Search Results (231)

Soil structural instability in reservoir riparian zones, induced by water level fluctuations, threatens sustainable land use by accelerating land degradation. This study examined the impact of water-level variations on soil aggregate composition and stability based on key indicators, including water-stable aggregate content (WSAC), mean weight diameter (MWD), and geometric mean diameter (GMD). The Savinov dry sieving, Yoder wet sieving, and Le Bissonnais (LB) methods were employed for analysis. Results indicated that, with decreasing water levels and increasing soil layer, aggregates larger than 5 mm decreased, while aggregates smaller than 0.25 mm increased. Rising water levels and increasing soil layer corresponded to reductions in soil stability indicators (MWD, GMD, and WSAC), highlighting a trend toward soil structural instability. The LB method revealed the lowest aggregate stability under rapid wetting and the highest under slow wetting conditions. Correlation analysis showed that soil organic matter positively correlated with the relative mechanical breakdown index (RMI) (p < 0.05) and negatively correlated with the relative slaking index (RSI), whereas soil pH was negatively correlated with both RMI and RSI (p < 0.05). Comparative analysis of aggregate stability methods demonstrated that results from the dry sieving method closely resembled those from the SW treatment of the LB method, whereas the wet sieving method closely aligned with the FW (Fast Wetting) treatment of the LB method. The Le Bissonnais method not only reflected the outcomes of dry and wet sieving methods but also effectively distinguished the mechanisms of aggregate breakdown. The study concluded that prolonged flooding intensified aggregate dispersion, with mechanical breakdown influenced by water levels and soil layer. Dispersion and mechanical breakdown represent primary mechanisms of soil aggregate instability, further exacerbated by fluctuating water levels. By elucidating degradation mechanisms, this research provides actionable insights for preserving soil health, safeguarding water resources, and promoting sustainable agricultural in ecologically vulnerable reservoir regions of the Yangtze River Basin. Full article

Self-medication is a subject of global importance. If practiced responsibly, self-medication represents a part of self-care or positive care of an individual or a community in promoting their own health. However, today’s practices of self-medication are often inappropriate and irresponsible, and as such appear all over the world. Inappropriate self-medication can be connected with possible serious health risks and consequences. Therefore, it represents a global health issue. It can even generate additional health problems, which will eventually become a burden to healthcare systems and can induce significant costs, which also raises socioeconomic concerns. Hence, self-medication attracts the attention of researchers and practitioners globally in efforts to clarify the current status and define feasible measures that should be implemented to address this issue. This narrative review aims to give an overview of the situation in the field of self-medication globally, including current practices and attitudes, as well as implications for actions needed to improve this problem. A PubMed/MEDLINE search was conducted for articles published in the period from 1995 up to March 2025 using keywords “self-medication” or “selfmedication” alone or in combinations with terms related to specific subthemes related to self-medication, such as COVID-19, antimicrobials, healthcare professionals, and storing habits of medicines at home. Studies were included if self-medication was their main focus. Publications that only mentioned self-medication in different contexts, but not as their main focus, were excluded. Considering the outcomes of research on self-medication in various contexts, increasing awareness of responsible self-medication through education and informing, together with surveillance of particular medicines and populations, could lead to more appropriate and beneficial self-medication in the future. Full article

E-waste, a form of solid waste, contains many recyclable metals, but improper disposal can make it very harmful. Therefore, the recycling of e-waste is very important, and the willingness of residents to participate is crucial in e-waste recycling. Taking Jiangsu Province, China as an example, we used the theory of reasoned action (TRA) to construct a research model to investigate the factors influencing residents’ willingness to participate in e-waste recycling. The paper introduces impression management motivation and further reveals the application of the Hawthorne effect in e-waste recycling. The paper also introduces the awareness of benefits, which encompasses personal economic benefits, physical health benefits, and environmental benefits, with physical health benefits being ignored by most of the previous literature. In addition, knowledge and convenience are also introduced in this paper. A total of 400 valid responses were used to test the hypotheses of the structural equation model. It was found that all factors positively influenced residents’ willingness to engage in e-waste recycling. Attitude has a mediating role in the effects of convenience, knowledge, and awareness of benefits on willingness, and subjective norms have a mediating role in the effects of impression management motivation on willingness. The model explains 82.9% of the variance in residents’ willingness to recycle e-waste, surpassing the original TRA model’s explanatory power and confirming the strength of the extended framework. The study provides valuable policy implications for the government to promote e-waste recycling. Full article

