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27 pages, 1491 KiB  
Article
Spent Nuclear Fuel—Waste to Resource, Part 1: Effects of Post-Reactor Cooling Time and Novel Partitioning Strategies in Advanced Reprocessing on Highly Active Waste Volumes in Gen III(+) UOx Fuel Systems
by Alistair F. Holdsworth, Edmund Ireland and Harry Eccles
J. Nucl. Eng. 2025, 6(3), 29; https://doi.org/10.3390/jne6030029 - 5 Aug 2025
Viewed by 205
Abstract
Some of nuclear power’s primary detractors are the unique environmental challenges and impacts of radioactive wastes generated during fuel cycle operations. Key benefits of spent fuel reprocessing (SFR) are reductions in primary high active waste (HAW) masses, volumes, and lengths of radiotoxicity at [...] Read more.
Some of nuclear power’s primary detractors are the unique environmental challenges and impacts of radioactive wastes generated during fuel cycle operations. Key benefits of spent fuel reprocessing (SFR) are reductions in primary high active waste (HAW) masses, volumes, and lengths of radiotoxicity at the expense of secondary waste generation and high capital and operational costs. By employing advanced waste management and resource recovery concepts in SFR beyond the existing standard PUREX process, such as minor actinide and fission product partitioning, these challenges could be mitigated, alongside further reductions in HAW volumes, masses, and duration of radiotoxicity. This work assesses various current and proposed SFR and fuel cycle options as base cases, with further options for fission product partitioning of the high heat radionuclides (HHRs), rare earths, and platinum group metals investigated. A focus on primary waste outputs and the additional energy that could be generated by the reprocessing of high-burnup PWR fuel from Gen III(+) reactors using a simple fuel cycle model is used; the effects of 5- and 10-year spent fuel cooling times before reprocessing are explored. We demonstrate that longer cooling times are preferable in all cases except where short-lived isotope recovery may be desired, and that the partitioning of high-heat fission products (Cs and Sr) could allow for the reclassification of traditional raffinates to intermediate level waste. Highly active waste volume reductions approaching 50% vs. PUREX raffinate could be achieved in single-target partitioning of the inactive and low-activity rare earth elements, and the need for geological disposal could potentially be mitigated completely if HHRs are separated and utilised. Full article
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15 pages, 2903 KiB  
Article
Electrophysiological Substrate and Pulmonary Vein Reconnection Patterns in Recurrent Atrial Fibrillation: Comparing Thermal Strategies in Patients Undergoing Redo Ablation
by Krisztian Istvan Kassa, Adwity Shakya, Zoltan Som, Csaba Foldesi and Attila Kardos
J. Cardiovasc. Dev. Dis. 2025, 12(8), 298; https://doi.org/10.3390/jcdd12080298 - 2 Aug 2025
Viewed by 270
Abstract
Background: The influence of the initial ablation modality on pulmonary vein (PV) reconnection and substrate characteristics in redo procedures for recurrent atrial fibrillation (AF) remains unclear. We assessed how different thermal strategies—ablation index (AI)-guided radiofrequency (RF) versus cryoballoon (CB) ablation—affect remapping findings during [...] Read more.
