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37 pages, 555 KB  
Article
Jihād and the Protection of Places of Worship in Early Islam: Between Covenant, Conquest, and a Just Peace
by Halim Rane, Ibrahim Zein and Ahmed El-Wakil
Religions 2026, 17(1), 86; https://doi.org/10.3390/rel17010086 - 12 Jan 2026
Abstract
This article examines the relationship between jihād and the protection of non-Muslim places of worship in early Islam. Drawing primarily on Qurʾānic verses 22:39–41 and the Covenants of the Prophet, it employs a synchronically comparative framework that analyzes a broad corpus of textual [...] Read more.
This article examines the relationship between jihād and the protection of non-Muslim places of worship in early Islam. Drawing primarily on Qurʾānic verses 22:39–41 and the Covenants of the Prophet, it employs a synchronically comparative framework that analyzes a broad corpus of textual sources, seeking to reconstruct how the early Muslim worldview understood the justification for jihād. It also examines the norms governing conduct after conflict, particularly in relation to treaty-making. The article attempts to make sense of Q22:39–41 within the broader landscape of late antiquity, which was marked by religious persecution and the destruction of sanctuaries under Byzantine and Sasanian rule. The study highlights how clear rules of engagement were articulated in early Islam, including limits on violence and the consequences of treaty violation. It argues that the motivations behind the early conquests cannot be reduced to material interests but rather were guided by a theological and ideological vision linking conquest with the establishment of a just peace, one grounded in the protection of communities, faith, and places of worship through a covenantal paradigm. Full article
27 pages, 653 KB  
Review
Learning to Be Human: Forming and Implementing National Blends of Transformative and Holistic Education to Address 21st Century Challenges and Complement AI
by Margaret Sinclair
Educ. Sci. 2026, 16(1), 107; https://doi.org/10.3390/educsci16010107 - 12 Jan 2026
Abstract
The paper introduces ‘transformative’ curriculum initiatives such as education for sustainable development (ESD) and global citizenship education (GCED), which address ‘macro’ challenges such as climate change, together with ‘holistic’ approaches to student learning such as ‘social and emotional learning’ (SEL) and education for [...] Read more.
The paper introduces ‘transformative’ curriculum initiatives such as education for sustainable development (ESD) and global citizenship education (GCED), which address ‘macro’ challenges such as climate change, together with ‘holistic’ approaches to student learning such as ‘social and emotional learning’ (SEL) and education for ‘life skills’, ‘21st century skills’, ‘transversal competencies’, AI-related ethics, and ‘health and well-being.’ These are reflected in Section 6 of the 2023 UNESCO Recommendation on Education for Peace, Human Rights and Sustainable Development. It is suggested that such broad goals put forward at global policy level may serve as inspiration for national context-specific programming, while also needing better integration of national insights and cultural differences into global discourse. The paper aims to provide insights to education policy-makers responsible for national curriculum, textbooks and other learning resources, teacher training and examination processes, helping them to promote the human values, integrity and sense of agency needed by students in a time of multiple global and personal challenges. This requires an innovative approach to curricula for established school subjects and can be included in curricula being developed for AI literacy and related ethics. Research into the integration of transformative and holistic dimensions into curricula, materials, teacher preparation, and assessment is needed, as well as ongoing monitoring and feedback. AI-supported networking and resource sharing at local, national and international level can support implementation of transformative and holistic learning, to maintain and strengthen the human dimensions of learning. Full article
24 pages, 18899 KB  
Article
Network Pharmacology of the Phytochemical Content of Sunflower Seed (Helianthus annuus L.) Extract from LC-MS on Wound-Healing Activity and the In Vitro Wound Scratch Assay
by Juthamat Ratha, Tanit Padumanonda, Chawalit Yongram, Pimolwan Siriparu, Suthida Datham, Muhammad Subhan, Chatchavarn Chenboonthai and Ploenthip Puthongking
Plants 2026, 15(2), 187; https://doi.org/10.3390/plants15020187 - 7 Jan 2026
Viewed by 293
Abstract
Sunflower seeds have been reported to be a healthy natural source of polyphenols. This study aimed to explore the mechanisms of potential compounds in sunflower seed extract involved in wound healing; major compounds were investigated through network pharmacology and molecular docking. In an [...] Read more.
