Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (28)

Search Parameters:
Keywords = lens surface pressure

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
47 pages, 20952 KB  
Review
Bioinspired Heat Exchangers: A Multi-Scale Review of Thermo-Hydraulic Performance Enhancement
by Hyunsik Yang, Jinhyun Pi, Soyoon Park and Wongyu Bae
Biomimetics 2026, 11(1), 76; https://doi.org/10.3390/biomimetics11010076 - 16 Jan 2026
Viewed by 98
Abstract
Heat exchangers are central to energy and process industries, yet performance is bounded by the trade-off between higher heat transfer and greater pressure drop. This review targets indirect-type heat exchangers and organizes bioinspired strategies through a multi-scale lens of surface, texture, and network [...] Read more.
Heat exchangers are central to energy and process industries, yet performance is bounded by the trade-off between higher heat transfer and greater pressure drop. This review targets indirect-type heat exchangers and organizes bioinspired strategies through a multi-scale lens of surface, texture, and network scales. It provides a structured comparison of their thermo-hydraulic behaviors and evaluation methods. At the surface scale, control of wettability and liquid-infused interfaces suppresses icing and fouling and stabilizes condensation. At the texture scale, microstructures inspired by shark skin and fish scales regulate near-wall vortices to balance drag reduction with heat-transfer enhancement. At the network scale, branched and bicontinuous pathways inspired by leaf veins, lung architectures, and triply periodic minimal surfaces promote uniform distribution and mixing, improving overall performance. The survey highlights practical needs for manufacturing readiness, durability, scale-up, and validation across operating ranges. By emphasizing analysis across scales rather than reliance on a single metric, the review distills design principles and selection guidelines for next-generation bioinspired heat exchangers. Full article
20 pages, 10791 KB  
Article
Developing Integrated Supersites to Advance the Understanding of Saltwater Intrusion in the Coastal Plain Between the Brenta and Adige Rivers, Italy
by Luigi Tosi, Marta Cosma, Pablo Agustín Yaciuk, Iva Aljinović, Andrea Artuso, Jadran Čarija, Cristina Da Lio, Lorenzo Frison, Veljko Srzić, Fabio Tateo and Sandra Donnici
J. Mar. Sci. Eng. 2025, 13(12), 2328; https://doi.org/10.3390/jmse13122328 - 8 Dec 2025
Viewed by 291
Abstract
Saltwater intrusion increasingly jeopardizes groundwater in low-lying coastal plains worldwide, where the combined effects of sea-level rise, land subsidence, and hydraulic regulation further exacerbate aquifer vulnerability and threaten the long-term sustainability of freshwater supplies. To move beyond sparse and fragmented piezometric observations, we [...] Read more.
Saltwater intrusion increasingly jeopardizes groundwater in low-lying coastal plains worldwide, where the combined effects of sea-level rise, land subsidence, and hydraulic regulation further exacerbate aquifer vulnerability and threaten the long-term sustainability of freshwater supplies. To move beyond sparse and fragmented piezometric observations, we propose “integrated coastal supersites”: wells equipped with multiparametric sensors and multilevel piezometers that couple high-resolution vertical conductivity–temperature–depth (CTD) profiling with continuous hydro-meteorological time series to monitor the hydrodynamic behavior of coastal aquifers and saltwater intrusion. This study describes the installation of two supersites and presents early insights from the first monitoring period, which, despite a short observation window limited to the summer season (July–September 2025), demonstrate the effectiveness of this approach. Two contrasting supersites were deployed in the coastal plain between the Brenta and Adige Rivers (Italy): Gorzone, characterized by a thick, laterally persistent aquitard, and Buoro, where the aquitard is thinner and discontinuous. Profiles and fixed sensors at both sites reveal a consistent fresh-to-saline transition in the phreatic aquifers and a secondary freshwater lens capping the confined systems. At Gorzone, the confining layer hydraulically isolates the deeper aquifer, preserving low salinity beneath a saline, tidally constrained phreatic zone. Groundwater heads oscillate by about 0.2 m, and rainfall events do not dilute salinity; instead, pressure transients—amplified by drainage regulation and inland-propagating tides—induce short-lived EC increases via upconing. Buoro shows smaller water-level variations, not always linked to rainfall, and, in contrast, exhibits partial vertical connectivity and faster dynamics: phreatic heads respond chiefly to internal drainage and local recharge, with rises rapidly damped by pumping, while salinity remains steady without episodic peaks. The confined aquifer shows buffered, delayed responses to surface forcings. Although the monitoring window is currently limited to 2025 through the summer season, these results offer compelling evidence that coastal supersites are reliable, scalable, and management-critical relevance platforms for groundwater calibration, forecasting, and long-term assessment. Full article
(This article belongs to the Special Issue Monitoring Coastal Systems and Improving Climate Change Resilience)
Show Figures