Background: The influence of the initial ablation modality on pulmonary vein (PV) reconnection and substrate characteristics in redo procedures for recurrent atrial fibrillation (AF) remains unclear. We assessed how different thermal strategies—ablation index (AI)-guided radiofrequency (RF) versus cryoballoon (CB) ablation—affect remapping findings during redo pulmonary vein isolation (PVI). Methods: We included patients undergoing redo ablation between 2015 and 2024 with high-density electroanatomic mapping. Initial PVI modalities were retrospectively classified as low-power, long-duration (LPLD) RF; high-power, short-duration (HPSD) RF; or second-/third-generation CB. Reconnection sites were mapped using multielectrode catheters. Redo PVI was performed using AI-guided RF. Segments showing PV reconnection were reisolated; if all PVs remained isolated and AF persisted, posterior wall isolation was performed. Results: Among 195 patients (LPLD: 63; HPSD: 30; CB: 102), complete PVI at redo was observed in 0% (LPLD), 23.3% (HPSD), and 10.1% (CB) (p < 0.01 for LPLD vs. HPSD). Reconnection patterns varied by technique; LPLD primarily affected the right carina, while HPSD and CB showed reconnections at the LSPV ridge. Organized atrial tachycardia was least frequent after CB (12.7%, p < 0.002). Conclusion: Initial ablation strategy significantly influences PV reconnection and post-PVI arrhythmia patterns, with implications for redo procedure planning. Full article
(This article belongs to the Special Issue Atrial Fibrillation: New Insights and Perspectives)
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16 pages, 391 KiB  
Systematic Review
High-Protein Dietary Interventions in Heart Failure: A Systematic Review of Clinical and Functional Outcomes
by Lorraine S. Evangelista, Rebecca Meraz, Kelly L. Wierenga, Angelina P. Nguyen, Alona D. Angosta and Jennifer Kawi
Nutrients 2025, 17(14), 2361; https://doi.org/10.3390/nu17142361 - 18 Jul 2025
Viewed by 539
Abstract
Background: Heart failure (HF) is frequently associated with skeletal muscle wasting, reduced functional capacity, and malnutrition. High-protein diets offer a promising nutritional intervention to improve these outcomes in individuals with HF. Objective: This systematic review evaluated randomized controlled trials of high-protein dietary interventions [...] Read more.
Background: Heart failure (HF) is frequently associated with skeletal muscle wasting, reduced functional capacity, and malnutrition. High-protein diets offer a promising nutritional intervention to improve these outcomes in individuals with HF. Objective: This systematic review evaluated randomized controlled trials of high-protein dietary interventions in HF populations, with emphasis on intervention characteristics, quantitative benefits, and risk of bias. Methods: We conducted a comprehensive search in PubMed, MEDLINE, Embase, and Cochrane CENTRAL from inception to June 2025. Eligible studies enrolled adults (≥18 years) with HF, implemented high-protein regimens (≥1.1 g/kg/day or ~25–30% of energy), and reported on functional capacity, body composition, muscle strength, clinical outcomes, or biochemical markers. Two reviewers independently screened, extracted data, and assessed bias (Cochrane RoB 2). Heterogeneity in dosing, duration, and outcomes precluded meta-analysis; we therefore provide a narrative synthesis. Results: Ten trials (nine randomized controlled trials, one pilot) involving 1080 patients (median n = 38; range 21–652) were included. High-protein interventions yielded mean improvements in six-minute walk distance of +32 ± 14 m, lean body mass gain of +1.6 ± 0.9 kg, and 9 ± 4% enhancement in quality-of-life scores; muscle strength effects varied from −2% to +11%. Two studies reported an 18% reduction in HF readmissions (p < 0.05). The risk-of-bias assessment identified two low-risk, three moderate-risk, and one high-risk study. Key limitations include small sample sizes, varied protein dosing (1.1–1.5 g/kg/day), short follow-up (2–6 months), and outcome heterogeneity. Conclusions: High-protein dietary strategies appear to confer modest, clinically relevant gains in functional capacity, nutritional status, and HF readmission risk. Larger, well-powered trials with standardized dosing and longer follow-up are necessary to establish optimal protein targets, long-term efficacy, and safety. Full article
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7 pages, 2064 KiB  
Brief Report
Catheter Ablation of Premature Ventricular Contractions from Right Ventricular Outflow Tract: Concept and Application of Very-High-Power, Very-Short-Duration as a First-Line Ablation Strategy
by Shaojie Chen, Ramin Ebrahimi, Piotr Futyma, Sebastian Graeger, Gozal Mirzayeva, Anna Neumann, Daniel Schneppe, Luiz Vinícius Sartori, Sarah Janschel, Márcio Galindo Kiuchi, Martin Martinek and Helmut Pürerfellner
J. Clin. Med. 2025, 14(14), 5118; https://doi.org/10.3390/jcm14145118 - 18 Jul 2025
Viewed by 446
Abstract
This technical report presents a compelling case for the use of very-high-power, very-short-duration (VHPSD) radiofrequency ablation as a promising and efficient strategy for treating symptomatic premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT). The patient with frequent, symptomatic PVCs [...] Read more.
