Search Results (504)

In the earthquakes that occurred in the Pazarcık (Mw = 7.7) and Elbistan (Mw = 7.6) districts of Kahramanmaraş Province on 6 February 2023, many buildings collapsed in the Hayrullah neighborhood of the Onikişubat district. In this study, we investigated whether there was a soil amplification effect on the damage occurring in the Hayrullah neighborhood of the Onikişubat district of Kahramanmaraş Province. Firstly, borehole, SPT, MASW (multi-channel surface wave analysis), microtremor, electrical resistivity tomography (ERT), and vertical electrical sounding (VES) tests were carried out in the field to determine the engineering properties and behavior of soil. Laboratory tests were also conducted using samples obtained from bore holes and field tests. Then, an idealized soil profile was created using the laboratory and field test results, and site dynamic soil behavior analyses were performed on the extracted profile. According to The Turkish Building Code (TBC 2018), the earthquake level DD-2 design spectra of the project site were determined and the average design spectrum was created. Considering the seismicity of the project site and TBC (2018) criteria (according to site-specific faulting, distance, and average shear wave velocity), 11 earthquake ground motion sets were selected and harmonized with DD-2 spectra in short, medium, and long periods. Using scaled motions, the soil profile was excited with 22 different earthquake scenarios and the results were obtained for the equivalent and non-linear models. The analysis showed that the soft soil conditions in the area amplified ground shaking by up to 2.8 times, especially for longer periods (1.0–2.5 s). This level of amplification was consistent with the damage observed in mid- to high-rise buildings, highlighting the important role of local site effects in the structural losses seen during the Kahramanmaraş earthquakes. Full article

Relict fern species, confined to microhabitats with stable historical conditions, are especially vulnerable to climate change. The Alboran Arc hosts a unique relict fern flora, including Culcita macrocarpa, Diplazium caudatum, and Pteris incompleta, and functions as a major Pleistocene refuge. This study assesses the population trends and climate sensitivity of these species in Los Alcornocales Natural Park using annual abundance time series for a decade, empirical survival projections, and principal component analysis to identify key climatic drivers. Results reveal distinct climate response clusters among populations, though intra-specific variation highlights the importance of local conditions. Climate change is already impacting population viability, especially for P. incompleta, which shows high sensitivity to rising maximum temperatures and prolonged heatwaves. Climate-driven models forecast more severe declines than empirical ones, particularly for C. macrocarpa and P. incompleta, with the latter showing a projected collapse by the mid-century. In contrast, D. caudatum exhibits moderate vulnerability. Crucially, the divergence between models underscores the impact of conservation efforts: without reinforcement and reintroduction actions, projected declines would likely be more severe. These results project a decline in the populations of the studied ferns, highlighting the urgent need to continue implementing both in situ and ex situ conservation measures. Full article

There has been growing interest in constructing mid- and high-rise wooden buildings in recent years. To ensure the feasibility of these structures, it is necessary to provide evidence that their long-term reliability can be guaranteed. While long-term testing is typically necessary, a continuous monitoring system for the moisture content of wood materials used in buildings has been proposed as an alternative. The proposed method measures the change in the local moisture content using the equilibrium moisture content calculated from the temperature and humidity measured using temperature and humidity sensors. The study used Japanese cypress specimens with dimensions of 50 mm, 75 mm, and 100 mm cubes and Douglas fir specimens of 50 mm cubes. The moisture content was measured under various external environments. Results showed that this system effectively captured changes in local moisture content, reflecting fluctuations in temperature and humidity in a controlled thermo-hygrostat over a three-day moisture absorption environment (20 °C, 95% humidity). Additionally, it was observed that higher moisture content levels yielded correspondingly higher local moisture content measurements compared to those obtained using the oven-drying method. Full article

