Search Results (8,602)

In this work we investigate the integration possibility of a thermistor paste from ESL (ElectroScience Laboratory, now Vibrantz) to see if it is adapted for Vibrantz Low Temperature Cofired Ceramics (LTCC) L8 and A6M-E materials. An alumina-based sample is used as a reference circuit throughout this study. Square, two-squares-in-parallel and two-squares-in-series thermistors are tested, placed internally and externally. Resistive values are measured in a range from 25 °C to 300 °C. The variation in the resistive values among similar thermistors is significant, with a maximum standard deviation of 67%. However, in all cases, there is a positive linear relationship between resistance and temperature. The Temperature Coefficient of Resistance (TCR) value is calculated before and after annealing. In general, the L8 and Al₂O₃ samples exhibit higher TCR values than the A6M-E sample. Additionally, when placed internally, the TCR value decreases approximately 30% for both tested LTCC materials. An Energy-Dispersive X-ray Spectroscopy (EDX) material analysis has also been conducted on the samples, revealing that the main chemical components are oxide, silicon, calcium, and ruthenium but also some barium and titanium, which indicates SiO₂, TiO₂, BaTiO₃ and RuO₂ oxides in the thermistor paste. The possibility to implement thermistors internally and externally on Vibrantz LTCC without delamination problems is endorsed by this study. Full article

This study investigates the Enzyme Biofilm Method (EBM), a biological wastewater treatment technology previously developed by the authors. EBM employs microbial-derived hydrolytic enzyme groups in the initial treatment stage to break down high-molecular-weight organic matter—such as starch, proteins, and fats—into low-molecular-weight compounds. These compounds enhance the growth of native microorganisms, promoting biofilm formation on carriers and improving treatment efficiency. Over the past decade, EBM has been practically applied in food factory wastewater facilities handling high organic loads. The enzyme groups used in EBM are derived from cultures of Bacillus mojavensis, Saccharomyces cariocanus, and Lacticaseibacillus paracasei. To clarify the system’s mechanism and ensure its practical viability, this study focused on starch—a prevalent and recalcitrant component of food wastewater—using two evaluation approaches. Verification 1: Field testing at a starch factory showed that adding enzyme groups to the equalization tank effectively reduced biological oxygen demand (BOD) through starch degradation. Verification 2: Laboratory experiments confirmed that the enzyme groups possess both amylase and maltase activities, sequentially breaking down starch into glucose. The resulting glucose supports microbial growth, facilitating biofilm formation and BOD reduction. These findings confirm EBM’s potential as a sustainable and effective solution for treating high-strength food industry wastewater. Full article

As coal mining progresses to greater depths, the complex geological conditions significantly increase the risk of compound disasters. With increasing mining depth, elevated ground stress and gas pressure exacerbate the coupling effects of rockburst and gas outburst. This study employs laboratory tests and theoretical analysis to investigate gas disasters under varying gas and confining pressures. The experimental results are analyzed in terms of mechanical parameters, crack propagation, and acoustic emission (AE) time–frequency evolution. Under conventional compression, coal failure exhibits shear damage with axial splitting or debris ejection. The peak strength demonstrates a clear confining pressure strengthening effect and gas pressure weakening effect. At constant gas pressure, the elastic modulus increases with confining pressure, whereas at constant confining pressure, it decreases with rising gas pressure. Full article

Introduction: Borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a rare and poorly characterized phenotype of S. aureus. Its detection remains challenging, even in modern clinical laboratories. Moreover, there is no consensus on the optimal therapeutic approach, and treatment strategies remain controversial. In this report, we present a rare case of BORSA bacteremia and discuss potential approaches to improve its detection and management. Case presentation: A 39-year-old woman with systemic lupus erythematosus was admitted for a suspected exacerbation, complicated by multiple serositis and nephritis. She was on chronic treatment with methylprednisolone and hydroxychloroquine. On admission, she was afebrile. Laboratory investigations revealed elevated C-reactive protein and increased D-dimer levels. Later, she developed a septic peripheral venous thrombophlebitis, and treatment was adjusted to amoxicillin–clavulanate. Blood cultures grew S. aureus, prompting a switch to intravenous oxacillin based on a negative penicillin-binding protein 2a test. A discrepancy in the antimicrobial susceptibility test was observed, with cefoxitin showing susceptibility and oxacillin resistance. Further characterizations were carried out, confirming a BORSA infection. Treatment was switched to linezolid and ciprofloxacin with good recovery. Conclusions: This case highlights the complexity of managing a patient with an uncommon and poorly documented infection. The lack of data on BORSA infections and the difficulties in detecting and treating them led to a prolonged delay in the appropriate management of this patient. Full article