Graphical abstract

21 pages, 5733 KB  
Article
Salinity Distribution as a Hydrogeological Limit in a Karstic Watershed in Yucatan
by Iris Neri-Flores, Ojilve Ramón Medrano-Pérez, Flor Arcega-Cabrera, Ismael Mariño-Tapia, César Canul-Macario and Pedro Agustín Robledo-Ardila
J. Mar. Sci. Eng. 2025, 13(12), 2317; https://doi.org/10.3390/jmse13122317 - 6 Dec 2025
Viewed by 527
Abstract
In coastal regions, the interaction between freshwater and seawater creates a dynamic system in which the spatial distribution of salinity critically constrains the use of freshwater for human consumption. Although saline intrusion is a globally widespread phenomenon, its inland extent varies significantly with [...] Read more.
In coastal regions, the interaction between freshwater and seawater creates a dynamic system in which the spatial distribution of salinity critically constrains the use of freshwater for human consumption. Although saline intrusion is a globally widespread phenomenon, its inland extent varies significantly with hydrological conditions, posing a persistent threat to groundwater quality and sustainability. This study aimed to characterize salinity distribution using an integrated karst-watershed approach, thereby enabling the identification of both lateral and vertical salinity gradients. The study area is in the northwestern Yucatan Peninsula. Available hydrogeological data were analyzed to determine aquifer type, soil texture, evidence of saline intrusion, seawater fraction, vadose zone thickness, and field measurements. These included sampling from 42 groundwater sites (open sinkholes and dug wells), which indicated a fringe zone approximately 5 km in size influenced by seawater interaction, in mangrove areas and in three key zones of salinity patterns: west of Mérida (Celestun and Chunchumil), and northern Yucatan (Sierra Papacal, Motul, San Felipe). Vertical Electrical Sounding (VES) and conductivity profiling in two piezometers indicated an apparent seawater influence. The interface was detected at a depth of 28 m in Celestun and 18 m in Chunchumil. These depths may serve as hydrogeological thresholds for freshwater abstraction. Results indicate that saltwater can extend several kilometers inland, a factor to consider when evaluating freshwater availability. This issue is particularly critical within the first 20 km from the coastline, where increasing tourism exerts substantial pressure on groundwater reserves. A coastal-to-inland salinity was identified, and an empirical equation was proposed to estimate the seawater fraction (fsea%) as a function of distance from the shoreline in the Cenote Ring trajectory. Vertically, a four-layer model was identified in this study through VES in the western watershed: an unsaturated zone approximately 2.6 m thick, a confined layer in the coastal Celestun profile about 9 m thick, a freshwater lens floating above a brackish layer between 8 and 25 m, and a saline interface at 37 m depth. The novelty of this study, in analyzing all karstic water surfaces together as a system, including the vadose zone and the aquifer, and considering the interactions with the surface, is highlighted by the strength of this approach. This analysis provides a better understanding and more precise insight into the integrated system than analyzing each component separately. These findings have significant implications for water resource management in karst regions such as Yucatan, underscoring the urgent need for sustainable groundwater management practices to address seawater intrusion. Full article
(This article belongs to the Special Issue Marine Karst Systems: Hydrogeology and Marine Environmental Dynamics)
Show Figures