Sunflower seeds have been reported to be a healthy natural source of polyphenols. This study aimed to explore the mechanisms of potential compounds in sunflower seed extract involved in wound healing; major compounds were investigated through network pharmacology and molecular docking. In an in vitro wound-healing assay applied using an immortalised human keratinocyte (HaCaT) cell model, 10 µg/mL of the sunflower seed extract promoted cell migration in HaCaT cells and led to complete wound closure after 24 h; at a 1 µg/mL concentration, it led to complete wound closure after 72 h. The sunflower seed extract presented moderate-to-strong antioxidant activity. Liquid chromatography–mass spectrometry and high-performance liquid chromatography were used to identify the major compounds present in the sunflower seed extract. Forty-seven compounds were identified, among which chlorogenic acid was the most abundant phenolic compound. Network pharmacology was used to identify wound-healing-related targets. In total, 252 proteins were linked to the 47 compounds. Cyto-Hubba analysis identified 10 hub proteins with a strong correlation with wound healing. Molecular docking was used to assess the ability of the major compounds in the sunflower seed extract to combat NF-κB1, EGFR, and MMP9. Chlorogenic acid showed higher binding affinity to all targets. Moreover, its pharmacokinetic properties were well distributed in the plasma (VDss = 0.377 log L/kg), and they were not a carcinogen and did not cause skin sensitisation. In conclusion, the findings suggest that the sunflower seed extract is a potential source of bioactive compounds that can enhance wound healing and can be developed to create a transdermal application. Full article
(This article belongs to the Section Phytochemistry)
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13 pages, 230 KB  
Article
How Local Is Islam Nusantara? Questions of Tolerance and Authenticity
by Jochem W. P. van den Boogert
Religions 2026, 17(1), 65; https://doi.org/10.3390/rel17010065 - 7 Jan 2026
Viewed by 142
Abstract
Especially over the last two and a half decades, Indonesian society has witnessed a deepening Islamisation, the impact of which is being felt in domains such as politics, education, morality, and private life. Linked to this development, a rise in religious intolerance and [...] Read more.
Especially over the last two and a half decades, Indonesian society has witnessed a deepening Islamisation, the impact of which is being felt in domains such as politics, education, morality, and private life. Linked to this development, a rise in religious intolerance and extremism has been noted. This process is often attributed to influences from transnational movements such as the Muslim Brotherhood and Salafi-Wahhabism, which in turn is framed as an Arabisation of Islam and society in Indonesia. A pivotal reaction has been the launch and successful reinforcement of the concept of Islam Nusantara, a local Islam that is described as peaceful, moderate, and tolerant. Its unique Indonesian history, in which local culture and Islam have become intertwined, is said to have led to these characteristics. Despite its success, the concept has also met with scepticism. How valid is the binary Arabian Islam versus Islam Nusantara? Is it an authentic form of Islam? This article engages with these issues from a new angle by combining an assessment of Islam Nusantara’s claims to tolerance, its status as an authentic form of Islam, and how these issues relate to it being a local Islam. Full article
31 pages, 1852 KB  
Article
Sentiment Analysis of X Users Regarding Bandung Regency Using Support Vector Machine
by Irlandia Ginanjar, Abdan Mulkan Shabir, Anindya Apriliyanti Pravitasari, Sinta Septi Pangastuti, Gumgum Darmawan and Sukono
Appl. Sci. 2026, 16(1), 560; https://doi.org/10.3390/app16010560 - 5 Jan 2026
Viewed by 129
Abstract
Social media has the potential to serve beneficial purposes. The abundance of uploaded content and responses from the public generates various opinions, allowing them to be identified as positive or negative regarding the portrayal of Bandung Regency. This research aims to analyse the [...] Read more.