This technical report presents a compelling case for the use of very-high-power, very-short-duration (VHPSD) radiofrequency ablation as a promising and efficient strategy for treating symptomatic premature ventricular contractions (PVCs) originating from the right ventricular outflow tract (RVOT). The patient with frequent, symptomatic PVCs and a 24% burden underwent successful ablation using a 90 W/4 s recipe via the QDOT MICRO™ catheter. The procedure resulted in immediate and sustained elimination of PVCs, with only 4 s of ablation time, near-zero fluoroscopy, no complications, and no PVC recurrence at 6 months. VHPSD ablation, though originally developed for atrial fibrillation, demonstrated remarkable procedural efficiency, precision, and lesion efficacy in this case. Compared to standard power, long-duration (SPLD) ablation, VHPSD offers the potential to significantly reduce procedural time, minimize tissue edema, and lower complication risk, particularly advantageous in anatomically challenging areas or in situations where maintaining stable catheter contact for extended periods is difficult or unfeasible. This technical report suggests the transformative potential of VHPSD as a first-line ablation strategy for RVOT-PVCs, provided careful mapping and appropriate technique are used. It underscores the need for further prospective studies to validate its broader safety, efficacy, and role in PVC management, particularly in cases involving intramural origins. Full article
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13 pages, 2498 KiB  
Article
Evaluation of Dynamic On-Resistance and Trapping Effects in GaN on Si HEMTs Using Rectangular Gate Voltage Pulses
by Pasquale Cusumano, Alessandro Sirchia and Flavio Vella
Electronics 2025, 14(14), 2791; https://doi.org/10.3390/electronics14142791 - 11 Jul 2025
Cited by 1 | Viewed by 355
Abstract
Dynamic on-resistance (RON) of commercial GaN on Si normally off high-electron-mobility transistor (HEMT) devices is a very important parameter because it is responsible for conduction losses that limit the power conversion efficiency of high-power switching converters. Due to charge trapping effects, [...] Read more.
Dynamic on-resistance (RON) of commercial GaN on Si normally off high-electron-mobility transistor (HEMT) devices is a very important parameter because it is responsible for conduction losses that limit the power conversion efficiency of high-power switching converters. Due to charge trapping effects, dynamic RON is always higher than in DC, a behavior known as current collapse. To study how short-time dynamics of charge trapping and release affects RON we use rectangular 0–5 V gate voltage pulses with durations in the 1 μs to 100 μs range. Measurements are first carried out for single pulses of increasing duration, and it is found that RON depends on both pulse duration and drain current ID, being higher at shorter pulse durations and lower ID. For a train of five pulses, RON decreases with pulse number, reaching a steady state after a time interval of 100 μs. The response to a five pulses train is compared to that of a square-wave signal to study the time evolution of RON toward a dynamic steady state. The DC RON is also measured, and it is a factor of ten smaller than dynamic RON at the same ID. This confirms that a reduction in trapped charges takes place in DC as compared to the square-wave switching operation. Additional off-state stress tests at VDS = 55 V reveal the presence of residual surface traps in the drain access region, leading to four times increase in RON in comparison to pristine devices. Finally, the dynamic RON is also measured by the double-pulse test (DPT) technique with inductive load, giving a good agreement with results from single-pulse measurements. Full article
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20 pages, 4321 KiB  
Article
Cavity Flow Instabilities in a Purged High-Pressure Turbine Stage
by Lorenzo Da Valle, Bogdan Cezar Cernat and Sergio Lavagnoli
Int. J. Turbomach. Propuls. Power 2025, 10(3), 15; https://doi.org/10.3390/ijtpp10030015 - 7 Jul 2025
Viewed by 204
Abstract
As designers push engine efficiency closer to thermodynamic limits, the analysis of flow instabilities developed in a high-pressure turbine (HPT) is crucial to minimizing aerodynamic losses and optimizing secondary air systems. Purge flow, while essential for protecting turbine components from thermal stress, significantly [...] Read more.
