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17 pages, 1097 KiB  
Review
Natural Feed Additives in Sub-Saharan Africa: A Systematic Review of Efficiency and Sustainability in Ruminant Production
by Zonaxolo Ntsongota, Olusegun Oyebade Ikusika and Thando Conference Mpendulo
Ruminants 2025, 5(3), 36; https://doi.org/10.3390/ruminants5030036 - 6 Aug 2025
Abstract
Ruminant livestock production plays a crucial role in the agricultural systems of Sub-Saharan Africa, significantly supporting rural livelihoods through income generation, improved nutrition, and employment opportunities. Despite its importance, the sector continues to face substantial challenges, such as low feed quality, seasonal feed [...] Read more.
Ruminant livestock production plays a crucial role in the agricultural systems of Sub-Saharan Africa, significantly supporting rural livelihoods through income generation, improved nutrition, and employment opportunities. Despite its importance, the sector continues to face substantial challenges, such as low feed quality, seasonal feed shortages, and climate-related stresses, all of which limit productivity and sustainability. Considering these challenges, the adoption of natural feed additives has emerged as a promising strategy to enhance animal performance, optimise nutrient utilisation, and mitigate environmental impacts, including the reduction of enteric methane emissions. This review underscores the significant potential of natural feed additives such as plant extracts, essential oils, probiotics, and mineral-based supplements such as fossil shell flour as sustainable alternatives to conventional growth promoters in ruminant production systems across the region. All available documented evidence on the topic from 2000 to 2024 was collated and synthesised through standardised methods of systematic review protocol—PRISMA. Out of 319 research papers downloaded, six were included and analysed directly or indirectly in this study. The results show that the addition of feed additives to ruminant diets in all the studies reviewed significantly (p < 0.05) improved growth parameters such as average daily growth (ADG), feed intake, and feed conversion ratio (FCR) compared to the control group. However, no significant (p > 0.05) effect was found on cold carcass weight (CCW), meat percentage, fat percentage, bone percentage, or intramuscular fat (IMF%) compared to the control. The available evidence indicates that these additives can provide tangible benefits, including improved growth performance, better feed efficiency, enhanced immune responses, and superior meat quality, while also supporting environmental sustainability by reducing nitrogen excretion and decreasing dependence on antimicrobial agents. Full article
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19 pages, 1584 KiB  
Article
The Development of a Predictive Maintenance System for Gearboxes Through a Statistical Diagnostic Analysis of Lubricating Oil and Artificial Intelligence
by Diego Rigolli, Lorenzo Pompei, Massimo Manfredini, Massimiliano Vignoli, Vincenzo La Battaglia and Alessandro Giorgetti
Machines 2025, 13(8), 693; https://doi.org/10.3390/machines13080693 - 6 Aug 2025
Abstract
This paper addressed the problem of oil diagnostics lubricants applied to the predictive maintenance of industrial gearboxes, proposing the integration of an artificial intelligence (AI) system into the process analysis. The main objective was to overcome the critical issues of the traditional method, [...] Read more.
This paper addressed the problem of oil diagnostics lubricants applied to the predictive maintenance of industrial gearboxes, proposing the integration of an artificial intelligence (AI) system into the process analysis. The main objective was to overcome the critical issues of the traditional method, characterized by long analysis times and a marked dependence on the subjective interpretation of operators. The method includes a detailed statistical analysis of the common ways to assess the condition of lubricants, such as optical emission spectroscopy, particle counting, measuring viscosity and density, and Fourier-transform infrared spectroscopy (FT-IR). These methods are then combined with an artificial intelligence model. Tested on commercial gearbox data, the proposed approach demonstrates agreement between IA and expert evaluation. The application has shown that it can effectively support diagnoses, reduce processing time by 60%, and minimize human errors. It also improves knowledge sharing through an increase in the stability and repetitiveness of diagnoses and promotes consistency and clarity in reporting. Full article
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19 pages, 1899 KiB  
Article
Performance Analysis of New Deuterium Tracer for Online Oil Consumption Measurements
by Francesco Marzemin, Martin Vareka, Kevin Gschiel, Bernhard Rossegger, Peter Grabner, Michael Engelmayer and Nicole Wermuth
Lubricants 2025, 13(8), 351; https://doi.org/10.3390/lubricants13080351 - 5 Aug 2025
Abstract
The accurate and precise measurement of lubricating oil consumption is critical for developing environmentally friendly internal combustion engines, particularly hydrogen-fueled internal combustion engines. The deuterium tracer method is based on the addition of poly-deuterated base oil tracers to fully formulated oils for precise, [...] Read more.