Graphical abstract

16 pages, 1652 KB  
Article
Evaluation of Dry Eye Disease Signs, Symptoms, and Vision-Related Quality of Life in Patients with Systemic Lupus Erythematosus
by Wojciech Luboń, Anna Agaś-Lange, Ewa Mrukwa-Kominek, Adrian Smędowski and Dorota Wyględowska-Promieńska
Life 2025, 15(9), 1423; https://doi.org/10.3390/life15091423 - 10 Sep 2025
Cited by 1 | Viewed by 1403
Abstract
Dry eye disease (DED) represents one of the most prevalent ocular manifestations associated with systemic lupus erythematosus (SLE), with reported incidence rates ranging from 15% to 35%. DED constitutes a multifactorial condition that significantly impairs both visual function and health-related quality of life. [...] Read more.
Dry eye disease (DED) represents one of the most prevalent ocular manifestations associated with systemic lupus erythematosus (SLE), with reported incidence rates ranging from 15% to 35%. DED constitutes a multifactorial condition that significantly impairs both visual function and health-related quality of life. The objective of this study was to assess the impact of DED symptoms on vision-related quality of life in patients diagnosed with SLE, employing the Ocular Surface Disease Index (OSDI) as a disease-specific instrument. Additionally, the study aimed to evaluate correlations between clinical diagnostic tests and OSDI scores, and to determine the frequency of abnormalities affecting individual ocular structures. This study included 35 SLE patients, identifying DED in 37.1%. Common ophthalmic abnormalities included lens opacification (22.9%) and hyaloid degeneration (34.3%). Astigmatism (>0.50 D cyl) was prevalent (60.0%), being significantly higher in DED patients. While visual acuity and intraocular pressure were comparable, DED patients showed significantly lower Schirmer I test values, reduced tear break-up time, and higher van Bijsterveld scores, indicating impaired tear film and surface integrity. OSDI scores were significantly elevated in the DED group, with 51.4% reporting moderate to severe dysfunction. Strong, statistically significant correlations between the OSDI and objective tear film parameters confirmed a robust association between subjective symptoms and clinical signs. These findings highlight the significant impact of DED on visual function in SLE patients, underscoring the importance of routine ophthalmological evaluation and timely intervention. Full article
(This article belongs to the Section Medical Research)
Show Figures

Figure 1

13 pages, 3677 KB  
Article
Surface Topography Analysis of BK7 with Different Roughness Nozzles Using an Abrasive Water Jet
by Haihong Pan, Xuhong Chen, Lin Chen, Hui You and Xubin Liang
Materials 2024, 17(18), 4494; https://doi.org/10.3390/ma17184494 - 13 Sep 2024
Cited by 2 | Viewed by 1483
Abstract
This study investigated the effect of abrasive water jet (AWJ) kinematic parameters, such as jet traverse speed and water pressure, abrasive mass flow rate, and standoff distance on the surface of BK7. Nozzle A reinforced with a 100 nm particle-sized coating of titanium [...] Read more.
This study investigated the effect of abrasive water jet (AWJ) kinematic parameters, such as jet traverse speed and water pressure, abrasive mass flow rate, and standoff distance on the surface of BK7. Nozzle A reinforced with a 100 nm particle-sized coating of titanium alloy has more wear resistance compared to Nozzle B coated with nothing. Through analysis of variance and measurement of BK7 surface quality, it is concluded that the grooving and plowing caused by abrasive particles and irregularities in the abrasive water jet machined surface with respect to traverse speed (3, 7.2, 7.8, and 9 mm/min), abrasive flow rate (7 L/min and 10 L/min, 80 mesh) and water pressure (2 and 3 MPa) were investigated using surface topography measurements. The surface roughness (15.734 nm) of BK7 results show that a nozzle coated with titanium alloy has more hardness, which protects BK7 undamaged and super-smooth. The values of selected surface roughness profile parameters—average roughness (Ra) and maximum height of PV (maximum depth of peak and valleys)—reveal a comparatively smooth BK7 surface in composites reinforced with 2% titanium alloy in the nozzle weight at a traverse speed of 7.8 mm/min. Moreover, abrasive water jet machining at high water pressure (3 MPa) produced better surface quality due to material removal and effective cleaning of lens fragmentation and abrasive particles from the polishing zone compared to a lower water pressure (2 MPa), low traverse speed (5 mm/min), and low abrasive mass flow rate (200 g/min). Full article
(This article belongs to the Section Manufacturing Processes and Systems)
Show Figures

