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19 pages, 4767 KiB  
Article
Risk Mitigation of a Heritage Bridge Using Noninvasive Sensors
by Ricky W. K. Chan and Takahiro Iwata
Sensors 2025, 25(12), 3727; https://doi.org/10.3390/s25123727 - 14 Jun 2025
Viewed by 348
Abstract
Bridges are fundamental components of transportation infrastructure, facilitating the efficient movement of people and goods. However, the conservation of heritage bridges introduces additional challenges, encompassing environmental, social, cultural, and economic dimensions of sustainability. This study investigates risk mitigation strategies for a heritage-listed, 120-year-old [...] Read more.
Bridges are fundamental components of transportation infrastructure, facilitating the efficient movement of people and goods. However, the conservation of heritage bridges introduces additional challenges, encompassing environmental, social, cultural, and economic dimensions of sustainability. This study investigates risk mitigation strategies for a heritage-listed, 120-year-old reinforced concrete bridge in Australia—one of the nation’s earliest examples of reinforced concrete construction, which remains operational today. The structure faces multiple risks, including passage of overweight vehicles, environmental degradation, progressive crack development due to traffic loading, and potential foundation scouring from an adjacent stream. Due to the heritage status and associated legal constraints, only non-invasive testing methods were employed. Ambient vibration testing was conducted to identify the bridge’s dynamic characteristics under normal traffic conditions, complemented by non-contact displacement monitoring using laser distance sensors. A digital twin structural model was subsequently developed and validated against field data. This model enabled the execution of various “what-if” simulations, including passage of overweight vehicles and loss of foundation due to scouring, providing quantitative assessments of potential risk scenarios. Drawing on insights gained from the case study, the article proposes a six-phase Incident Response Framework tailored for heritage bridge management. This comprehensive framework incorporates remote sensing technologies for incident detection, digital twin-based structural assessment, damage containment and mitigation protocols, recovery planning, and documentation to prevent recurrence—thus supporting the long-term preservation and functionality of heritage bridge assets. Full article
(This article belongs to the Special Issue Feature Papers in Physical Sensors 2025)
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28 pages, 22813 KiB  
Article
Implementation of a BIM-Based Collaboration System for Structural Damage Condition Assessment in an Asymmetric Butterfly Arch Bridge
by Hongxi Qin, Xuan Liu, Changjun Deng, Yang Chen, Chunrong Zou, Anqing Hu and Ao Tang
Buildings 2025, 15(8), 1211; https://doi.org/10.3390/buildings15081211 - 8 Apr 2025
Viewed by 680
Abstract
The developments in building information modeling (BIM) technology provide a new approach for remote real-time visualized bridge health monitoring and structural damage detection, but so far, there are scarcely any application cases of a BIM-based SHM system for butterfly arch bridges around the [...] Read more.
The developments in building information modeling (BIM) technology provide a new approach for remote real-time visualized bridge health monitoring and structural damage detection, but so far, there are scarcely any application cases of a BIM-based SHM system for butterfly arch bridges around the world. This paper reviewed the recent progress on the butterfly arch bridge and its requirements for the integration between SHM and BIM. Based on an actual project in southwest China, work on the spatial mechanical properties, the analysis of monitoring requirements, and the design of functional modules of SHM are elaborately conducted. Subsequently, the lightweight BIM is established and integrated into the web client-side of the SHM system with the skeleton-template method, CATIA platform, and sensor data. With the implementation of user-defined virtual sensor parameter linkage, the design of the specific databases is accomplished in the SQL server environment. Based on one actual incident that saw an overweight/oversize vehicle (with the weight of 80 t, 2015) pass over the arch bridge, the fuzzy relation synthesis and data cleaning method were improved to compare the standard deviation with the threshold value of the correlation degree, and a method is adopted to evaluate the structural operation behavior of the bridge and the service condition of the BIM-based SHM system after the ultra-limit accident. The study results evince the validity and efficiency of the BIM-based SHM system, which could lay a foundation for the visualized assessment and early warning system of long-span bridges. Full article
(This article belongs to the Special Issue Structural Safety Evaluation and Health Monitoring)
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20 pages, 7151 KiB  
Article
Computer Vision-Based Real-Time Identification of Vehicle Loads for Structural Health Monitoring of Bridges
by Jiaxin Yang, Yan Bao, Zhe Sun and Xiaolin Meng
Sustainability 2024, 16(3), 1081; https://doi.org/10.3390/su16031081 - 26 Jan 2024
Cited by 9 | Viewed by 2733
Abstract
Coupling effects of various loading conditions can cause deflections, settlements and even failure of in-service bridges. Although it is one of the most critical loads, unfortunately, loading conditions of moving vehicles are difficult to capture in real time by bridge monitoring systems currently [...] Read more.
