Search Results (62)

There have been reports of an association between the gut microbiota and the development of chronic liver disease, fibrosis, and carcinogenesis; however, it is not yet possible to reach a definite conclusion. In this cross-sectional study, we examined the association between the presence or absence of hepatocellular carcinoma (HCC) and the gut microbiota in patients with chronic hepatitis B virus (HBV) infection. The study subjects consisted of 62 consecutive HBV patients admitted to our hospital who provided informed consent to participate in the study. We performed 16S rRNA analysis using DNA extracted from fecal pellets. The sequencing depth per sample was 80,000 to 90,000 reads. We calculated the proportion of each bacterial genus so that the total for each sample added up to 100%. The male-to-female ratio was 49/13, the median age was 67 years, and 46 of the patients had HCC. Twenty microbial phyla spanning 41 classes, 79 orders, 163 families, and 431 genera were identified. Receiver operating characteristic (ROC) analysis was performed on the identified bacterial taxa, from the level of phylum down to genus, to assess their ability to distinguish between patients with and without HCC. Several bacteria with an area under the curve (AUC) > 0.65 were identified as follows: TM7 phylum TM7-3 class (AUC = 0.700); Firmicutes phylum Clostridiales class Lachnobacterium genus, Dialister genus, Ruminococcus genus, and Roseburia genus (AUC = 0.670, 0.668, 0.667, and 0.660, respectively); and Firmicutes phylum Erysipelotrichi class (AUC = 0.656). Combining three of these taxa resulted in high discriminative power (p = 0.000585) with a sensitivity and specificity of 0.761 and 0.750, respectively. A similar trend was observed in the subgroup analysis based on liver reserve capacity. Even after adjusting for factors related to liver reserve capacity in the multivariate analysis, an association between these bacterial genera and HCC was confirmed. Our results suggest that gut microbiota may be associated with the prevalence of HCC in HBV patients. Full article

The co-gasification of biomass and municipal solid waste (MSW) has high potential for sustainable energy generation and waste-to-energy applications. Calliandra calothyrsus (CC) and MSW pellets have complementary thermochemical properties, although there are few experimental studies on their co-gasification in downdraft reactors. This study analyzed the effect of the feedstock composition on the temperature distribution inside the reactor, the syngas composition, and the quality of syngas energy in a 1–2.5 kg/h downdraft gasifier during co-gasification. Six feedstock blend compositions were experimentally evaluated: they were 100 CC, 70 CC–30 MSW, 60 CC–40 MSW, 40 CC–60 MSW, 30 CC–70 MSW, and 100 MSW. The criteria considered for measuring include reactor temperature distribution, syngas composition (CO, H₂, CO₂, and C_nH_m), and lower heating value (LHV). The results indicated that the 70 CC–30 MSW blend had the best syngas performance with a higher oxidation-zone temperature, greater CO concentration, reasonably steady H₂ generation, lower C_nH_m concentration, and the highest syngas LHV compared to other feedstock compositions. In the gasification process, the increase in the proportion of CC was beneficial to char reactivity, oxidation–reduction reaction, and tar cracking. The increase in MSW fractions decreased syngas quality due to the increase in ash and moisture content. The results show that co-gasification of Calliandra calothyrsus and bio-dried MSW pellets can increase syngas quality and provide practical insight into the optimization of biomass–MSW blending for downdraft gasification systems. Full article

With the increasing depletion of high-quality iron ore resources, the efficient utilization of refractory ores has become a critical challenge in the iron and steel industry. This review systematically examines recent advances in sintering granulation technologies aimed at enhancing the processing of such ores. The study focuses on two main categories: conventional intensification methods, including moisture optimization, binder application, and mixer improvements, and novel sintering processes such as press-briquetting, pelletized sintering, split-stream granulation, composite agglomeration (CAP), and pre-granulation sintering. Key findings indicate that while conventional techniques can partially improve granulation uniformity and sintering bed permeability, they remain inadequate for handling high proportions of ultrafine ores or secondary iron-bearing materials. In contrast, innovative processes like CAP and pre-granulation sintering demonstrate superior adaptability and efficiency by integrating pelletizing and sintering mechanisms, enabling the treatment of complex ores and industrial residues. The adoption of advanced intensification-granulation sintering technologies offers a viable pathway toward sustainable ironmaking, providing the steel industry with essential tools to mitigate raw material constraints, lower production costs, and support green transformation. Future efforts should prioritize intelligent control, process integration, and the scaling of emerging techniques to maximize their industrial potential. Full article