Figure 1

15 pages, 7344 KB  
Article
The Effect of 0–8 MPa Environmental Pressure on the Ignition and Combustion Process of CL20/NEPE Solid Propellant
by Wenxiang Cai, Wei Li and Zhixiang Wang
Aerospace 2024, 11(8), 672; https://doi.org/10.3390/aerospace11080672 - 15 Aug 2024
Cited by 1 | Viewed by 1823
Abstract
In order to study the effect of pressure on the ignition and combustion process of CL-20/NEPE solid propellant, the ignition delay, burning rate, and maximum combustion temperature of different solid propellant formulations with an ambient pressure of 0.1~8.0 MPa were measured experimentally by [...] Read more.
In order to study the effect of pressure on the ignition and combustion process of CL-20/NEPE solid propellant, the ignition delay, burning rate, and maximum combustion temperature of different solid propellant formulations with an ambient pressure of 0.1~8.0 MPa were measured experimentally by a solid propellant laser ignition experiment system, and the agglomeration process and the characteristics of condensed phase combustion products were analyzed. The experimental results show that, with the increase of pressure, the ignition-delay time decreases, and the burning rate and the maximum combustion temperature increase. With the increase of pressure, the influence on propellant ignition and combustion characteristics becomes smaller. In the experiment, the dynamic agglomeration phenomenon of aluminum particles in the propellant was recorded by a high-speed camera combined with a microscopic camera lens, and the dynamic agglomeration phenomenon of the combustion surface of the propellant and the dynamic agglomeration phenomenon, after the initial agglomeration was separated from the surface, were analyzed and expounded. Based on the experiment and combined with the agglomeration phenomenon, a mathematical model capable of predicting the particle size of aluminum aggregates was proposed. Full article
(This article belongs to the Special Issue Combustion of Solid Propellants)
Show Figures

Figure 1

24 pages, 4644 KB  
Review
Artificial Ground Freezing—On the Soil Deformations during Freeze–Thaw Cycles
by Zeina Joudieh, Olivier Cuisinier, Adel Abdallah and Farimah Masrouri
Geotechnics 2024, 4(3), 718-741; https://doi.org/10.3390/geotechnics4030038 - 4 Jul 2024
Cited by 6 | Viewed by 5769
Abstract
Artificial ground freezing (AGF) has emerged as a prominent treatment method due to its ability to mechanically strengthen the soil while reducing its permeability. However, its implementation has raised concerns about its impact, particularly with respect to frost heave and subsequent thaw-induced displacements. [...] Read more.
Artificial ground freezing (AGF) has emerged as a prominent treatment method due to its ability to mechanically strengthen the soil while reducing its permeability. However, its implementation has raised concerns about its impact, particularly with respect to frost heave and subsequent thaw-induced displacements. These soil movements can cause subsidence and pose a significant threat to the integrity of surface structures. Overburden pressure plays a crucial role in AGF and determines the amount of heave generated. This paper presents an analysis of the existing literature about soil freezing and thawing. The aim is to offer an understanding of these processes, specifically with regard to their application in AGF. This paper explains the behavior of soil during freezing, with particular emphasis on the influence of overburden pressure. It also investigates frozen soils’ thawing and freeze–thaw (FT) cycles’ long-term effects on soil properties. AGF offers improved soil strength and reduced water permeability, enhancing construction project stability. However, the interplay between the temperature, soil composition, and initial ground conditions during freezing is complex. This thermo-hydro-chemo-mechanical process strengthens the soil and reduces its permeability, but it can also induce frost heave due to water expansion and ice lens formation. Overburden pressure from the overlying soil limits ice lens growth. FT cycles significantly impact soil properties. In fine-grained soils, FT cycles can lead to over-consolidation, while rapid thawing can generate high pore pressures and compromise stability. Importantly, FT acts as a weathering mechanism, influencing soil properties at both the microscopic and macroscopic scales. These cycles can loosen over-consolidated soil, densify normally consolidated soil, and increase overall hydraulic conductivity due to structural changes. They can also weaken the soil’s structure and deteriorate its mechanical performance. Full article
Show Figures