Inclusion in play, physical education, outdoor life, organized sports, and other movement-based activities can promote resilience and support physical, emotional, and social well-being. These arenas are particularly important for reducing health disparities and preventing social marginalization across the lifespan. Yet, children and adolescents from vulnerable or disadvantaged backgrounds encounter persistent barriers to participation, rooted in broader inequalities related to their socioeconomic position, disability, gender, ethnicity, and access to supportive environments. This perspective outlines how inclusive movement contexts, when informed by developmental systems theory and resilience frameworks, can interrupt trajectories of marginalization and promote long-term equity in health, education, and work inclusion. We emphasize the need for interdisciplinary approaches, combining longitudinal and qualitative methods, to uncover how vulnerability and participation interact dynamically over time. By integrating insights from developmental science, education, public health, and spatial ecology, we identify strategic pathways for research and action. Addressing these challenges requires coordinated efforts across sectors and stakeholders to co-create inclusive, context-sensitive interventions. Full article

The COVID-19 pandemic has significantly altered consumer habits, particularly in relation to food choices. In this context, plant-based diets have gained prominence, driven by health, environmental, and ethical considerations. This study investigates the primary motivational and inhibitory factors influencing the consumption of plant-based foods among residents of the Galicia–Northern Portugal Euroregion. Utilizing the Theory of Reasoned Action, an extended model was proposed and tested through a quantitative survey. A total of 214 valid responses were collected via an online questionnaire distributed in Portuguese and Spanish. Linear regression analysis revealed that health awareness, animal welfare, and environmental concern significantly shape positive attitudes, which subsequently affect the intention to consume plant-based foods. Additionally, perceived barriers—such as lack of taste and insufficient information—were found to negatively influence intention. These findings contribute to the consumer behavior literature and provide strategic insights for stakeholders aiming to promote more sustainable dietary patterns in culturally connected cross-border regions. Full article

Humor is widely recognized for its positive effects on well-being, including stress reduction, mood enhancement, and cognitive benefits. Yet, the lack of reliable tools to objectively quantify amusement—particularly its temporal dynamics—has limited progress in this area. Existing measures often rely on self-report or coarse summary ratings, providing little insight into how amusement unfolds over time. To address this gap, we developed a Random Forest model to predict the intensity of amusement evoked by humorous video clips, based on participants’ facial expressions—particularly the co-activation of Facial Action Units 6 and 12 (“% Smile”)—and video features such as motion, saliency, and topic. Our results show that exposure to humorous content significantly increases “% Smile”, with amusement peaking toward the end of videos. Importantly, we observed emotional carry-over effects, suggesting that consecutive humorous stimuli can sustain or amplify positive emotional responses. Even when trained solely on humorous content, the model reliably predicted amusement intensity, underscoring the robustness of our approach. Overall, this study provides a novel, objective method to track amusement on a fine temporal scale, advancing the measurement of nonverbal emotional expression. These findings may inform the design of emotion-aware applications and humor-based therapeutic interventions to promote well-being and emotional health. Full article

The COVID-19 pandemic was a particularly challenging time for the construction industry as it experienced significant disruptions to operations, affecting various stakeholders. With various national and international health agencies promoting preventive measures, the construction industry struggled with the implementation of these measures due to the unique nature of the work involved in construction. This study aimed to highlight the ways in which stakeholders in the construction industry interacted and responded to the prescribed preventive measures through social media analysis. Using model-based clustering and structural topic modelling, this study provided insights into the prevalent discussion topics in social media around prevention measures in construction. In addition, sentiment analysis demonstrated interesting polarisation around the topic areas. Four prevalent topics that encapsulated the entirety of the social media data were identified, with two of the topics showing an upward trend, as expected, while the other two topics showed a contrasting downward trend. These findings offer practical value for construction managers and policymakers by revealing the effectiveness of different communication strategies and identifying areas where prevention measures faced resistance or acceptance. The sentiment polarisation patterns (50% positive, 40% negative) provide actionable insights for developing more targeted engagement approaches, while the topic evolution trends inform the timing and focus of safety communications. Construction organisations can leverage these insights to improve workplace safety protocols and enhance stakeholder buy-in for future health initiatives. This study lays the foundation for future studies to investigate the connections between the prevalent prevention and the interrelated dynamics within the conversation regarding COVID-19 prevention strategies in the construction sector. Full article