Recent archaeological discoveries across the Aegean, Cyprus, and western Anatolia have renewed interest in pre-Neolithic seafaring and early island colonization. However, the environmental contexts that support such early coastal occupations remain poorly understood, largely due to the submergence of Pleistocene shorelines following post-glacial sea-level rise. This study addresses this gap through an integrated geoarchaeological investigation of the pre-Neolithic site of Ouriakos on Lemnos Island, northeastern Aegean (Greece), dated to the mid-11th millennium BCE. By reconstructing both the terrestrial and submerged paleolandscapes of the site, we examine ecological conditions, resource availability, and sedimentary processes that shaped human activity and site preservation. Employing a multiscale methodological approach—combining bathymetric survey, geomorphological mapping, soil micromorphology, geochemical analysis, and Optically Stimulated Luminescence (OSL) dating—we present a comprehensive framework for identifying and interpreting early coastal settlements. Stratigraphic evidence reveals phases of fluvial, aeolian, and colluvial deposition associated with an alternating coastline. The core findings reveal that Ouriakos was established during a phase of environmental stability marked by paleosol development, indicating sustained human presence. By bridging terrestrial and marine data, this research contributes significantly to the understanding of human coastal mobility during the Pleistocene–Holocene transition. Full article

Alzheimer’s disease (AD) is increasingly recognized as a multifactorial disorder driven by a combination of disruptions in proteostasis and organelle communication. The 2020 Lancet commission reported that approximately 10 million people worldwide were affected by AD in the mid-20th century. AD is the most prevalent cause of dementia. By early 2030, the global cost of dementia is projected to rise by USD 2 trillion per year, with up to 85% of that cost attributed to daily patient care. Several factors have been implicated in the progression of neurodegeneration, including increased oxidative stress, the accumulation of misfolded proteins, the formation of amyloid plaques and aggregates, the unfolded protein response (UPR), and mitochondrial–endoplasmic reticulum (ER) calcium homeostasis. However, the exact triggers that initiate these pathological processes remain unclear, in part because clinical symptoms often emerge gradually and subtly, complicating early diagnosis. Among the early hallmarks of neurodegeneration, elevated levels of reactive oxygen species (ROS) and the buildup of misfolded proteins are believed to play pivotal roles in disrupting proteostasis, leading to cognitive deficits and neuronal cell death. The accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles is a characteristic feature of AD. These features contribute to chronic neuroinflammation, which is marked by the release of pro-inflammatory cytokines and chemokines that exacerbate oxidative stress. Given these interconnected mechanisms, targeting stress-related signaling pathways, such as oxidative stress (ROS) generated in the mitochondria and ER, ER stress, UPR, and cytosolic chaperones, represents a promising strategy for therapeutic intervention. This review focuses on the relationship between stress chaperone responses and organelle function, particularly the interaction between mitochondria and the ER, in the development of new therapies for AD and related neurodegenerative disorders. Full article

Objectives: To assess the clinical and inflammatory outcomes of patients with calcified coronary arteries treated with rotational atherectomy (RA), compared to those with other intervention procedures. Methods: We conducted a systematic search of PubMed (Medline) and Embase. This review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and applied the PICO criteria. Results: A total of 110 articles were analyzed, comprising 2,328,417 patients with moderate to severe coronary calcified lesions treated with RA, conventional percutaneous coronary intervention (PCI), or other advanced interventions. The pooled incidence of short- to mid-term major adverse cardiovascular events (MACEs) was 6% (95% CI 4–7%), increasing to 17% (95% CI 15–21%) at 6 months. Mortality was 2% (95% CI 1–3%) within 6 months, rising to 7% (95% CI 6–9%) thereafter. RA significantly increased the risk of long-term MACEs, mortality, total lesion revascularization (TLR), bleeding, and fluoroscopy time, and was borderline associated with an increased risk of short-term myocardial infarction and a reduced risk of coronary dissection. RA and other invasive procedures showed similar risks for short-term MACEs, mortality, total vascular revascularization (TVR), stent thrombosis, heart failure, stroke, and inflammation. Conclusions: RA is linked to higher long-term risks of MACEs, mortality, TLR, bleeding, and fluoroscopy time compared to other interventions. While RA shows comparable outcomes for short-term MACEs and mortality with other procedures, it may slightly reduce the risk of coronary dissection. These findings underscore the importance of careful patient selection and weighing long-term risks when considering RA for calcified coronary lesions. Full article