As designers push engine efficiency closer to thermodynamic limits, the analysis of flow instabilities developed in a high-pressure turbine (HPT) is crucial to minimizing aerodynamic losses and optimizing secondary air systems. Purge flow, while essential for protecting turbine components from thermal stress, significantly impacts the overall efficiency of the engine and is strictly connected to cavity modes and rim-seal instabilities. This paper presents an experimental investigation of these instabilities in an HPT stage, tested under engine-representative flow conditions in the short-duration turbine rig of the von Karman Institute. As operating conditions significantly influence instability behavior, this study provides valuable insight for future turbine design. Fast-response pressure measurements reveal asynchronous flow instabilities linked to ingress–egress mechanisms, with intensities modulated by the purge rate (PR). The maximum strength is reached at PR = 1.0%, with comparable intensities persisting for higher rates. For lower PRs, the instability diminishes as the cavity becomes unsealed. An analysis based on the cross-power spectral density is applied to quantify the characteristics of the rotating instabilities. The speed of the asynchronous structures exhibits minimal sensitivity to the PR, approximately 65% of the rotor speed. In contrast, the structures’ length scale shows considerable variation, ranging from 11–12 lobes at PR = 1.0% to 14 lobes for PR = 1.74%. The frequency domain analysis reveals a complex modulation of these instabilities and suggests a potential correlation with low-engine-order fluctuations. Full article
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16 pages, 2472 KiB  
Article
Analysis of Ignition Spark Parameters Generated by Modern Ignition System in SI Engine Fueled by Ammonia
by Mariusz Chwist, Michał Gruca, Michał Pyrc and Borys Borowik
Energies 2025, 18(13), 3521; https://doi.org/10.3390/en18133521 - 3 Jul 2025
Viewed by 341
Abstract
This paper analyzes the influence of the number of ignition coils and spark discharge energy on the Coefficient of Variation of Indicated Mean Effective Pressure (COVIMEP) of an SI internal combustion piston engine. A modern electronically controlled induction ignition system is [...] Read more.
This paper analyzes the influence of the number of ignition coils and spark discharge energy on the Coefficient of Variation of Indicated Mean Effective Pressure (COVIMEP) of an SI internal combustion piston engine. A modern electronically controlled induction ignition system is used during the test. Two fuels are used in the experiment. The reference fuel is gasoline and the tested fuel is ammonia. For the traditional fuel, using an additional ignition coil does not improve COVIMEP. This parameter for gasoline has an almost constant value for different ignition system charging times. The situation is different for ammonia. This fuel requires high ignition energy. The use of one ignition coil demands a long charging time. For short charging times, unrepeatability of the engine cycles is unacceptable. The use of an additional ignition coil allowed to the charging coil timing to be shortened and the unrepeatable engine cycles to be reduced. This paper determined the maximum charging time of the used ignition coil, above which the spark parameters are worse. In addition, the influence of charging time and number of ignition coils on total spark energy, spark discharge duration, maximum spark power, and voltage during spark discharge for ammonia is presented. The data presented in this paper are developed based on measurements of current and voltage in the secondary winding of the ignition coil. A self-developed electronic device enabling the change in spark energy is used to control the ignition system. This paper also presents the construction of modern ignition systems, describes the functions of selected components, and briefly discusses their diagnostics. Full article
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20 pages, 2211 KiB  
Article
Electroacoustic Comparison and Optimization of Low-Power Impulse Sound-Source Needle Series Electrodes
by Xiao Du, Jing Zhou and Xu Gao
Energies 2025, 18(13), 3230; https://doi.org/10.3390/en18133230 - 20 Jun 2025
Viewed by 252
Abstract
The high-power drive of an impulse sound source with drilling makes the system’s life short and difficult to integrate. This report firstly establishes the pulse discharge experimental system and finite element model, and compares and verifies the typical parameters. Second, the study examines [...] Read more.
