
  • Maude Anderson and
  • Simon D. Tran

The eye’s complex anatomical structures present formidable barriers to effective drug delivery across a range of ocular diseases, from anterior to posterior segment pathologies. Emerging as a promising solution to these challenges, nanotechnolo...

(This article belongs to the Special Issue Nanostructured Materials: Synthesis, Functionalization and Applications in Biomedicine)
  • Feature Paper
  • Article
  • Open Access
1 Citations
1,346 Views
14 Pages

Advancing Non-Invasive Ophthalmic Imaging in Sturge–Weber Syndrome: Clinical Guidelines Towards Early Choroidal Hemangioma Detection

  • Mariachiara Di Pippo,
  • Daria Rullo,
  • Chiara Ciancimino,
  • Flaminia Grassi,
  • Alessandro Ferretti,
  • Pasquale Parisi,
  • Giovanni Di Nardo,
  • Alessandro Orsini,
  • Marco Perulli and
  • Solmaz Abdolrahimzadeh
  • + 2 authors

3 October 2025

Background/Objectives: Sturge–Weber syndrome (SWS) is a rare neuro-oculocutaneous disorder characterized by leptomeningeal angioma, naevus flammeus, and ocular manifestations, including diffuse choroidal hemangioma (DCH). This study compares th...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
3 Citations
6,293 Views
11 Pages

14 February 2023

Headache is the most common neurologic complaint that presents to the pediatrician. While most headaches are benign in nature, patients must be carefully evaluated to rule out life- or vision-threatening causes. Non-benign etiologies of headache may...

(This article belongs to the Special Issue Advances in Pediatric Ophthalmology)
  • Article
  • Open Access
365 Views
9 Pages

Outcomes of Strabismus Surgery in Pediatric Hydrocephalus: Does Shunting Influence Surgical Success?

  • Didem Dizdar Yigit,
  • Sule Nur Kandemir,
  • Volkan Dericioglu,
  • Furkan Cam,
  • Yener Sahin,
  • Eren Cerman,
  • Adnan Dagcinar and
  • Hande Celiker

3 August 2026

Background/Objectives: The primary aim of this study was to evaluate the rate of strabismus and surgical outcomes in pediatric hydrocephalus (HC) patients, and compare the results in patients with and without ventriculoperitoneal (VP) shunt surgery....

(This article belongs to the Section Pediatric Ophthalmology)

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