The global climate crisis has driven unprecedented agreements among nations on carbon mitigation. With China’s commitment to carbon peaking and carbon neutrality targets, the building sector has emerged as a critical focus for emission reduction, particularly because office buildings account for over 30% of building energy consumption. However, a systematic and regionally adaptive low-carbon technology evaluation framework is lacking. To address this gap, this study develops a multidimensional decision-making system to quantify and rank low-carbon technologies for office buildings in Beijing. The method includes four core components: (1) establishing three archetypal models—low-rise (H ≤ 24 m), mid-rise (24 m < H ≤ 50 m), and high-rise (50 m < H ≤ 100 m) office buildings—based on 99 office buildings in Beijing; (2) classifying 19 key technologies into three clusters—Envelope Structure Optimization, Equipment Efficiency Enhancement, and Renewable Energy Utilization—using bibliometric analysis and policy norm screening; (3) developing a four-dimensional evaluation framework encompassing Carbon Reduction Degree (CRD), Economic Viability Degree (EVD), Technical Applicability Degree (TAD), and Carbon Intensity Degree (CID); and (4) conducting a comprehensive quantitative evaluation using the AHP-entropy-TOPSIS algorithm. The results indicate distinct priority patterns across the building types: low-rise buildings prioritize roof-mounted photovoltaic (PV) systems, LED lighting, and thermal-break aluminum frames with low-E double-glazed laminated glass. Mid- and high-rise buildings emphasize integrated PV-LED-T8 lighting solutions and optimized building envelope structures. Ranking analysis further highlights LED lighting, T8 high-efficiency fluorescent lamps, and rooftop PV systems as the top-recommended technologies for Beijing. Additionally, four policy recommendations are proposed to facilitate the large-scale implementation of the program. This study presents a holistic technical integration strategy that simultaneously enhances the technological performance, economic viability, and carbon reduction outcomes of architectural design and renovation. It also establishes a replicable decision-support framework for decarbonizing office and public buildings in cities, thereby supporting China’s “dual carbon” goals and contributing to global carbon mitigation efforts in the building sector. Full article

Over recent decades, phase-change materials (PCMs) have gained prominence as latent-heat thermal energy storage systems in building envelopes because of their high energy density. However, only PCMs that complete a full daily charge–discharge cycle can deliver meaningful energy and carbon-emission savings. This simulation study introduces a methodology that simultaneously optimizes PCM integration for storage efficiency, indoor thermal comfort, and energy savings. Two new indicators are proposed: overall storage efficiency (EC_n), which consolidates heating and cooling-efficiency ratios into a single value, and the performance factor (PF), which quantifies the PCM’s effectiveness in maintaining thermal comfort. Using EnergyPlus v8.9 coupled with DesignBuilder, a residential ASHRAE 90.1 mid-rise apartment was modeled in six warm-temperate (Cfb) European cities for the summer period from June 1 to August 31. Four paraffin PCMs (RT-22/25/28/31 HC, 20 mm thickness) were tested under natural and controlled ventilation strategies, with windows opening 50% when outdoor air was at least 2 °C cooler than indoors. Simulation outputs were validated against experimental cubicle data, yielding a mean absolute indoor temperature error ≤ 4.5%, well within the ±5% tolerance commonly accepted for building thermal simulations. The optimum configuration—RT-25 HC with temperature-controlled ventilation—achieved PF = 1.0 (100% comfort compliance) in all six cities and delivered summer cooling-energy savings of up to 3376 kWh in Paris, the highest among the locations studied. Carbon-emission reductions reached 2254 kg CO₂-e year⁻¹, and static payback periods remained below the assumed 50-year building life at a per kg PCM cost of USD 1. The EC_n–PF framework, therefore, provides a transparent basis for selecting cost-effective, energy-efficient, and low-carbon PCM solutions in warm-temperate buildings. Full article

On 22 May 2012, a magnitude Mw 5.6 earthquake struck the Pernik region of western Bulgaria, causing structural damage in nearby cities, including Sofia. This study assesses the seismic response of a six-story reinforced concrete building in central Sofia, utilizing real accelerogram data recorded at the basement (SGL1) and sixth floor (SGL2) levels during the earthquake. Using the Kanai–Yoshizawa (KY) model, the study estimates inter-story motion and assesses amplification effects across the structure. Analysis of peak ground acceleration (PGA), velocity (PGV), displacement (PGD), and spectral ratios reveals significant dynamic amplification of peak ground acceleration and displacement on the sixth floor, indicating flexible and dynamic behavior, as well as potential resonance effects. The analysis combines three spectral techniques—Horizontal-to-Vertical Spectral Ratio (H/V), Floor Spectral Ratio (FSR), and the Random Decrement Method (RDM)—to determine the building’s dynamic characteristics, including natural frequency and damping ratio. The results indicate a dominant vibration frequency of approximately 2.2 Hz and damping ratios ranging from 3.6% to 6.5%, which is consistent with the typical damping ratios of mid-rise concrete buildings. The findings underscore the significance of soil–structure interaction (SSI), particularly in sedimentary basins like the Sofia Graben, where localized geological effects influence seismic amplification. By integrating accelerometric data with advanced spectral techniques, this research can enhance ongoing site-specific monitoring and seismic design practices, contributing to the refinement of earthquake engineering methodologies for mitigating seismic risk in earthquake-prone urban areas. Full article