Social media has the potential to serve beneficial purposes. The abundance of uploaded content and responses from the public generates various opinions, allowing them to be identified as positive or negative regarding the portrayal of Bandung Regency. This research aims to analyse the classification and frequency of words for each sentiment expressed by X (Twitter) users regarding Bandung Regency. The research employs the Support Vector Machine (SVM) method. We expect the results to aid in formulating governmental programmes for Bandung Regency. The research revealed that the SVM model, which uses the Sigmoid kernel function with parameters C = 10 and gamma (γ) = 1, is the most optimal sentiment classification model for handling an imbalanced dataset. This model achieved an 83.01% negative recall value. Furthermore, frequent words appearing in both classes indicate that several positive opinions about Bandung Regency exhibit similar dominance, except for football dominance in negative opinions. This research pertains to the United Nations Sustainable Development Goals (SDGs), particularly SDG 11 (Sustainable Cities and Communities) and SDG 16 (Peace, Justice, and Strong Institutions). The suggested technique facilitates evidence-based policy reviews, transparent governance, and enhanced responsive public services by analysing public sentiment regarding local government performance. The results illustrate how social media analytics can aid local governments in assessing popular sentiment and pinpointing areas for policy response. Full article
(This article belongs to the Special Issue Natural Language Processing and Text Mining)
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24 pages, 2852 KB  
Article
Valorizing Rice Husk Waste as a Biosorbent with Gamma-Induced Surface Modification for Enhanced Heavy-Metal Adsorption
by Kulthida Saemood, Siriphon Samutsan, Kasinee Hemvichian, Pattra Lertsarawut, Saowaluck Thong-In, Harinate Mungpayaban, Shinji Tokonami, Ryoma Tokonami, Tatsuhiro Takahashi and Kiadtisak Saenboonruang
Sustainability 2026, 18(1), 549; https://doi.org/10.3390/su18010549 - 5 Jan 2026
Viewed by 214
Abstract
This work investigated the effects of gamma irradiation on the adsorption capacities of rice husk (RH) for the removal of Cu2+, Cr3+, and Zn2+ ions from aqueous solutions, with potential applications in wastewater remediation. RH samples were gamma-irradiated [...] Read more.
This work investigated the effects of gamma irradiation on the adsorption capacities of rice husk (RH) for the removal of Cu2+, Cr3+, and Zn2+ ions from aqueous solutions, with potential applications in wastewater remediation. RH samples were gamma-irradiated at doses up to 40 kGy and characterized using SEM-EDS, XRF, FTIR, XRD, and BET analyses. While morphological and textural changes remained subtle, FTIR and SEM-EDS confirmed the formation and intensification of oxygen-containing functional groups, including –OH, –COOH, and C=O, as well as increased exposure of silica (Si–O) on the surfaces, which substantially enhanced surface reactivity of RH toward metal ions. Batch adsorption experiments revealed that 40-kGy irradiated RH samples (RH-40) exhibited the highest removal efficiencies compared to non-irradiated and lower-dose samples (RH-0, RH-10, RH-20, and RH-30), specifically with improvements of 415% for Cu2+, 502% for Cr3+, and 663% for Zn2+ compared to RH-0, determined at the initial concentration of 10 mg/L. Kinetic studies also showed rapid adsorption within the first 10–15 min, dominated initially by boundary-layer diffusion, followed by chemisorption-driven equilibrium behavior. The pseudo-second-order (PSO) model provided an excellent fit for all metals (R2 = 0.999), indicating maximum model-predicted kinetic capacities of 555.56 mg/g (Cu2+), 769.23 mg/g (Cr3+), and 434.78 mg/g (Zn2+). Langmuir isotherms also fitted well (R2 = 0.941–0.995), with predicted monolayer capacities of 535.33 mg/g (Cu2+), 491.64 mg/g (Cr3+), and 318.88 mg/g (Zn2+). Freundlich modeling further indicated favorable heterogeneous adsorption, with KF values of 42.614 (Zn2+), 20.443 (Cr3+), and 16.524 (Cu2+) and heterogeneity factors (n) greater than 1 for all metals. These overall results suggested that gamma irradiation substantially enhanced RH functionality that enabled fast and high-capacity heavy-metal adsorption through surface oxidation and carbon valorization. Gamma-irradiated RH, therefore, represented a promising, low-cost, and environmentally friendly biosorbent for wastewater treatment applications. Full article
(This article belongs to the Special Issue Sustainable Materials, Waste Management, and Recycling)
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17 pages, 3616 KB  
Article
Corporeity and Ecological Awareness: An Experiential Study with Children and Adolescents
by Marcos Vinícius G. De Paula, Pedro H. C. Schimmelpfeng, Luiz Gonzaga Lapa and Claudia Marcia Lyra Pato
Sustainability 2026, 18(1), 521; https://doi.org/10.3390/su18010521 - 5 Jan 2026
Viewed by 310
Abstract
Environmental Education (EE) is increasingly relevant in the current context of environmental crises, requiring approaches that integrate Human Ecology (HE) and Environmental Psychology (EP) due to understanding the interdependent relationship between ecological and human systems. This study emphasizes corporeity as a fundamental dimension [...] Read more.