Coupling effects of various loading conditions can cause deflections, settlements and even failure of in-service bridges. Although it is one of the most critical loads, unfortunately, loading conditions of moving vehicles are difficult to capture in real time by bridge monitoring systems currently in place for sustainable operation. To fully understand the status of a bridge, it is essential to obtain instantaneous vehicle load distributions in a dynamic traffic environment. Although there are some methods that can identify overweight vehicles, the captured vehicle-related information is scattered and incomplete and thus cannot support effective bridge structural health monitoring (BSHM). This study proposes a noncontact, vision-based approach to identification of vehicle loads for real-time monitoring of bridge structural health. The proposed method consists of four major steps: (1) establish a dual-object detection model for vehicles using YOLOv7, (2) develop a hybrid coordinate transformation model on a bridge desk, (3) develop a multiobject tracking model for real-time trajectory monitoring of moving vehicles, and (4) establish a decision-level fusion model for fusing data on vehicle loads and positions. The proposed method effectively visualizes the 3D spatiotemporal vehicular-load distribution with low delay at a speed of over 30FPS. The results show that the hybrid coordinate transformation ensures that the vehicle position error is within 1 m, a 5-fold reduction compared with the traditional method. Wheelbase is calculated through dual-object detection and transformation and is as the primary reference for vehicle position correction. The trajectory and real-time speed of vehicles are preserved, and the smoothed speed error is under 5.7%, compared with the speed measured by sensors. The authors envision that the proposed method could constitute a new approach for conducting real-time SHM of in-service bridges. Full article
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4 pages, 2117 KiB  
Proceeding Paper
Evaluating Remediation Techniques for Fouled Ballast on Army Installations
by Charles E. Williams and Thomas J. Beasley
Eng. Proc. 2023, 36(1), 26; https://doi.org/10.3390/engproc2023036026 - 7 Jul 2023
Viewed by 890
Abstract
Rail transport is a vital asset for U.S. Army distribution networks for movements of oversized and overweight vehicles and munitions. As the rail infrastructure ages on military installations, the reliability of these rail systems is a critical concern to support military power projection [...] Read more.
Rail transport is a vital asset for U.S. Army distribution networks for movements of oversized and overweight vehicles and munitions. As the rail infrastructure ages on military installations, the reliability of these rail systems is a critical concern to support military power projection requirements. The Engineering Research and Development Center (ERDC) evaluates over 1500 miles of Army track approximately every four years. Many Army installations have significant problems with fouled ballast. These installations have few resources to remediate fouled ballast, and/or may not be aware of remediation techniques. The primary objective of this paper is to provide a list of remediation techniques for installations to implement with efforts to reduce fouled ballast and improve track maintenance. Full article
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19 pages, 7598 KiB  
Article
Load Estimation of Moving Passenger Cars Using Inductive-Loop Technology
by Zbigniew Marszalek, Krzysztof Duda, Piotr Piwowar, Marek Stencel, Tadeusz Zeglen and Jacek Izydorczyk
Sensors 2023, 23(4), 2063; https://doi.org/10.3390/s23042063 - 12 Feb 2023
Cited by 8 | Viewed by 2559
Abstract
Due to their lack of driving controllability, overweight vehicles are a big threat to road safety. The proposed method for a moving passenger car load estimation is capable of detecting an overweight vehicle, and thus it finds its application in road safety improvement. [...] Read more.