Change in sea level (SL) is an important indicator of global warming, since it reflects alterations in several components of the climate system at once. The main factors behind this phenomenon are the melting of glaciers and thermal expansion of ocean water, with the latter contributing about 40% to the overall rise in SL. Rising SL indirectly indicates an increase in ocean heat content and, consequently, its surface temperature. Previous studies have found that tropical sea surface temperature (SST) is critical to regulating the Earth’s climate and weather patterns in high and mid-latitudes. For this reason, SST and SL in the tropics can be considered as precursors of both global climate change and the emergence of climate anomalies in extratropical latitudes. Although SST has been used in this capacity in a number of studies, similar research regarding SL had not been conducted until recently. In this paper, we examine the links between SL in the tropical North Atlantic and North Pacific Oceans and surface air temperature (SAT) at mid- and high latitudes, with the aim of assessing the potential of SL as a predictor in forecasting SAT anomalies. To identify similarities between the variability of tropical SL and SST and that of SAT in high- and mid-latitude regions, as well as to estimate possible time lags, we applied factor analysis, clustering, cross-correlation and cross-spectral analyses. The results reveal a structural similarity in the internal variability of tropical SL and extratropical SAT, along with a significant lagged relationship between them, with a time lag of several years. Full article

Under accelerating global warming, the northern slope of the Middle Kunlun Mountains in Xinjiang, China, has seen a marked rise in extreme rainfall, posing increasing challenges for flood risk management and water resources. To improve our predictive capabilities and deepen our understanding of the driving mechanisms, we combine the European Centre for Medium-Range Weather Forecasts Reanalysis-5 (ERA5) reanalysis, regional observations, and high-resolution Weather Research and Forecasting model (WRF) simulations to dissect the 14–17 June 2021, extreme rainfall event. A deep Siberia–Central Asia trough and nascent Central Asian vortex established a coupled upper- and low-level jet configuration that amplified large-scale ascent. Embedded shortwaves funnelled abundant moisture into the orographic basin, where strong low-level moisture convergence and vigorous warm-sector updrafts triggered and sustained deep convection. WRF reasonably replicated observed wind shear and radar echoes, revealing the descent of a mid-level jet into an ultra-low-level jet that provided a mesoscale engine for storm intensification. Momentum–budget diagnostics underscore the role of meridional momentum transport along sloping terrain in reinforcing low-level convergence and shear. Together, these synoptic-to-mesoscale interactions and moisture dynamics led to this landmark extreme-precipitation event. Full article

On-chip spectral splitting structures with compact footprints hold tremendous potential for next-generation molecular sensing applications in the mid-infrared region. Here, we propose and theoretically investigate a carefully designed structure comprising a tilt grating and metalenses for dual-band spectral splitting with enhanced bandwidth. The tilt grating serves to separate the wavelength bands, and the metalenses following the grating guarantee a smooth transition of light into single-mode waveguides, giving rise to transmittances of 73.59% at 4 μm and 68.74% at 11 μm. The use of this tandem structure results in a significant footprint reduction and a remarkable 25.8% bandwidth enhancement over conventional approaches. The proposed spectral splitting scheme, with its broad wavelength range applicability, unlocks new pathways for on-chip simultaneous multi-target molecule detection. Full article