Graphical abstract

20 pages, 8507 KB  
Article
FEA-Based Stress–Strain Barometers as Forecasters for Corneal Refractive Power Change in Orthokeratology
by Lo-Yu Wu, Wen-Pin Lin, Richard Wu, Lynn White and Ahmed Abass
Bioengineering 2024, 11(2), 166; https://doi.org/10.3390/bioengineering11020166 - 9 Feb 2024
Cited by 9 | Viewed by 2821
Abstract
Purpose: To improve the effectivity of patient-specific finite element analysis (FEA) to predict refractive power change (RPC) in rigid Ortho-K contact lens fitting. Novel eyelid boundary detection is introduced to the FEA model to better model the effects of the lid on lens [...] Read more.
Purpose: To improve the effectivity of patient-specific finite element analysis (FEA) to predict refractive power change (RPC) in rigid Ortho-K contact lens fitting. Novel eyelid boundary detection is introduced to the FEA model to better model the effects of the lid on lens performance, and stress and strain outcomes are investigated to identify the most effective FEA components to use in modelling. Methods: The current study utilises fully anonymised records of 249 eyes, 132 right eyes, and 117 left eyes from subjects aged 14.1 ± 4.0 years on average (range 9 to 38 years), which were selected for secondary analysis processing. A set of custom-built MATLAB codes was built to automate the process from reading Medmont E300 height and distance files to processing and displaying FEA stress and strain outcomes. Measurements from before and after contact lens wear were handled to obtain the corneal surface change in shape and power. Tangential refractive power maps were constructed from which changes in refractive power pre- and post-Ortho-K wear were determined as the refractive power change (RPC). A total of 249 patient-specific FEA with innovative eyelid boundary detection and 3D construction analyses were automatically built and run for every anterior eye and lens combination while the lens was located in its clinically detected position. Maps of four stress components: contact pressure, Mises stress, pressure, and maximum principal stress were created in addition to maximum principal logarithmic strain maps. Stress and strain components were compared to the clinical RPC maps using the two-dimensional (2D) normalised cross-correlation and structural similarity (SSIM) index measure. Results: On the one hand, the maximum principal logarithmic strain recorded the highest moderate 2D cross-correlation area of 8.6 ± 10.3%, and contact pressure recorded the lowest area of 6.6 ± 9%. Mises stress recorded the second highest moderate 2D cross-correlation area with 8.3 ± 10.4%. On the other hand, when the SSIM index was used to compare the areas that were most similar to the clinical RPC, maximum principal stress was the most similar, with an average strong similarity percentage area of 26.5 ± 3.3%, and contact pressure was the least strong similarity area of 10.3 ± 7.3%. Regarding the moderate similarity areas, all components were recorded at around 34.4% similarity area except the contact pressure, which was down to 32.7 ± 5.8%. Conclusions: FEA is an increasingly effective tool in being able to predict the refractive outcome of Ortho-K treatment. Its accuracy depends on identifying which clinical and modelling metrics contribute to the most accurate prediction of RPC with minimal ocular complications. In terms of clinical metrics, age, Intra-ocular pressure (IOP), central corneal thickness (CCT), surface topography, lens decentration and the 3D eyelid effect are all important for effective modelling. In terms of FEA components, maximum principal stress was found to be the best FEA barometer that can be used to predict the performance of Ortho-K lenses. In contrast, contact pressure provided the worst stress performance. In terms of strain, the maximum principal logarithmic strain was an effective strain barometer. Full article
Show Figures

Graphical abstract

16 pages, 4482 KB  
Article
Determination of Save Excavation Criteria in Velenje Coal Mine
by Željko Vukelić and Jurij Šporin
Minerals 2024, 14(1), 77; https://doi.org/10.3390/min14010077 - 9 Jan 2024
Cited by 1 | Viewed by 1627
Abstract
Ensuring safe conditions for mining coal under water-bearing sands in the Velenje coal mine depends on the designed parameters of hydrogeology, geomechanics and drainage. The purpose of the research is to predict and simulate the hydrostatic pressures above the excavation fields in order [...] Read more.
Ensuring safe conditions for mining coal under water-bearing sands in the Velenje coal mine depends on the designed parameters of hydrogeology, geomechanics and drainage. The purpose of the research is to predict and simulate the hydrostatic pressures above the excavation fields in order to determine the thickness of the insulation layers and the height of the excavation. Coal occurs in the Velenje basin in the form of a slightly concave lens. Directly above the coal seam is an insulating layer of marl or clay. Above the insulating layer are more or less permeable Pliocene sands in which water can accumulate under layer pressure, posing a potential risk of water ingress into underground spaces. In addition to the Pliocene sands, triad layers of different ages and lithology in the bedrock also pose a risk of water intrusion. In order to prevent the intrusion of water into the working areas of underground objects, the criteria for safe mining in the Velenje coal mine under aquifers were established. The scientific research approach to determining the criteria for safe mining enables the safety and determination of excavation heights in coal mining. The following data are required for such a calculation: the water pressure in the first sands, the excavation depth below the surface, the thickness of the insulating layer and the method of excavation or the course of the demolition processes. Full article
Show Figures