Due to their lack of driving controllability, overweight vehicles are a big threat to road safety. The proposed method for a moving passenger car load estimation is capable of detecting an overweight vehicle, and thus it finds its application in road safety improvement. The weight of a car’s load entering or leaving a considered zone, e.g., industrial facility, a state, etc., is also of concern in many applications, e.g., surveillance. Dedicated vehicle weight-in-motion measurement systems generally use expensive load sensors that also require deep intervention in the road while being installed and also are calibrated only for heavy trucks. In this paper, a vehicle magnetic profile (VMP) is used for defining a load parameter proportional to the passenger vehicle load. The usefulness of the proposed load parameter is experimentally demonstrated in field tests. The sensitivity of the VMP to the load change results from the fact that the higher load decreases the vehicle clearance value which in turn increases the VMP. It is also shown that a slim inductive-loop sensors allows the building of a load estimation system, with a maximum error around 30 kg, which allows approximate determination of the number of passengers in the car. The presented proof of concept extends the functionality of inductive loops, already installed in the road, for acquiring other traffic parameters, e.g., moving vehicle axle-to-axle distance measurement, to road safety and surveillance related applications. Full article
(This article belongs to the Collection Sensors and Actuators for Intelligent Vehicles)
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12 pages, 374 KiB  
Review
Unravelling the Complexity of Irregular Shiftwork, Fatigue and Sleep Health for Commercial Drivers and the Associated Implications for Roadway Safety
by Jessica Erin Mabry, Matthew Camden, Andrew Miller, Abhijit Sarkar, Aditi Manke, Christiana Ridgeway, Hardianto Iridiastadi, Tarah Crowder, Mouyid Islam, Susan Soccolich and Richard J. Hanowski
Int. J. Environ. Res. Public Health 2022, 19(22), 14780; https://doi.org/10.3390/ijerph192214780 - 10 Nov 2022
Cited by 18 | Viewed by 3487
Abstract
Fatigue can be a significant problem for commercial motor vehicle (CMV) drivers. The lifestyle of a long-haul CMV driver may include long and irregular work hours, inconsistent sleep schedules, poor eating and exercise habits, and mental and physical stress, all contributors to fatigue. [...] Read more.
Fatigue can be a significant problem for commercial motor vehicle (CMV) drivers. The lifestyle of a long-haul CMV driver may include long and irregular work hours, inconsistent sleep schedules, poor eating and exercise habits, and mental and physical stress, all contributors to fatigue. Shiftwork is associated with lacking, restricted, and poor-quality sleep and variations in circadian rhythms, all shown to negatively affect driving performance through impaired in judgment and coordination, longer reaction times, and cognitive impairment. Overweight and obesity may be as high as 90% in CMV drivers, and are associated with prevalent comorbidities, including obstructive sleep apnea, hypertension, and cardiovascular and metabolic disorders. As cognitive and motor processing declines with fatigue, driver performance decreases, and the risk of errors, near crashes, and crashes increases. Tools and assessments to determine and quantify the nature, severity, and impact of fatigue and sleep disorders across a variety of environments and populations have been developed and should be critically examined before being employed with CMV drivers. Strategies to mitigate fatigue in CMV operations include addressing the numerous personal, health, and work factors contributing to fatigue and sleepiness. Further research is needed across these areas to better understand implications for roadway safety. Full article
18 pages, 2153 KiB  
Article
A Thai Traditional Triple-Fruit Formulation “Phikud Tri-Phon” May Provide Fat Loss and Nutritional Benefits
by Ngamrayu Ngamdokmai, Kornkanok Ingkaninan, C. Norman Scholfield, Kamonlak Insumrong, Nitra Neungchamnong, Genet Minale and Sakan Warinhomhoun
Foods 2022, 11(19), 3067; https://doi.org/10.3390/foods11193067 - 2 Oct 2022
Cited by 3 | Viewed by 4895
Abstract
Obesity and overweight have serious health outcomes. “Phikud Tri-Phon” (PTP) is a traditional Thai medicine comprising three dried fruits from Aegle marmelos L., Morinda citrifolia L., and Coriandrum sativum L. Whether this medicine impacts on metabolic disease is unclear. This study aimed to [...] Read more.