The high-power drive of an impulse sound source with drilling makes the system’s life short and difficult to integrate. This report firstly establishes the pulse discharge experimental system and finite element model, and compares and verifies the typical parameters. Second, the study examines how the energy storage capacitor’s charging voltage, discharge electrode gap, and liquid environment conductivity influence the electroacoustic performance of needle series electrodes. Subsequently, the optimal electrode configuration is identified under power constraints, yielding electroacoustic parameters and curves suitable for low-power impulsive sound sources. The findings reveal that the needle–plate electrode outperforms others in pre-breakdown duration, peak impulse wave strength, highest sound pressure level, and electroacoustic conversion efficiency. However, its higher power demand can be mitigated by lowering the charging voltage and narrowing the electrode gap. The charging voltage of the power-limited needle–plate electrode is only 3.5 kV, the impulse wave intensity reaches 1.27 MPa, and the peak system power is effectively controlled within 6.66 kW. A stable 288 dB SPL output is maintained up to 1 kHz, and above 250 dB in the wide bandwidth of 1–100 kHz. Needle–plate electrodes provide broadband excitation and high intensity SPL output despite power limitations. Full article
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23 pages, 9331 KiB  
Article
Non-Ideal Hall MHD Rayleigh–Taylor Instability in Plasma Induced by Nanosecond and Intense Femtosecond Laser Pulses
by Roman S. Zemskov, Maxim V. Barkov, Evgeniy S. Blinov, Konstantin F. Burdonov, Vladislav N. Ginzburg, Anton A. Kochetkov, Aleksandr V. Kotov, Alexey A. Kuzmin, Sergey E. Perevalov, Il’ya A. Shaikin, Sergey E. Stukachev, Ivan V. Yakovlev, Alexander A. Soloviev, Andrey A. Shaykin, Efim A. Khazanov, Julien Fuchs and Mikhail V. Starodubtsev
Plasma 2025, 8(2), 23; https://doi.org/10.3390/plasma8020023 - 10 Jun 2025
Viewed by 1372
Abstract
A pioneering detailed comparative study of the dynamics of plasma flows generated by high-power nanosecond and high-intensity femtosecond laser pulses with similar fluences of up to 3×104 J/cm2 is presented. The experiments were conducted on the petawatt laser facility [...] Read more.
A pioneering detailed comparative study of the dynamics of plasma flows generated by high-power nanosecond and high-intensity femtosecond laser pulses with similar fluences of up to 3×104 J/cm2 is presented. The experiments were conducted on the petawatt laser facility PEARL using two types of high-power laser radiation: femtosecond pulses with energy exceeding 10 J and a duration less than 60 fs, and nanosecond pulses with energy exceeding 10 J and a duration on the order of 1 ns. In the experiments, high-velocity (>100 km/s) flows of «femtosecond» (created by femtosecond laser pulses) and «nanosecond» plasmas propagated in a vacuum across a uniform magnetic field with a strength over 14 T. A significant difference in the dynamics of «femtosecond» and «nanosecond» plasma flows was observed: (i) The «femtosecond» plasma initially propagated in a vacuum (no B-field) as a collimated flow, while the «nanosecond» flow diverged. (ii) The «nanosecond» plasma interacting with external magnetic field formed a quasi-spherical cavity with Rayleigh–Taylor instability flutes. In the case of «femtosecond» plasma, such flutes were not observed, and the flow was immediately redirected into a narrow plasma sheet (or «tongue») propagating across the magnetic field at an approximately constant velocity. (iii) Elongated «nanosecond» and «femtosecond» plasma slabs interacting with a transverse magnetic field broke up into Rayleigh–Taylor «tongues». (iv) The ends of these «tongues» in the femtosecond case twisted into vortex structures aligned with the ion motion in the external magnetic field, whereas the «tongues» in the nanosecond case were randomly oriented. It was suggested that the twisting of femtosecond «tongues» is related to Hall effects. The experimental results are complemented by and consistent with numerical 3D magnetohydrodynamic simulations. The potential applications of these findings for astrophysical objects, such as short bursts in active galactic nuclei, are discussed. Full article
(This article belongs to the Special Issue New Insights into Plasma Theory, Modeling and Predictive Simulations)
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13 pages, 2864 KiB  
Article
Ultrafast Laser Beam Profile Characterization in the Front-End of the ELI-NP Laser System Using Image Features and Machine Learning
by Tayyab Imran
Photonics 2025, 12(5), 462; https://doi.org/10.3390/photonics12050462 - 9 May 2025
Viewed by 459
Abstract
Ultrafast laser systems, implemented at the ELI-NP, require exceptional beam quality and spatial stability due to their femtosecond pulse durations and extremely high peak powers. This work presents a diagnostic and computational framework for analyzing the ELI-NP Front-End beam characteristics, where spatial coherence [...] Read more.