Figure 1

23 pages, 7793 KB  
Article
Application of the NSGA-II Algorithm and Kriging Model to Optimise the Process Parameters for the Improvement of the Quality of Fresnel Lenses
by Hanjui Chang, Yue Sun, Rui Wang and Shuzhou Lu
Polymers 2023, 15(16), 3403; https://doi.org/10.3390/polym15163403 - 14 Aug 2023
Cited by 7 | Viewed by 2394
Abstract
The Fresnel lens is an optical system consisting of a series of concentric diamond grooves. One surface of the lens is smooth, while the other is engraved with concentric circles of increasing size. Optical interference, diffraction, and sensitivity to the angle of incidence [...] Read more.
The Fresnel lens is an optical system consisting of a series of concentric diamond grooves. One surface of the lens is smooth, while the other is engraved with concentric circles of increasing size. Optical interference, diffraction, and sensitivity to the angle of incidence are used to design the microstructure on the lens surface. The imaging of the optical surface depends on its curvature. By reducing the thickness of the lens, light can still be focused at the same focal point as with a thicker lens. Previously, lenses, including Fresnel lenses, were made of glass due to material limitations. However, the traditional grinding and polishing methods for making Fresnel lenses were not only time-consuming, but also labour-intensive. As a result, costs were high. Later, a thermal pressing process using metal moulds was invented. However, the high surface tension of glass caused some detailed parts to be deformed during the pressing process, resulting in unsatisfactory Fresnel lens performance. In addition, the complex manufacturing process and unstable processing accuracy hindered mass production. This resulted in high prices and limited applications for Fresnel lenses. These factors prevented the widespread use of early Fresnel lenses. In contrast, polymer materials offer advantages, such as low density, light weight, high strength-to-weight ratios, and corrosion resistance. They are also cost effective and available in a wide range of grades. Polymer materials have gradually replaced optical glass and other materials in the manufacture of micro-optical lenses and other miniaturised devices. Therefore, this study focuses on investigating the manufacturing parameters of Fresnel lenses in the injection moulding process. We compare the quality of products obtained by two-stage injection moulding, injection compression moulding, and IMD (in-mould decoration) techniques. The results show that the optimal method is IMD, which reduces the nodal displacement on the Fresnel lens surface and improves the transmission performance. To achieve this, we first establish a Kriging model to correlate the process parameters with optimisation objectives, mapping the design parameters and optimisation objectives. Based on the Kriging model, we integrate the NSGA-II algorithm with the predictive model to obtain the Pareto optimal solutions. By analysing the Pareto frontier, we identify the best process parameters. Finally, it is determined that the average nodal displacement on the Fresnel surface is 0.393 mm, at a holding pressure of 320.35 MPa and a melt temperature of 251.40 °C. Combined with IMD technology, product testing shows a transmittance of 95.43% and an optimisation rate of 59.64%. Full article
(This article belongs to the Special Issue Advances in Polymers Processing and Injection Molding)
Show Figures

Figure 1

12 pages, 2337 KB  
Article
Polyacrylic Acid Hydrogel Coating for Underwater Adhesion: Preparation and Characterization
by Junjie Liu, Nan Hu, Yao Xie, Peng Wang, Jingxiang Chen and Qianhua Kan
Gels 2023, 9(8), 616; https://doi.org/10.3390/gels9080616 - 29 Jul 2023
Cited by 9 | Viewed by 3990
Abstract
Underwater adhesion involves bonding substrates in aqueous environments or wet surfaces, with applications in wound dressing, underwater repairs, and underwater soft robotics. In this study, we investigate the underwater adhesion properties of a polyacrylic acid hydrogel coated substrate. The underwater adhesion is facilitated [...] Read more.
Underwater adhesion involves bonding substrates in aqueous environments or wet surfaces, with applications in wound dressing, underwater repairs, and underwater soft robotics. In this study, we investigate the underwater adhesion properties of a polyacrylic acid hydrogel coated substrate. The underwater adhesion is facilitated through hydrogen bonds formed at the interface. Our experimental results, obtained through probe-pull tests, demonstrate that the underwater adhesion is rapid and remains unaffected by contact pressure and pH levels ranging from 2.5 to 7.0. However, it shows a slight increase with a larger adhesion area. Additionally, we simulate the debonding process and observe that the high-stress region originates from the outermost bonding region and propagates towards the center, spanning the thickness of the target substrate. Furthermore, we showcase the potential of using the underwater adhesive hydrogel coating to achieve in-situ underwater bonding between a flexible electronic demonstration device and a hydrogel contact lens. This work highlights the advantages of employing hydrogel coatings in underwater adhesion applications and serves as inspiration for the advancement of underwater adhesive hydrogel coatings capable of interacting with a wide range of substrates through diverse chemical and physical interactions at the interface. Full article
(This article belongs to the Special Issue Synthesis and Applications of Hydrogels)
Show Figures