Environmental Education (EE) is increasingly relevant in the current context of environmental crises, requiring approaches that integrate Human Ecology (HE) and Environmental Psychology (EP) due to understanding the interdependent relationship between ecological and human systems. This study emphasizes corporeity as a fundamental dimension for reconnecting humans with nature and fostering ecological awareness. The study aimed to develop and evaluate a transdisciplinary intervention project based on bodily experiences with children and adolescents in a Brazilian public school, aiming to improve their connectedness with nature and ecological values. A diagnostic survey was conducted with 103 students aged 10–13 years, including open questions, and two instruments: the Inclusion of Nature in Self (INS) and the Values for Pre-adolescents scale (EVP). The results indicated that one 5th-grade class, which presented the lowest self-transcendence mean (4.07), was selected for pedagogical interventions. In the second stage, 20 students participated in workshops held in public parks and a school green area, combining sensory awareness and playful activities. The findings suggest that these experiences stimulated pro-environmental attitudes, including group care for nature, protective behaviors, and positive emotions such as peace, happiness, and freedom. Despite the small sample size, the results highlight the importance of strengthening embodied experiences in natural environments, increasing frequency and intensity to support the development of ecological values and deeper connectedness with nature. Full article
(This article belongs to the Special Issue Motivating Pro-Environmental Behavior in Youth Populations)
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22 pages, 1868 KB  
Article
Exploratory Research on Factors Affecting User Satisfaction of an Urban Railway System in a Developing Country: The Case of Jakarta Mass Rapid Transit (MRT) in Indonesia
by Kei Endo, Yasushi Taira and Takumi Kanazuka
Urban Sci. 2026, 10(1), 19; https://doi.org/10.3390/urbansci10010019 - 1 Jan 2026
Viewed by 278
Abstract
Urban railway systems are critical for the daily lives of citizens in cities. Considering that urban railways are a core infrastructure, it is important for urban and railway practitioners to operate and maintain urban railway systems effectively and to maximize user satisfaction. However, [...] Read more.
Urban railway systems are critical for the daily lives of citizens in cities. Considering that urban railways are a core infrastructure, it is important for urban and railway practitioners to operate and maintain urban railway systems effectively and to maximize user satisfaction. However, despite the importance of this topic, research on the factors that contribute to high levels of railway user satisfaction in the context of Southeast Asian developing countries remains limited. To address this gap, this study conducted an exploratory case study using the Jakarta Mass Rapid Transit (MRT). This study collected 406 valid responses regarding Jakarta MRT user satisfaction through a face-to-face questionnaire survey and analyzed them using regression analysis, fuzzy-set qualitative comparative analysis (fsQCA), and text-mining techniques, which have seldom been applied in previous research on factors influencing railway user satisfaction. The results indicate that high levels of satisfaction with railway fares and social considerations—particularly the combination of both—may be the simplest configuration associated with higher overall user satisfaction, while various other combinations of satisfaction dimensions could also lead to elevated satisfaction. The results also suggest that all dimensions may serve as necessary and/or sufficient conditions for high satisfaction, implying the importance of considering all dimensions. These findings are specific to this case study and may differ depending on the socio-cultural contexts. To advance the understanding of satisfaction factors, further comparative research on the Jakarta MRT and rail systems in other countries is warranted. Full article
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15 pages, 296 KB  
Article
From Pyrrho to Sextus Empiricus: The Philosophical Roots of Postmodern Political Theory in Ancient Greek Skepticism
by Ziya Kıvanç Kıraç, Fırat Kargıoğlu and Oğuzhan Göktolga
Philosophies 2026, 11(1), 4; https://doi.org/10.3390/philosophies11010004 - 30 Dec 2025
Viewed by 295
Abstract
In this article, the philosophical (critical) continuity between ancient Greek skepticism (Pyrrhonism) and postmodern political theory is pointed out. This continuity (philosophical reincarnation) is demonstrated by referring to Sextus Empiricus’ writings on Pyrrhonism, as well as two different approaches that are considered to [...] Read more.