The accurate and precise measurement of lubricating oil consumption is critical for developing environmentally friendly internal combustion engines, particularly hydrogen-fueled internal combustion engines. The deuterium tracer method is based on the addition of poly-deuterated base oil tracers to fully formulated oils for precise, accurate, and fast lubricating oil consumption measurements. Previously performed measurements have shown that the use of poly-deuterated poly-alpha olefins has minimal impact on lubricating oil properties, except for a slight drop in oil viscosity. To further reduce the impact on lubricating oil characteristics, a new base oil for the synthesis of a poly-deuterated tracer is introduced, and its influence on the lubricating oil’s chemical, tribological, and rheological properties is analyzed. Furthermore, the influence of the tracer addition on the preignition tendencies of the fully formulated oil is also examined. Based on the analyses, no relevant changes in the lubricating oil properties, such as viscosity, density, and thermal degradation behavior, can be observed. Additionally, the deuterium tracer does not negatively influence combustion anomalies, thus reducing preignition tendencies. These results establish the method’s compatibility with new-generation engines, especially hydrogen-fueled internal combustion engines. Full article
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18 pages, 1471 KiB  
Article
Microclimate Modification, Evapotranspiration, Growth and Essential Oil Yield of Six Medicinal Plants Cultivated Beneath a Dynamic Agrivoltaic System in Southern Italy
by Grazia Disciglio, Antonio Stasi, Annalisa Tarantino and Laura Frabboni
Plants 2025, 14(15), 2428; https://doi.org/10.3390/plants14152428 - 5 Aug 2025
Abstract
This study, conducted in Southern Italy in 2023, investigated the effects of a dynamic agrivoltaics (AV) system on microclimate, water consumption, plant growth, and essential oil yield in six medicinal species: lavender (Lavandula angustifolia L. ‘Royal purple’), lemmon thyme (Thymus citriodorus [...] Read more.
This study, conducted in Southern Italy in 2023, investigated the effects of a dynamic agrivoltaics (AV) system on microclimate, water consumption, plant growth, and essential oil yield in six medicinal species: lavender (Lavandula angustifolia L. ‘Royal purple’), lemmon thyme (Thymus citriodorus (Pers.) Schreb. ar. ‘Aureus’), common thyme (Thymus vulgaris L.), rosemary (Salvia rosmarinus Spenn. ‘Severn seas’), mint (Mentha spicata L. ‘Moroccan’), and sage (Salvia officinalis L. subsp. Officinalis). Due to the rotating solar panels, two distinct ground zones were identified: a consistently shaded area under the panels (UP), and a partially shaded area between the panels (BP). These were compared to an adjacent full-sun control area (T). Microclimate parameters, including solar radiation, air and leaf infrared temperature, and soil temperature, were recorded throughout the cultivation season. Reference evapotranspiration (ETO) was calculated using Turc’s method, and crop evapotranspiration (ETC) was estimated with species-specific crop coefficients (KC). Results showed significantly lower microclimatic values in the UP plot compared to both BP and especially T, resulting in ETC reductions of 81.1% in UP and 13.1% in BP relative to T, an advantage in water-scarce environments. Growth and yield responses