Against the backdrop of global climate warming and energy shortages, China proposed the “dual-carbon strategy” in 2020 to address climate change and promote ecological civilization. As a high-carbon emission industry, the iron and steel sector faces an urgent need to accelerate low-carbon transformation. In 2024, China’s crude steel production accounted for over 50% of the total global crude steel production, with the blast furnace–basic oxygen furnace route remaining the dominant process. As a natural iron-bearing raw material, lump ore features high iron grade and low cost, eliminating the requirements of high-temperature processing steps such as sintering or pelletizing. Therefore, increasing the proportion of lump ore in the blast furnace burden represents an effective approach to achieving energy conservation and emission reduction. However, constrained by technical constraints, the current utilization rate of natural lump ore in Chinese steel enterprises remains generally low. Research indicates that despite their higher iron content, lump ores exhibit deficiencies in metallurgical properties such as thermal shock resistance and softening–melting drip characteristics, limiting their large-scale application. Therefore, it is typically necessary to perform pre-treatment such as preheating before charging into the furnace. In actual blast furnace burden design, it is essential to balance metallurgical performance and economic considerations by appropriately combining lump ore with high-basicity sinter and pellets. This approach leverages high-temperature interactions among the burden materials to optimize the overall softening and melting behavior of the mixed charge, thereby ensuring smooth furnace operation while simultaneously advancing the low-carbon transition of the iron and steel industry. Full article

The advancement of green and low-carbon transition in the steel industry has increased the demand for high-quality direct reduced iron (DRI) as a premium feedstock for electric arc furnace steelmaking. This imposes stricter quality requirements for fired pellets utilized in gas-based shaft furnace processes. To address the poor low-temperature reduction degradation (LTD) of fired pellets produced from a single high-grade magnetite concentrate during gas-based direct reduction. This study investigates the effects of blending hematite concentrates into a magnetite concentrate base (with additions of 0, 20 wt.%, 30 wt.%, and 40 wt.%) on the characteristics of the mixed concentrates, green ball properties, firing performance, and the metallurgical performance of the resulting fired pellets under conditions simulating an HYL shaft furnace. The results indicate that the incorporation of hematite concentrate optimizes the overall particle size distribution and green ball properties. As the hematite proportion increases, the optimal preheating temperature for green balls rises, while the required roasting temperature decreases. The most significant reduction in roasting temperature, from 1225 °C to 1175 °C, is achieved with a 20 wt.% hematite addition. Regarding metallurgical properties, the addition of hematite has a minor effect on the reducibility index (RI) but substantially improves the reduction swelling index (RSI). A notable decrease in the RSI is observed at addition levels of 30% and above. Critically, the LTD is significantly enhanced. The optimal improvement is attained with a 20 wt.% hematite blend, resulting in a- LTD_{+6.3 mm} fraction of 97.48 wt.%, a- LTD_{−3.2 mm} fraction of only 2.18 wt.%, and a whole pellet ratio of 88.01% after reduction. Considering the comprehensive performance, a blend of hematite concentrate between 20 wt.% and 30 wt.% yields fired pellets with superior characteristics, meeting the production requirements for gas-based shaft furnace direct reduction processes. This study provides an effective technological pathway for producing high-performance DRI-grade pellets from high-grade magnetite concentrates, contributing to the green and low-carbon transformation of the iron and steel industry. Full article

Almond hulls and shells are abundant by-products of the almond industry that could be valorized as bio-based absorbent polymers (BAP), offering a promising alternative to synthetic materials to improve water management in the agricultural setting. In this study, almond hulls and shells were pelletized in different proportions to assess pelletization feasibility and physical properties, followed by industrial-scale production of an industrialized formulation (80% hulls, 20% shells). Ecotoxicological risk was assessed using direct bioassays with whole pellets (germination with Lactuca sativa and Zea mays; acute toxicity with Eisenia fetida) and indirect bioassays with pellet water extracts (germination with L. sativa, immobilization with Daphnia magna, and bioluminescence inhibition with Vibrio fischeri). Field trials were conducted in an irrigated almond orchard to evaluate soil moisture dynamics and plant water status under different BAP application rates and irrigation regimes. Pelletization increased the soil’s water-holding capacity in the laboratory test and soil moisture in the field, even under reduced irrigation. However, ecotoxicological assays revealed significant to high acute toxicity at higher concentrations, depending on the organism and exposure pathway. Almond hull and shell pellets show potential to improve soil water retention and reduce irrigation demand but require cautious application and further testing to mitigate ecotoxicological risks. Full article