In this article, the philosophical (critical) continuity between ancient Greek skepticism (Pyrrhonism) and postmodern political theory is pointed out. This continuity (philosophical reincarnation) is demonstrated by referring to Sextus Empiricus’ writings on Pyrrhonism, as well as two different approaches that are considered to reflect postmodern political theory in its most salient features, such as anti-fundamentalism: Chantal Mouffe’s “project of radical democracy” and the “art of doubt” in Ulrich Beck’s “reflexive” modernity. The content of the identified continuity is basically the following: Just as the Pyrrhonian philosopher aspires to achieve serenity of spirit by suspending judgment through doubt (“epoche” and “ataraksia”) [epəkē –αταραξία], the postmodern theorist aims to end organized political violence by doubting all modern truth allegations. In other words, the individual hope of the Pyrrhonian philosopher is reproduced in the postmodern mind as a socio-political ideal. In Michel Foucault’s terms, the “regime of truth” or the “politics of truth” is an option that often leads to the “terror of truth”. The politics of doubt, on the other hand, is a peaceful, tolerant alternative. According to the postmodern theorist, skepticism is a highly strategic element of a pluralist (libertarian) democratic order. The intellectual way to make modern democracy even more democratic is, first and foremost, through a skepticism that makes absolutely no concessions to truth allegations. In this respect, the most uncompromising skeptic in the history of philosophy is the Pyrrhonian philosopher. Pyrrhonism is the summit of anti-dogmatism. This means that the postmodern theorist is not so much a postmodern agent. In other words, postmodern political theory is the theory of an innovation that is already obsolete. Full article
17 pages, 366 KB  
Article
Deo Parere Libertas Est: Stoic Echoes in Wittgenstein’s Conception of Destiny
by Begoña Ramón Cámara
Religions 2026, 17(1), 26; https://doi.org/10.3390/rel17010026 - 25 Dec 2025
Viewed by 304
Abstract
My aim in this paper is to examine some aspects of the relationship between the concepts of God, destiny, and happiness in Wittgenstein’s writings. The analysis is done—to use an expression of the philosopher’s own—by contrast with and against the background of Roman [...] Read more.
My aim in this paper is to examine some aspects of the relationship between the concepts of God, destiny, and happiness in Wittgenstein’s writings. The analysis is done—to use an expression of the philosopher’s own—by contrast with and against the background of Roman Stoicism’s views on this matter, mainly Epictetus, Seneca, and Marcus Aurelius. The different uses of the concept of God that appeared in their texts are analysed, and the relationship between the notions of destiny, self-sufficiency, and happiness is clarified. Several similarities between Wittgenstein and Roman Stoics are traced, among others, those relating to the sense of the principle of distinction between what depends on oneself and what does not, the primacy of inner life as an absolute alternative to the impossible mastery of the world of facts, and the ideas of a serene acceptance of adversity and of happiness as peace of mind. Full article
(This article belongs to the Special Issue New Work on Wittgenstein's Philosophy of Religion)
26 pages, 648 KB  
Article
The Protection of Flora in Wang Mang’s Edict and the Taiping jing in the Context of Disasters
by Johan Rols
Religions 2026, 17(1), 25; https://doi.org/10.3390/rel17010025 - 25 Dec 2025
Viewed by 548
Abstract
This article analyzes prohibitions against the destruction of flora in the calendrical regulations of the late Western Han period and in the millenarian cosmological discourses in the Taiping jing 太平經 (Canon of Great Peace). The study focuses on the “Zhaoshu sishi [...] Read more.
This article analyzes prohibitions against the destruction of flora in the calendrical regulations of the late Western Han period and in the millenarian cosmological discourses in the Taiping jing 太平經 (Canon of Great Peace). The study focuses on the “Zhaoshu sishi yueling wushi tiao” 詔書四時月令五十條 (“Edict of Monthly Ordinances for the Four Seasons in Fifty Articles”) which was promulgated by Wang Mang in 5 CE. The Edict prohibited setting fire to forests and was intended to restore cosmic harmony. At the time, natural disasters and celestial anomalies were interpreted as signs of the loss of the Mandate of Heaven. Heavenly patterns and hemerology play a central role here by enabling environmental regulations to be incorporated into a political logic of legitimization. The Canon of Great Peace reinterprets these norms by replacing seasonal cycles with an interpretation of balance between yin and yang and by giving environmental prohibitions eschatological significance. Thus, calendrical regulations for natural resource management transform into an apocalyptic discourse in which the natural environment becomes the setting for cosmic disorder that must be avoided. Full article
(This article belongs to the Special Issue The Diversity and Harmony of Taoism: Ideas, Behaviors and Influences)
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18 pages, 3850 KB  
Article
Ecological Monitoring of Nuclear Test Sites over 20 Years Based on Remote Sensing Ecological Index: A Case Study of the Semipalatinsk Test Site
by Aidana Sairike, Noriyuki Kawano, Vladisaya Bilyanova Vasileva and Mianwei Chen
Sustainability 2026, 18(1), 206; https://doi.org/10.3390/su18010206 - 24 Dec 2025
Viewed by 263
Abstract
The Semipalatinsk Test Site (STS), one of the most heavily contaminated nuclear test sites globally, presents critical challenges for ecological monitoring and restoration due to long-term radioactive pollution and soil degradation. This study applied the Remote Sensing Ecological Index (RSEI) model to systematically [...] Read more.