varied among species and treatment plots. Except for mint, all species showed a significant reduction in fresh biomass (40.1% to 48.8%) under the high shading of UP compared to T. However, no biomass reductions were observed in BP. Notably, essential oil yields were higher in both UP and BP plots (0.60–2.63%) compared to the T plot (0.51–1.90%). These findings demonstrate that dynamic AV systems can enhance water use efficiency and essential oil yield, offering promising opportunities for sustainable, high-quality medicinal crop production in arid and semi-arid regions. Full article
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15 pages, 920 KiB  
Article
Toxicity and Detoxification Enzyme Inhibition in the Two-Spotted Spider Mite (Tetranychus urticae Koch) by Artemisia annua L. Essential Oil and Its Major Monoterpenoids
by Fatemeh Nasr Azadani, Jalal Jalali Sendi, Asgar Ebadollahi, Roya Azizi and William N. Setzer
Insects 2025, 16(8), 811; https://doi.org/10.3390/insects16080811 - 5 Aug 2025
Abstract
The two-spotted spider mite, Tetranychus urticae, is one of the polyphagous pests of several crops and forestry, resistant to numerous conventional chemicals. Due to the negative side effects of harmful chemical pesticides, such as environmental pollution, and risks to human health, the [...] Read more.
The two-spotted spider mite, Tetranychus urticae, is one of the polyphagous pests of several crops and forestry, resistant to numerous conventional chemicals. Due to the negative side effects of harmful chemical pesticides, such as environmental pollution, and risks to human health, the introduction of effective and low-risk alternatives is essential. The promising pesticidal effects of essential oils (EOs) isolated from Artemisia annua have been documented in recent studies. In the present study, the acaricidal effects of an A. annua EO, along with its two dominant monoterpenoids, 1,8-cineole and camphor, were investigated against adults of T. urticae. Artemisia annua EO, 1,8-cineole, and camphor, with 24 h-LC50 values of 0.289, 0.533, and 0.64 µL/L air, respectively, had significant toxicity by fumigation against T. urticae adults. Along with lethality, A. annua EO and monoterpenoids had significant inhibitory effects on the activity of detoxifying enzymes, including α- and β-esterases, glutathione S-transferases, and cytochrome P-450 monooxygenase. According to the findings of the present study, A. annua EO and its two dominant monoterpenoids, 1,8-cineole and camphor, with significant toxicity and inhibitory effects on detoxifying enzymes, can be introduced as available, effective, and eco-friendly acaricides in the management of T. urticae. Full article
(This article belongs to the Special Issue Plant Essential Oils for the Control of Insects and Mites)
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23 pages, 3106 KiB  
Article
Preparation of a Nanomaterial–Polymer Dynamic Cross-Linked Gel Composite and Its Application in Drilling Fluids
by Fei Gao, Peng Xu, Hui Zhang, Hao Wang, Xin Zhao, Xinru Li and Jiayi Zhang
Gels 2025, 11(8), 614; https://doi.org/10.3390/gels11080614 - 5 Aug 2025
Abstract
During the process of oil and gas drilling, due to the existence of pores or micro-cracks, drilling fluid is prone to invade the formation. Under the action of hydration expansion of clay in the formation and liquid pressure, wellbore instability occurs. In order [...] Read more.