Obesity and overweight have serious health outcomes. “Phikud Tri-Phon” (PTP) is a traditional Thai medicine comprising three dried fruits from Aegle marmelos L., Morinda citrifolia L., and Coriandrum sativum L. Whether this medicine impacts on metabolic disease is unclear. This study aimed to investigate the phenolic and flavonoid contents of PTP and each of its herbal components, and further assess their antioxidant and anti-adipogenetic activities. Oil-red O staining was measured for lipid accumulation in 3T3-L1 adipocytes. The chemical profiles of PTP and each herbal extract were determined by LC-ESI-QTOF-MS/MS. Our results show that the total phenolic and flavonoid contents of PTP water extract were 22.35–108.42 mg of gallic acid equivalents and PTP ethanolic extract was 1.19–0.93 mg of quercetin equivalents and the DPPH scavenging capacity assay of PTP ethanolic extract (1 mg/mL) was 92.45 ± 6.58 (Trolox equivalent)/g. The PTP extracts and individual herbs had inhibitory adipogenesis activity, which reduced lipid accumulation by approximately 31% in PTP water extract and 22% in PTP ethanolic extract compared with control cells. These results provided insights into the traditional preparation method of using boiling water as a vehicle for PTP. In conclusion, PTP has antioxidant and anti-adipogenesis potential, indicating it is a promising ingredient in functional food and herbal health products. Full article
(This article belongs to the Special Issue Bioactive Compounds, Antioxidants, and Health Benefits)
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22 pages, 3314 KiB  
Article
Survival Analysis for Asphalt Pavement Performance and Assessment of Various Factors Affecting Fatigue Cracking Based on LTPP Data
by Ali A. Hatoum, Jamal M. Khatib, Firas Barraj and Adel Elkordi
Sustainability 2022, 14(19), 12408; https://doi.org/10.3390/su141912408 - 29 Sep 2022
Cited by 18 | Viewed by 3944
Abstract
Pavement performance is the ability of pavement to remain in an acceptable condition to serve the intended users over a period of time. There are several principal, combined factors that affect flexible pavement performance such as environmental conditions, pavement materials, and traffic loads. [...] Read more.
Pavement performance is the ability of pavement to remain in an acceptable condition to serve the intended users over a period of time. There are several principal, combined factors that affect flexible pavement performance such as environmental conditions, pavement materials, and traffic loads. Vehicle overloading is considered one of the most significant causes of accelerating flexible pavement deterioration, reducing the pavement’s design life, and affecting the overall sustainability of the pavement system. Therefore, researchers are continuously examining pavement systems with a view to finding the most suitable solutions for sustainable development in road construction systems in order to reduce both costs and pollution. In this study, we present a framework to conduct nonparametric and parametric survival analysis for asphalt pavement test sections, to assess the influence of using reclaimed asphalt pavement (RAP) on fatigue service life, to indicate the most significant subset of risk factors (covariates), and to study the effect of overweight axles on flexible pavement performance. All the data concerned were extracted from the long-term pavement performance (LTPP) program. The Kaplan–Meier (KM) survival probability curves of multiple pavement distresses were developed to compare the failure probability for various distresses and to determine the median survival time for each distress. The fatigue survival curves for the test sections using RAP and virgin materials were developed separately and the equality of the two survival curves was tested and affirmed. Several parametric survival analyses were conducted to select the most significant subset of covariates. For fatigue cracking and, after dropping the insignificant predictors, a model was developed to show the quantitative relationship between fatigue failure time and potentially influential factors. The analysis indicated that the increase in the percentage of overloaded axles from 0% to 20% can reduce the fatigue survival life of flexible pavement by up to 55%. In the absence of overweight axles, a one-inch increase in asphalt layer thickness can extend the fatigue service life by about half a year. However, in the presence of 20% of overweight axles, a one-inch increase in thickness can extend the fatigue service life by only 0.22 years. Therefore, additional virgin materials and resources are needed to maintain traffic conditions in the road network and to compensate for the reduction in fatigue service life. Moreover, the effect of the increase in overweight axles from 0% to 15% on reducing the fatigue survival life is found to be similar to the effect of increasing the AADTT tenfold. Therefore, the sustainability of pavement is directly affected by the fatigue survival life. Full article
(This article belongs to the Special Issue Green Infrastructure and Recycled Materials Sustainability)
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10 pages, 562 KiB  
Article
Assessing Factors Associated with Non-Fatal Injuries from Road Traffic Accidents among Malaysian Adults: A Cross-Sectional Analysis of the PURE Malaysia Study
by Zaleha Md Isa, Noor Hassim Ismail, Rosnah Ismail, Azmi Mohd Tamil, Mohd Hasni Ja’afar, Nafiza Mat Nasir, Maizatullifah Miskan, Najihah Zainol Abidin, Nurul Hafiza Ab Razak and Khairul Hazdi Yusof
Int. J. Environ. Res. Public Health 2022, 19(14), 8246; https://doi.org/10.3390/ijerph19148246 - 6 Jul 2022
Cited by 2 | Viewed by 2709
Abstract
Non-fatal injuries (NFIs) due to road traffic accidents (RTAs) are a public health problem worldwide that significantly impacts the population morbidity and healthcare costs. As the demands for vehicles in developing countries, such as Malaysia, is increasing annually, the present study aims to [...] Read more.