The Semipalatinsk Test Site (STS), one of the most heavily contaminated nuclear test sites globally, presents critical challenges for ecological monitoring and restoration due to long-term radioactive pollution and soil degradation. This study applied the Remote Sensing Ecological Index (RSEI) model to systematically evaluate the spatiotemporal changes in ecological quality at STS from 2003 to 2023. The RSEI model integrated multi-indicator data, including NDVI (Normalized Difference Vegetation Index), LST (Land Surface Temperature), WET (Wetness), and NDBSI (Normalized Difference Built-up and Soil Index), enabling a comprehensive assessment of ecological dynamics. Results demonstrated a significant improvement in ecological quality, with the RSEI increasing by 29.59% (from 0.345 in 2003 to 0.447 in 2023). PCA results indicated that ecological recovery was primarily influenced by surface temperature, vegetation cover, and soil moisture, with radioactive residues further hindering recovery in severely contaminated zones. The proportion of “Poor” areas declined from 14.99% to 0.61%, while “Moderate” and “Good” areas expanded to 55.76% and 8.87%, respectively. Peripheral regions showed faster recovery due to effective natural and management interventions, while core high-contamination zones (Sary-Uzen) exhibited slower recovery due to persistent radioactive residues. This study highlights the applicability of RSEI for assessing ecological recovery in nuclear test sites and emphasizes the need for targeted remediation strategies. These findings provide valuable insights for global ecological management of nuclear test sites, supporting sustainable restoration efforts. Full article
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31 pages, 608 KB  
Article
Correlations Between Depression Severity and Socioeconomic and Political Factors in Women over 50: A Longitudinal Study in Europe
by Lee Lusher, Samuel Giesser, David A. Groneberg and Stefanie Mache
Healthcare 2026, 14(1), 42; https://doi.org/10.3390/healthcare14010042 - 23 Dec 2025
Viewed by 464
Abstract
Background: With ageing populations and increasing labour force participation among women over 50, their mental health and psychological well-being require attention. The multifactorial etiology of depression has been extensively studied at both the individual and societal levels. Longitudinal analyses exploring socioeconomic and political [...] Read more.
Background: With ageing populations and increasing labour force participation among women over 50, their mental health and psychological well-being require attention. The multifactorial etiology of depression has been extensively studied at both the individual and societal levels. Longitudinal analyses exploring socioeconomic and political determinants and whether they influence depression severity across European countries are lacking. Objective: The objective of this study was to examine a possible correlation between socioeconomic and political factors with depression severity in women aged 50 and older in Europe and to what extent these possible correlations vary across countries. Methods: This longitudinal observational study was conducted using data from 47,426 women aged 50–89 years across 15 European countries, drawn from seven waves (2004–2015) of the Survey of Health, Ageing and Retirement in Europe (SHARE). Depression symptoms were measured by the validated European Depression Scale (EURO-D). The Andersen Model of Health Service Utilization was applied to contextualize twelve macro-level predictors of depression. These were organized into four overarching domains—health, education/employment/finance, equality, and security. Mean EURO-D scores were calculated with respect to age group and country. Correlations between predictors and depressive symptoms were assessed using Pearson’s and Adjusted Pearson’s correlation coefficients to determine the strength and rank of associations. Results: Significant correlations between predictor variables and depression were identified in nine countries, especially among women aged 80–89 years. Spain and Estonia showed strong predictors across several age groups. Eastern European countries exhibited the broadest range of significant correlations. Italy and France, despite high depression levels, revealed few significant predictors. Sweden, the Netherlands, and Switzerland had lower depression scores and demonstrated clearer correlations. Factors related to LGBTQ+ rights, perceived corruption, and peace indices emerged as influential. Conclusions: Country-specific historical, cultural, and sociopolitical factors appear to shape severity of depression in older women, with the strongest effects in the oldest age groups. Predictors of EURO-D scores varied by country and age group, with differences in explanatory power. The importance of predictors varied across age groups; listing them without context misrepresents the findings. The interplay between objective indicators and public perception, especially concerning minority rights and governance, highlights the need for culturally sensitive interventions. Future prevention efforts should incorporate these determinants to improve mental health across Europe. Full article
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13 pages, 1060 KB  
Article
Linking Silvics to Policy: A Disconnect with Free-to-Grow Standards in Northeast British Columbia
by Christopher Hawkins and Christopher Maundrell
Forests 2026, 17(1), 21; https://doi.org/10.3390/f17010021 - 23 Dec 2025
Viewed by 194
Abstract
Northeast British Columbia (54–60° N latitude, 120–123° W longitude) has 10+ M ha of complex conifer–broadleaf forest, which is a unique forest type in the province. Current management practice is to remove competing broadleaf species to promote the growth of more commercially valued [...] Read more.