Figure 1

17 pages, 4836 KB  
Article
Modulation of Membrane Trafficking of AQP5 in the Lens in Response to Changes in Zonular Tension Is Mediated by the Mechanosensitive Channel TRPV1
by Rosica S. Petrova, Nikhil Nair, Nandini Bavana, Yadi Chen, Kevin L. Schey and Paul J. Donaldson
Int. J. Mol. Sci. 2023, 24(10), 9080; https://doi.org/10.3390/ijms24109080 - 22 May 2023
Cited by 8 | Viewed by 2307
Abstract
In mice, the contraction of the ciliary muscle via the administration of pilocarpine reduces the zonular tension applied to the lens and activates the TRPV1-mediated arm of a dual feedback system that regulates the lens’ hydrostatic pressure gradient. In the rat lens, this [...] Read more.
In mice, the contraction of the ciliary muscle via the administration of pilocarpine reduces the zonular tension applied to the lens and activates the TRPV1-mediated arm of a dual feedback system that regulates the lens’ hydrostatic pressure gradient. In the rat lens, this pilocarpine-induced reduction in zonular tension also causes the water channel AQP5 to be removed from the membranes of fiber cells located in the anterior influx and equatorial efflux zones. Here, we determined whether this pilocarpine-induced membrane trafficking of AQP5 is also regulated by the activation of TRPV1. Using microelectrode-based methods to measure surface pressure, we found that pilocarpine also increased pressure in the rat lenses via the activation of TRPV1, while pilocarpine-induced removal of AQP5 from the membrane observed using immunolabelling was abolished by pre-incubation of the lenses with a TRPV1 inhibitor. In contrast, mimicking the actions of pilocarpine by blocking TRPV4 and then activating TRPV1 resulted in sustained increase in pressure and the removal of AQP5 from the anterior influx and equatorial efflux zones. These results show that the removal of AQP5 in response to a decrease in zonular tension is mediated by TRPV1 and suggest that regional changes to PH2O contribute to lens hydrostatic pressure gradient regulation. Full article
(This article belongs to the Special Issue Aquaporins: Dynamic Role and Regulations)
Show Figures

Figure 1

11 pages, 1936 KB  
Article
Optic Fiber Microsensor Reveals Specific Spatiotemporal Oxygen Uptake Profiles at the Mammalian Ocular Surface
by Qin Sun, Li Ma, Fernando Ferreira, Chelsea Brown, Brian Reid and Min Zhao
Biosensors 2023, 13(2), 245; https://doi.org/10.3390/bios13020245 - 9 Feb 2023
Cited by 3 | Viewed by 2396
Abstract
Oxygen (O2) uptake by cells and tissues is a critical indicator of metabolic demand, changes in microenvironment, and pathophysiology. O2 uptake from the atmosphere accounts for virtually all the O2 consumption in the avascular cornea; however, a detailed spatiotemporal [...] Read more.
Oxygen (O2) uptake by cells and tissues is a critical indicator of metabolic demand, changes in microenvironment, and pathophysiology. O2 uptake from the atmosphere accounts for virtually all the O2 consumption in the avascular cornea; however, a detailed spatiotemporal profile of corneal O2 uptake (COU) remains undetermined. Here, we used a non-invasive self-referencing optical fiber O2 sensor—the scanning micro-optrode technique (SMOT)—to report the O2 partial pressure and flux variations at the ocular surface of rodents and non-human primates. In vivo spatial mapping in mice revealed a distinct COU, characterized by a centripetal gradient with a significantly higher O2 influx at the limbus and conjunctiva regions than at the center of the cornea. This regional COU profile was reproduced ex vivo in freshly enucleated eyes. The centripetal gradient was conserved across the following species analyzed: mice, rats, and rhesus monkeys. In vivo temporal mapping in mice showed a significant increase in the O2 flux in the limbus in the evening compared to other times. Altogether, the data unveiled a conserved centripetal COU profile, which may be associated with the limbal epithelial stem cells residing at the intersection of the limbus and conjunctiva. These physiological observations will serve as a useful baseline for comparative studies with contact lens wear, ocular disease, diabetes, etc. Moreover, the sensor may be applied to understand the responses of the cornea and other tissues to various insults, drugs, or changes in the environment. Full article
(This article belongs to the Special Issue Optical Fiber Sensors for Biomedical Application)
Show Figures