Neural progenitor cell (NPC) transplantation is a promising strategy for spinal cord injury repair, as graft-derived neurons can integrate into host circuitry and promote functional recovery. While the brain-regional and dorsoventral identities of NPCs are known to influence graft composition and performance, the importance of axial (rostrocaudal) identity, specifically whether NPCs must be matched to the spinal level of injury, remains poorly understood. To address this, we compared outcomes following transplantation of NPCs isolated from the anterior embryonic spinal cord (A-NPCs) versus the posterior spinal cord (P-NPCs) in a mouse model of C5 cervical dorsal column injury. Following transplantation, NPCs retained their intrinsic molecular axial identities; P-NPC grafts maintained significantly higher expression of the lumbar-associated gene HoxC10 and possessed a higher proportion of Chx10-high V2a neurons compared to A-NPCs. Despite these maintained molecular differences, A-NPC and P-NPC grafts were indistinguishable in neuronal and glial density, axon outgrowth, and their ability to support host axon regeneration, including the corticospinal tract. Long-term behavioral testing and retrograde transsynaptic tracing revealed no significant differences between groups in the recovery of skilled pellet reaching, grip strength, or synaptic integration with host cervical motor circuitry. These findings demonstrate that although transplanted NPCs retain their molecular axial identity in the adult injured environment, this identity is not a primary determinant of anatomical integration or functional outcome. Our findings suggest a degree of plasticity in graft-host interactions and indicate that strict segment-matching is not essential for the efficacy of NPC-based therapies in spinal cord injury. Full article

The growing demand for carbon-based energy materials requires sustainable alternatives to fossil fuels. This study explored the production and characterization of char obtained from refuse-derived fuel (RDF) and biomass blended pellets in varying proportions (0%, 15%, 25%, 50%, and 100% RDF). The objective was to evaluate their potential as high-energy-density solid fuels while addressing operational challenges related to ash behavior. Chars were produced at 400 °C for one hour in a muffle furnace in closed crucibles. A set of analytical techniques (calorimetry, infrared spectroscopy, thermogravimetry, inductively coupled plasma, and X-ray fluorescence) was employed to assess physicochemical properties. RDF content strongly affected mass yield, energy yield, and thermochemical behavior. Among the tested formulations, char with 50 and 25% of RDF (C_RDF50:BW50 and C_RDF25:BW75) ignited at lower temperatures (≈150 °C) and showed high flammability (C) values (1.97–2.03 × 10⁻⁵), indicating greater flammability. They also reached higher combustion temperatures (716–746 °C), suggesting improved thermal stability during the final combustion stage. Both chars presented increased high heating values (18–19 MJ/kg, dry basis) and a few surface functional groups. This supports a lower devolatilization rate, meaning that although ignition is easy, combustion remains stable and controllable. All chars showed very high acid–base indices, indicating a strong tendency for ash melting. However, low slag viscosity and alkalinity values suggest viscous, poorly mobile slag, reducing adhesion and buildup on reactor surfaces. This study combines thermogravimetric combustion analysis with ash chemistry–based slagging and fouling indices to provide an integrated assessment of the operational behavior of RDF–biomass-derived char fuels. The results highlight the technical feasibility of chars produced from RDF and biomass blended pellets, whose thermal properties make them promising candidates for use as solid fuels. Full article

The existing blast furnace burden structure in China is mainly dominated by high-alkalinity sinter and acid pellets, with a relatively small proportion of lump ore blended in. Against the backdrop of the “dual-carbon” goals, iron and steel plants are under enormous pressure to save energy and reduce carbon emissions. Lump ore is directly extracted from mines and belongs to zero-carbon-emission blast furnace burden. Therefore, adjusting and optimizing the blast furnace burden structure by partially replacing sinter and pellets with lump ore is an important approach for iron and steel plants to reduce carbon emissions. Based on the metallurgical properties and decrepitation index of different types of lump ore as well as the proportion of lump ore charged into the blast furnace, and with full consideration of the interaction of the comprehensive metallurgical properties of the blended burden charged into the furnace, the metallurgical properties of sinter are adjusted to ensure good comprehensive metallurgical properties of the blended burden. By adjusting the blast furnace operation to an appropriate regime, the proportion of comprehensive lump ore in the charged burden has been achieved to be ≥28%, and the blast furnace fuel ratio to be ≤515 kg per ton of iron. Full article