Non-fatal injuries (NFIs) due to road traffic accidents (RTAs) are a public health problem worldwide that significantly impacts the population morbidity and healthcare costs. As the demands for vehicles in developing countries, such as Malaysia, is increasing annually, the present study aims to determine the prevalence and factors associated with NFIs due to RTAs among Malaysia’s adult population. Methods: This was a cross-sectional study involving 15,321 participants from the Prospective Urban and Rural Epidemiological (PURE) study conducted in Malaysia. Participants reported whether they had experienced an NFI that limited their normal activities within the past 12 months. Data on risk factors for NFIs were elicited. Multiple logistic regression models were fitted to identify the associated factors. Results: Overall, 863 participants (5.6% of 15,321) reported at least 1 NFI in the past 12 months, with 303 caused by RTAs (35.1%), 270 caused by falls (31.3%) and 290 attributed to other causes (33.6%). The factors associated with higher odds of sustaining an NFI due to an RTA were being male (adjusted odd ratio (AOR) 2.08; 95% CI 1.33–3.26), having a primary (2.52; 1.40–4.55) or secondary (2.64; 1.55–4.49) level of education, being overweight to obese (1.40; 1.01–1.94), being currently employed (2.03; 1.31–3.13) and not practicing a noon nap/siesta (1.38; 1.01–1.89). Conclusions: The occurrence of NFIs due to RTAs is highly preventable with strategic planning aimed at reducing the risk of RTAs among the Malaysian population. Interventions focusing on protecting road users, especially those who drive two-wheelers, with proactive road safety awareness and literacy campaigns, combined with strict enforcement of the existing traffic laws and behavioural modifications, may reduce the risk of NFIs following RTAs. Full article
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22 pages, 17745 KiB  
Article
Mechanistic–Empirical Analysis of Pavement Performance Considering Dynamic Axle Load Spectra Due to Longitudinal Unevenness
by Jingnan Zhao, Hao Wang, Pan Lu and Jiaqi Chen
Appl. Sci. 2022, 12(5), 2600; https://doi.org/10.3390/app12052600 - 2 Mar 2022
Cited by 6 | Viewed by 4426
Abstract
Pavement distresses are induced by mechanistic responses in pavement structure subjected to dynamic loads of moving vehicles. Pavement surface evenness deteriorates as pavement distresses propagate, which results in dynamic axle loads and faster pavement deterioration. It is vital to consider the dynamic axle [...] Read more.
Pavement distresses are induced by mechanistic responses in pavement structure subjected to dynamic loads of moving vehicles. Pavement surface evenness deteriorates as pavement distresses propagate, which results in dynamic axle loads and faster pavement deterioration. It is vital to consider the dynamic axle load spectra to predict pavement deterioration using traffic-monitoring data. This study aimed to evaluate the effect of dynamic loads and overweight traffic on asphalt pavement overlay performance using mechanistic–empirical (M–E) pavement analysis. The relationship between dynamic load coefficients (DLCs), axle loads, and international roughness index (IRI) was obtained for accurate quantification of dynamic axle loads. Then the dynamic axle load spectra were derived by shifting the static axle load spectra in weigh-in-motion (WIM) data, given the DLC value. AASHTOWare Pavement ME software was used to analyze pavement performance with static and dynamic axle load spectra, and the impact of overweight traffic on asphalt pavement overlay performance. The impact of dynamic loads on reflective fatigue cracking was distinguished at an early stage of the service period and eliminated after the 10-year analysis period, when the propagation of reflective cracking reached a specific level. On the other hand, the consideration of dynamic axle loads increased the impact of overweight truck traffic on pavement distresses, and pavement structures of major highways tend to be more sensitive to overweight traffic because of greater DLC excitement at higher operational speeds. Full article
(This article belongs to the Special Issue Road Materials and Sustainable Pavement Design)
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15 pages, 340 KiB  
Article
Adherence to the Mediterranean Diet Is Associated with Better Metabolic Features in Youths with Type 1 Diabetes
by Valentina Antoniotti, Daniele Spadaccini, Roberta Ricotti, Deborah Carrera, Silvia Savastio, Filipa Patricia Goncalves Correia, Marina Caputo, Erica Pozzi, Simonetta Bellone, Ivana Rabbone and Flavia Prodam
Nutrients 2022, 14(3), 596; https://doi.org/10.3390/nu14030596 - 29 Jan 2022
Cited by 26 | Viewed by 4168
Abstract
Our aim was to evaluate adherence to the Mediterranean diet (MedDiet) among children and adolescents with type 1 diabetes (T1D) in relation to metabolic control. Adherence to the MedDiet was assessed with the Mediterranean Diet Quality Index (KIDMED) questionnaire and physical activity by [...] Read more.