During the process of oil and gas drilling, due to the existence of pores or micro-cracks, drilling fluid is prone to invade the formation. Under the action of hydration expansion of clay in the formation and liquid pressure, wellbore instability occurs. In order to reduce the wellbore instability caused by drilling fluid intrusion into the formation, this study proposed a method of forming a dynamic hydrogen bond cross-linked network weak gel structure with modified nano-silica and P(AM-AAC). The plugging performance of the drilling fluid and the performance of inhibiting the hydration of shale were evaluated through various experimental methods. The results show that the gel composite system (GCS) effectively optimizes the plugging performance of drilling fluid. The 1% GCS can reduce the linear expansion rate of cuttings to 14.8% and increase the recovery rate of cuttings to 96.7%, and its hydration inhibition effect is better than that of KCl and polyamines. The dynamic cross-linked network structure can significantly increase the viscosity of drilling fluid. Meanwhile, by taking advantage of the liquid-phase viscosity effect and the physical blocking effect, the loss of drilling fluid can be significantly reduced. Mechanism studies conducted using zeta potential measurement, SEM analysis, contact angle measurement and capillary force assessment have shown that modified nano-silica stabilizes the wellbore by physically blocking the nano-pores of shale and changing the wettability of the shale surface from hydrophilic to hydrophobic when the contact angle exceeds 60°, thereby reducing capillary force and surface free energy. Meanwhile, the dynamic cross-linked network can reduce the seepage of free water into the formation, thereby significantly lowering the fluid loss of the drilling fluid. This research provides new insights into improving the stability of the wellbore in drilling fluids. Full article
(This article belongs to the Special Issue Advanced Gels for Oil Recovery (2nd Edition))
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19 pages, 3697 KiB  
Article
Investigating the Behavior of a Natural Emulsifier in One-Pot and Standard Cosmetic Emulsions
by Mauro Battaiotto, Paolo Sonzini, Simone Conti, Miryam Chiara Malacarne and Enrico Caruso
Cosmetics 2025, 12(4), 164; https://doi.org/10.3390/cosmetics12040164 - 5 Aug 2025
Abstract
The cosmetic industry is growing at an impressive rate worldwide. In the cosmetic field, natural-origin ingredients represent the new frontier in this industry. Among the main components of cosmetics, lipids, emulsifiers, rheological modifiers, preservatives, colorants, and antioxidants can be found. These compounds form [...] Read more.
The cosmetic industry is growing at an impressive rate worldwide. In the cosmetic field, natural-origin ingredients represent the new frontier in this industry. Among the main components of cosmetics, lipids, emulsifiers, rheological modifiers, preservatives, colorants, and antioxidants can be found. These compounds form emulsions, which are among the main cosmetic formulations. An important aspect in this regard is the evaluation of emulsions’ stability over time and emulsions’ production methodology. In this paper, a comparison is made between two emulsion production technologies, the Standard and the “One-Pot” methods, through the characterization of the raw material ABWAX® Revomul, a multifunctional wax for cosmetic use which consists of a low-melting structuring wax of vegetal origin (Rhus wax) and a natural emulsifier (Polyglyceril-3 Stearate). First, we evaluated the affinity between the wax raw materials and emollients of different chemical nature; then, we analyzed the impact of the production method on the emulsions to identify similarities and differences. ABWAX® Revomul demonstrated a high level of effectiveness in regard to stabilizing water-in-oil emulsions. This study suggests that from an industrial point of view, the application of the two procedures allows products with different characteristics to be obtained, consequently allowing a specific method to be chosen to obtain the desired product. Full article
(This article belongs to the Special Issue Advanced Cosmetic Sciences: Sustainability in Materials and Processes)
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21 pages, 1245 KiB  
Article
Geochemical Behaviour of Trace Elements in Diesel Oil-Contaminated Soil During Remediation Assisted by Mineral and Organic Sorbents
by Mirosław Wyszkowski and Natalia Kordala
Appl. Sci. 2025, 15(15), 8650; https://doi.org/10.3390/app15158650 (registering DOI) - 5 Aug 2025
Abstract
The topic of environmental pollution by petroleum products is highly relevant due to rapid urbanisation, including industrial development, road infrastructure and fuel distribution. Potential threat areas include refineries, fuel stations, pipelines, warehouses and transshipment bases, as well as sites affected by accidents or [...] Read more.