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract, which can result in several muscular complications, including sarcopenia, the loss of muscle mass, and impaired muscle function. Recently, postbiotics derived from lactic bacteria, such as Lactobacillus and Bifidobacterium, have emerged as potential therapeutic modulators for these complications. Postbiotics are bioactive metabolites, such as short-chain fatty acids (SCFAs), antimicrobial peptides, and other compounds produced by microorganisms during fermentation, which have anti-inflammatory, antioxidant, and metabolic regulatory effects. These metabolites are important due to their potential to positively influence muscle health in patients with IBD, mainly by reducing systemic and local inflammation, improving gut microbiota, and modulating muscle metabolism. Studies suggest that these postbiotics may help minimize muscle degradation and promote muscle tissue regeneration, assisting in the prevention or management of IBD-associated sarcopenia. Despite the promising results, challenges remain, such as variability in postbiotic production and the need for further clinical studies to establish clear therapeutic guidelines. This review article explores the mechanisms of action of postbiotics derived from lactic acid bacteria and their potential applications in the treatment of muscle complications in patients with IBD, highlighting future therapeutic perspectives. Full article

The cage tilapia farming boom in Kenya’s Lake Victoria region underscores its role in food security and economic growth. Success depends on understanding producer and consumer behaviors within the value chain. Using the Theory of Planned Behavior (TPB), this study examines how attitudes (evaluations of farming/consumption), subjective norms (social pressures), perceived behavioral control (confidence in actions), environmental awareness, and moral obligation shape decisions. A survey of 66 producers and 169 consumers, analyzed via structural equation modeling (SEM), reveals key drivers. Producers are driven by positive attitudes toward profitability, technical feasibility, and sustainability, reinforced by community norms and resource access, promoting sustainable practices. Consumers prioritize health, affordability, and accessibility of cage-farmed tilapia, with environmental and ethical factors less influential. These findings highlight opportunities for targeted interventions to enhance production, boost demand, and ensure sustainable aquaculture. Full article

The increase in the antimicrobial resistance (AMR) of Staphylococcus aureus (S. aureus) has become a global public health concern. This study globally monitored the large-scale longitudinal trend of AMR in S. aureus and examined the various human and environmental climate factors that influence the occurrence and spread of AMR in S. aureus, which might provide valuable data to support the development of a global surveillance system for S. aureus AMR and provide a theoretical basis for coordinated actions to control the emergence and development of AMR from multiple perspectives. There was a significantly positive correlation between the number of antibiotic resistance genes (ARGs) in S. aureus and the collection year, with a sharp increase in ARGs over time. The number of ARGs in S. aureus genomes significantly increased each decade, with the average number of ARGs per genome rising from 10.37 ± 3.55 before 1990 to 12.75 ± 4.04 after 2010, suggesting a growing problem of S. aureus AMR. The Spearman correlation results indicated that the human development index (HDI), antibiotic consumption, and mobile genetic elements (MGEs) were significantly associated with the AMR of S. aureus, and these factors played a crucial role in the emergence and development of S. aureus AMR. The results of structural equation modeling showed that the HDI significantly promoted an increase in antibiotic consumption, thereby indirectly enhancing the AMR of S. aureus. Antibiotic consumption also indirectly facilitated the progression of AMR in S. aureus through its impact on MGEs. The results of restricted cubic spline and generalized linear models showed that climate change also played a significant role in the progression of S. aureus AMR. In summary, this study provides a theoretical framework for monitoring the longitudinal trend of ARGs in S. aureus isolates and examining the possible influencing variables of ARGs in these isolates. Full article

Tennessee’s ecological diversity, spanning forests, farmland, and urban areas, provides an ideal foundation for applying the One Health approach, which integrates human, animal, and environmental health. This review examines Tennessee’s current One Health landscape, highlighting active initiatives, ongoing challenges, and future directions. Key efforts involve workforce development, disease surveillance, outbreak response, environmental conservation, and public education, led by a coalition of state agencies, universities, and the Tennessee One Health Committee. These programs promote cross-sector collaboration to address issues such as zoonotic diseases, climate change, land use shifts, and environmental contaminants. Notably, climate-driven changes, including rising temperatures and altered species distributions, pose increasing threats to health and ecological stability. Tennessee has responded with targeted monitoring programs and climate partnerships. Education is also a priority, with the growing integration of One Health into K–12 and higher education to build a transdisciplinary workforce. However, the state faces barriers, including limited funding for the One Health workforce, undefined workforce roles, and informal inter-agency data sharing. Despite these obstacles, Tennessee’s successful responses to outbreaks like avian influenza and rabies demonstrate the power of coordinated action. To strengthen its One Health strategy, the state must expand funding, formalize roles, improve data systems, and enhance biodiversity and climate resilience efforts positioning itself as a national leader in interdisciplinary collaborative solutions. Full article