Our aim was to evaluate adherence to the Mediterranean diet (MedDiet) among children and adolescents with type 1 diabetes (T1D) in relation to metabolic control. Adherence to the MedDiet was assessed with the Mediterranean Diet Quality Index (KIDMED) questionnaire and physical activity by the International Physical Activity Questionnaire for Adolescent (IPAQ-A) on 65 subjects (32 males, 9–18 years) with T1D. Clinical and metabolic evaluation was performed (standardized body mass index (BMI-SDS), hemoglobin A1C (HbA1c), continuous glucose monitoring metrics when present, blood pressure, lipid profile). Parental characteristics (age, body mass index (BMI), socio-economic status) were reported. The adherence to the MedDiet was poor in 12.3%, average in 58.6%, and high in 29.1% of the subjects. Furthermore, 23.4% of patients were overweight/obese. The most impacting factors on BMI-SDS were skipping breakfast and their father’s BMI. HbA1c and time in range % were positively associated with sweets and fish intake, respectively. Additionally, the father’s socio-economic status (SES) and mother’s age were associated with glucose control. Blood pressure was associated with travelling to school in vehicles, extra-virgin olive oil intake and milk/dairy consumption at breakfast. The promotion of the MedDiet, mainly having a healthy breakfast, is a good strategy to include in the management of T1D to improve glucose and metabolic control. This research is valuable for parents to obtain the best results for their children with T1D. Full article
19 pages, 2789 KiB  
Article
Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue
by Wiem Haj Ahmed, Cécile Peiro, Jessica Fontaine, Barry J. Ryan, Gemma K. Kinsella, Jeff O’Sullivan, Jean-Louis Grolleau, Gary T.M. Henehan and Christian Carpéné
Medicines 2020, 7(4), 18; https://doi.org/10.3390/medicines7040018 - 2 Apr 2020
Cited by 5 | Viewed by 4684
Abstract
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase. To the best of our knowledge, no direct demonstration of any interplay between these phytochemicals and human primary amine oxidase (PrAO) has [...] Read more.
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase. To the best of our knowledge, no direct demonstration of any interplay between these phytochemicals and human primary amine oxidase (PrAO) has been reported to date. We took advantage of the coexistence of PrAO and monoamine oxidase (MAO) activities in human subcutaneous adipose tissue (hScAT) to test the interaction between several methylxanthines and these enzymes, which are involved in many key pathophysiological processes. Methods: Benzylamine, methylamine, and tyramine were used as substrates for PrAO and MAO in homogenates of subcutaneous adipose depots obtained from overweight women undergoing plastic surgery. Methylxanthines were tested as substrates or inhibitors by fluorimetric determination of hydrogen peroxide, an end-product of amine oxidation. Results: Semicarbazide-sensitive PrAO activity was inhibited by theobromine, caffeine, and isobutylmethylxanthine (IBMX) while theophylline, paraxanthine, and 7-methylxanthine had little effect. Theobromine inhibited PrAO activity by 54% at 2.5 mM. Overall, the relationship between methylxanthine structure and the degree of inhibition was similar to that seen with bovine PrAO, although higher concentrations (mM) were required for inhibition. Theobromine also inhibited oxidation of tyramine by MAO, at the limits of its solubility in a DMSO vehicle. At doses higher than 12 % v/v, DMSO impaired MAO activity. MAO was also inhibited by millimolar doses of IBMX, caffeine and by other methylxanthines to a lesser extent. Conclusions: This preclinical study extrapolates previous findings with bovine PrAO to human tissues. Given that PrAO is a potential target for anti-inflammatory drugs, it indicates that alongside phosphodiesterase inhibition and adenosine receptor antagonism, PrAO and MAO inhibition could contribute to the health benefits of methylxanthines, especially their anti-inflammatory effects. Full article
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17 pages, 2557 KiB  
Article
Investigation of Weigh-in-Motion Measurement Accuracy on the Basis of Steering Axle Load Spectra
by Dawid Rys
Sensors 2019, 19(15), 3272; https://doi.org/10.3390/s19153272 - 25 Jul 2019
Cited by 30 | Viewed by 5719
Abstract
Weigh-in-motion systems are installed in pavements or on bridges to identify and reduce the number of overloaded vehicles and minimise their adverse effect on road infrastructure. Moreover, the collected traffic data are used to obtain axle load characteristics, which are very useful in [...] Read more.