The topic of environmental pollution by petroleum products is highly relevant due to rapid urbanisation, including industrial development, road infrastructure and fuel distribution. Potential threat areas include refineries, fuel stations, pipelines, warehouses and transshipment bases, as well as sites affected by accidents or fuel spills. This study aimed to determine whether organic and mineral materials could mitigate the effects of diesel oil pollution on the soil’s trace element content. The used materials were compost, bentonite and calcium oxide. Diesel oil pollution had the most pronounced effect on the levels of Cd, Ni, Fe and Co. The levels of the first three elements increased, while the level of Co decreased by 53%. Lower doses of diesel oil (2.5 and 5 cm3 per kg of soil) induced an increase in the levels of the other trace elements, while higher doses caused a reduction, especially in Cr. All materials applied to the soil (compost, bentonite and calcium oxide) reduced the content of Ni, Cr and Fe. Compost and calcium oxide also increased Co accumulation in the soil. Bentonite had the strongest reducing effect on the Ni and Cr contents of the soil, reducing them by 42% and 53%, respectively. Meanwhile, calcium oxide had the strongest reducing effect on Fe and Co accumulation, reducing it by 12% and 31%, respectively. Inverse relationships were recorded for Cd (mainly bentonite), Pb (especially compost), Cu (mainly compost), Mn (mainly bentonite) and Zn (only compost) content in the soil. At the most contaminated site, the application of bentonite reduced the accumulation of Pb, Zn and Mn in the soil, while the application of compost reduced the accumulation of Cd. Applying various materials, particularly bentonite and compost, limits the content of certain trace elements in the soil. This has a positive impact on reducing the effect of minor diesel oil pollution on soil properties and can promote the proper growth of plant biomass. Full article
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16 pages, 3826 KiB  
Article
Surface Resistivity Imaging for Drilling Columnar Cores
by Qi Ran, Qiang Lai, Benjian Zhang, Yuyu Wu, Jun Tang and Zhe Wu
Symmetry 2025, 17(8), 1238; https://doi.org/10.3390/sym17081238 - 5 Aug 2025
Abstract
The resistivity imaging system is specifically designed for the precise measurement of resistivity distributions within drilled columnar core samples. Its coaxial symmetric configuration enables the non-destructive characterization of electrical properties, with broad applications in oil and gas exploration, reservoir evaluation, and geological research. [...] Read more.
The resistivity imaging system is specifically designed for the precise measurement of resistivity distributions within drilled columnar core samples. Its coaxial symmetric configuration enables the non-destructive characterization of electrical properties, with broad applications in oil and gas exploration, reservoir evaluation, and geological research. By integrating a ring return electrode and full-circumference electrode arrays, the system can acquire core-scale resistivity data in conductive media environments. The self-developed imaging software employs advanced processing algorithms—including depth correction, amplitude normalization, and image enhancement—to transform raw resistivity measurements into high-resolution surface imaging maps. Experimental results demonstrate that the system can resolve features such as cracks with a minimum width of 0.5 mm and pores with a minimum inner diameter of 0.4 mm in granite core, providing a novel technical approach for the fine-scale characterization of core materials. Full article
(This article belongs to the Special Issue Symmetry in Civil Transportation Engineering—2nd Edition)
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19 pages, 14190 KiB  
Article
A Comprehensive Evaluation Method for Cement Slurry Systems to Enhance Zonal Isolation: A Case Study in Shale Oil Well Cementing
by Xiaoqing Zheng, Weitao Song, Xiutian Yang, Jian Liu, Tao Jiang, Xuning Wu and Xin Liu
Energies 2025, 18(15), 4138; https://doi.org/10.3390/en18154138 - 4 Aug 2025
Abstract
Due to post-cementing hydraulic fracturing and other operational stresses, inadequate mechanical properties or suboptimal design of the cement sheath can lead to tensile failure and microcrack development, compromising both hydrocarbon recovery and well integrity. In this study, three field-deployed cement slurry systems were [...] Read more.