Mother’s own milk (MOM) offers the highest protection for preterm and low birth weight infants. However, breastfeeding can be challenging during neonatal hospitalization. When MOM is unavailable, donor human milk (DHM) is the recommended alternative for feeding vulnerable neonates. Human milk banks (HMBs) collect, process, and deliver DHM, playing a key role in lactation support and promoting MOM availability. Although HMBs are expanding globally, scale-up remains hindered, restricting equitable DHM access. In Switzerland, despite the existence of eight HMBs, the western region lacked such a facility until 2022. To address this gap, an interdisciplinary team from the Lausanne University Hospital (CHUV) and the Swiss Red Cross Interregional Blood Transfusion Centre (TIR) collaborated to establish a regional HMB. This partnership leveraged both institutions’ available expertise, infrastructure, and resources. After two years of preparation, the CHUV Lactarium launched in 2022 with the support of the Department of Health and Social Action (DSAS) of the Canton of Vaud. This novel human milk bank–blood bank model is fully integrated into the hospital’s neonatal care, nutrition, and breastfeeding programs, operating under a strict quality and coordination system. Since its implementation, the HMB has met 100% of DHM needs, with an 80% breastfeeding bridging rate. It has had a positive impact on neonatal care, family engagement, professional interest, and community awareness of human milk. This case study illustrates how synergistic collaboration can help bridge gaps in establishing a safe, efficient, and equitable HMB model. It also offers a scalable framework adaptable to other settings. Full article

Despite the widespread use of crisis communication on social media during the COVID-19 pandemic, the mechanisms with which social media influence crisis-related behavioral coping have been insufficiently explored. By integrating the Social-Mediated Crisis Communication (SMCC) model with the Protective Action Decision Model (PADM), this study investigates how individuals’ protective actions are influenced by crisis-related information disseminated through social media, particularly focusing on the mediating effects of risk perception and emotional responses. This study examines two special periods: the initial outbreak (January–April 2020) and the subsequent period (May–December 2020). The results indicate that the dissemination of crisis-related information on social media platforms has significant positive associations with individuals’ risk perception, information sharing, and protective actions throughout the public health crisis. Notably, information gathering showed a positive relationship with protective actions during the initial outbreak. The study identified a chain mediation effect of emotional response and risk perception in the relationship between information dissemination and information sharing during and after the initial outbreak. Additionally, risk perception emerged as a partial mediator between information dissemination and information gathering during the subsequent period. This study enhances our understanding of the psychological mechanisms through which social media crisis communication influences collective coping responses in China, providing valuable insights for practitioners aiming to optimize crisis information dissemination strategies that promote sustainable protective behaviors on social media platforms. Full article

Among the many actions required to avert further intensification of today’s social, ecological and health crises is also the improvement of healthcare’s environmental sustainability, including in countries particularly vulnerable to such crises. The present study aimed to identify Namibian healthcare professionals’ knowledge, attitudes and practices, along with barriers and educational needs, as a foundation for context-relevant interventions. The study used a non-experimental, descriptive quantitative research design with an existing validated cross-sectional questionnaire as its data collection tool. Both purposive and snowball sampling were used to select healthcare professionals (n = 71) to participate in the quantitative online questionnaire. R (version 4.2.1) software was used to analyse the data from the completed questionnaires. The results showed that the Namibian healthcare professionals participating in this study have basic knowledge of and positive attitudes toward environmental sustainability in healthcare. However, various barriers to implementing strategies towards environmental sustainability exist that currently prevent the implementation of relevant practices. These should be overcome by the Namibian health system by providing the necessary frameworks, policies, measures and resources to drive improvements in environmental sustainability. Additionally, future and current healthcare professionals must receive training across all professional education levels to enable implementation in practice and effective advocacy and planetary health promotion. Full article

The role of nitric oxide (NO), soluble guanylate cyclase (sGC), and the cyclic guanosine monophosphate (cGMP) pathway in cardiovascular and renal health and disease is a complex issue. The impact of these biochemical pathways on the vascular tree is well established: the activation of sGC by NO promotes vasodilation and modulates vascular tone. Indeed, additional characteristics exist that lead physicians to believe there is a pleiotropic influence of this pathway on the functional activities and structural characteristics of human tissues and cells. Recently, sGC stimulators have demonstrated clinical efficacy in patients with worsening heart failure with reduced ejection fraction, improving cardiovascular death risk, re-hospitalization for HF, and all-cause mortality. These new outcome data have increased interest in understanding the potential pathophysiological mechanisms. The NO-sGC-cGMP axis may influence endothelial function, kidney performance, and cardiac muscle cell activity. The synergy of these actions could explain the positive effects of vericiguat on worsening HF. The aim of this narrative review was to provide a comprehensive insight into the pathophysiological mechanisms of action of NO-sGC-cGMP axis stimulators on cardiac muscle, endothelial cells, and kidneys. Full article