Weigh-in-motion systems are installed in pavements or on bridges to identify and reduce the number of overloaded vehicles and minimise their adverse effect on road infrastructure. Moreover, the collected traffic data are used to obtain axle load characteristics, which are very useful in road infrastructure design. Practical application of data from weigh-in-motion has become more common recently, which calls for adequate attention to data quality. This issue is addressed in the presented paper. The aim of the article is to investigate the accuracy of 77 operative weigh-in-motion stations by analysing steering axle load spectra. The proposed methodology and analysis enabled the identification of scale and source of errors that occur in measurements delivered from weigh-in-motion systems. For this purpose, selected factors were investigated, including the type of axle load sensor, air temperature and vehicle speed. The results of the analysis indicated the obvious effect of the axle load sensor type on the measurement results. It was noted that systematic error increases during winter, causing underestimation of axle loads by 5% to 10% for quartz piezoelectric and bending beam load sensors, respectively. A deterioration of system accuracy is also visible when vehicle speed decreases to 30 km/h. For 25% to 35% of cases, depending on the type of sensor, random error increases for lower speeds, while it remains at a constant level at higher speeds. The analysis also delivered a standard steering axle load distribution, which can have practical meaning in the improvement of weigh-in-motion accuracy and traffic data quality. Full article
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35 pages, 3949 KiB  
Article
Evaluating Impacts of Overweight in Road Freight Transportation: A Case Study in Brazil with System Dynamics
by Verônica Ghisolfi, Glaydston Mattos Ribeiro, Gisele de Lorena Diniz Chaves, Rômulo Dante Orrico Filho, Ivone Catarina Simões Hoffmann and Leonardo Roberto Perim
Sustainability 2019, 11(11), 3128; https://doi.org/10.3390/su11113128 - 3 Jun 2019
Cited by 24 | Viewed by 18488
Abstract
Overweight vehicles in ornamental stone transportation reduce the lifespan of the pavement and increase accidents on Brazilian highways. This paper evaluates the relationship between different policies for the loading of ornamental stone vehicles and its externalities, such as the impact on costs with [...] Read more.
Overweight vehicles in ornamental stone transportation reduce the lifespan of the pavement and increase accidents on Brazilian highways. This paper evaluates the relationship between different policies for the loading of ornamental stone vehicles and its externalities, such as the impact on costs with transportation, pavement maintenance and road accidents, using the System Dynamics (SD) method. The results confirm the advantages of reducing operational costs with the practice of overweight. However, as the overweight increases, the pavement maintenance and road accidents costs also increase. Therefore, the best vehicle loading policy depends on the relative importance of the economic and social costs involved. Full article
(This article belongs to the Section Sustainable Transportation)
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20 pages, 4248 KiB  
Article
Interactive Data Framework and User Interface for Wisconsin’s Oversize-Overweight Vehicle Permits
by Ahmed S. Shatnawi, Nicholas Coley and Hani H. Titi
Data 2018, 3(2), 20; https://doi.org/10.3390/data3020020 - 15 Jun 2018
Cited by 2 | Viewed by 4478
Abstract
With continuing increases in the number of Oversize-Overweight (OSOW) vehicle permits issued in recent years, the management and analysis of OSOW permit data is becoming more inefficient and time-consuming. Large quantities of archived OSOW permit data are held by Departments of Transportation (DOTs) [...] Read more.
With continuing increases in the number of Oversize-Overweight (OSOW) vehicle permits issued in recent years, the management and analysis of OSOW permit data is becoming more inefficient and time-consuming. Large quantities of archived OSOW permit data are held by Departments of Transportation (DOTs) across the United States, and manual extraction and analysis of this data requires significant effort. In this paper, the authors present a new framework for analyzing Wisconsin’s historic OSOW permit program data. This framework provides an interactive, web-based interface to query the OSOW permit data, link OSOW records to geospatial data features, and dynamically visualize query results. The web-based interface offers scalability and broad accessibility to the data across different DOT divisions, and use cases. Furthermore, a user survey and heuristic evaluation of the interface demonstrate the project’s utility, and identify goals for future system development. Full article
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