The city of Al Ain is a fast-developing area. With building typology varying from low-rise to mid-rise, sustainable design in buildings is needed. As the majority of the city’s population is Emirati Citizens, the percentage of expats is increasing. The expats tend to live in mid-rise buildings. One of the central midrise areas is AL Ain Square. This study aims to investigate how an optimized mashrabiya pattern can impact the energy and the Predicted Mean Vote (PMV) in a 3-bedroom apartment, fully oriented to the south, of an expat family. The methodology is as follows: case study selection, Weather analysis, Modeling/Validation of the base case scenario, Optimization of the mashrabiya pattern, Simulation of various scenarios, and Results. Analyzing the selected case study is the initial step of the methodology. This analysis begins with the district, building typology, and the chosen apartment. The weather analysis is relevant for using the mashrabiya (screen device) and the need to improve energy consumption and thermal comfort. The modeling of the base case shall be performed in Rhino Grasshopper. The validation is based on a one-year electricity bill provided by the owner. The optimization of mashrabiya patterns is an innovative process, where various designs are compared and then optimized to select the most efficient pattern. The solutions to the selected scenarios will then yield the results of the optimal scenario. This study is relevant to industry, academia, and local authorities as an innovative approach to retrofitting buildings. Additionally, the research presents a creative vision that suggests optimized mashrabiya patterns can significantly enhance energy savings, with the hexagonal grid configuration demonstrating the highest efficiency. This finding highlights the potential for geometry-driven shading optimization tailored to specific climatic and building conditions. Contrasting earlier mashrabiya studies that assess one static pattern, we couple a geometry-agnostic evolutionary solver with a utility-calibrated EnergyPlus model to test thousands of square, hexagonal, and triangular permutations. This workflow uncovers a previously undocumented non-linear depth perforation interaction. It validates a hexagonal screen that reduces annual cooling energy by 12.3%, establishing a replicable, grid-specific retrofit method for hot-arid apartments. Full article

Expansive clays damage the foundations, slabs, and utilities of low- and mid-rise buildings, threatening daily operations and incurring billions of dollars in costs globally. This study pioneers a domain-informed machine learning framework, coupled with a collinearity-aware feature selection strategy, to predict soil swell potential solely from routine index properties. Following hard-limit filtering and Unified Soil Classification System (USCS) screening, 291 valid samples were extracted from a public dataset of 395 cases. A random forest benchmark model was developed using five correlated features, and a multicollinearity analysis, as indicated by the variance inflation factor, revealed exact linear dependence among the Atterberg limits. A parsimonious two-variable model, based solely on plasticity index (PI) and clay fraction (C), was retained. On an 80:20 stratified hold-out set, this simplified model reduced root mean square error (RMSE) from 9.0% to 6.8% and maximum residuals from 42% to 16%. Bootstrap analysis confirmed a median RMSE of 7.5% with stable 95% prediction intervals. Shapley Additive Explanations (SHAP) analysis revealed that PI accounted for approximately 75% of the model’s influence, highlighting the critical swell surge beyond PI ≈ 55%. This work introduces a rule-based cleaning pipeline and collinearity-aware feature selection to derive a robust, two-variable model balancing accuracy and interpretability, a lightweight, interpretable tool for foundation design, GIS zoning, and BIM workflows. Full article

Snow cover, as a critical component of the cryosphere, serves as a vital water resource for arid regions in Northwest China. The Qilian Mountains (QLM), situated on the northeastern margin of the Tibetan Plateau, function as an important ecological barrier and water conservation area in western China. This study presents the first high-resolution historical snow cover product developed specifically for the QLM, utilizing a multi-level snow classification algorithm tailored to the complex topography of the region. By employing Landsat satellite data from 1986–2024, we constructed a comprehensive 39-year snow cover dataset at a resolution of 30 m. A dual adaptive cloud masking strategy and spatial interpolation techniques were employed to effectively address cloud contamination and data gaps prevalent in mountainous regions. The spatiotemporal characteristics and driving mechanisms of snow cover changes in the QLM were systematically analyzed using Sen–Theil trend analysis and Mann–Kendall tests. The results reveal the following: (1) The mean annual snow cover extent in the QLM was 15.73% during 1986–2024, exhibiting a slight declining trend (−0.046% yr⁻¹), though statistically insignificant (p = 0.215); (2) The snowline showed significant upward migration, with mean elevation and minimum elevation rising at rates of 3.98 m yr⁻¹ and 2.81 m yr⁻¹, respectively; (3) Elevation-dependent variations were observed, with significant snow cover decline in high-altitude (>5000 m) and low-altitude (2000–3500 m) regions, while mid-altitude areas remained relatively stable; (4) Comparison with MODIS data demonstrated good correlation (r = 0.828) but revealed systematic differences (RMSE = 12.88%), with MODIS showing underestimation in mountainous environments (Bias: −8.06%). This study elucidates the complex response mechanisms of the QLM snow system under global warming, providing scientific evidence for regional water resource management and climate change adaptation strategies. Full article