Due to post-cementing hydraulic fracturing and other operational stresses, inadequate mechanical properties or suboptimal design of the cement sheath can lead to tensile failure and microcrack development, compromising both hydrocarbon recovery and well integrity. In this study, three field-deployed cement slurry systems were compared on the basis of their basic mechanical properties such as compressive and tensile strength. Laboratory-scale physical simulations of hydraulic fracturing during shale oil production were conducted, using dynamic permeability as a quantitative indicator of integrity loss. The experimental results show that evaluating only basic mechanical properties is insufficient for cement slurry system design. A more comprehensive mechanical assessment is re-quired. Incorporation of an expansive agent into the cement slurry system can alleviate the damage caused by the microannulus to the interfacial sealing performance of the cement sheath, while adding a toughening agent can alleviate the damage caused by tensile cracks to the sealing performance of the cement sheath matrix. Through this research, a microexpansive and toughened cement slurry system, modified with both expansive and toughening agents, was optimized. The expansive agent and toughening agent can significantly enhance the shear strength, the flexural strength, and the interfacial hydraulic isolation strength of cement stone. Moreover, the expansion agents mitigate the detrimental effects of microannulus generation on the interfacial sealing, while the toughening agents alleviate the damage caused by tensile cracking to the bulk sealing performance of the cement sheath matrix. This system has been successfully implemented in over 100 wells in the GL block of Daqing Oilfield. Field application results show that the proportion of high-quality well sections in the horizontal section reached 88.63%, indicating the system’s high performance in enhancing zonal isolation and cementing quality. Full article
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20 pages, 346 KiB  
Review
Dietary Strategies in the Prevention of MASLD: A Comprehensive Review of Dietary Patterns Against Fatty Liver
by Barbara Janota, Karolina Janion, Aneta Buzek and Ewa Janczewska
Metabolites 2025, 15(8), 528; https://doi.org/10.3390/metabo15080528 - 4 Aug 2025
Abstract
Understanding the components of the diet, food groups, and nutritional strategies that help prevent MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) is essential for identifying dietary behaviors that can stop the progression of this condition, which currently affects over one-quarter of the global population. [...] Read more.
Understanding the components of the diet, food groups, and nutritional strategies that help prevent MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) is essential for identifying dietary behaviors that can stop the progression of this condition, which currently affects over one-quarter of the global population. This review highlights the importance of including antioxidant nutrients in the diet, such as vitamins C and E, CoQ10, and polyphenolic compounds. It also emphasizes substances that support lipid metabolism, including choline, alpha-lipoic acid, and berberine. Among food groups, it is crucial to choose those that help prevent metabolic disturbances. Among carbohydrate-rich foods, vegetables, fruits, and high-fiber products are recommended. For protein sources, eggs, fish, and white meat are preferred. Among fat sources, plant oils and fatty fish are advised due to their content of omega-3 and omega-6 fatty acids. Various dietary strategies aimed at preventing MASLD should include elements of the Mediterranean diet or be personalized to provide anti-inflammatory compounds and substances that inhibit fat accumulation in liver cells. Other recommended dietary models include the DASH diet, the flexitarian diet, intermittent fasting, and diets that limit fructose and simple sugars. Additionally, supplementing the diet with spirulina or chlorella, berberine, probiotics, or omega-3 fatty acids, as well as drinking several cups of coffee per day, may be beneficial. Full article
(This article belongs to the Special Issue Metabolic Dysregulation in Fatty Liver Disease)
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13 pages, 4747 KiB  
Article
Biodegradable Polyalphaolefins for Gear Lubrication in Electrical Drives: Aging and Wetting
by Kevin Holderied, Joachim Albrecht, Elisabeth Distler, Katharina Weber and Nahed El Mahallawy
Lubricants 2025, 13(8), 347; https://doi.org/10.3390/lubricants13080347 - 4 Aug 2025
Abstract
Electric propulsion requires engines and transmission systems that run at higher speeds compared to combustion engines. For improving sustainability and environmental protection, biodegradable oils are suggested for the lubrication of high-speed gears that require particularly quick wetting of the steel surfaces. Newly developed [...] Read more.