Ultrafast laser systems, implemented at the ELI-NP, require exceptional beam quality and spatial stability due to their femtosecond pulse durations and extremely high peak powers. This work presents a diagnostic and computational framework for analyzing the ELI-NP Front-End beam characteristics, where spatial coherence and precise pulse shaping are essential for reliable amplification and experimental consistency. The methodology integrates classical beam diagnostics with image processing and machine learning tools to evaluate anomalies based on high-resolution beam profile images. We use centroid tracking to monitor pointing fluctuations, statistical intensity analysis to detect energy instabilities, and Sobel-based edge detection to evaluate beam sharpness and extract structural features from the beam image. Geometric parameters such as ellipticity, roundness, and symmetry indicators are extracted and examined over time. The system applies an unsupervised Isolation Forest algorithm to detect subtle or short-lived anomalies, identifying irregularities without relying on predefined thresholds. These diagnostics are supported by visual plots and statistical summaries, offering a clear picture of the beam’s behavior under real operating conditions. Results confirm that this integrated approach effectively captures major and minor beam instabilities, making it a practical tool for continuous monitoring and performance optimization in ultrafast laser systems. Full article
(This article belongs to the Section Lasers, Light Sources and Sensors)
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37 pages, 8477 KiB  
Review
Thermal Management for Unmanned Aerial Vehicle Payloads: Mechanisms, Systems, and Applications
by Ganapathi Pamula and Ashwin Ramachandran
Drones 2025, 9(5), 350; https://doi.org/10.3390/drones9050350 - 5 May 2025
Viewed by 3359
Abstract
Unmanned aerial vehicles (UAVs) are emerging as powerful tools for transporting temperature-sensitive payloads, including medical supplies, biological samples, and research materials, to remote or hard-to-reach locations. Effective thermal management is essential for maintaining payload integrity, especially during extended flights or harsh environmental conditions. [...] Read more.
Unmanned aerial vehicles (UAVs) are emerging as powerful tools for transporting temperature-sensitive payloads, including medical supplies, biological samples, and research materials, to remote or hard-to-reach locations. Effective thermal management is essential for maintaining payload integrity, especially during extended flights or harsh environmental conditions. This review presents a comprehensive analysis of temperature control mechanisms for UAV payloads, covering both passive and active strategies. Passive systems, such as phase-change materials and high-performance insulation, provide energy-efficient solutions for short-duration flights. In contrast, active systems, including thermoelectric cooling modules and Joule heating elements, offer precise temperature regulation for more demanding applications. We examined case studies that highlight the integration of these technologies in real-world UAV applications, such as vaccine delivery, blood sample transport, and in-flight polymerase chain reaction diagnostics. Additionally, we discussed critical design considerations, including power efficiency, payload capacity, and the impact of thermal management on flight endurance. We then presented an outlook on emerging technologies, such as hybrid power systems and smart feedback control loops, which promise to enhance UAV-based thermal management. This work aimed to guide researchers and practitioners in advancing thermal control technologies, enabling reliable, efficient, and scalable solutions for temperature-sensitive deliveries using UAVs. Full article
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19 pages, 6169 KiB  
Article
Chlorine Dioxide (ClO2)-Releasing Sachet for Preservation of Cherry Tomatoes
by Junseok Lee, Hojun Shin, Kambiz Sadeghi and Jongchul Seo
Molecules 2025, 30(9), 2041; https://doi.org/10.3390/molecules30092041 - 3 May 2025
Viewed by 548
Abstract
Chlorine dioxide (ClO2) is a powerful sterilizing agent that is widely used to prevent the spoilage of fresh foods during delivery and storage. However, its practical applications are hindered by a short sterilization duration, complex deployment processes, and high treatment costs. [...] Read more.