Figure 1

18 pages, 3932 KB  
Article
Multi-Objective Optimization of Liquid Silica Array Lenses Based on Latin Hypercube Sampling and Constrained Generative Inverse Design Networks
by Hanjui Chang, Shuzhou Lu, Yue Sun, Guangyi Zhang and Longshi Rao
Polymers 2023, 15(3), 499; https://doi.org/10.3390/polym15030499 - 18 Jan 2023
Cited by 17 | Viewed by 2845
Abstract
Injection molding process parameters have a great impact on plastic production quality, manufacturing cost, and molding efficiency. This study proposes to apply the method of Latin hypercube sampling, and to combine the response surface model and “Constraint Generation Inverse Design Network (CGIDN)” to [...] Read more.
Injection molding process parameters have a great impact on plastic production quality, manufacturing cost, and molding efficiency. This study proposes to apply the method of Latin hypercube sampling, and to combine the response surface model and “Constraint Generation Inverse Design Network (CGIDN)” to achieve multi-objective optimization of the injection process, shorten the time to find the optimal process parameters, and improve the production efficiency of plastic parts. Taking the LSR lens array of automotive LED lights as the research object, the residual stress and volume shrinkage were taken as the optimization objectives, and the filling time, melt temperature, maturation time, and maturation pressure were taken as the influencing factors to obtain the optimization target values, and the response surface models between the volume shrinkage rate and the influencing factors were established. Based on the “Constraint-Generated Inverse Design Network”, the optimization was independently sought within the set parameters to obtain the optimal combination of process parameters to meet the injection molding quality of plastic parts. The results showed that the optimal residual stress value and volume shrinkage rate were 11.96 MPa and 4.88%, respectively, in the data set of 20 Latin test samples obtained based on Latin hypercube sampling, and the optimal residual stress value and volume shrinkage rate were 8.47 MPa and 2.83%, respectively, after optimization by the CGIDN method. The optimal process parameters obtained by CGIDN optimization were a melt temperature of 30 °C, filling time of 2.5 s, maturation pressure of 40 MPa, and maturation time of 15 s. The optimization results were obvious and showed the feasibility of the data-driven injection molding process optimization method based on the combination of Latin hypercube sampling and CGIDN. Full article
(This article belongs to the Special Issue Multifunctional Polymer Molding Processing of Polymers)
Show Figures

Figure 1

15 pages, 1460 KB  
Article
Diagnosing the Institutional Forces Impacting Australia’s Aerial Firefighting Capability
by Maddison Seeley, Hamish Hede, Mitchell Bylart and John Rodwell
Sustainability 2023, 15(2), 1636; https://doi.org/10.3390/su15021636 - 14 Jan 2023
Cited by 1 | Viewed by 2331
Abstract
Climate change is resulting in more wildfires, and increasingly, there are overlapping wildfire seasons between the northern and southern hemispheres. The changing climate is especially impacting the nature of aerial firefighting. This study uses an institutional lens to analyse the resources and structures [...] Read more.
Climate change is resulting in more wildfires, and increasingly, there are overlapping wildfire seasons between the northern and southern hemispheres. The changing climate is especially impacting the nature of aerial firefighting. This study uses an institutional lens to analyse the resources and structures associated with aerial firefighting in Australia. A set of convergent interviews of subject matter experts surfaced the key issues that have led to the current aerial firefighting situation in Australia and showed the relationships between issues. The convergent interviewing method is used to identify the core, common issues that influence the aerial firefighting system in Australia. The results highlight how aerial firefighting suffers due to the complexities that exist between the states and from a lack of a national strategy. A lack of process standardisation, an overreliance on, often international, LATs and the lack of a coordinated mitigation approach are particularly notable specific issues. Institutional theory suggests that Australia’s aerial firefighting capability has succumbed to isomorphic pressures, with the desire for legitimacy driving ever-increasing institutionalization. To respond to the changing environment, institutional entrepreneurs will be needed to create new norms and significantly change the embedded structures. Full article
(This article belongs to the Special Issue Innovative Technologies for Sustainable Fire Suppression Systems)
Show Figures

Figure 1

Back to TopTop