Electric propulsion requires engines and transmission systems that run at higher speeds compared to combustion engines. For improving sustainability and environmental protection, biodegradable oils are suggested for the lubrication of high-speed gears that require particularly quick wetting of the steel surfaces. Newly developed promising candidates include short-chained polyalphaolefins. In the present work, a study on the applicability of such oil is presented and discussed with respect to different aging levels based on biodegradable properties. It focuses on the wettability of metallic surfaces investigated through time-resolved contact angle measurements. Carbon steels with different carbon contents and microstructures are selected as the most commonly used materials for gears. Effects of steel composition, surface roughness and oil oxidation are studied. The results show that in most cases, the application of biodegradable polyalphaolefins is not critical; however, a combination of steels with inhomogeneous microstructure, high surface roughness and aged oil can be critical because of limited wetting. Full article
(This article belongs to the Special Issue Tribology of Electric Vehicles)
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18 pages, 674 KiB  
Article
Oil Extraction Systems Influence the Techno-Functional and Nutritional Properties of Pistachio Processing By-Products
by Rito J. Mendoza-Pérez, Elena Álvarez-Olmedo, Ainhoa Vicente, Felicidad Ronda and Pedro A. Caballero
Foods 2025, 14(15), 2722; https://doi.org/10.3390/foods14152722 - 4 Aug 2025
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Abstract
Low-commercial-value natural pistachios (broken, closed, or immature) can be revalorised through oil extraction, obtaining a high-quality oil and partially defatted flour as by-product. This study evaluated the techno-functional and nutritional properties of the flours obtained by hydraulic press (HP) and single-screw press (SSP) [...] Read more.
Low-commercial-value natural pistachios (broken, closed, or immature) can be revalorised through oil extraction, obtaining a high-quality oil and partially defatted flour as by-product. This study evaluated the techno-functional and nutritional properties of the flours obtained by hydraulic press (HP) and single-screw press (SSP) systems, combined with pretreatment at 25 °C and 60 °C. The extraction method significantly influenced flour’s characteristics, underscoring the need to tailor processing conditions to the specific technological requirements of each food application. HP-derived flours presented lighter colour, greater tocopherol content, and higher water absorption capacity (up to 2.75 g/g), suggesting preservation of hydrophilic proteins. SSP-derived flours showed higher concentration of protein (44 g/100 g), fibre (12 g/100 g), and minerals, and improved emulsifying properties, enhancing their suitability for emulsified products. Pretreatment at 25 °C enhanced functional properties such as swelling power (~7.0 g/g) and water absorption index (~5.7 g/g). The SSP system achieved the highest oil extraction yield, with no significant effect of pretreatment temperature. The oils extracted showed high levels of unsaturated fatty acids, particularly oleic acid (~48% of ω-9), highlighting their nutritional and industrial value. The findings support the valorisation of pistachio oil extraction by-products as functional food ingredients, offering a promising strategy for reducing food waste and promoting circular economy approaches in the agri-food sector. Full article
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20 pages, 1639 KiB  
Case Report
The Power of Preventive Protection: Effects of Vaccination Strategies on Furunculosis Resistance in Large-Scale Aquaculture of Maraena Whitefish
by Kerstin Böttcher, Peter Luft, Uwe Schönfeld, Stephanie Speck, Tim Gottschalk and Alexander Rebl
Fishes 2025, 10(8), 374; https://doi.org/10.3390/fishes10080374 - 4 Aug 2025
Viewed by 148
Abstract
Furunculosis caused by Aeromonas salmonicida poses a significant challenge to the sustainable production of maraena whitefish (Coregonus maraena). This case report outlines a multi-year disease management strategy at a European whitefish facility with two production departments, each specialising in different life-cycle [...] Read more.