Background: Type 2 diabetes mellitus (T2DM) increases sepsis risk due to immune dysfunction and chronic inflammation. Antidiabetic medications, while primarily used for glycemic control, may modulate sepsis susceptibility through immune and inflammatory pathways. This study investigates the association between antidiabetic medication use and sepsis risk in T2DM patients. Methods: A longitudinal cohort study was conducted using clinical registry data from 5009 T2DM patients at the University Hospital, Debrecen, Hungary (2016–2020). Sepsis cases were identified via ICD-10 code A41, and antidiabetic medication use was categorized using ATC codes. Baseline comorbidities and laboratory parameters were extracted. Chi-square and Wilcoxon rank–sum tests assessed associations between sepsis and categorical/numerical variables, respectively. Time-adjusted multivariate logistic regression evaluated predictors of sepsis risk, with odds ratios (ORs) and 95% confidence intervals (CIs) reported. Results: Age, hypertension, ischemic heart disease, nephropathy, elevated blood glucose, C-reactive protein, and creatinine also independently increased sepsis risk. Insulin use was associated with a 2.6-fold increased sepsis risk (OR = 2.6, 95% CI: 2.09–3.34, p < 0.001), while SGLT2 inhibitors (OR = 0.56, 95% CI: 0.34–0.91, p = 0.02) and GLP-1 receptor agonists (OR = 0.39, 95% CI: 0.19–0.79, p = 0.009) were protective. Conclusions: Insulin-treated patients may require closer infection monitoring, while SGLT2 inhibitors and GLP-1 RAs could be prioritized in high-risk individuals. These findings highlight the potential to inform risk stratification and guide personalized antidiabetic therapy to reduce sepsis risk in T2DM. Full article

To address the complex pile–soil interaction mechanisms in predicting the compressive bearing capacity of HSCM piles (Helix Stiffened Cement Mixing piles) in marine soft soil regions, this study proposes an intelligent prediction method based on a GA-BPNN (Genetic Algorithm-Optimized Back Propagation Neural Network). A high-quality database comprising 1243 data points was established through finite element numerical simulations. By integrating data preprocessing techniques and the GA-BPNN model, the study systematically investigated the influence of helical blade spacing H₁ and H₂, strength ratio C_ref/S_u, and diameter ratio D_sc/D_H on bearing capacity. The results demonstrate that the GA-BPNN model achieves a prediction accuracy of 99.07%, with a mean squared error (MSE) of 7.20 × 10⁻³ and a coefficient of determination R² of 0.990. SHAP value analysis reveals that the strength ratio and diameter ratio are the dominant factors, exhibiting nonlinear relationships with bearing capacity characterized by saturation effects and threshold-dependent behavior. Laboratory tests further confirm strong correlations between cement–soil strength C_ref, formed pile diameter D_sc, and bearing capacity. The findings indicate that the GA-BPNN model provides an efficient and accurate approach for predicting the bearing capacity of HSCM piles, offering a reliable basis for engineering parameter optimization. Full article

Background and Clinical Significance: Obstructive sleep apnea (OSA) is a common comorbidity in patients with cardiac and metabolic disorders. The coexistence of central sleep apnea with Cheyne–Stokes breathing (CSA-CSB) in heart failure patients, especially those with preserved ejection fraction (HFpEF), represents a diagnostic and therapeutic challenge. Data on continuous positive airway pressure (CPAP) failure and successful adaptation to servo-ventilation (ASV) in the context of complex comorbidities remain limited. Case Presentation: We present the case of a 74-year-old male with a history of type 2 diabetes mellitus, paroxysmal atrial fibrillation, HFpEF, essential hypertension, and bladder carcinoma. He was referred for pre-operative OSA screening, reporting excessive daytime sleepiness, insomnia, and witnessed apneas. Initial respiratory polygraphy revealed severe sleep-disordered breathing with dominant CSA-CSB and moderate OSA. Laboratory investigations also revealed severe iron-deficiency anemia, which was managed with parenteral iron supplementation. The patient underwent CPAP titration, which led to modest improvement and residual high apnea–hypopnea index (AHI). After persistent symptoms and an inadequate CPAP response, an ASV device was initiated with significant clinical and respiratory improvement, demonstrating normalization of hypoxic burden and optimal adherence. Conclusions: CSA-CSB in HFpEF patients with anemia poses unique therapeutic difficulties. This case highlights the importance of individualized diagnostic and therapeutic strategies, including transitioning to ASV in CPAP-refractory cases, which can lead to improved adherence, reduced hypoxia, and better overall outcomes in high-risk patients. Full article