Chlorine dioxide (ClO2) is a powerful sterilizing agent that is widely used to prevent the spoilage of fresh foods during delivery and storage. However, its practical applications are hindered by a short sterilization duration, complex deployment processes, and high treatment costs. To address these challenges, an innovative ClO2 self-releasing sachet was developed, which was specifically designed for use in retail and wholesale markets. The sachet utilizes polyether block amide (PEBAX®) as a hydrophilic polymer to facilitate the dissociation of sodium chlorite (NaClO2) and citric acid (CA), which generates ClO2. A PEBAX/CA composite film was coated onto kraft paper to construct the sachet. This design extended the ClO2 release period to over 3 d, with a controllable release rate being achieved by adjusting the concentrations of NaClO2 and CA. In practical tests, the sachets inhibited fungal growth by >50% over 14 d at 20 °C within a corrugated box. Furthermore, they preserved the quality of the cherry tomatoes for 16 d during storage. These results demonstrate that the newly developed sachet offers an economical and user-friendly solution for fresh-food packaging, effectively preserving product quality. Full article
(This article belongs to the Special Issue Development of Food Packaging Materials)
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11 pages, 1094 KiB  
Article
Impact of Ablation Energy Sources on Perceived Quality of Life and Symptom in Atrial Fibrillation Patients: A Comparative Study
by Andrea Matteucci, Maurizio Russo, Marco Galeazzi, Claudio Pandozi, Michela Bonanni, Marco Valerio Mariani, Nicola Pierucci, Vincenzo Mirco La Fazia, Stefania Angela Di Fusco, Federico Nardi and Furio Colivicchi
J. Clin. Med. 2025, 14(8), 2741; https://doi.org/10.3390/jcm14082741 - 16 Apr 2025
Cited by 1 | Viewed by 694
Abstract
Background: Catheter ablation is a first-line treatment for rhythm control strategies in patients with atrial fibrillation (AF), with different energy sources available, including pulsed-field ablation (PFA), high-power short-duration radiofrequency (HPSD RF), conventional radiofrequency (RF), and cryoballoon ablation. Limited evidence exists on how [...] Read more.
Background: Catheter ablation is a first-line treatment for rhythm control strategies in patients with atrial fibrillation (AF), with different energy sources available, including pulsed-field ablation (PFA), high-power short-duration radiofrequency (HPSD RF), conventional radiofrequency (RF), and cryoballoon ablation. Limited evidence exists on how different ablation techniques affect patient-reported outcomes, such as patients’ quality of life (QoL) and perceived symptoms. This study aims to assess the impact of ablation energy sources on reported QoL and symptom perception after AF ablation. Methods: The study included 148 patients who underwent catheter ablation in different centers. Patients were divided into four groups according to the energy source used. Follow-up was conducted during the 6 months post-procedure. Patients were asked to complete a 20-item questionnaire evaluating quality of life, activity resumption, recovery process, perceived symptoms, and satisfaction. Comparative analyses were performed across energy groups, anesthesia types, and anesthetic drugs. Results: PFA patients reported the highest improvement in QoL scores compared to RF, HPSD RF, and cryoablation (p < 0.001). Activity resumption and symptom relief were significantly better in the PFA group compared to others (p < 0.001). Anesthesia type and anesthetic drug influenced QoL outcomes, with patients under general anesthesia showing higher QoL scores compared to deep sedation (p < 0.001). The energy source and anesthetic drug resulted in independent predictors of QoL improvement. Conclusions: Ablation energy source could impact patients’ perceived QoL and symptom relief after AF ablation. PFA demonstrated superior performance scores in QoL and symptom perception compared to other techniques. Anesthetic drugs also play a role in patient-reported outcomes and activity resumption. Full article
(This article belongs to the Special Issue Cardiac Ablation: Current Status and Future Perspectives)
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13 pages, 18986 KiB  
Article
Thermal Modelling of Metals and Alloys Irradiated by Pulsed Electron Beam: Focus on Rough, Heterogeneous and Multilayered Materials
by Andrea Lucchini Huspek, Valentina Mataloni, Ali Mohtashamifar, Luca Paterlini and Massimiliano Bestetti
J. Manuf. Mater. Process. 2025, 9(4), 130; https://doi.org/10.3390/jmmp9040130 - 15 Apr 2025
Viewed by 620
Abstract
Low-Energy High-Current Electron Beam (LEHCEB) is an innovative vacuum technology employed for the surface modification of conductive materials. Surface treatments by means of LEHCEB allow the melting and rapid solidification of a thin layer (up to ~10 μm) of material. The short duration [...] Read more.