Furunculosis caused by Aeromonas salmonicida poses a significant challenge to the sustainable production of maraena whitefish (Coregonus maraena). This case report outlines a multi-year disease management strategy at a European whitefish facility with two production departments, each specialising in different life-cycle stages. Recurrent outbreaks of A. salmonicida necessitated the development of effective vaccination protocols. Herd-specific immersion vaccines failed to confer protection, while injectable formulations with plant-based adjuvants caused severe adverse reactions and mortality rates exceeding 30%. In contrast, the bivalent vaccine Alpha Ject 3000, containing inactivated A. salmonicida and Vibrio anguillarum with a mineral oil adjuvant, yielded high tolerability and durable protection in over one million whitefish. Post-vaccination mortality remained low (3.3%), aligning with industry benchmarks, and furunculosis-related losses were fully prevented in both departments. Transcriptomic profiling of immune-relevant tissues revealed distinct gene expression signatures depending on vaccine type and time post-vaccination. Both the herd-specific vaccine and Alpha Ject 3000 induced the expression of immunoglobulin and inflammatory markers in the spleen, contrasted by reduced immunoglobulin transcript levels in the gills and head kidney together with the downregulated expression of B-cell markers. These results demonstrate that an optimised injectable vaccination strategy can significantly improve health outcomes and disease resilience in maraena whitefish aquaculture. Full article
(This article belongs to the Special Issue Fish Pathogens and Vaccines in Aquaculture)
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23 pages, 2059 KiB  
Systematic Review
Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis
by Yuntong Zhang, Yunfei Gui, Roger Adams, Joshua Farragher, Catherine Itsiopoulos, Keegan Bow, Ming Cai and Jia Han
Nutrients 2025, 17(15), 2547; https://doi.org/10.3390/nu17152547 - 3 Aug 2025
Viewed by 277
Abstract
Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that can greatly affect quality of life in middle-aged and elderly individuals. Nutritional supplements are increasingly used for KOA due to their low risk, but direct comparative evidence on their efficacy and [...] Read more.
Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that can greatly affect quality of life in middle-aged and elderly individuals. Nutritional supplements are increasingly used for KOA due to their low risk, but direct comparative evidence on their efficacy and safety remains scarce. This study aimed to systematically compare the effectiveness and safety of seven common nutritional supplements for KOA. Methods: A systematic review and network meta-analysis were conducted following PRISMA guidelines. Embase, PubMed, and the Cochrane Library were searched through December 2024 for randomized controlled trials (RCTs) evaluating use of eggshell membrane, vitamin D, Boswellia, curcumin, ginger, krill oil, or collagen, versus placebo, in adults with KOA. Primary outcomes included changes in scores for WOMAC pain, stiffness and function, and pain visual analog scale (VAS). Adverse events were also assessed. Bayesian network meta-analyses estimated ranking probabilities for each intervention. Results: In total, 39 RCTs (42 studies; 4599 patients) were included. Compared with placebo, Boswellia showed significant improvements in WOMAC pain (mean difference [MD] = 10.58, 95% CI: 6.45 to 14.78, p < 0.05), stiffness (MD = 9.47, 95% CI: 6.39 254 to 12.74, p < 0.05), function (MD = 14.00, 95% CI: 7.74 to 20.21, p < 0.05), and VAS pain (MD = 17.26, 95% CI: 8.06 to 26.52, p < 0.05). Curcumin, collagen, ginger, and krill oil also demonstrated benefits in some outcomes. No supplement was associated with increased adverse events compared to placebo. Bayesian rankings indicated Boswellia had the highest probability of being most effective for pain and stiffness, with krill oil and curcumin showing potential for function improvement. Conclusions: Nutritional supplements, particularly Boswellia, appear to be effective and well-tolerated for improving KOA symptoms and function. These results suggest that certain supplements may be useful as part of non-pharmacological KOA management. However, further large-scale, well-designed randomized controlled trials (RCTs) are needed to confirm these findings, particularly those that include more standardized dosages and formulations, as well as to evaluate their long-term efficacy. Full article
(This article belongs to the Section Nutrition Methodology & Assessment)
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