This study aims to investigate the differences in the effects of spraying and immersing methods on edible coatings for halved and pitted plums. Earlier studies have shown that these biodegradable packaging materials can preserve the quality and safety of fruits for an extended shelf life. Halved and pitted plums (variety Stanley) were treated with chitosan and rosehip oil edible coating emulsions by spraying and immersing methods. The treated series were analyzed by physical, physicochemical, microbiological, and sensorial methods during refrigerated storage for nine days, until the onset of microbiological spoilage. At the beginning of the storage, there was a visible difference between the differently treated samples. The untreated series showed the fastest browning. The emulsion-sprayed samples presented the least changes in color, shape, and volume. A weaker effect of the immersion technique can be explained by a deep standing of the fruits in a treating solution or emulsion. Some of the immersed samples have an aqueous texture and received a smaller sensory rating. The advantages and disadvantages of the methods need further investigation, but on a production scale, spraying can guarantee uniform batches. In laboratory circumstances, immersion is an easier method that does not need expensive and difficult-to-use equipment and gives good results. Full article

This study investigates personal exposure to fine particulate matter (PM_2.5) during walking commutes in Gliwice, Poland—a city characterized by elevated levels of air pollution. Data from a low-cost air quality sensor were compared with a municipal monitoring station and the Silesian University of Technology laboratory. PM_2.5 concentrations recorded by the low-cost sensor (7.3 µg/m³) were lower than those reported by the stationary monitoring sites. The findings suggest that low-cost sensors may offer valuable insights into short-term peaks in PM_2.5 exposure to serve as a practical tool for increasing public awareness of personal exposure risks to protect respiratory health. Full article

Urban forests are vital to cities because they provide a range of ecosystem services, including carbon (C) sequestration, air purification, and urban cooling. However, urban forestry also generates significant amounts of organic waste, such as grass clippings, pruned tree branches, and fallen tree leaves and woody debris that can contribute to greenhouse gas (GHG) emissions if not properly managed. In this study, we investigated the effect of wheat straw biochar (produced at 500 °C) on GHG emissions from two types of urban forestry waste: green waste (GW) and yard waste (YW), using a 100-day laboratory incubation experiment. Overall, GW released more CO₂ than YW, but biochar addition reduced cumulative CO₂ emissions by 9.8% in GW and by 17.6% in YW. However, biochar increased CH₄ emissions from GW and reduced the CH₄ sink strength of YW. Biochar also had contrasting effects on N₂O emissions, increasing them by 94.3% in GW but decreasing them by 61.4% in YW. Consequently, the highest global warming potential was observed in biochar-amended GW (125.3 g CO₂-eq kg⁻¹). Our findings emphasize that the effect of biochar on GHG emissions varies with waste type and suggest that selecting appropriate biochar types is critical for mitigating GHG emissions from urban forestry waste. Full article

This study aims to overcome the limitations of conventional plunge tests for evaluating resistance temperature detector (RTD) response times under actual operating conditions, particularly in confined nuclear power plant piping. An in situ measurement device based on the loop current step response (LCSR) method was developed, with a conversion relationship to plunge test results established through numerical simulation and experimental validation. Investigations in a rotating water channel (over the flow velocity range of 0.2 to 0.6) confirmed excellent agreement in RTD response time, showing only 3.78% deviation between second-order-converted LCSR and plunge test measurements at 0.6 m/s. Both methods consistently revealed reduced RTD response times at higher flow velocities, with deviations consistently within ±10%, complying with nuclear instrumentation standards (NB/T 20069-2012). The LCSR method enables reliable in situ assessment while maintaining strong correlation with laboratory plunge tests. Full article