With the increasing adoption of traveling grate machines, increasing the proportion of pellets in blast furnace burdens has become a key strategy for reducing carbon emissions in ironmaking. Magnetite (Fe₃O₄) is not only the core raw material for pellet production but also serves as an important transition metal oxide catalyst, widely used in various fields due to its unique electronic structure and surface activity. This study employed density functional theory (DFT) and ab initio molecular dynamics (AIMD) to simulate the oxidation process of a Ca-doped Fe₃O₄ (110) surface at 1073 K, revealing the inhibition mechanism of the gangue element Ca and its impact on surface catalytic activity at the atomic scale. The results demonstrate that Ca segregates on the Fe₃O₄ surface, where it adsorbs and activates O₂ molecules, thereby delaying O₂ migration to active iron bridge sites and subsequent dissociation, which ultimately inhibits the oxidation kinetics. Electronic structure analysis indicates that the breakage of the O–O bond is accompanied by a sharp decrease in system energy (stabilizing at approximately −509 eV); it also clearly elucidates the charge transfer process and the mechanism of Fe-O bond formation during this exothermic reaction. This research provides a theoretical foundation for the development of fluxed pellets and high-temperature-resistant catalysts. Full article

The present paper discusses differences in the theoretical behavior of nonconventional biomasses during combustion according to their combustion parameters, focusing on their potential for sustainable energy valorization and their contribution to sustainable development. Data were obtained through thermogravimetric analysis (TGA) of biomasses from the local Galicia–North Portugal Euroregion. The samples tested were raw, nonwoody biomasses, specifically kiwi waste and gorse, and animal-derived biomasses, poultry and turkey manure. A wood pellet was also included as a reference conventional biofuel. Nonwoody biomass samples containing kaolin and calcium carbonate were also tested. Thermogravimetric analyses were performed on each biofuel under an oxidative atmosphere at different heating rates. With these data, different combustion parameters were calculated. The TGA results showed that the mean ignition temperature observed for animal-derived fuels was about 15 °C lower than for nonwoody biomasses at every heating rate, which indicates that they start to burn at lower temperatures. These animal-derived fuels generally presented better combustion parameters, suggesting that their combustion behavior is better; however, their high ash and moisture contents are problematic. These issues would be aggravated in real facilities, making them more difficult to use as fuel. The proportion of additives used had no effect on the parameters at lower heating rates, although they started to modify their tendency at 30 °C/min. For instance, the ignition index for non-additivated kiwi waste was 174.32 (wt. %/min³) × 10⁻³ compared to 143.78 (wt. %/min³) × 10⁻³ for kiwi with CaCO₃. Full article

This study presents the results of research on the pelleting process of pine sawdust with the addition of cherry stone waste, which was carried out using a flat-die pellet press in the context of fuel pellet production. The findings indicate that increasing the proportion of crushed cherry stones in the sawdust mixture from 10% to 20% reduced the pelletizer’s power demand by approximately 14% (from 3.35 to 2.86 kW) and by around 24% (from 3.79 to 2.86 kW), compared with the compaction of sawdust alone. The incorporation of 10% crushed cherry stone waste into pine sawdust slightly improved the kinetic strength of the pellets, increasing it by about 2% (from 94.6 to 96.60%). However, raising the cherry stone content further to 20% resulted in a moderate decrease in kinetic strength, by approximately 5% (from 96.60 to 91.37%). A similar trend was observed for pellet density: the addition of cherry stones (10–20%) slightly reduced the density by about 5.5% (from 1312.02 to 1241.65 kg·m⁻³), accompanied by a small decrease in bulk density. This study also confirmed the high calorific potential of crushed cherry stones, with a heat of combustion of 24.418 MJ·kg⁻¹ (dry basis) and a net calorific value of 22.326 MJ·kg⁻¹. Their incorporation at levels of 10–20% into sawdust mixtures increased the heat of combustion of the pellets by 0.42–0.84% (from 19.959 MJ·kg⁻¹ for sawdust alone at 15% moisture content to 20.042 MJ·kg⁻¹ with a 10% addition and 20.126 MJ·kg⁻¹ with a 20% addition). Moreover, the inclusion of cherry stone waste in the mixture had a beneficial effect on combustion performance, lowering emissions of harmful compounds such as CO, NO, and SO₂, due to the higher combustion temperature achieved. Consequently, the use of cherry stone waste as an additive to sawdust not only enhances the energetic and environmental performance of pellets but also provides an effective pathway for the management of large quantities of fruit industry residues. Full article