Low-Energy High-Current Electron Beam (LEHCEB) is an innovative vacuum technology employed for the surface modification of conductive materials. Surface treatments by means of LEHCEB allow the melting and rapid solidification of a thin layer (up to ~10 μm) of material. The short duration of each pulse (2.5 μs) allows for the generation of high thermal rates, up to 109 K/s. Due to the peculiar features of LEHCEB source, in situ temperature monitoring inside the vacuum chamber is unfeasible, even with the most rapid IR pyrometers available on the market. Therefore, multiphysics simulations serve as a tool for predicting and assessing the thermal effects induced by electron beam irradiation. COMSOL Multiphysics was employed to study the thermal behaviour of metals and alloys at the sub-microsecond time scale by implementing both experimental power time profiles and semi-empirical electron penetration functions. Three case studies were considered: (a) 17-4 PH steel produced by Binder Jetting, (b) biphasic Al-Si13 alloy, and (c) Magnetron Sputtering Nb films on Ti substrate. The influence on the thermal effects of electron accelerating voltage and number of pulses was investigated, as well as the role of the physicochemical properties of the materials. Full article
(This article belongs to the Special Issue New Trends in Precision Machining Processes)
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21 pages, 7421 KiB  
Article
Study on the Spatial Distribution Patterns and Driving Forces of Rainstorm-Induced Flash Flood in the Yarlung Tsangpo River Basin
by Fei He, Chaolei Zheng, Xingguo Mo, Zhonggen Wang and Suxia Liu
Remote Sens. 2025, 17(8), 1393; https://doi.org/10.3390/rs17081393 - 14 Apr 2025
Viewed by 544
Abstract
Flash floods, typically triggered by natural events such as heavy rainfall, snowmelt, and dam failures, are characterized by abrupt onset, destructive power, unpredictability, and challenges in mitigation. This study investigates the spatial distribution patterns and driving mechanisms of rainstorm-induced flash flood disasters in [...] Read more.
Flash floods, typically triggered by natural events such as heavy rainfall, snowmelt, and dam failures, are characterized by abrupt onset, destructive power, unpredictability, and challenges in mitigation. This study investigates the spatial distribution patterns and driving mechanisms of rainstorm-induced flash flood disasters in the Yarlung Tsangpo River Basin (YTRB) by integrating topography, hydrometeorology, human activity data, and historical disaster records. Through a multi-method spatial analysis framework—including kernel density estimation, standard deviation ellipse, spatial autocorrelation (Moran’s I and Getis–Ord Gi*), and the optimal parameter geographic detector (OPGD) model (integrating univariate analysis and interaction detection)—we reveal multiscale disaster dynamics across county, township, and small catchment levels. Key findings indicate that finer spatial resolution (e.g., small catchment scale) enhances precision when identifying high-risk zones. Temporally, the number of rainstorm-induced flash floods increased significantly and disaster-affected areas expanded significantly from the 1980s to the 2010s, with a peak spatial dispersion observed during 2010–2019, reflecting a westward shift in disaster distribution. Spatial aggregation of flash floods persisted throughout the study period, concentrated in the central basin. Village density (TD) was identified as the predominant human activity factor, exhibiting nonlinear amplification through interactions with short-duration heavy rainfall (particularly 3 h [P3] and 6 h [P6] maximum precipitations) and GDP. These precipitation durations demonstrated compounding risk effects, where sustained rainfall intensity progressively heightened disaster potential. Topographic and ecological interactions, particularly between elevation (DEM) and vegetation type (VT), further modulate disaster intensity. These findings provide critical insights for risk zonation and targeted prevention strategies in high-altitude river basins. Full article
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