Background and Objectives: The uric acid to HDL-cholesterol ratio (UHR) has recently emerged as a promising biomarker reflecting systemic inflammation and metabolic disturbances. Elevated liver transaminases are clinical indicators of hepatic injury and underlying metabolic dysfunction. Many Middle Eastern countries face constrained clinical and laboratory resources, where access to comprehensive diagnostic tools may be limited. In such settings, identifying simple and easily accessible markers could offer significant practical value in detecting and monitoring health disorders. This study investigates the potential association between UHR and elevated liver transaminases levels in the Saudi general population. Materials and Methods: This retrospective cross-sectional study included 9618 subjects, and the association between the UHR and elevated liver transaminases, alanine transaminase (ALT), and aspartate transaminase (AST), was comprehensively analysed. In addition, the study assessed risk indicators including the prevalence ratio (PR) and odds ratio (OR) as well as the diagnostic accuracy of UHR and C-reactive protein (CRP) in detecting liver transaminases abnormalities, with analyses stratified by age and gender. Results: UHR was significantly elevated in subjects with increased ALT and AST activities, and this pattern was consistent across all age and gender categories. High UHR was significantly associated with elevated ALT (OR = 2.32, 95% CI: 2.12–2.53, p < 0.001) and AST (OR = 1.38, 95% CI: 1.25–1.52, p < 0.001), with stronger associations observed in males and for ALT activity. In addition, elevated UHR was more prevalent among individuals with increased liver transaminase activities. Receiver operating characteristic (ROC) analysis showed that UHR outperformed CRP in identifying elevated liver transaminases, with better discriminative ability for ALT than AST activity. Conclusions: These findings highlight a significant association between UHR and liver transaminase abnormalities in the general population, underscoring the potential utility of UHR as a simple and accessible indicator for liver function assessment in clinical settings. Full article

Although cemented carbides have been manufactured by the powder metallurgy (P/M) technology for over a century now, systematic developmental efforts are still underway. In the present study, tool life improvements in metal grooving applications are the key objective. Four PVD-coated cemented carbides compositions, dedicated to groove steel, stainless steel, cast iron, and aluminium alloys, have been newly designed, along with their manufacturing conditions. Physical, mechanical and chemical characteristics—such as sintered density, modulus of elasticity, hardness, fracture toughness, WC grain size, and the chemical composition of the substrate material, as well as the chemical composition, microhardness, structure, and thickness of the coatings—have been studied. A series of grooving tests have also been conducted to assess whether modifications to the thus far marketed tool materials, tool geometries, and coatings can improve cutting performance. In order to compare the laboratory and application properties of the investigated materials with currently produced by reputable companies, commercial inserts have also been tested. The experimental results obtained indicate that the newly developed grooving inserts exhibit excellent microstructural characteristics, high hardness, fracture toughness, and wear resistance and that they show slightly longer tool life compared to the commercial ones. Full article

As a typical porous medium, unsaturated loess demonstrates critical hydro-mechanical coupling properties that fundamentally influence geohazard mitigation, groundwater resource evaluation, and foundation stability in geotechnical engineering. This investigation develops a novel theoretical framework to overcome the limitations of existing models in converting electrical resistivity tomography (ERT) profiles into water content distributions for unsaturated loess through quantitative inversion modeling. Systematic laboratory investigations on remolded loess specimens with controlled density and water content conditions revealed distinct resistivity–water interaction mechanisms. A characteristic two-stage decay pattern was identified: resistivity exhibited an exponential decrease from 420 Ω·m (water saturation (S_w = 10%)) to 90 Ω·m (S_w = 40%), followed by asymptotic stabilization at S_w ≥ 40%. The derived quantitative correlation provides a robust mathematical basis for water content profile inversion. Field validation through integrated ERT and borehole data demonstrated exceptional predictive accuracy in shallow strata (<20 m depth), achieving mean absolute errors of <5%. However, inversion reliability decreased with depth (>20 m), primarily attributed to density-dependent charge transport mechanisms. This underscores the necessity of incorporating coupled thermo-hydro-mechanical processes for deep-layer characterization. This study provides a robust framework for engineering applications of ERT in loess terrains, offering significant advancements in geotechnical monitoring and geohazard prevention. Full article

The aim of this research was to develop a lightweight armor that could be used in bulletproof vests or vehicle protection, offering an alternative to the disadvantageous properties of high-strength steel plates. Specifically, the study focused on investigating the properties of different binders to identify the most suitable one for further development. The bulletproof characteristics of Kevlar (aramid) fiber fabric (200 g/m², plain weave, CT709) were examined using both the Ansys simulation environment and ballistic laboratory testing. In the experiments, three different layer configurations were tested on 300 × 300 mm specimens, each consisting of 20 layers of Kevlar. The layers were arranged as follows: dry lamination for the first specimen, epoxy binder for the second, and polyurethane binder for the third. Laboratory tests were conducted using 9 mm Parabellum bullets, in accordance with the parameters defined in the MSZ K 1114-1:1999 standard. Both the ballistic and simulation tests indicated that the Kevlar laminated with polyurethane resin demonstrated the most promising performance and is suitable for further development. Full article