With the low-carbon transformation of the steel industry, using low-carbon raw materials is one of the important ways to achieve the “dual carbon” goals. Pellets have great physical and chemical properties as low-carbon furnace materials, which can significantly reduce blast furnace carbon emissions, exhibiting favorable overall environmental benefits. Increasing their proportion in the furnace is one of the important measures the steel industry can take to reduce carbon emissions. Binders play a critical role in the pelletizing process, and their properties directly influence pellet quality, thereby affecting the subsequent blast furnace smelting process. Compared with traditional bentonite, organic binders have become a potential alternative material due to their environmental friendliness, renewability, and ability to significantly reduce silica and alumina impurities in pellets while improving the iron grade. This work systematically elucidates the mechanism of organic binders, which primarily rely on the chemical adsorption of carboxyl groups and the hydrogen bonding of hydroxyl groups to enhance pellet strength, and then provides three typical examples of organic binders: lignosulfonate, carboxymethyl cellulose (CMC), and carboxymethyl starch (CMS). The common characteristic of these organic binders is that they are derived from renewable biomass through chemical modification, which is a derivative of biomass with renewable and abundant resources. However, the main problem with organic binders is that they burn and decompose at high temperatures. Current research has achieved technological breakthroughs in pellet quality by combining LD sludge, low-iron oxides, and nano-CaCO₃, including improved iron grade, reduced reduction swelling index (RSI), and enhanced preheating/roasting strength. Future studies should focus on optimizing the molecular structure of organic binders by increasing the degree of substitution of functional groups and the overall degree of polymerization. This approach aims to replace traditional bentonite while exploring applications of composite industrial solid wastes, effectively addressing the high-temperature strength loss issues in organic binders and providing strong support for the steel industry to achieve the green and low-carbon goals. Full article

Biomass is a key energy resource in the current context of climate and energy crises, due to its lower carbon footprint compared to fossil fuels. However, wood-based energy presents several drawbacks: public health concerns related to pollutant emissions from combustion, and questions about the sustainability of the resource given the increasing demand for cleaner fuels. This study investigates the combustion of mixtures of wood pellets (WPs) and barley straw pellets (BSPs) in a domestic biomass boiler, with the aim of evaluating how such blends affect pollutant emissions and energy production under standard boiler operation, without modifications. Pellets were characterized using a bomb calorimeter and thermogravimetric analysis (TGA), while gaseous and particulate emissions were measured at the chimney using gas analyzers and an Engine Exhaust Particle Sizer (EEPS), respectively. The results show that high BSP proportions (>50%) are not compatible with domestic biomass boilers, as they led to a significant increase in gaseous pollutant emission. However, blends with moderate BSP shares (10 and 25%) can be successfully used, offering benefits in terms of reduced pollutant emissions and improved sustainability. Additionally, infrared and high-speed cameras were installed above the boiler furnace, equipped with an optical window, to provide new insights into the combustion process. Full article

The black fig fly, Silba adipata (Diptera: Lonchaeidae), is an invasive pest recently introduced to Mexico, where it has rapidly spread across fig-producing regions. Despite its economic importance, effective monitoring strategies remain poorly studied. The present study evaluated the response of S. adipata adults to visual (color) and olfactory (attractant) cues under laboratory and field conditions in fig orchards. No significant color preferences were observed in laboratory choice tests using nine colors or in field trials using traps of four different colors. In the laboratory, traps containing 2% ammonium sulfate solution, torula yeast + borax, or Captor + borax, captured similar numbers of flies, whereas CeraTrap^® was less attractive. Traps containing 2% ammonium sulfate were more effective than 2% ammonium acetate, though attraction was comparable when ammonium acetate was diluted to 0.2% or 0.02%. In the field, torula yeast + borax and 2% ammonium sulfate mixed with fig latex outperformed the 2% ammonium sulfate solution alone, although seasonal variation influenced trap performance. A high proportion of field-captured females were sexually immature. Torula yeast + borax attracted high numbers of non-target insects and other lonchaeid species, which reduced its specificity. In contrast, traps containing fig latex mixtures showed higher selectivity, although some S. adipata adults could not be sexed due to specimen degradation. These findings highlight the value of torula yeast pellets and 2% ammonium sulfate plus fig latex for monitoring this pest, but merit validation in field studies performed over the entire crop cycle across both wet and dry seasons. Future studies should evaluate other proteins, ammonium salt combinations and fig latex volatiles in order to develop effective and selective monitoring or mass trapping tools targeted at this invasive pest. Full article