Northeast British Columbia (54–60° N latitude, 120–123° W longitude) has 10+ M ha of complex conifer–broadleaf forest, which is a unique forest type in the province. Current management practice is to remove competing broadleaf species to promote the growth of more commercially valued conifers. This approach ignores the species silvics and results in forest simplification, thus reducing species and structural diversity, habitat value, and overall stand resilience to future events such as climate change and wildfires. These practices also negatively impact traditional First Nation treaty rights. Three trials were established across the region in 5-to-18-year-old post-logging mixed species stands where broadleaves had not been removed. Competition-free radii of 0, 1, 2, and 4 m were established around white spruce (Picea glauca (Moench) Voss) crop trees. The objective was to investigate the impact of broadleaf (aspen Populus tremuloides Michx. or paper birch Betula papyrifera Marsh.) competition on crop tree growth with respect to the free-to-grow (FTG) standard. Except at extreme broadleaf densities (>10,000 SPH), crop tree DBH growth was not impacted when trials were established. After at least 11 growing seasons, except at the competition-free 4 m radius, DBH was not impacted by competition. Spruce DBH in the mixed stand at all radii was greater than the expected BC model projections for a pure spruce stand on these sites. Our findings suggest that the current FTG management approach in northeast BC only has a positive result if taken to an extreme. It has a low return on investment and reduces stand resilience and total productivity. An alternative forest management approach for the region is presented. Full article
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15 pages, 1265 KB  
Review
The Evolving Role of Artificial Intelligence in Medical Genetics: Advancing Healthcare, Research, and Biosafety Management
by Ying-Cheng Wu, Nan Tuo, Guoming Shi, Ka Li, Zhenju Song and Yanying Li
Genes 2026, 17(1), 6; https://doi.org/10.3390/genes17010006 - 19 Dec 2025
Viewed by 724
Abstract
The integration of artificial intelligence (AI) with medical genetics is transforming healthcare by addressing the analytical challenges posed by the vast complexity of multi-omics data. This review explores the synergistic convergence of these fields, highlighting AI’s transformative role in enhancing diagnostic precision, enabling [...] Read more.
The integration of artificial intelligence (AI) with medical genetics is transforming healthcare by addressing the analytical challenges posed by the vast complexity of multi-omics data. This review explores the synergistic convergence of these fields, highlighting AI’s transformative role in enhancing diagnostic precision, enabling non-invasive molecular profiling through imaging-genetics, and advancing predictive and personalized medicine via polygenic risk scores and pharmacogenomics. AI is also emerging as a powerful generative tool in therapeutic design, accelerating drug discovery, protein engineering, and precision gene editing. However, this powerful synergy introduces significant ethical, regulatory, and biosecurity challenges, including data privacy, algorithmic bias, and the dual-use risks of AI-enabled genetic engineering. The future envisions a responsible co-evolution, with multimodal AI and the concept of the Digital Twin driving precision medicine, underpinned by interdisciplinary collaboration to ensure fairness, transparency, and societal trust. This article charts the current landscape and proposes actionable directions, emphasizing the need for robust governance to harness AI’s potential while mitigating its risks for the benefit of human health. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
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